Mus musculus

390 known processes

Isl1

ISL1 transcription factor, LIM/homeodomain

Isl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
auditory receptor cell fate determination GO:0042668 3 1.000
positive regulation of inner ear receptor cell differentiation GO:2000982 1 1.000
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 1.000
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 1.000
positive regulation of auditory receptor cell differentiation GO:0045609 1 1.000
peripheral nervous system neuron axonogenesis GO:0048936 3 1.000
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 1.000
noradrenergic neuron differentiation GO:0003357 6 1.000
forebrain neuron differentiation GO:0021879 52 1.000
Mouse
oligodendrocyte cell fate commitment GO:0021779 5 1.000
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 1.000
midbrain hindbrain boundary morphogenesis GO:0021555 4 1.000
mitral valve morphogenesis GO:0003183 4 1.000
ventral spinal cord interneuron differentiation GO:0021514 16 1.000
Mouse
embryonic heart tube formation GO:0003144 1 1.000
negative regulation of mesodermal cell fate specification GO:0042662 3 1.000
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 1.000
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 1.000
spinal cord association neuron differentiation GO:0021527 14 1.000
Mouse
hemangioblast cell differentiation GO:0060217 1 0.999
telencephalon development GO:0021537 186 0.999
Mouse
pyramidal neuron migration GO:0021852 1 0.999
regionalization GO:0003002 337 0.999
Human Mouse Fly
sensory organ morphogenesis GO:0090596 242 0.999
Mouse
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.999
pancreatic pp cell fate commitment GO:0003329 2 0.999
cell proliferation in hindbrain GO:0021534 10 0.999
pituitary gland development GO:0021983 38 0.999
embryonic organ morphogenesis GO:0048562 276 0.999
Mouse
endocardial cell differentiation GO:0060956 4 0.999
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.999
closure of optic fissure GO:0061386 2 0.999
autonomic nervous system development GO:0048483 43 0.999
forebrain generation of neurons GO:0021872 63 0.999
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.999
embryonic skeletal system development GO:0048706 120 0.999
Mouse
pancreatic pp cell differentiation GO:0003312 2 0.999
eye photoreceptor cell differentiation GO:0001754 41 0.999
cardiac muscle cell differentiation GO:0055007 69 0.999
Zebrafish
central nervous system neuron differentiation GO:0021953 162 0.999
spinal cord motor neuron cell fate specification GO:0021520 13 0.999
astrocyte fate commitment GO:0060018 4 0.999
cell fate specification GO:0001708 72 0.999
forebrain neuron fate commitment GO:0021877 13 0.999
Mouse
hypothalamus development GO:0021854 16 0.998
sympathetic nervous system development GO:0048485 22 0.998
spinal cord development GO:0021510 81 0.998
diencephalon development GO:0021536 63 0.998
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.998
Mouse
neural crest cell development GO:0014032 48 0.998
dentate gyrus development GO:0021542 14 0.998
Mouse
lateral line nerve development GO:0048892 1 0.998
hindbrain tangential cell migration GO:0021934 2 0.998
skeletal muscle cell differentiation GO:0035914 66 0.998
forebrain cell migration GO:0021885 58 0.998
Mouse
axon guidance GO:0007411 141 0.998
cerebral cortex neuron differentiation GO:0021895 19 0.998
Mouse
glial cell fate specification GO:0021780 5 0.998
spinal cord motor neuron differentiation GO:0021522 35 0.998
schwann cell development GO:0014044 22 0.998
locus ceruleus development GO:0021703 1 0.998
pancreatic a cell fate commitment GO:0003326 2 0.997
ventral spinal cord interneuron fate commitment GO:0060579 14 0.997
Mouse
oligodendrocyte differentiation GO:0048709 53 0.997
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.997
cerebral cortex development GO:0021987 86 0.997
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.997
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.997
