Mus musculus

0 known processes

Vps4a

vacuolar protein sorting 4a (yeast)

(Aliases: MGC11698,AW553189,4930589C15Rik,AI325971)

Vps4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribonucleoside triphosphate catabolic process GO:0009203 199 0.216
Yeast
cellular component assembly involved in morphogenesis GO:0010927 139 0.208
pigment accumulation GO:0043476 1 0.170
negative regulation of protein metabolic process GO:0051248 282 0.109
purine ribonucleotide metabolic process GO:0009150 290 0.089
Yeast
mitotic cell cycle GO:0000278 195 0.086
Human
ribose phosphate metabolic process GO:0019693 291 0.080
Yeast
membrane organization GO:0061024 245 0.076
Human Yeast Fly
chromatin modification GO:0016568 187 0.072
regulation of organelle organization GO:0033043 289 0.070
nucleoside phosphate catabolic process GO:1901292 222 0.069
Yeast
cell growth GO:0016049 130 0.069
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
Yeast
regulation of cellular amine metabolic process GO:0033238 20 0.067
regulation of cell growth GO:0001558 91 0.066
amine metabolic process GO:0009308 45 0.065
cilium assembly GO:0042384 81 0.062
cilium morphogenesis GO:0060271 102 0.060
cellular amine metabolic process GO:0044106 44 0.060
covalent chromatin modification GO:0016569 163 0.060
synaptic transmission GO:0007268 329 0.060
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.059
regulation of cell cycle GO:0051726 281 0.059
Human
endocytosis GO:0006897 168 0.059
Fly
nucleoside phosphate metabolic process GO:0006753 338 0.057
Yeast
negative regulation of phosphorus metabolic process GO:0010563 184 0.055
regulation of cellular amino acid metabolic process GO:0006521 5 0.053
establishment of melanosome localization GO:0032401 11 0.052
negative regulation of phosphate metabolic process GO:0045936 184 0.051
ras protein signal transduction GO:0007265 77 0.051
regulation of vesicle mediated transport GO:0060627 139 0.050
Human
organophosphate catabolic process GO:0046434 232 0.050
Yeast
small gtpase mediated signal transduction GO:0007264 97 0.050
microtubule based process GO:0007017 236 0.050
nucleotide metabolic process GO:0009117 332 0.048
Yeast
cytoplasmic transport GO:0016482 234 0.047
Yeast
cellular amino acid metabolic process GO:0006520 103 0.047
histone modification GO:0016570 159 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
heterocycle catabolic process GO:0046700 280 0.046
Yeast
pigmentation GO:0043473 71 0.045
purine nucleoside catabolic process GO:0006152 205 0.045
Yeast
nucleoside catabolic process GO:0009164 206 0.043
Yeast
positive regulation of cellular amine metabolic process GO:0033240 5 0.043
organelle localization GO:0051640 179 0.043
cation transport GO:0006812 399 0.042
Mouse
protein localization to membrane GO:0072657 108 0.041
nucleoside triphosphate catabolic process GO:0009143 205 0.041
Yeast
positive regulation of cell development GO:0010720 237 0.041
regulation of transferase activity GO:0051338 263 0.040
organelle fission GO:0048285 170 0.040
purine nucleoside metabolic process GO:0042278 241 0.039
Yeast
mitotic cell cycle process GO:1903047 159 0.039
Human
cellular nitrogen compound catabolic process GO:0044270 280 0.039
Yeast
protein localization to organelle GO:0033365 185 0.039
Yeast
negative regulation of cellular component organization GO:0051129 194 0.038
spermatogenesis GO:0007283 284 0.038
cellular ketone metabolic process GO:0042180 84 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
apoptotic signaling pathway GO:0097190 306 0.036
positive regulation of protein modification process GO:0031401 299 0.036
ribonucleoside metabolic process GO:0009119 245 0.035
Yeast
negative regulation of protein phosphorylation GO:0001933 126 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
peptidyl amino acid modification GO:0018193 336 0.035
cell type specific apoptotic process GO:0097285 268 0.035
positive regulation of nervous system development GO:0051962 221 0.035
cellular response to dna damage stimulus GO:0006974 207 0.035
vesicle localization GO:0051648 86 0.035
nucleoside metabolic process GO:0009116 246 0.034
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 220 0.034
Yeast
regulation of cell projection organization GO:0031344 206 0.033
regulation of neuron differentiation GO:0045664 281 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
regulation of secretion by cell GO:1903530 249 0.032
Human
dephosphorylation GO:0016311 129 0.032
inclusion body assembly GO:0070841 3 0.032
synapse organization GO:0050808 125 0.031
axonogenesis GO:0007409 274 0.031
chromatin organization GO:0006325 206 0.031
