Mus musculus

76 known processes

Isl2

insulin related protein 2 (islet 2)

(Aliases: 3110001N10Rik,MGC171130)

Isl2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 337 0.863
Mouse Fly
sensory organ morphogenesis GO:0090596 242 0.831
Mouse
camera type eye development GO:0043010 266 0.715
Mouse
chemotaxis GO:0006935 247 0.683
skeletal system development GO:0001501 356 0.634
Mouse
ear morphogenesis GO:0042471 118 0.577
diencephalon development GO:0021536 63 0.551
Mouse
limb morphogenesis GO:0035108 149 0.506
Mouse
urogenital system development GO:0001655 261 0.503
Mouse
hindbrain development GO:0030902 128 0.502
Mouse
neural tube development GO:0021915 160 0.480
Mouse
skeletal system morphogenesis GO:0048705 203 0.468
Mouse
spinal cord development GO:0021510 81 0.453
renal system development GO:0072001 225 0.447
Mouse
regulation of organ morphogenesis GO:2000027 144 0.442
Mouse
ear development GO:0043583 200 0.389
forebrain development GO:0030900 302 0.384
Mouse
cell fate commitment GO:0045165 210 0.374
embryonic organ morphogenesis GO:0048562 276 0.374
Mouse
axonogenesis GO:0007409 274 0.344
central nervous system neuron differentiation GO:0021953 162 0.333
neuron migration GO:0001764 122 0.333
Mouse
appendage morphogenesis GO:0035107 149 0.331
Mouse
inner ear morphogenesis GO:0042472 101 0.327
cellular amino acid metabolic process GO:0006520 103 0.327
regulation of neuron differentiation GO:0045664 281 0.322
tube closure GO:0060606 91 0.315
Mouse
spinal cord motor neuron differentiation GO:0021522 35 0.313
striated muscle tissue development GO:0014706 293 0.311
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.311
formation of primary germ layer GO:0001704 77 0.303
Mouse
cell differentiation in spinal cord GO:0021515 53 0.296
ectoderm formation GO:0001705 3 0.294
Mouse
neural tube closure GO:0001843 90 0.293
Mouse
skin development GO:0043588 220 0.292
Mouse
axon guidance GO:0007411 141 0.284
gastrulation GO:0007369 116 0.281
Mouse
gland development GO:0048732 330 0.279
Mouse Fly
epithelial tube formation GO:0072175 130 0.263
Mouse
central nervous system projection neuron axonogenesis GO:0021952 21 0.263
epithelial tube morphogenesis GO:0060562 303 0.261
Mouse
neural tube formation GO:0001841 108 0.256
Mouse
tumor necrosis factor production GO:0032640 50 0.248
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.248
retina morphogenesis in camera type eye GO:0060042 45 0.246
Mouse
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.233
primary neural tube formation GO:0014020 95 0.231
Mouse
sensory perception of sound GO:0007605 97 0.230
stem cell differentiation GO:0048863 268 0.217
Mouse
neuron fate specification GO:0048665 30 0.216
endocrine system development GO:0035270 98 0.215
Mouse
bmp signaling pathway GO:0030509 93 0.215
cellular amine metabolic process GO:0044106 44 0.214
positive regulation of neuron differentiation GO:0045666 141 0.209
neural retina development GO:0003407 41 0.208
Mouse
epidermis development GO:0008544 187 0.208
Mouse
negative regulation of nervous system development GO:0051961 156 0.206
leukocyte differentiation GO:0002521 342 0.205
histone modification GO:0016570 159 0.202
canonical wnt signaling pathway GO:0060070 130 0.201
Mouse
retina development in camera type eye GO:0060041 119 0.200
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.197
Mouse Fly
palate development GO:0060021 76 0.192
chromatin modification GO:0016568 187 0.189
blood vessel morphogenesis GO:0048514 285 0.189
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.189
cardiac septum development GO:0003279 59 0.187
Mouse
lateral geniculate nucleus development GO:0021771 1 0.187
cerebral cortex development GO:0021987 86 0.186
Mouse
positive regulation of dopamine secretion GO:0033603 2 0.186
mesenchymal cell differentiation GO:0048762 107 0.181
Mouse