neuron projection guidance GO:0097485 141 0.997
stem cell fate specification GO:0048866 3 0.997
cardiac cell fate determination GO:0060913 2 0.997
oligodendrocyte development GO:0014003 20 0.997
primary prostatic bud elongation GO:0060516 2 0.997
cell differentiation in hindbrain GO:0021533 24 0.997
Mouse
limbic system development GO:0021761 72 0.996
Mouse
regulation of auditory receptor cell differentiation GO:0045607 4 0.996
septum primum development GO:0003284 4 0.996
retinal ganglion cell axon guidance GO:0031290 18 0.996
cerebellar granule cell precursor proliferation GO:0021930 10 0.996
cerebral cortex cell migration GO:0021795 44 0.996
Mouse
peripheral nervous system development GO:0007422 53 0.996
regulation of mast cell differentiation GO:0060375 3 0.996
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.996
Zebrafish
camera type eye development GO:0043010 266 0.996
Mouse
neural crest cell migration GO:0001755 32 0.996
atrial septum primum morphogenesis GO:0003289 3 0.996
oculomotor nerve morphogenesis GO:0021622 2 0.995
embryonic heart tube left right pattern formation GO:0060971 5 0.995
forebrain development GO:0030900 302 0.995
endodermal cell fate commitment GO:0001711 12 0.995
glial cell development GO:0021782 54 0.995
telencephalon cell migration GO:0022029 55 0.995
Mouse
lateral motor column neuron migration GO:0097477 3 0.995
Mouse
ureteric bud morphogenesis GO:0060675 62 0.995
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.995
olfactory bulb development GO:0021772 30 0.995
Mouse
myelination in peripheral nervous system GO:0022011 19 0.995
oligodendrocyte cell fate specification GO:0021778 5 0.994
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.994
spinal cord motor neuron migration GO:0097476 4 0.994
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.994
mitral valve development GO:0003174 4 0.994
auditory receptor cell fate specification GO:0042667 1 0.994
regulation of astrocyte differentiation GO:0048710 20 0.994
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.993
gastrulation GO:0007369 116 0.993
Mouse
hindbrain development GO:0030902 128 0.993
Mouse
inner cell mass cellular morphogenesis GO:0001828 1 0.993
regulation of lens epithelial cell proliferation GO:2001109 1 0.993
central nervous system neuron development GO:0021954 67 0.992
Mouse
cell fate commitment GO:0045165 210 0.992
rhombomere development GO:0021546 8 0.992
neuron fate specification GO:0048665 30 0.992
cardiac endothelial cell differentiation GO:0003348 4 0.992
mesenchymal cell differentiation GO:0048762 107 0.992
metanephric nephron tubule formation GO:0072289 4 0.992
glial cell fate commitment GO:0021781 14 0.991
mesenchyme morphogenesis GO:0072132 32 0.991
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.991
striated muscle tissue development GO:0014706 293 0.991
lens morphogenesis in camera type eye GO:0002089 24 0.991
peripheral nervous system neuron development GO:0048935 9 0.991
neuroblast proliferation GO:0007405 49 0.990
embryonic viscerocranium morphogenesis GO:0048703 8 0.990
Mouse
formation of primary germ layer GO:0001704 77 0.990
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.989
forebrain morphogenesis GO:0048853 17 0.989
rhombomere morphogenesis GO:0021593 2 0.989
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.989
dendrite development GO:0016358 115 0.988
Fly
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.988
regulation of gliogenesis GO:0014013 50 0.987
eye photoreceptor cell development GO:0042462 31 0.987
neural crest cell differentiation GO:0014033 54 0.987
axonogenesis GO:0007409 274 0.987
appendage development GO:0048736 166 0.987
Mouse
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.987
Mouse
neuron maturation GO:0042551 29 0.987
mesenchymal cell development GO:0014031 93 0.986
stem cell development GO:0048864 219 0.986
regulation of neuron projection development GO:0010975 169 0.986
mesoderm formation GO:0001707 62 0.986
noradrenergic neuron development GO:0003358 3 0.986
