Mus musculus

0 known processes

Lrrc68

leucine rich repeat containing 68

(Aliases: Gm158)

Lrrc68 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 220 0.105
ras protein signal transduction GO:0007265 77 0.097
cellular ketone metabolic process GO:0042180 84 0.091
purine nucleoside triphosphate catabolic process GO:0009146 203 0.080
organonitrogen compound catabolic process GO:1901565 264 0.075
regulation of cellular ketone metabolic process GO:0010565 66 0.071
glycosyl compound catabolic process GO:1901658 206 0.070
regulation of mapk cascade GO:0043408 248 0.069
organophosphate catabolic process GO:0046434 232 0.069
regulation of cellular amine metabolic process GO:0033238 20 0.068
purine nucleoside metabolic process GO:0042278 241 0.066
negative regulation of molecular function GO:0044092 258 0.066
purine nucleoside catabolic process GO:0006152 205 0.066
ribose phosphate metabolic process GO:0019693 291 0.063
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.060
purine ribonucleotide metabolic process GO:0009150 290 0.057
ribonucleoside triphosphate catabolic process GO:0009203 199 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
regulation of neuron projection development GO:0010975 169 0.056
lipid biosynthetic process GO:0008610 179 0.055
negative regulation of cellular protein metabolic process GO:0032269 247 0.054
response to organonitrogen compound GO:0010243 246 0.054
endocytosis GO:0006897 168 0.053
mapk cascade GO:0000165 281 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.051
nucleoside triphosphate metabolic process GO:0009141 230 0.051
purine ribonucleotide catabolic process GO:0009154 208 0.050
cellular amino acid metabolic process GO:0006520 103 0.050
nucleoside triphosphate catabolic process GO:0009143 205 0.048
oocyte axis specification GO:0007309 2 0.048
ribonucleotide metabolic process GO:0009259 291 0.048
aromatic compound catabolic process GO:0019439 286 0.048
negative regulation of phosphorus metabolic process GO:0010563 184 0.047
negative regulation of phosphate metabolic process GO:0045936 184 0.046
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
establishment of organelle localization GO:0051656 122 0.044
nucleoside catabolic process GO:0009164 206 0.044
purine ribonucleoside catabolic process GO:0046130 205 0.043
organelle localization GO:0051640 179 0.043
heterocycle catabolic process GO:0046700 280 0.043
purine nucleotide metabolic process GO:0006163 302 0.042
purine ribonucleoside metabolic process GO:0046128 241 0.042
positive regulation of hydrolase activity GO:0051345 148 0.041
cation transport GO:0006812 399 0.041
telencephalon development GO:0021537 186 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
nucleoside metabolic process GO:0009116 246 0.040
axonogenesis GO:0007409 274 0.040
regulation of protein localization GO:0032880 231 0.039
regulation of kinase activity GO:0043549 249 0.039
cellular lipid metabolic process GO:0044255 323 0.038
nucleoside phosphate catabolic process GO:1901292 222 0.038
male gamete generation GO:0048232 285 0.038
amine metabolic process GO:0009308 45 0.038
ribonucleoside catabolic process GO:0042454 206 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
small gtpase mediated signal transduction GO:0007264 97 0.037
transmembrane transport GO:0055085 412 0.036
protein localization to organelle GO:0033365 185 0.036
purine nucleoside triphosphate metabolic process GO:0009144 226 0.036
negative regulation of protein metabolic process GO:0051248 282 0.036
organic cyclic compound catabolic process GO:1901361 295 0.035
ion transmembrane transport GO:0034220 361 0.035
regulation of protein kinase activity GO:0045859 232 0.035
ribonucleoside metabolic process GO:0009119 245 0.035
positive regulation of cellular catabolic process GO:0031331 148 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.034
regulation of cardioblast differentiation GO:0051890 3 0.034
regulation of hydrolase activity GO:0051336 246 0.033
regulation of lipid metabolic process GO:0019216 118 0.033
negative regulation of cellular component organization GO:0051129 194 0.032
anion transport GO:0006820 177 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.032
cellular homeostasis GO:0019725 240 0.032
cellular amine metabolic process GO:0044106 44 0.031
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
regulation of cell projection organization GO:0031344 206 0.030
negative regulation of protein phosphorylation GO:0001933 126 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
regulation of cellular response to stress GO:0080135 159 0.030
purine containing compound catabolic process GO:0072523 213 0.030
forebrain development GO:0030900 302 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.029
immune effector process GO:0002252 321 0.029
establishment of vesicle localization GO:0051650 81 0.029
nucleotide metabolic process GO:0009117 332 0.029
membrane organization GO:0061024 245 0.029
neuron migration GO:0001764 122 0.029
cytoplasmic transport GO:0016482 234 0.028
regulation of neuron differentiation GO:0045664 281 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
nitrogen compound transport GO:0071705 271 0.028