amine metabolic process GO:0009308 45 0.177
motor neuron migration GO:0097475 4 0.175
Mouse
digestive tract morphogenesis GO:0048546 147 0.174
Mouse
cartilage development GO:0051216 140 0.173
negative regulation of action potential GO:0045759 1 0.170
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.165
cell maturation GO:0048469 127 0.165
Mouse
limbic system development GO:0021761 72 0.159
Mouse
regulation of heart contraction GO:0008016 77 0.158
cardiac chamber morphogenesis GO:0003206 93 0.155
Mouse
negative regulation of neuron differentiation GO:0045665 101 0.153
peptidyl amino acid modification GO:0018193 336 0.151
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.150
Zebrafish Mouse
synaptic transmission involved in micturition GO:0060084 3 0.149
mesoderm morphogenesis GO:0048332 64 0.146
muscle cell differentiation GO:0042692 261 0.146
Mouse Fly
central nervous system neuron axonogenesis GO:0021955 28 0.145
appendage development GO:0048736 166 0.144
Mouse
embryonic digit morphogenesis GO:0042733 56 0.144
central nervous system neuron development GO:0021954 67 0.144
Mouse
pancreatic pp cell fate commitment GO:0003329 2 0.142
sensory perception of mechanical stimulus GO:0050954 107 0.140
embryonic epithelial tube formation GO:0001838 130 0.140
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.140
embryonic skeletal system morphogenesis GO:0048704 91 0.139
Mouse
visceral motor neuron differentiation GO:0021524 3 0.138
kidney development GO:0001822 213 0.136
Mouse
b cell activation GO:0042113 161 0.134
segmentation GO:0035282 93 0.133
Mouse Fly
pituitary gland development GO:0021983 38 0.132
Mouse
cerebral cortex radially oriented cell migration GO:0021799 31 0.132
Mouse
sensory perception GO:0007600 245 0.131
mesoderm formation GO:0001707 62 0.131
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.131
stem cell development GO:0048864 219 0.130
Mouse
skeletal muscle organ development GO:0060538 163 0.130
neuron projection guidance GO:0097485 141 0.126
mesenchymal cell development GO:0014031 93 0.126
Mouse
embryonic limb morphogenesis GO:0030326 126 0.125
neural nucleus development GO:0048857 22 0.125
response to growth factor GO:0070848 198 0.122
molting cycle GO:0042303 90 0.119
Mouse
muscle tissue development GO:0060537 308 0.117
Mouse
endoderm development GO:0007492 45 0.115
Mouse
olfactory bulb development GO:0021772 30 0.113
Mouse
lymphocyte differentiation GO:0030098 242 0.113
regulation of cellular amino acid metabolic process GO:0006521 5 0.113
angiogenesis GO:0001525 201 0.113
Mouse
nerve development GO:0021675 67 0.112
Mouse
chromatin organization GO:0006325 206 0.112
ventricular cardiac muscle tissue development GO:0003229 38 0.111
Mouse
synaptic transmission GO:0007268 329 0.110
pancreatic a cell fate commitment GO:0003326 2 0.110
digestive system development GO:0055123 200 0.110
Zebrafish Mouse Worm
telencephalon development GO:0021537 186 0.110
Mouse
chondrocyte differentiation GO:0002062 72 0.109
tube formation GO:0035148 140 0.108
Mouse
embryonic skeletal system development GO:0048706 120 0.108
Mouse
positive regulation of nervous system development GO:0051962 221 0.108
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.107
Fly
olfactory lobe development GO:0021988 32 0.107
Mouse
skeletal muscle cell differentiation GO:0035914 66 0.106
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.106
positive regulation of cell development GO:0010720 237 0.105
myeloid cell differentiation GO:0030099 233 0.104
ovulation cycle GO:0042698 59 0.103
negative regulation of cell development GO:0010721 169 0.103
dendrite development GO:0016358 115 0.101
Fly
acetylcholine secretion neurotransmission GO:0014055 2 0.101
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.100
cardiac chamber development GO:0003205 108 0.100
Mouse
limb development GO:0060173 166 0.099