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.986
somatic motor neuron differentiation GO:0021523 6 0.985
Mouse
kidney development GO:0001822 213 0.985
Mouse
kidney epithelium development GO:0072073 121 0.985
Mouse
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.984
nephron tubule morphogenesis GO:0072078 68 0.984
Mouse
retinal rod cell differentiation GO:0060221 2 0.983
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.983
peripheral nervous system neuron differentiation GO:0048934 9 0.983
developmental growth involved in morphogenesis GO:0060560 138 0.983
Zebrafish Mouse
neuron projection extension GO:1990138 64 0.983
Zebrafish Mouse
endodermal cell fate specification GO:0001714 4 0.983
hair cell differentiation GO:0035315 40 0.983
olfactory bulb interneuron differentiation GO:0021889 12 0.982
neural tube closure GO:0001843 90 0.982
Mouse
positive regulation of transcription via serum response element binding GO:0010735 1 0.982
inner cell mass cell differentiation GO:0001826 7 0.982
mesodermal cell fate commitment GO:0001710 17 0.982
dendrite extension GO:0097484 3 0.982
motor neuron migration GO:0097475 4 0.982
Mouse
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.982
limb development GO:0060173 166 0.981
Mouse
regulation of neural retina development GO:0061074 3 0.981
positive regulation of ureteric bud formation GO:0072107 3 0.981
deltoid tuberosity development GO:0035993 3 0.981
endocrine system development GO:0035270 98 0.980
dorsal spinal cord development GO:0021516 20 0.980
Mouse
atrioventricular valve morphogenesis GO:0003181 13 0.980
negative regulation of gliogenesis GO:0014014 23 0.979
cerebral cortex tangential migration GO:0021800 7 0.978
Mouse
gliogenesis GO:0042063 141 0.978
cardioblast migration to the midline involved in heart field formation GO:0060975 1 0.978
mesodermal cell differentiation GO:0048333 22 0.978
amacrine cell differentiation GO:0035881 5 0.977
nerve development GO:0021675 67 0.977
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.977
metanephric nephron morphogenesis GO:0072273 19 0.976
Mouse
lens epithelial cell proliferation GO:0097166 1 0.976
nephron morphogenesis GO:0072028 69 0.976
Mouse
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.976
cerebellar cortex development GO:0021695 48 0.976
Mouse
forebrain regionalization GO:0021871 25 0.975
Mouse
embryonic eye morphogenesis GO:0048048 29 0.975
cardiac right ventricle formation GO:0003219 3 0.975
medial motor column neuron differentiation GO:0021526 2 0.975
Mouse
mesenchymal to epithelial transition GO:0060231 12 0.974
astrocyte differentiation GO:0048708 43 0.974
cerebral cortex radially oriented cell migration GO:0021799 31 0.974
Mouse
regulation of neuroblast proliferation GO:1902692 27 0.974
myelination GO:0042552 74 0.974
nose development GO:0043584 12 0.974
visceral motor neuron differentiation GO:0021524 3 0.973
visceral serous pericardium development GO:0061032 2 0.973
metanephric nephron development GO:0072210 34 0.973
Mouse
ear morphogenesis GO:0042471 118 0.973
regulation of ureteric bud formation GO:0072106 3 0.972
enteric nervous system development GO:0048484 11 0.971
renal tubule development GO:0061326 87 0.971
Mouse
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.970
spinal cord dorsal ventral patterning GO:0021513 23 0.970
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.970
positive regulation of transcription by glucose GO:0046016 3 0.970
negative regulation of astrocyte differentiation GO:0048712 10 0.969
stem cell differentiation GO:0048863 268 0.969
negative regulation of nervous system development GO:0051961 156 0.968
schwann cell differentiation GO:0014037 26 0.968
regulation of neuron differentiation GO:0045664 281 0.968
cerebellar cortex formation GO:0021697 22 0.967
Mouse
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.966
intestinal epithelial structure maintenance GO:0060729 4 0.966
innervation GO:0060384 22 0.966