negative regulation of synapse assembly GO:0051964 3 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
Yeast
negative regulation of molecular function GO:0044092 258 0.031
aromatic compound catabolic process GO:0019439 286 0.031
Yeast
ribonucleoside catabolic process GO:0042454 206 0.030
Yeast
regulation of intracellular transport GO:0032386 159 0.030
glycosyl compound metabolic process GO:1901657 246 0.029
Yeast
vesicle organization GO:0016050 60 0.029
Human Yeast
negative regulation of protein modification process GO:0031400 163 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
Yeast
male gamete generation GO:0048232 285 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
Yeast
regulation of chromosome organization GO:0033044 83 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
Yeast
positive regulation of organelle organization GO:0010638 128 0.028
microtubule based movement GO:0007018 84 0.028
protein refolding GO:0042026 1 0.027
purine containing compound metabolic process GO:0072521 311 0.027
Yeast
retrograde transport endosome to golgi GO:0042147 2 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
Yeast
developmental maturation GO:0021700 193 0.027
regulation of protein localization GO:0032880 231 0.027
organonitrogen compound catabolic process GO:1901565 264 0.026
Yeast
endomembrane system organization GO:0010256 147 0.026
Mouse
positive regulation of programmed cell death GO:0043068 218 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
Human Fly
cell division GO:0051301 120 0.025
Human
positive regulation of neuron differentiation GO:0045666 141 0.025
nucleotide catabolic process GO:0009166 217 0.024
Yeast
organic cyclic compound catabolic process GO:1901361 295 0.024
Yeast
camera type eye development GO:0043010 266 0.024
neurotransmitter secretion GO:0007269 62 0.024
dna repair GO:0006281 107 0.024
rab protein signal transduction GO:0032482 1 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
Yeast
protein acylation GO:0043543 64 0.024
positive regulation of neuron projection development GO:0010976 79 0.023
establishment of organelle localization GO:0051656 122 0.023
melanosome transport GO:0032402 11 0.023
negative regulation of cell cycle phase transition GO:1901988 48 0.023
Human
posttranscriptional regulation of gene expression GO:0010608 155 0.023
organelle assembly GO:0070925 177 0.023
regulation of neurotransmitter transport GO:0051588 35 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
negative regulation of cell cycle GO:0045786 123 0.022
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
Yeast
gtp catabolic process GO:0006184 143 0.022
purine containing compound catabolic process GO:0072523 213 0.022
Yeast
ribonucleotide catabolic process GO:0009261 208 0.021
Yeast
dna metabolic process GO:0006259 303 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.021
Yeast
intracellular protein transport GO:0006886 204 0.021
positive regulation of cell death GO:0010942 224 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.021
formation of organ boundary GO:0010160 1 0.021
multicellular organism growth GO:0035264 161 0.021
early endosome to late endosome transport GO:0045022 2 0.021
germ cell development GO:0007281 185 0.021
melanosome organization GO:0032438 8 0.021
negative regulation of growth GO:0045926 99 0.020
Fly
microtubule cytoskeleton organization GO:0000226 157 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
Yeast
exocytosis GO:0006887 121 0.020
Human
cytoskeleton dependent intracellular transport GO:0030705 50 0.020
regulation of protein transport GO:0051223 163 0.020
nuclear division GO:0000280 158 0.020
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
meiotic nuclear division GO:0007126 115 0.020
cation transmembrane transport GO:0098655 266 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
postsynaptic membrane organization GO:0001941 18 0.019
mapk cascade GO:0000165 281 0.019
axon cargo transport GO:0008088 33 0.019
regulation of secretion GO:0051046 274 0.019
Human
nucleocytoplasmic transport GO:0006913 139 0.019
positive regulation of cell projection organization GO:0031346 95 0.019
oocyte construction GO:0007308 2 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
regulation of protein kinase activity GO:0045859 232 0.018
negative regulation of nervous system development GO:0051961 156 0.018
trivalent inorganic cation transport GO:0072512 5 0.018
canonical wnt signaling pathway GO:0060070 130 0.018
regulation of cell division GO:0051302 76 0.018
Human
nucleoside triphosphate metabolic process GO:0009141 230 0.018
Yeast