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.099
Mouse
stem cell maintenance GO:0019827 130 0.098
extracellular structure organization GO:0043062 148 0.098
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.096
covalent chromatin modification GO:0016569 163 0.095
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.094
cell adhesion GO:0007155 329 0.093
pancreatic pp cell differentiation GO:0003312 2 0.092
connective tissue development GO:0061448 179 0.092
mesoderm development GO:0007498 100 0.090
Mouse
cranial nerve development GO:0021545 41 0.090
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.090
negative regulation of wnt signaling pathway GO:0030178 73 0.089
Mouse
hair follicle development GO:0001942 85 0.089
Mouse
neuron apoptotic process GO:0051402 142 0.089
Mouse
muscle tissue morphogenesis GO:0060415 53 0.088
Mouse
epithelial cell development GO:0002064 159 0.088
regulation of neuron projection development GO:0010975 169 0.087
regulation of myeloid cell differentiation GO:0045637 96 0.086
cytokine production GO:0001816 319 0.086
Mouse
circadian sleep wake cycle rem sleep GO:0042747 1 0.085
neural crest cell differentiation GO:0014033 54 0.083
Mouse
mechanoreceptor differentiation GO:0042490 67 0.083
ion transmembrane transport GO:0034220 361 0.083
autonomic nervous system development GO:0048483 43 0.082
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.082
norepinephrine transport GO:0015874 2 0.082
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.081
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.081
male sex differentiation GO:0046661 109 0.081
Mouse
auditory receptor cell fate specification GO:0042667 1 0.080
renal tubule development GO:0061326 87 0.079
Mouse
peripheral nervous system neuron axonogenesis GO:0048936 3 0.079
Mouse
regulation of interleukin 6 production GO:0032675 55 0.079
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.079
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.078
acetate ester transport GO:1901374 2 0.077
ventral spinal cord interneuron differentiation GO:0021514 16 0.076
Mouse
hair cycle GO:0042633 90 0.076
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.076
action potential GO:0001508 78 0.076
uterine epithelium development GO:0035847 1 0.075
Mouse
homeostasis of number of cells GO:0048872 210 0.075
development of primary sexual characteristics GO:0045137 143 0.075
Mouse Worm
astrocyte fate commitment GO:0060018 4 0.075
development of primary male sexual characteristics GO:0046546 88 0.074
Mouse
cardiac septum morphogenesis GO:0060411 46 0.073
Mouse
mesenchyme development GO:0060485 152 0.073
Mouse
wnt signaling pathway GO:0016055 188 0.073
Mouse
regulation of cell motility GO:2000145 236 0.072
regulation of organelle organization GO:0033043 289 0.072
negative regulation of neuron death GO:1901215 98 0.072
Mouse
cell proliferation in hindbrain GO:0021534 10 0.072
odontogenesis GO:0042476 78 0.071
Mouse
female gonad development GO:0008585 71 0.071
Mouse
regulation of anterior head development GO:2000742 2 0.070
Mouse
development of primary female sexual characteristics GO:0046545 73 0.070
Mouse
oviduct development GO:0060066 3 0.070
Mouse
inner ear receptor cell differentiation GO:0060113 61 0.070
somatotropin secreting cell differentiation GO:0060126 4 0.069
gonad development GO:0008406 141 0.069
Mouse Worm
heart contraction GO:0060047 93 0.069
regulation of cell migration GO:0030334 219 0.068
somite development GO:0061053 81 0.068
Mouse
generation of ovulation cycle rhythm GO:0060112 1 0.066
extracellular matrix organization GO:0030198 147 0.066
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.065
Mouse
visual perception GO:0007601 52 0.065
ureteric bud morphogenesis GO:0060675 62 0.064
Mouse
regulation of embryonic development GO:0045995 71 0.064
Mouse
respiratory system development GO:0060541 190 0.064