regulation of transcription involved in cell fate commitment GO:0060850 15 0.965
cardiac atrium morphogenesis GO:0003209 23 0.965
cerebellar purkinje cell layer development GO:0021680 26 0.964
Mouse
digestive system development GO:0055123 200 0.964
Zebrafish Mouse Worm
olfactory lobe development GO:0021988 32 0.964
Mouse
neuron migration GO:0001764 122 0.964
Mouse
globus pallidus development GO:0021759 2 0.964
negative regulation of gastrulation GO:2000542 3 0.964
stem cell maintenance GO:0019827 130 0.963
regulation of cartilage development GO:0061035 44 0.962
bmp signaling pathway GO:0030509 93 0.961
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.961
sensory system development GO:0048880 3 0.960
regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification GO:0060807 1 0.960
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.960
ventricular cardiac muscle tissue development GO:0003229 38 0.959
ventricular cardiac muscle cell differentiation GO:0055012 17 0.959
ureter morphogenesis GO:0072197 4 0.958
sinoatrial node cell differentiation GO:0060921 3 0.958
regulation of chondrocyte differentiation GO:0032330 33 0.958
negative regulation of glial cell proliferation GO:0060253 4 0.958
erythrocyte differentiation GO:0030218 88 0.957
hindbrain morphogenesis GO:0021575 46 0.957
Mouse
thalamus development GO:0021794 11 0.956
telencephalon regionalization GO:0021978 14 0.955
Mouse
oculomotor nerve development GO:0021557 4 0.955
camera type eye photoreceptor cell differentiation GO:0060219 15 0.955
endocardial cushion to mesenchymal transition GO:0090500 5 0.954
skeletal muscle organ development GO:0060538 163 0.953
cranial nerve development GO:0021545 41 0.951
nephron tubule development GO:0072080 84 0.951
Mouse
central nervous system segmentation GO:0035283 3 0.951
forebrain neuron development GO:0021884 30 0.949
Mouse
gastrulation with mouth forming second GO:0001702 29 0.949
Mouse
ensheathment of neurons GO:0007272 76 0.949
negative regulation of synapse maturation GO:2000297 2 0.948
inner ear receptor cell differentiation GO:0060113 61 0.948
renal capsule specification GO:0072130 1 0.947
adenohypophysis development GO:0021984 14 0.947
cardiac ventricle development GO:0003231 83 0.947
retina morphogenesis in camera type eye GO:0060042 45 0.946
Mouse
regulation of glial cell differentiation GO:0045685 41 0.946
ventricular cardiac myofibril assembly GO:0055005 3 0.945
axonal fasciculation GO:0007413 15 0.944
positive regulation of keratinocyte proliferation GO:0010838 4 0.944
cardiac chamber development GO:0003205 108 0.943
transdifferentiation GO:0060290 1 0.943
regulation of mesodermal cell fate specification GO:0042661 5 0.943
tendon cell differentiation GO:0035990 4 0.943
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.942
axon target recognition GO:0007412 4 0.942
smoothened signaling pathway GO:0007224 105 0.942
positive regulation of glial cell differentiation GO:0045687 21 0.941
mesonephric tubule morphogenesis GO:0072171 63 0.941
Mouse
skeletal system morphogenesis GO:0048705 203 0.941
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.940
subpallium neuron fate commitment GO:0060163 2 0.940
anterior commissure morphogenesis GO:0021960 6 0.940
negative regulation of muscle cell apoptotic process GO:0010656 9 0.940
trophectodermal cell differentiation GO:0001829 21 0.940
negative regulation of cell development GO:0010721 169 0.939
cell differentiation in spinal cord GO:0021515 53 0.939
rhombomere 5 development GO:0021571 4 0.939
thymus development GO:0048538 41 0.939
muscle tissue development GO:0060537 308 0.937
regulation of cellular amino acid metabolic process GO:0006521 5 0.937
motor neuron axon guidance GO:0008045 26 0.936
Mouse Fly
cartilage development GO:0051216 140 0.936
lens development in camera type eye GO:0002088 62 0.936
mesoderm morphogenesis GO:0048332 64 0.934
limb morphogenesis GO:0035108 149 0.934
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.934
hypothalamus cell migration GO:0021855 5 0.933
