Mus musculus

27 known processes

Pik3c2b

phosphoinositide-3-kinase, class 2, beta polypeptide

(Aliases: C330011J12Rik,Gm199,PI3K-C2beta)

Pik3c2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small gtpase mediated signal transduction GO:0007264 97 0.081
aromatic compound catabolic process GO:0019439 286 0.072
purine containing compound metabolic process GO:0072521 311 0.062
ribonucleotide metabolic process GO:0009259 291 0.060
organic cyclic compound catabolic process GO:1901361 295 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.054
organophosphate catabolic process GO:0046434 232 0.053
ribose phosphate metabolic process GO:0019693 291 0.050
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.050
inorganic ion transmembrane transport GO:0098660 234 0.049
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.049
positive regulation of protein modification process GO:0031401 299 0.048
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.047
regulation of cell cycle GO:0051726 281 0.047
nucleoside metabolic process GO:0009116 246 0.046
purine nucleoside metabolic process GO:0042278 241 0.046
membrane organization GO:0061024 245 0.046
Worm
cation transmembrane transport GO:0098655 266 0.046
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.044
nucleotide metabolic process GO:0009117 332 0.042
purine ribonucleoside metabolic process GO:0046128 241 0.042
cellular lipid metabolic process GO:0044255 323 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.041
neuron death GO:0070997 154 0.041
Mouse
purine nucleotide metabolic process GO:0006163 302 0.041
purine ribonucleotide catabolic process GO:0009154 208 0.041
cell type specific apoptotic process GO:0097285 268 0.038
Mouse
heterocycle catabolic process GO:0046700 280 0.038
purine nucleoside catabolic process GO:0006152 205 0.038
nucleotide catabolic process GO:0009166 217 0.038
regulation of neuron death GO:1901214 134 0.038
Mouse
glycosyl compound catabolic process GO:1901658 206 0.037
positive regulation of nervous system development GO:0051962 221 0.036
regulation of neuron apoptotic process GO:0043523 122 0.035
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.035
positive regulation of ras gtpase activity GO:0032320 65 0.035
microtubule based process GO:0007017 236 0.034
regulation of cellular ketone metabolic process GO:0010565 66 0.034
positive regulation of cell development GO:0010720 237 0.033
neuron apoptotic process GO:0051402 142 0.033
Mouse
regulation of gtp catabolic process GO:0033124 113 0.033
regulation of ras gtpase activity GO:0032318 88 0.033
glycosyl compound metabolic process GO:1901657 246 0.032
guanosine containing compound catabolic process GO:1901069 144 0.032
cellular ketone metabolic process GO:0042180 84 0.032
ras protein signal transduction GO:0007265 77 0.032
positive regulation of gtp catabolic process GO:0033126 85 0.031
positive regulation of hydrolase activity GO:0051345 148 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
regulation of nucleoside metabolic process GO:0009118 130 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
ion transmembrane transport GO:0034220 361 0.029
Mouse
rho protein signal transduction GO:0007266 32 0.029
response to organonitrogen compound GO:0010243 246 0.029
gtp catabolic process GO:0006184 143 0.028
regulation of membrane potential GO:0042391 192 0.028
cellular amine metabolic process GO:0044106 44 0.028
negative regulation of cell development GO:0010721 169 0.028
microtubule cytoskeleton organization GO:0000226 157 0.028
regulation of nucleotide catabolic process GO:0030811 122 0.028
ribonucleoside metabolic process GO:0009119 245 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
apoptotic signaling pathway GO:0097190 306 0.028
organelle localization GO:0051640 179 0.027
regulation of apoptotic signaling pathway GO:2001233 197 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
transmembrane transport GO:0055085 412 0.027
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.026
positive regulation of cellular amine metabolic process GO:0033240 5 0.026
leukocyte differentiation GO:0002521 342 0.026
spermatogenesis GO:0007283 284 0.026
regulation of neuron differentiation GO:0045664 281 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
regulation of cell adhesion GO:0030155 154 0.025
Mouse
synapse organization GO:0050808 125 0.025
endomembrane system organization GO:0010256 147 0.025
sensory perception GO:0007600 245 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
transmission of nerve impulse GO:0019226 76 0.025
male gamete generation GO:0048232 285 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.024
amine metabolic process GO:0009308 45 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
forebrain development GO:0030900 302 0.023
regulation of secretion GO:0051046 274 0.023
skeletal system development GO:0001501 356 0.023
oxidation reduction process GO:0055114 342 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
cell division GO:0051301 120 0.023
Mouse
cellular response to lipid GO:0071396 145 0.023
nucleoside phosphate metabolic process GO:0006753 338 0.023
regulation of cell projection organization GO:0031344 206 0.023
gtp metabolic process GO:0046039 144 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.022
striated muscle tissue development GO:0014706 293 0.022
negative regulation of protein metabolic process GO:0051248 282 0.022
negative regulation of cell proliferation GO:0008285 296 0.022
purine containing compound catabolic process GO:0072523 213 0.022
cellular response to lipopolysaccharide GO:0071222 77 0.022
dna metabolic process GO:0006259 303 0.022
Mouse
positive regulation of transferase activity GO:0051347 167 0.022
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.021
synaptic transmission GO:0007268 329 0.021