medial motor column neuron differentiation GO:0021526 2 0.064
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.063
lens development in camera type eye GO:0002088 62 0.063
regulation of membrane potential GO:0042391 192 0.062
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.062
cerebellum development GO:0021549 77 0.062
Mouse
bone development GO:0060348 120 0.062
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.062
Fly
heart morphogenesis GO:0003007 178 0.061
Mouse
endocardial cushion morphogenesis GO:0003203 18 0.061
Mouse
histone acetylation GO:0016573 41 0.061
neuron death GO:0070997 154 0.061
Mouse
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.061
positive regulation of protein modification process GO:0031401 299 0.061
Mouse
collagen fibril organization GO:0030199 32 0.061
Mouse
regulation of neural precursor cell proliferation GO:2000177 70 0.060
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.060
Mouse
divalent inorganic cation transport GO:0072511 178 0.060
cerebellar purkinje cell differentiation GO:0021702 13 0.060
Mouse
membrane organization GO:0061024 245 0.059
negative regulation of immune system process GO:0002683 209 0.059
metencephalon development GO:0022037 89 0.059
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.059
Mouse
detection of external stimulus GO:0009581 61 0.059
endodermal cell fate specification GO:0001714 4 0.058
somitogenesis GO:0001756 69 0.058
Mouse
stem cell proliferation GO:0072089 117 0.058
forebrain regionalization GO:0021871 25 0.058
Mouse
detection of stimulus GO:0051606 84 0.058
negative regulation of myeloid cell differentiation GO:0045638 38 0.057
developmental cell growth GO:0048588 84 0.057
Zebrafish Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.057
myeloid leukocyte differentiation GO:0002573 119 0.056
germ cell development GO:0007281 185 0.056
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.056
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.056
trophectodermal cell differentiation GO:0001829 21 0.056
globus pallidus development GO:0021759 2 0.055
positive regulation of keratinocyte proliferation GO:0010838 4 0.055
pallium development GO:0021543 120 0.055
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.054
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.054
regulation of histone modification GO:0031056 56 0.054
blood vessel remodeling GO:0001974 33 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.054
thalamus development GO:0021794 11 0.054
forebrain neuron differentiation GO:0021879 52 0.054
Mouse
multicellular organism growth GO:0035264 161 0.053
cardiac muscle tissue development GO:0048738 130 0.053
Mouse
regulation of norepinephrine secretion GO:0014061 2 0.053
cerebellar cortex development GO:0021695 48 0.053
Mouse
regulation of cell adhesion GO:0030155 154 0.053
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.053
ventral spinal cord development GO:0021517 48 0.052
forebrain cell migration GO:0021885 58 0.052
Mouse
regulation of neuron death GO:1901214 134 0.052
Mouse
nuclear division GO:0000280 158 0.052
peptidyl tyrosine modification GO:0018212 145 0.052
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.052
Fly
outflow tract morphogenesis GO:0003151 53 0.051
Mouse
apoptotic signaling pathway GO:0097190 306 0.051
regulation of myeloid leukocyte differentiation GO:0002761 58 0.051
paramesonephric duct development GO:0061205 3 0.051
Mouse
forebrain neuron fate commitment GO:0021877 13 0.050
Mouse
bundle of his development GO:0003166 4 0.050
regulation of cell activation GO:0050865 289 0.050
neuron projection extension GO:1990138 64 0.050
Zebrafish Mouse
norepinephrine secretion GO:0048243 2 0.050
auditory receptor cell differentiation GO:0042491 37 0.050
cardiac ventricle development GO:0003231 83 0.049
Mouse
male gonad development GO:0008584 88 0.049