positive regulation of apoptotic process GO:0043065 217 0.018
transmission of nerve impulse GO:0019226 76 0.018
gtp metabolic process GO:0046039 144 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.018
Human
transmembrane transport GO:0055085 412 0.018
regulation of exocytosis GO:0017157 61 0.018
Human
guanosine containing compound metabolic process GO:1901068 144 0.017
protein localization to plasma membrane GO:0072659 57 0.017
muscle tissue development GO:0060537 308 0.017
regulation of mitotic cell cycle GO:0007346 126 0.017
Human
intrinsic apoptotic signaling pathway GO:0097193 132 0.017
cell cycle checkpoint GO:0000075 47 0.017
Human
purine nucleotide catabolic process GO:0006195 211 0.017
Yeast
striated muscle tissue development GO:0014706 293 0.017
anatomical structure homeostasis GO:0060249 145 0.017
actin cytoskeleton organization GO:0030036 220 0.017
Fly
regulation of cell cycle phase transition GO:1901987 77 0.017
Human
regulation of kinase activity GO:0043549 249 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
Yeast
mitotic nuclear division GO:0007067 48 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
pigment granule localization GO:0051875 13 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
Yeast
cell maturation GO:0048469 127 0.016
positive regulation of transferase activity GO:0051347 167 0.016
regulation of map kinase activity GO:0043405 120 0.016
oocyte axis specification GO:0007309 2 0.016
regulation of mapk cascade GO:0043408 248 0.016
fat cell differentiation GO:0045444 160 0.016
plasma membrane organization GO:0007009 90 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
positive regulation of nuclear division GO:0051785 27 0.016
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.016
response to radiation GO:0009314 165 0.016
cellular lipid metabolic process GO:0044255 323 0.016
protein ubiquitination GO:0016567 171 0.015
renal system development GO:0072001 225 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
regulation of synaptic vesicle priming GO:0010807 4 0.015
macromolecule methylation GO:0043414 120 0.015
regulation of synaptic plasticity GO:0048167 87 0.015
response to insulin GO:0032868 100 0.015
nuclear transport GO:0051169 139 0.015
regulation of neuron death GO:1901214 134 0.015
regulation of cellular protein catabolic process GO:1903362 61 0.015
regulation of endocytic recycling GO:2001135 3 0.015
cardiac muscle tissue development GO:0048738 130 0.015
positive regulation of cellular protein catabolic process GO:1903364 34 0.015
cardiac chamber development GO:0003205 108 0.015
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
meiotic cell cycle GO:0051321 122 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.014
positive regulation of cell growth GO:0030307 33 0.014
intracellular mrna localization GO:0008298 4 0.014
intra golgi vesicle mediated transport GO:0006891 1 0.014
positive regulation of growth GO:0045927 104 0.014
locomotory behavior GO:0007626 195 0.014
sensory system development GO:0048880 3 0.014
methylation GO:0032259 134 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
protein catabolic process GO:0030163 221 0.014
Human Fly
regulation of cytoplasmic transport GO:1903649 112 0.014
melanosome localization GO:0032400 12 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
regulation of protein catabolic process GO:0042176 108 0.014
wnt signaling pathway GO:0016055 188 0.014
regulation of chromatin organization GO:1902275 57 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
Human
positive regulation of cell activation GO:0050867 158 0.013
establishment of pigment granule localization GO:0051905 12 0.013
cellular response to biotic stimulus GO:0071216 92 0.013
regulation of anatomical structure size GO:0090066 178 0.013
innate immune response GO:0045087 157 0.013
regulation of neurotransmitter levels GO:0001505 87 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
neuronal action potential GO:0019228 54 0.013
regulation of androgen receptor signaling pathway GO:0060765 3 0.013
trabecula formation GO:0060343 24 0.013
carbohydrate metabolic process GO:0005975 230 0.013
histone h4 k16 acetylation GO:0043984 3 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
protein secretion GO:0009306 111 0.013
synaptic vesicle localization GO:0097479 59 0.013
establishment of vesicle localization GO:0051650 81 0.013
lipoprotein biosynthetic process GO:0042158 33 0.013
g1 s transition of mitotic cell cycle GO:0000082 57 0.013
neuron death GO:0070997 154 0.013
asymmetric stem cell division GO:0098722 3 0.013
protein modification by small protein conjugation or removal GO:0070647 207 0.013