negative regulation of nervous system development GO:0051961 156 0.028
protein localization to membrane GO:0072657 108 0.028
positive regulation of cell development GO:0010720 237 0.027
cellular response to hormone stimulus GO:0032870 150 0.027
negative regulation of synapse assembly GO:0051964 3 0.027
nucleotide catabolic process GO:0009166 217 0.027
spermatogenesis GO:0007283 284 0.027
sensory perception GO:0007600 245 0.026
response to peptide hormone GO:0043434 127 0.026
protein catabolic process GO:0030163 221 0.026
regulation of nucleoside metabolic process GO:0009118 130 0.026
negative regulation of protein modification process GO:0031400 163 0.026
rho protein signal transduction GO:0007266 32 0.026
multicellular organismal signaling GO:0035637 91 0.026
response to peptide GO:1901652 136 0.026
macromolecule catabolic process GO:0009057 281 0.025
transmission of nerve impulse GO:0019226 76 0.025
carbohydrate metabolic process GO:0005975 230 0.025
intracellular protein transport GO:0006886 204 0.025
gtp catabolic process GO:0006184 143 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
locomotory behavior GO:0007626 195 0.024
regulation of nucleotide metabolic process GO:0006140 169 0.024
positive regulation of protein modification process GO:0031401 299 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
monocarboxylic acid metabolic process GO:0032787 191 0.023
peptidyl amino acid modification GO:0018193 336 0.023
cellular response to organonitrogen compound GO:0071417 145 0.023
chemotaxis GO:0006935 247 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
positive regulation of cell death GO:0010942 224 0.023
carbohydrate derivative catabolic process GO:1901136 231 0.022
oxidation reduction process GO:0055114 342 0.022
positive regulation of nucleoside metabolic process GO:0045979 91 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
cognition GO:0050890 149 0.022
endomembrane system organization GO:0010256 147 0.022
cation transmembrane transport GO:0098655 266 0.022
regulation of feeding behavior GO:0060259 3 0.022
oocyte construction GO:0007308 2 0.021
ribonucleotide catabolic process GO:0009261 208 0.021
fatty acid metabolic process GO:0006631 121 0.021
compound eye development GO:0048749 1 0.021
dephosphorylation GO:0016311 129 0.021
cell fate commitment GO:0045165 210 0.021
synaptic transmission GO:0007268 329 0.021
regulation of secretion by cell GO:1903530 249 0.021
protein palmitoylation GO:0018345 14 0.021
glycosyl compound metabolic process GO:1901657 246 0.020
maintenance of location GO:0051235 89 0.020
carbohydrate homeostasis GO:0033500 128 0.020
ossification GO:0001503 216 0.020
respiratory system development GO:0060541 190 0.020
cellular response to peptide GO:1901653 92 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
regulation of map kinase activity GO:0043405 120 0.020
multicellular organism growth GO:0035264 161 0.020
retrograde transport endosome to golgi GO:0042147 2 0.020
regulation of system process GO:0044057 200 0.020
lateral inhibition GO:0046331 1 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
muscle tissue development GO:0060537 308 0.020
vesicle localization GO:0051648 86 0.019
regulation of transferase activity GO:0051338 263 0.019
glycoprotein metabolic process GO:0009100 116 0.019
positive regulation of neuron differentiation GO:0045666 141 0.019
multi multicellular organism process GO:0044706 109 0.019
response to insulin GO:0032868 100 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
atp metabolic process GO:0046034 75 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
glutamine family amino acid biosynthetic process GO:0009084 2 0.019
apoptotic signaling pathway GO:0097190 306 0.019
regulation of cell cycle GO:0051726 281 0.019
negative regulation of growth GO:0045926 99 0.019
plasma membrane organization GO:0007009 90 0.019
lymphocyte differentiation GO:0030098 242 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
purine containing compound metabolic process GO:0072521 311 0.019
myeloid cell differentiation GO:0030099 233 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
circulatory system process GO:0003013 197 0.019
organelle assembly GO:0070925 177 0.018
organic anion transport GO:0015711 137 0.018
glucose homeostasis GO:0042593 128 0.018
engulfment of apoptotic cell GO:0043652 3 0.018
nucleoside monophosphate catabolic process GO:0009125 59 0.018
homeostasis of number of cells GO:0048872 210 0.018
negative regulation of neuron differentiation GO:0045665 101 0.018
regulation of organelle organization GO:0033043 289 0.018
glycerolipid metabolic process GO:0046486 122 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
regulation of ossification GO:0030278 112 0.018
response to lipopolysaccharide GO:0032496 128 0.018
microtubule based process GO:0007017 236 0.018
regulation of nucleotide catabolic process GO:0030811 122 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
multicellular organismal homeostasis GO:0048871 164 0.018
cellular chemical homeostasis GO:0055082 215 0.018
connective tissue development GO:0061448 179 0.018
negative regulation of transferase activity GO:0051348 85 0.018