Mouse
developmental maturation GO:0021700 193 0.049
Mouse
pancreas development GO:0031016 57 0.049
Zebrafish Mouse
peptidyl lysine modification GO:0018205 77 0.049
photoreceptor cell differentiation GO:0046530 52 0.048
metanephros development GO:0001656 79 0.048
Mouse
regulation of response to wounding GO:1903034 189 0.048
Mouse
transmembrane transport GO:0055085 412 0.048
positive regulation of macrophage colony stimulating factor production GO:1901258 1 0.048
Mouse
forebrain generation of neurons GO:0021872 63 0.048
Mouse
cervix development GO:0060067 2 0.047
Mouse
regulation of cytokine production GO:0001817 266 0.047
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.047
blastocyst development GO:0001824 80 0.047
cellular response to external stimulus GO:0071496 88 0.047
notch signaling pathway GO:0007219 71 0.046
heart process GO:0003015 94 0.046
auditory receptor cell fate determination GO:0042668 3 0.046
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.046
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.046
cell fate specification GO:0001708 72 0.046
regulation of apoptotic signaling pathway GO:2001233 197 0.046
negative regulation of cell proliferation GO:0008285 296 0.045
lateral inhibition GO:0046331 1 0.045
hypothalamus development GO:0021854 16 0.045
morphogenesis of a branching structure GO:0001763 203 0.044
Mouse
regulation of cell cycle GO:0051726 281 0.044
female gamete generation GO:0007292 74 0.044
negative regulation of neuron apoptotic process GO:0043524 92 0.044
Mouse
ossification GO:0001503 216 0.044
peripheral nervous system development GO:0007422 53 0.044
Mouse
positive regulation of angiogenesis GO:0045766 46 0.044
Mouse
organelle fission GO:0048285 170 0.043
regulation of cell projection organization GO:0031344 206 0.043
circadian sleep wake cycle non rem sleep GO:0042748 2 0.043
maintenance of apical basal cell polarity GO:0035090 3 0.043
Mouse
regulation of interleukin 1 production GO:0032652 26 0.043
Mouse
learning or memory GO:0007611 148 0.043
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.043
macrophage colony stimulating factor production GO:0036301 1 0.042
Mouse
nephron development GO:0072006 109 0.042
Mouse
multi organism reproductive behavior GO:0044705 29 0.042
regulation of feeding behavior GO:0060259 3 0.042
visceral serous pericardium development GO:0061032 2 0.042
nephron tubule morphogenesis GO:0072078 68 0.042
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.041
Mouse
tendon cell differentiation GO:0035990 4 0.041
cranial nerve morphogenesis GO:0021602 26 0.041
neural crest cell development GO:0014032 48 0.041
Mouse
pigmentation GO:0043473 71 0.041
hindbrain morphogenesis GO:0021575 46 0.041
Mouse
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.041
divalent metal ion transport GO:0070838 172 0.040
leukocyte migration GO:0050900 124 0.040
aromatic compound catabolic process GO:0019439 286 0.040
female sex differentiation GO:0046660 84 0.040
Mouse
negative regulation of molecular function GO:0044092 258 0.039
Mouse Fly
positive regulation of anterior head development GO:2000744 2 0.039
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.039
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.039
Mouse
b cell differentiation GO:0030183 78 0.038
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.038
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.038
Mouse
retinal bipolar neuron differentiation GO:0060040 5 0.038
protein acylation GO:0043543 64 0.038
spinal cord motor neuron cell fate specification GO:0021520 13 0.038
endomembrane system organization GO:0010256 147 0.038
cellular component assembly involved in morphogenesis GO:0010927 139 0.037
genitalia development GO:0048806 37 0.037
Mouse
lateral motor column neuron migration GO:0097477 3 0.037
Mouse
determination of left right symmetry GO:0007368 80 0.037