regulation of cell cycle process GO:0010564 160 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.021
protein catabolic process GO:0030163 221 0.021
cell adhesion GO:0007155 329 0.021
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.021
cellular homeostasis GO:0019725 240 0.020
Mouse
stem cell proliferation GO:0072089 117 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
axonogenesis GO:0007409 274 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
nitrogen compound transport GO:0071705 271 0.020
action potential GO:0001508 78 0.020
regulation of proteolysis GO:0030162 164 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
protein localization to organelle GO:0033365 185 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
regulation of system process GO:0044057 200 0.019
establishment of organelle localization GO:0051656 122 0.019
cellular response to biotic stimulus GO:0071216 92 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.019
cellular response to molecule of bacterial origin GO:0071219 83 0.019
gland development GO:0048732 330 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
negative regulation of neuron apoptotic process GO:0043524 92 0.019
Mouse
nucleoside catabolic process GO:0009164 206 0.019
lymphocyte differentiation GO:0030098 242 0.019
skin development GO:0043588 220 0.018
telencephalon development GO:0021537 186 0.018
neural precursor cell proliferation GO:0061351 121 0.018
protein targeting GO:0006605 143 0.018
fatty acid metabolic process GO:0006631 121 0.018
protein ubiquitination GO:0016567 171 0.018
intracellular protein transport GO:0006886 204 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
protein maturation GO:0051604 176 0.018
cation transport GO:0006812 399 0.018
Mouse
positive regulation of programmed cell death GO:0043068 218 0.017
guanosine containing compound metabolic process GO:1901068 144 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
positive regulation of cell death GO:0010942 224 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
regulation of hydrolase activity GO:0051336 246 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
regulation of organelle organization GO:0033043 289 0.017
hematopoietic progenitor cell differentiation GO:0002244 143 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
macromolecule catabolic process GO:0009057 281 0.017
gene silencing GO:0016458 38 0.017
wnt signaling pathway GO:0016055 188 0.017
cellular protein catabolic process GO:0044257 155 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
muscle cell differentiation GO:0042692 261 0.017
response to lipopolysaccharide GO:0032496 128 0.017
camera type eye development GO:0043010 266 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
response to peptide hormone GO:0043434 127 0.016
negative regulation of immune system process GO:0002683 209 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
regulation of ras protein signal transduction GO:0046578 114 0.016
establishment of vesicle localization GO:0051650 81 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
positive regulation of rho gtpase activity GO:0032321 41 0.016
organelle assembly GO:0070925 177 0.016
bone development GO:0060348 120 0.016
cation homeostasis GO:0055080 212 0.016
Mouse
epithelial tube morphogenesis GO:0060562 303 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
sensory organ morphogenesis GO:0090596 242 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
epidermis development GO:0008544 187 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
Mouse
response to peptide GO:1901652 136 0.015
multicellular organismal signaling GO:0035637 91 0.015
neuron migration GO:0001764 122 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
calcium ion transport GO:0006816 159 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of secretion by cell GO:1903530 249 0.015
peptidyl amino acid modification GO:0018193 336 0.015
Mouse
rab protein signal transduction GO:0032482 1 0.015
maintenance of location GO:0051235 89 0.015
Worm
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
neural tube formation GO:0001841 108 0.015
myotube differentiation GO:0014902 105 0.015
b cell activation GO:0042113 161 0.015
Mouse
regulation of protein localization GO:0032880 231 0.015
neuronal action potential GO:0019228 54 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
neuromuscular process GO:0050905 99 0.015
sulfur compound metabolic process GO:0006790 100 0.015
respiratory tube development GO:0030323 167 0.014
regulation of intracellular transport GO:0032386 159 0.014
tube formation GO:0035148 140 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
glycoprotein metabolic process GO:0009100 116 0.014
cytoplasmic transport GO:0016482 234 0.014
regulation of rho gtpase activity GO:0032319 58 0.014
regulation of cellular response to stress GO:0080135 159 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
anion transport GO:0006820 177 0.014
regulation of hormone levels GO:0010817 211 0.014
divalent inorganic cation transport GO:0072511 178 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
myeloid cell differentiation GO:0030099 233 0.014
ossification GO:0001503 216 0.014
divalent metal ion transport GO:0070838 172 0.014
protein processing GO:0016485 163 0.014
homeostasis of number of cells GO:0048872 210 0.014
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.014
locomotory behavior GO:0007626 195 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
central nervous system neuron differentiation GO:0021953 162 0.014
regulation of transmembrane transport GO:0034762 128 0.014
Mouse
lipid biosynthetic process GO:0008610 179 0.014
Mouse Worm Fly
negative regulation of nervous system development GO:0051961 156 0.014
negative regulation of protein modification process GO:0031400 163 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
germ cell development GO:0007281 185 0.014