regulation of gastrulation GO:0010470 16 0.932
Mouse
sclerotome development GO:0061056 4 0.932
pancreatic a cell differentiation GO:0003310 7 0.930
Zebrafish
megakaryocyte differentiation GO:0030219 26 0.929
organ growth GO:0035265 117 0.929
Mouse
cardiogenic plate morphogenesis GO:0003142 1 0.928
cardiac ventricle formation GO:0003211 8 0.928
glial cell differentiation GO:0010001 131 0.927
pulmonary myocardium development GO:0003350 3 0.926
endocardium formation GO:0060214 4 0.925
intrahepatic bile duct development GO:0035622 2 0.923
clara cell differentiation GO:0060486 4 0.922
ventral spinal cord interneuron specification GO:0021521 11 0.922
Mouse
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.922
cerebral cortex gabaergic interneuron development GO:0021894 6 0.922
Mouse
comma shaped body morphogenesis GO:0072049 5 0.921
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.921
granulocyte colony stimulating factor production GO:0071611 1 0.921
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.920
Mouse
atrial cardiac muscle cell differentiation GO:0055011 2 0.919
Zebrafish
forebrain ventricular zone progenitor cell division GO:0021869 6 0.919
negative regulation of neuron projection development GO:0010977 50 0.918
positive regulation of nervous system development GO:0051962 221 0.917
Mouse
iris morphogenesis GO:0061072 2 0.917
regulation of stem cell proliferation GO:0072091 78 0.916
endodermal cell fate determination GO:0007493 2 0.916
cellular amine metabolic process GO:0044106 44 0.915
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.914
cerebellar purkinje cell granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation GO:0021937 6 0.912
Mouse
determination of heart left right asymmetry GO:0061371 48 0.912
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.910
Fly
chondrocyte hypertrophy GO:0003415 4 0.909
s shaped body morphogenesis GO:0072050 6 0.908
Mouse
appendage morphogenesis GO:0035107 149 0.908
Mouse
cardiac muscle tissue development GO:0048738 130 0.908
auditory receptor cell differentiation GO:0042491 37 0.908
mesodermal cell fate specification GO:0007501 11 0.907
ascending aorta morphogenesis GO:0035910 3 0.906
gabaergic neuron differentiation GO:0097154 11 0.905
Zebrafish Mouse
renal vesicle induction GO:0072034 3 0.904
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.903
Mouse
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.902
Mouse
developmental induction GO:0031128 34 0.901
negative regulation of glial cell differentiation GO:0045686 21 0.896
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.896
mesenchyme development GO:0060485 152 0.895
glial cell migration GO:0008347 7 0.895
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.894
regulation of organ morphogenesis GO:2000027 144 0.893
cardiac cell fate specification GO:0060912 2 0.893
positive regulation of neuron maturation GO:0014042 2 0.892
head morphogenesis GO:0060323 34 0.892
Worm
cell proliferation in external granule layer GO:0021924 10 0.892
cardiac chamber formation GO:0003207 10 0.890
ureteric bud development GO:0001657 94 0.888
Mouse
inner ear morphogenesis GO:0042472 101 0.888
regulation of heart morphogenesis GO:2000826 22 0.887
regulation of cardiac cell fate specification GO:2000043 1 0.887
action potential GO:0001508 78 0.885
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.885
pancreas development GO:0031016 57 0.885
cell cell signaling involved in cell fate commitment GO:0045168 35 0.885
epidermis development GO:0008544 187 0.882
Mouse
endoderm formation GO:0001706 20 0.879
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.879
ventral spinal cord development GO:0021517 48 0.877
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.876
respiratory system development GO:0060541 190 0.876
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.876
rhombomere 2 development GO:0021568 2 0.875
somatotropin secreting cell differentiation GO:0060126 4 0.873
trochlear nerve development GO:0021558 3 0.873