spermatogenesis GO:0007283 284 0.037
regulation of neuron apoptotic process GO:0043523 122 0.036
Mouse
midbrain development GO:0030901 35 0.036
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.036
regulation of stem cell proliferation GO:0072091 78 0.036
hair cell differentiation GO:0035315 40 0.036
negative regulation of dna binding GO:0043392 20 0.036
Mouse
head morphogenesis GO:0060323 34 0.036
Worm
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.036
cerebral cortex cell migration GO:0021795 44 0.036
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.036
interleukin 1 beta production GO:0032611 30 0.036
Mouse
ventral spinal cord interneuron fate commitment GO:0060579 14 0.036
Mouse
organelle localization GO:0051640 179 0.036
oogenesis GO:0048477 56 0.036
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.035
organic hydroxy compound metabolic process GO:1901615 203 0.035
positive regulation of cell death GO:0010942 224 0.035
neural precursor cell proliferation GO:0061351 121 0.035
Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.035
branching morphogenesis of an epithelial tube GO:0048754 159 0.035
Mouse
body fluid secretion GO:0007589 53 0.035
hippocampus development GO:0021766 52 0.035
Mouse
regulation of transferase activity GO:0051338 263 0.035
positive regulation of mesonephros development GO:0061213 20 0.035
Mouse
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.035
regulation of heart morphogenesis GO:2000826 22 0.035
Mouse
sensory perception of light stimulus GO:0050953 54 0.035
embryonic eye morphogenesis GO:0048048 29 0.035
mitochondrion distribution GO:0048311 4 0.035
ras protein signal transduction GO:0007265 77 0.035
syncytium formation by plasma membrane fusion GO:0000768 42 0.035
mesenchyme morphogenesis GO:0072132 32 0.034
Mouse
endocrine pancreas development GO:0031018 29 0.034
regulation of leukocyte differentiation GO:1902105 159 0.034
deltoid tuberosity development GO:0035993 3 0.034
organ growth GO:0035265 117 0.034
Mouse
regulation of cell growth GO:0001558 91 0.034
Mouse
blastocyst formation GO:0001825 33 0.034
regulation of angiogenesis GO:0045765 81 0.034
Mouse
cognition GO:0050890 149 0.034
Mouse
kidney morphogenesis GO:0060993 83 0.033
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.033
Mouse
adult behavior GO:0030534 135 0.033
cation transmembrane transport GO:0098655 266 0.033
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.033
cell differentiation in hindbrain GO:0021533 24 0.033
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.033
endoderm formation GO:0001706 20 0.033
Mouse
membrane depolarization GO:0051899 64 0.033
regulation of morphogenesis of a branching structure GO:0060688 53 0.033
Mouse
neuromuscular process GO:0050905 99 0.033
cell proliferation in external granule layer GO:0021924 10 0.033
ameboidal type cell migration GO:0001667 128 0.033
Mouse
acetylcholine transport GO:0015870 2 0.032
mesodermal cell differentiation GO:0048333 22 0.032
placenta development GO:0001890 140 0.032
Mouse
myeloid cell homeostasis GO:0002262 114 0.032
positive regulation of cell cycle GO:0045787 92 0.032
spinal cord motor neuron migration GO:0097476 4 0.032
Mouse
cerebellar purkinje cell layer development GO:0021680 26 0.032
Mouse
positive regulation of cell motility GO:2000147 116 0.032
locomotory behavior GO:0007626 195 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
telencephalon regionalization GO:0021978 14 0.031
Mouse
bone morphogenesis GO:0060349 78 0.031
telencephalon cell migration GO:0022029 55 0.031
Mouse
regulation of action potential GO:0098900 4 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
positive regulation of kidney development GO:0090184 28 0.031
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
cellular response to lipid GO:0071396 145 0.031
sperm motility GO:0030317 47 0.031