inorganic ion transmembrane transport GO:0098660 234 0.017
regulation of cell motility GO:2000145 236 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
regulation of ras protein signal transduction GO:0046578 114 0.017
protein localization to nucleus GO:0034504 121 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
wnt signaling pathway GO:0016055 188 0.017
camera type eye development GO:0043010 266 0.017
mitotic cell cycle GO:0000278 195 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
central nervous system neuron differentiation GO:0021953 162 0.016
learning or memory GO:0007611 148 0.016
regulation of membrane potential GO:0042391 192 0.016
cytokine production GO:0001816 319 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
regulation of homeostatic process GO:0032844 182 0.016
protein autophosphorylation GO:0046777 61 0.016
rab protein signal transduction GO:0032482 1 0.016
neurotransmitter transport GO:0006836 76 0.016
divalent inorganic cation transport GO:0072511 178 0.016
regionalization GO:0003002 337 0.016
regulation of actin filament based process GO:0032970 99 0.016
bone development GO:0060348 120 0.016
sequestering of metal ion GO:0051238 19 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
rap protein signal transduction GO:0032486 3 0.016
regulation of protein serine threonine kinase activity GO:0071900 157 0.015
neuron death GO:0070997 154 0.015
nuclear transport GO:0051169 139 0.015
skin development GO:0043588 220 0.015
positive regulation of mapk cascade GO:0043410 170 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
dendrite development GO:0016358 115 0.015
regulation of cell cycle process GO:0010564 160 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.015
positive regulation of nucleotide catabolic process GO:0030813 88 0.015
regulation of endocytosis GO:0030100 69 0.015
tissue homeostasis GO:0001894 115 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
cell type specific apoptotic process GO:0097285 268 0.015
negative regulation of kinase activity GO:0033673 81 0.015
leukocyte differentiation GO:0002521 342 0.015
cell adhesion GO:0007155 329 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
negative regulation of cell development GO:0010721 169 0.015
striated muscle tissue development GO:0014706 293 0.015
organic acid biosynthetic process GO:0016053 86 0.015
action potential GO:0001508 78 0.015
melanosome localization GO:0032400 12 0.015
actin filament organization GO:0007015 113 0.015
sensory perception of touch GO:0050975 2 0.015
cell substrate adhesion GO:0031589 130 0.015
regulation of cell activation GO:0050865 289 0.015
neuronal action potential GO:0019228 54 0.014
phagocytosis GO:0006909 66 0.014
protein ubiquitination GO:0016567 171 0.014
cellularization GO:0007349 1 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
receptor mediated endocytosis GO:0006898 51 0.014
rhythmic process GO:0048511 174 0.014
lung development GO:0030324 164 0.014
gland development GO:0048732 330 0.014
establishment or maintenance of cell polarity GO:0007163 86 0.014
membrane tubulation GO:0097320 4 0.014
cellular protein complex assembly GO:0043623 116 0.014
cell maturation GO:0048469 127 0.014
organic hydroxy compound transport GO:0015850 93 0.014
germ cell development GO:0007281 185 0.014
negative regulation of cell projection organization GO:0031345 56 0.014
olfactory learning GO:0008355 2 0.014
phospholipid metabolic process GO:0006644 87 0.014
regulation of cell migration GO:0030334 219 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
positive regulation of nervous system development GO:0051962 221 0.014
stem cell differentiation GO:0048863 268 0.014
cell growth GO:0016049 130 0.014
developmental maturation GO:0021700 193 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
anatomical structure homeostasis GO:0060249 145 0.014
regulation of cellular component size GO:0032535 121 0.013
cation homeostasis GO:0055080 212 0.013
skeletal system development GO:0001501 356 0.013
synaptic vesicle localization GO:0097479 59 0.013
mitotic cell cycle process GO:1903047 159 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
regulation of myeloid cell differentiation GO:0045637 96 0.013
sensory organ morphogenesis GO:0090596 242 0.013
negative regulation of cell fate specification GO:0009996 4 0.013
innate immune response GO:0045087 157 0.013
t cell activation GO:0042110 289 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
positive regulation of organelle organization GO:0010638 128 0.013
skeletal muscle organ development GO:0060538 163 0.013
regulation of neuron death GO:1901214 134 0.013
sensory perception of mechanical stimulus GO:0050954 107 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
blood circulation GO:0008015 195 0.013
placenta development GO:0001890 140 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
tissue remodeling GO:0048771 102 0.013
regulation of body fluid levels GO:0050878 162 0.013
cofactor metabolic process GO:0051186 80 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
metencephalon development GO:0022037 89 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