embryonic skeletal system morphogenesis GO:0048704 91 0.872
Mouse
muscle tissue morphogenesis GO:0060415 53 0.872
photoreceptor cell fate commitment GO:0046552 2 0.871
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.871
positive regulation of heart growth GO:0060421 18 0.871
embryonic epithelial tube formation GO:0001838 130 0.868
Mouse
outflow tract morphogenesis GO:0003151 53 0.868
positive regulation of synaptic plasticity GO:0031915 4 0.867
endothelial cell differentiation GO:0045446 41 0.867
rhombomere 3 morphogenesis GO:0021658 2 0.866
regulation of inner ear receptor cell differentiation GO:2000980 5 0.865
ear development GO:0043583 200 0.863
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.863
erythrocyte maturation GO:0043249 6 0.863
epithelial tube formation GO:0072175 130 0.861
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.860
regulation of cerebellar granule cell precursor proliferation GO:0021936 12 0.860
Mouse
cerebral cortex radial glia guided migration GO:0021801 17 0.860
retina development in camera type eye GO:0060041 119 0.860
Mouse
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.860
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.859
Mouse
negative regulation of osteoblast differentiation GO:0045668 30 0.859
cell proliferation in forebrain GO:0021846 30 0.859
Mouse
positive regulation of bmp signaling pathway GO:0030513 23 0.857
ectoderm formation GO:0001705 3 0.857
Mouse
positive regulation of rhodopsin gene expression GO:0045872 2 0.857
aortic valve morphogenesis GO:0003180 4 0.856
medulla oblongata development GO:0021550 3 0.855
lung smooth muscle development GO:0061145 2 0.854
renal vesicle development GO:0072087 17 0.853
Mouse
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.853
neurohypophysis development GO:0021985 2 0.850
branchiomeric skeletal muscle development GO:0014707 3 0.850
gland development GO:0048732 330 0.849
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.849
equilibrioception GO:0050957 3 0.848
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.847
ureteric bud formation GO:0060676 7 0.847
brain segmentation GO:0035284 3 0.845
regulation of epidermal cell differentiation GO:0045604 21 0.844
renal vesicle morphogenesis GO:0072077 15 0.842
Mouse
cardiac neural crest cell development involved in heart development GO:0061308 7 0.842
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.842
atrial cardiac muscle cell development GO:0055014 2 0.842
diencephalon morphogenesis GO:0048852 6 0.839
cardiac pacemaker cell fate commitment GO:0060927 1 0.839
somite rostral caudal axis specification GO:0032525 13 0.838
Mouse
regulation of hippo signaling GO:0035330 1 0.835
cell maturation GO:0048469 127 0.835
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.834
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.833
response to heparin GO:0071503 1 0.832
enteroendocrine cell differentiation GO:0035883 16 0.826
Zebrafish
neuroblast differentiation GO:0014016 2 0.825
regulation of retina development in camera type eye GO:1902866 3 0.823
preganglionic parasympathetic nervous system development GO:0021783 17 0.822
peptide transport GO:0015833 133 0.821
Rat
renal system development GO:0072001 225 0.819
Mouse
secondary heart field specification GO:0003139 6 0.818
Human
myeloid cell differentiation GO:0030099 233 0.818
regulation of stem cell division GO:2000035 4 0.815
heart formation GO:0060914 16 0.814
cellular response to heparin GO:0071504 1 0.813
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.811
cardioblast migration GO:0003260 1 0.811
midbrain development GO:0030901 35 0.803
Mouse
regulation of striated muscle cell apoptotic process GO:0010662 11 0.801
stem cell fate commitment GO:0048865 5 0.801
endocardial cushion development GO:0003197 26 0.799
endocardium development GO:0003157 10 0.798
negative regulation of striated muscle cell apoptotic process GO:0010664 8 0.798
cell fate specification involved in pattern specification GO:0060573 11 0.796