adult locomotory behavior GO:0008344 91 0.031
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.031
cellular protein complex assembly GO:0043623 116 0.030
prostate gland morphogenesis GO:0060512 32 0.030
rhythmic process GO:0048511 174 0.030
regulation of muscle tissue development GO:1901861 97 0.030
cardiocyte differentiation GO:0035051 87 0.030
Mouse
prostate gland development GO:0030850 48 0.030
response to transforming growth factor beta GO:0071559 88 0.030
ureteric bud development GO:0001657 94 0.030
Mouse
sclerotome development GO:0061056 4 0.030
regulation of retina development in camera type eye GO:1902866 3 0.030
synapse organization GO:0050808 125 0.030
positive regulation of cell adhesion GO:0045785 80 0.030
cell proliferation involved in heart valve development GO:2000793 2 0.029
positive regulation of growth GO:0045927 104 0.029
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.029
Mouse
regulation of hydrolase activity GO:0051336 246 0.029
regulation of cellular response to growth factor stimulus GO:0090287 82 0.029
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.029
odontogenesis of dentin containing tooth GO:0042475 66 0.029
Mouse
mammary gland epithelium development GO:0061180 65 0.029
glandular epithelial cell differentiation GO:0002067 38 0.029
defense response to other organism GO:0098542 197 0.029
response to oxygen levels GO:0070482 62 0.029
cardiac atrium development GO:0003230 24 0.029
Mouse
multi organism behavior GO:0051705 62 0.028
interleukin 6 production GO:0032635 58 0.028
Mouse
epithelial cell proliferation GO:0050673 174 0.028
cell proliferation in forebrain GO:0021846 30 0.028
Mouse
epithelial cell differentiation involved in kidney development GO:0035850 23 0.028
Mouse
male gamete generation GO:0048232 285 0.028
regulation of chromosome organization GO:0033044 83 0.028
cation transport GO:0006812 399 0.028
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.028
neuroblast proliferation GO:0007405 49 0.028
respiratory gaseous exchange GO:0007585 43 0.028
negative regulation of cellular amine metabolic process GO:0033239 1 0.028
gliogenesis GO:0042063 141 0.028
cardiac cell fate determination GO:0060913 2 0.028
Mouse
myoblast differentiation GO:0045445 52 0.028
Mouse
cerebellar purkinje cell layer formation GO:0021694 13 0.027
Mouse
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.027
multi multicellular organism process GO:0044706 109 0.027
regulation of striated muscle cell differentiation GO:0051153 81 0.027
multicellular organismal homeostasis GO:0048871 164 0.027
Fly
nucleotide catabolic process GO:0009166 217 0.027
vestibulocochlear nerve development GO:0021562 7 0.027
regulation of ion transport GO:0043269 215 0.027
response to extracellular stimulus GO:0009991 127 0.027
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.027
mapk cascade GO:0000165 281 0.027
regulation of binding GO:0051098 111 0.027
Mouse
regulation of intracellular transport GO:0032386 159 0.027
embryonic heart tube morphogenesis GO:0003143 51 0.027
cardiac right ventricle formation GO:0003219 3 0.027
hematopoietic stem cell differentiation GO:0060218 8 0.027
nucleoside metabolic process GO:0009116 246 0.026
his purkinje system cell differentiation GO:0060932 2 0.026
regulation of chromatin organization GO:1902275 57 0.026
cerebellum morphogenesis GO:0021587 42 0.026
Mouse
sympathetic nervous system development GO:0048485 22 0.026
cell type specific apoptotic process GO:0097285 268 0.026
Mouse
regulation of neural retina development GO:0061074 3 0.026

Isl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.094
nervous system disease DOID:863 0 0.094
sensory system disease DOID:0050155 0 0.079
eye and adnexa disease DOID:1492 0 0.079
eye disease DOID:5614 0 0.052
retinal disease DOID:5679 0 0.044
retinal degeneration DOID:8466 0 0.044