positive regulation of transferase activity GO:0051347 167 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
spermatid differentiation GO:0048515 115 0.012
hindbrain development GO:0030902 128 0.012
positive regulation of neuron projection development GO:0010976 79 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.012
protein import GO:0017038 101 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
cellular response to lipid GO:0071396 145 0.012
translation GO:0006412 93 0.012
mrna metabolic process GO:0016071 84 0.012
protein modification by small protein conjugation or removal GO:0070647 207 0.012
lipoprotein metabolic process GO:0042157 43 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of ion transport GO:0043269 215 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
stem cell development GO:0048864 219 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
monosaccharide metabolic process GO:0005996 106 0.012
neuromuscular process GO:0050905 99 0.012
vesicle organization GO:0016050 60 0.012
pallium development GO:0021543 120 0.012
regulation of anatomical structure size GO:0090066 178 0.012
intracellular mrna localization GO:0008298 4 0.012
respiratory tube development GO:0030323 167 0.012
autophagy GO:0006914 45 0.012
exocytosis GO:0006887 121 0.012
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
mitochondrion organization GO:0007005 134 0.012
regulation of protein complex assembly GO:0043254 83 0.012
regulation of cytokine production GO:0001817 266 0.012
nuclear import GO:0051170 95 0.012
response to extracellular stimulus GO:0009991 127 0.011
directional locomotion GO:0033058 3 0.011
learning GO:0007612 98 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
peptide transport GO:0015833 133 0.011
negative regulation of mapk cascade GO:0043409 65 0.011
synaptic vesicle transport GO:0048489 57 0.011
spermatid development GO:0007286 108 0.011
gtp metabolic process GO:0046039 144 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
cellular ion homeostasis GO:0006873 165 0.011
lipid localization GO:0010876 126 0.011
negative regulation of immune system process GO:0002683 209 0.011
skeletal system morphogenesis GO:0048705 203 0.011
sulfur compound metabolic process GO:0006790 100 0.011
g protein coupled receptor signaling pathway GO:0007186 243 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
cerebellum development GO:0021549 77 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
pharynx development GO:0060465 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
protein targeting GO:0006605 143 0.011
limb development GO:0060173 166 0.011
epidermis development GO:0008544 187 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
regulation of protein catabolic process GO:0042176 108 0.011
regulation of lipid biosynthetic process GO:0046890 54 0.011
endodermal cell fate specification GO:0001714 4 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
cellular response to acid chemical GO:0071229 68 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of cell growth GO:0001558 91 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
metal ion homeostasis GO:0055065 189 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
development of primary sexual characteristics GO:0045137 143 0.010
response to acid chemical GO:0001101 111 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
muscle system process GO:0003012 141 0.010
regulation of phospholipid biosynthetic process GO:0071071 3 0.010
morphogenesis of a branching structure GO:0001763 203 0.010
axon ensheathment GO:0008366 76 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
protein processing GO:0016485 163 0.010
cellular protein catabolic process GO:0044257 155 0.010
extracellular structure organization GO:0043062 148 0.010
embryonic placenta development GO:0001892 98 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
glycerolipid biosynthetic process GO:0045017 50 0.010
cardiac cell fate specification GO:0060912 2 0.010
organelle fission GO:0048285 170 0.010
stress activated mapk cascade GO:0051403 80 0.010
regulation of transmembrane transport GO:0034762 128 0.010
regulation of synaptic plasticity GO:0048167 87 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.010
positive regulation of proteolysis GO:0045862 85 0.010
phospholipid biosynthetic process GO:0008654 36 0.010
response to inorganic substance GO:0010035 96 0.010
carbohydrate transport GO:0008643 62 0.010
regulation of actin cytoskeleton organization GO:0032956 84 0.010
phosphatidic acid biosynthetic process GO:0006654 2 0.010
rna processing GO:0006396 105 0.010

Lrrc68 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.140
nervous system disease DOID:863 0 0.140
central nervous system disease DOID:331 0 0.025
neuromuscular disease DOID:440 0 0.018
neuropathy DOID:870 0 0.018
charcot marie tooth disease DOID:10595 0 0.016
musculoskeletal system disease DOID:17 0 0.015
brain disease DOID:936 0 0.011
disease of metabolism DOID:0014667 0 0.011
neurodegenerative disease DOID:1289 0 0.011
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011
inherited metabolic disorder DOID:655 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010