cellular response to acid chemical GO:0071229 68 0.014
stem cell differentiation GO:0048863 268 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
Fly
inorganic cation transmembrane transport GO:0098662 207 0.014
Mouse
spermatid differentiation GO:0048515 115 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
circulatory system process GO:0003013 197 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
positive regulation of growth GO:0045927 104 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
myelination GO:0042552 74 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
cellular chemical homeostasis GO:0055082 215 0.013
Mouse
positive regulation of cell cycle GO:0045787 92 0.013
negative regulation of molecular function GO:0044092 258 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
male sex differentiation GO:0046661 109 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
cellular protein complex assembly GO:0043623 116 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
response to acid chemical GO:0001101 111 0.013
regulation of protein kinase activity GO:0045859 232 0.013
Mouse
regulation of stem cell proliferation GO:0072091 78 0.013
response to radiation GO:0009314 165 0.013
respiratory system development GO:0060541 190 0.013
t cell activation GO:0042110 289 0.013
regulation of cell motility GO:2000145 236 0.013
gene silencing by rna GO:0031047 19 0.013
regulation of neuron projection development GO:0010975 169 0.013
response to inorganic substance GO:0010035 96 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
small molecule biosynthetic process GO:0044283 132 0.013
cellular response to topologically incorrect protein GO:0035967 25 0.013
metal ion homeostasis GO:0055065 189 0.012
Mouse
muscle tissue development GO:0060537 308 0.012
regulation of protein kinase b signaling GO:0051896 56 0.012
fertilization GO:0009566 127 0.012
spermatid development GO:0007286 108 0.012
regulation of kinase activity GO:0043549 249 0.012
Mouse
limb morphogenesis GO:0035108 149 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
Mouse Worm Fly
response to insulin GO:0032868 100 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
immune effector process GO:0002252 321 0.012
vesicle localization GO:0051648 86 0.012
macromolecule methylation GO:0043414 120 0.012
Mouse
chemotaxis GO:0006935 247 0.012
regulation of neural precursor cell proliferation GO:2000177 70 0.012
plasma membrane organization GO:0007009 90 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
lung development GO:0030324 164 0.012
appendage development GO:0048736 166 0.012
cytokine production GO:0001816 319 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
rhythmic process GO:0048511 174 0.012
positive regulation of protein kinase b signaling GO:0051897 32 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
posttranscriptional gene silencing GO:0016441 10 0.012
protein localization to membrane GO:0072657 108 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
negative regulation of neuron death GO:1901215 98 0.012
Mouse
tissue remodeling GO:0048771 102 0.012
chromatin organization GO:0006325 206 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
metencephalon development GO:0022037 89 0.012
pallium development GO:0021543 120 0.012
carbohydrate metabolic process GO:0005975 230 0.012
Mouse
cell substrate adhesion GO:0031589 130 0.012
Mouse
protein kinase b signaling GO:0043491 74 0.012
multicellular organismal homeostasis GO:0048871 164 0.011
methylation GO:0032259 134 0.011
Mouse
lipid localization GO:0010876 126 0.011
Worm
embryonic organ morphogenesis GO:0048562 276 0.011
peptidyl serine modification GO:0018209 83 0.011
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.011
activation of immune response GO:0002253 138 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
cellular ion homeostasis GO:0006873 165 0.011
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
stem cell development GO:0048864 219 0.011
regulation of cell migration GO:0030334 219 0.011
chromatin modification GO:0016568 187 0.011
innate immune response GO:0045087 157 0.011
lateral inhibition GO:0046331 1 0.011
hindbrain development GO:0030902 128 0.011
regionalization GO:0003002 337 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
retina development in camera type eye GO:0060041 119 0.011
peptide transport GO:0015833 133 0.011
response to light stimulus GO:0009416 135 0.011
negative regulation of organelle organization GO:0010639 90 0.011
cell cell adhesion GO:0098609 41 0.011
Mouse
response to endoplasmic reticulum stress GO:0034976 53 0.011
ensheathment of neurons GO:0007272 76 0.011
protein methylation GO:0006479 81 0.011
positive regulation of kinase activity GO:0033674 155 0.011
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.011
sequestering of metal ion GO:0051238 19 0.011
mitotic cell cycle GO:0000278 195 0.011
notch signaling pathway GO:0007219 71 0.011
endochondral bone morphogenesis GO:0060350 50 0.010
protein alkylation GO:0008213 81 0.010
cellularization GO:0007349 1 0.010
regulation of protein transport GO:0051223 163 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
establishment of synaptic vesicle localization GO:0097480 57 0.010
calcium ion homeostasis GO:0055074 127 0.010
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
regulation of mapk cascade GO:0043408 248 0.010
lymphocyte proliferation GO:0046651 164 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
Worm
developmental maturation GO:0021700 193 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
mrna metabolic process GO:0016071 84 0.010
primary neural tube formation GO:0014020 95 0.010

Pik3c2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.029
neurodegenerative disease DOID:1289 0 0.012
musculoskeletal system disease DOID:17 0 0.011
disease of metabolism DOID:0014667 0 0.010