Mouse Fly
cell type specific apoptotic process GO:0097285 268 0.796
regulation of myoblast differentiation GO:0045661 29 0.795
neural tube patterning GO:0021532 43 0.793
lens induction in camera type eye GO:0060235 7 0.793
regulation of forebrain neuron differentiation GO:2000977 2 0.793
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.790
neural precursor cell proliferation GO:0061351 121 0.790
Mouse
dopaminergic neuron differentiation GO:0071542 14 0.790
Mouse
tendon formation GO:0035992 4 0.789
negative regulation of cell fate specification GO:0009996 4 0.788
sertoli cell differentiation GO:0060008 18 0.786
forebrain anterior posterior pattern specification GO:0021797 5 0.784
locomotory behavior GO:0007626 195 0.781
hippocampus development GO:0021766 52 0.778
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.777
negative regulation of myeloid cell differentiation GO:0045638 38 0.774
bmp signaling pathway involved in mesodermal cell fate specification GO:0060803 1 0.773
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.772
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.772
blood vessel morphogenesis GO:0048514 285 0.771
regulation of neuron maturation GO:0014041 5 0.769
positive regulation of wound healing GO:0090303 17 0.768
photoreceptor cell differentiation GO:0046530 52 0.766
negative regulation of cell proliferation GO:0008285 296 0.765
positive regulation of neuroblast proliferation GO:0002052 19 0.765
neural tube formation GO:0001841 108 0.760
Mouse
hepaticobiliary system development GO:0061008 67 0.760
digestive tract development GO:0048565 190 0.759
Mouse Worm
metanephric nephron tubule development GO:0072234 16 0.759
pallium development GO:0021543 120 0.756
Mouse
synapse organization GO:0050808 125 0.755
regulation of vascular wound healing GO:0061043 2 0.753
regulation of mechanoreceptor differentiation GO:0045631 5 0.753
asymmetric neuroblast division GO:0055059 1 0.752
primary neural tube formation GO:0014020 95 0.751
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.750
axonogenesis involved in innervation GO:0060385 5 0.749
development of primary sexual characteristics GO:0045137 143 0.748
Mouse Worm
cardiac conduction system development GO:0003161 12 0.748
metanephric capsule specification GO:0072267 1 0.746
mesenchymal cell apoptotic process GO:0097152 14 0.742
cell differentiation involved in kidney development GO:0061005 33 0.741
Mouse
myoblast proliferation GO:0051450 11 0.738
positive regulation of axon extension GO:0045773 20 0.738
middle ear morphogenesis GO:0042474 23 0.737
cardiocyte differentiation GO:0035051 87 0.736
endothelium development GO:0003158 45 0.735
striated muscle cell proliferation GO:0014855 39 0.735
photoreceptor cell development GO:0042461 40 0.733
negative regulation of immature t cell proliferation GO:0033087 3 0.732
regulation of endodermal cell differentiation GO:1903224 2 0.731
brain morphogenesis GO:0048854 32 0.729
lung cell differentiation GO:0060479 30 0.728
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis GO:0060598 2 0.727
male gonad development GO:0008584 88 0.727
Mouse
positive regulation of kidney development GO:0090184 28 0.727
Mouse
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.726
metanephric dct cell differentiation GO:0072240 3 0.724
regulation of anterior head development GO:2000742 2 0.723
Mouse
bone morphogenesis GO:0060349 78 0.720
central nervous system neuron axonogenesis GO:0021955 28 0.716
positive regulation of cardioblast differentiation GO:0051891 3 0.715
spinal cord patterning GO:0021511 25 0.714
Mouse
metanephric tubule development GO:0072170 18 0.713
primitive streak formation GO:0090009 10 0.711
Mouse
establishment of neuroblast polarity GO:0045200 1 0.711
metencephalon development GO:0022037 89 0.711
Mouse
cochlea morphogenesis GO:0090103 22 0.709
positive regulation of macrophage colony stimulating factor production GO:1901258 1 0.708

Isl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org