regulation of hydrolase activity GO:0051336 246 0.013
rho protein signal transduction GO:0007266 32 0.013
cell cycle g1 s phase transition GO:0044843 57 0.013
receptor mediated endocytosis GO:0006898 51 0.013
regulation of neuron projection development GO:0010975 169 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
extracellular matrix organization GO:0030198 147 0.013
lipid biosynthetic process GO:0008610 179 0.013
cell fate determination involved in pattern specification GO:0060582 1 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of proteolysis GO:0030162 164 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
regulation of histone modification GO:0031056 56 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
protein localization to nucleus GO:0034504 121 0.012
regulation of axon extension GO:0030516 43 0.012
spermatid development GO:0007286 108 0.012
response to organonitrogen compound GO:0010243 246 0.012
developmental growth involved in morphogenesis GO:0060560 138 0.012
cellular homeostasis GO:0019725 240 0.012
cell junction maintenance GO:0034331 4 0.012
asymmetric neuroblast division GO:0055059 1 0.012
dna recombination GO:0006310 92 0.012
activation of adenylate cyclase activity GO:0007190 4 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
positive regulation of kinase activity GO:0033674 155 0.012
regulation of cytokine production GO:0001817 266 0.012
pole plasm assembly GO:0007315 2 0.012
positive regulation of binding GO:0051099 49 0.012
developmental cell growth GO:0048588 84 0.012
substantia nigra development GO:0021762 2 0.012
establishment or maintenance of cell polarity GO:0007163 86 0.012
Fly
regulation of intracellular protein transport GO:0033157 82 0.012
maintenance of location GO:0051235 89 0.012
Yeast
regulation of extent of cell growth GO:0061387 52 0.012
mitochondrion organization GO:0007005 134 0.012
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.011
cardiac ventricle development GO:0003231 83 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
phospholipid metabolic process GO:0006644 87 0.011
interleukin 8 production GO:0032637 4 0.011
negative regulation of chromatin modification GO:1903309 19 0.011
response to metal ion GO:0010038 47 0.011
neurotransmitter transport GO:0006836 76 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
regulation of neurotransmitter secretion GO:0046928 29 0.011
lateral line system development GO:0048925 1 0.011
synaptic vesicle transport GO:0048489 57 0.011
centrosome separation GO:0051299 4 0.011
positive regulation of axon extension GO:0045773 20 0.011
establishment of synaptic vesicle localization GO:0097480 57 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
response to light stimulus GO:0009416 135 0.011
placenta development GO:0001890 140 0.011
negative regulation of organelle organization GO:0010639 90 0.011
regionalization GO:0003002 337 0.011
heart morphogenesis GO:0003007 178 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.011
response to inorganic substance GO:0010035 96 0.011
habituation GO:0046959 3 0.011
cellularization GO:0007349 1 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
nitrogen compound transport GO:0071705 271 0.011
multicellular organismal signaling GO:0035637 91 0.011
positive regulation of dna templated transcription elongation GO:0032786 2 0.011
regulation of cellular component size GO:0032535 121 0.011
urogenital system development GO:0001655 261 0.011
gene silencing GO:0016458 38 0.011
protein deubiquitination GO:0016579 19 0.011
mitochondrion degradation GO:0000422 3 0.011
inorganic ion transmembrane transport GO:0098660 234 0.010
synaptic vesicle priming GO:0016082 8 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
negative regulation of cell development GO:0010721 169 0.010
compound eye development GO:0048749 1 0.010
regulation of protein binding GO:0043393 60 0.010
positive regulation of nucleotide catabolic process GO:0030813 88 0.010
peptidyl serine modification GO:0018209 83 0.010
regulation of stress activated mapk cascade GO:0032872 69 0.010
positive regulation of cell cycle GO:0045787 92 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.010
macromolecule catabolic process GO:0009057 281 0.010
Human Fly
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
axoneme assembly GO:0035082 15 0.010
regulation of protein complex assembly GO:0043254 83 0.010

Vps4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
physical disorder DOID:0080015 0 0.012
congenital nervous system abnormality DOID:2490 0 0.012
immune system disease DOID:2914 0 0.011