Mus musculus

44 known processes

Alox5

arachidonate 5-lipoxygenase

(Aliases: 5LX,5-LO,AI850497,5LO,F730011J02,5-LOX)

Alox5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leukotriene production involved in inflammatory response GO:0002540 2 0.941
fatty acid derivative biosynthetic process GO:1901570 15 0.931
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.888
fatty acid biosynthetic process GO:0006633 41 0.871
unsaturated fatty acid metabolic process GO:0033559 31 0.831
store operated calcium entry GO:0002115 7 0.814
organic acid biosynthetic process GO:0016053 86 0.770
leukotriene biosynthetic process GO:0019370 5 0.660
icosanoid metabolic process GO:0006690 33 0.647
unsaturated fatty acid biosynthetic process GO:0006636 15 0.639
cellular lipid metabolic process GO:0044255 323 0.539
monocarboxylic acid metabolic process GO:0032787 191 0.496
lipid biosynthetic process GO:0008610 179 0.452
fatty acid derivative metabolic process GO:1901568 33 0.376
monocarboxylic acid biosynthetic process GO:0072330 61 0.361
fatty acid metabolic process GO:0006631 121 0.342
inflammatory response GO:0006954 244 0.323
protein homotrimerization GO:0070207 4 0.299
cellular response to calcium ion GO:0071277 14 0.156
icosanoid biosynthetic process GO:0046456 15 0.149
divalent inorganic cation transport GO:0072511 178 0.134
divalent metal ion transport GO:0070838 172 0.132
immune effector process GO:0002252 321 0.130
calcium ion transport GO:0006816 159 0.119
cellular amino acid metabolic process GO:0006520 103 0.116
cytokine production GO:0001816 319 0.098
carboxylic acid biosynthetic process GO:0046394 86 0.092
amine metabolic process GO:0009308 45 0.084
cellular ketone metabolic process GO:0042180 84 0.078
regulation of leukocyte mediated immunity GO:0002703 104 0.076
cellular amine metabolic process GO:0044106 44 0.076
regulation of cell motility GO:2000145 236 0.069
leukocyte differentiation GO:0002521 342 0.067
regulation of cell activation GO:0050865 289 0.065
Mouse
cellular response to inorganic substance GO:0071241 37 0.063
response to calcium ion GO:0051592 20 0.063
response to metal ion GO:0010038 47 0.063
regulation of mapk cascade GO:0043408 248 0.055
protein oligomerization GO:0051259 67 0.053
response to inorganic substance GO:0010035 96 0.053
negative regulation of immune system process GO:0002683 209 0.051
Mouse
leukocyte mediated immunity GO:0002443 174 0.050
regulation of leukocyte differentiation GO:1902105 159 0.050
membrane organization GO:0061024 245 0.050
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.049
regulation of cellular amine metabolic process GO:0033238 20 0.048
regulation of cytokine production GO:0001817 266 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
regulation of response to wounding GO:1903034 189 0.046
Mouse
regulation of secretion GO:0051046 274 0.046
chemotaxis GO:0006935 247 0.044
regulation of calcium ion transport GO:0051924 69 0.043
heterocycle catabolic process GO:0046700 280 0.043
hematopoietic progenitor cell differentiation GO:0002244 143 0.041
regulation of defense response GO:0031347 233 0.041
positive regulation of calcium ion transport GO:0051928 27 0.041
cellular response to metal ion GO:0071248 31 0.040
cation transport GO:0006812 399 0.040
regulation of map kinase activity GO:0043405 120 0.039
lymphocyte mediated immunity GO:0002449 139 0.039
protein trimerization GO:0070206 13 0.038
aromatic compound catabolic process GO:0019439 286 0.038
defense response to other organism GO:0098542 197 0.038
positive regulation of cytokine production GO:0001819 174 0.037
positive regulation of immune effector process GO:0002699 107 0.037
regulation of organelle organization GO:0033043 289 0.036
Mouse
transmembrane transport GO:0055085 412 0.036
positive regulation of protein modification process GO:0031401 299 0.035
cell chemotaxis GO:0060326 81 0.035
g protein coupled receptor signaling pathway GO:0007186 243 0.035
mapk cascade GO:0000165 281 0.034
ribonucleoside metabolic process GO:0009119 245 0.034
lymphocyte differentiation GO:0030098 242 0.033
wound healing GO:0042060 157 0.033
Mouse
leukocyte migration GO:0050900 124 0.032
ras protein signal transduction GO:0007265 77 0.032
striated muscle tissue development GO:0014706 293 0.032
regulation of establishment of protein localization GO:0070201 181 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
production of molecular mediator of immune response GO:0002440 103 0.031
positive regulation of transferase activity GO:0051347 167 0.030
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.030
ion transmembrane transport GO:0034220 361 0.030
positive regulation of protein phosphorylation GO:0001934 242 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
regulation of vesicle mediated transport GO:0060627 139 0.029
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
gland development GO:0048732 330 0.029
cytokine secretion GO:0050663 72 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
regulation of neuron differentiation GO:0045664 281 0.029
leukocyte activation involved in immune response GO:0002366 126 0.028
peptidyl amino acid modification GO:0018193 336 0.028
ameboidal type cell migration GO:0001667 128 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
digestive system development GO:0055123 200 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
regulation of protein kinase activity GO:0045859 232 0.027
purine nucleotide metabolic process GO:0006163 302 0.026
regulation of cell cycle GO:0051726 281 0.026
macromolecule catabolic process GO:0009057 281 0.026
granulocyte migration GO:0097530 43 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
Mouse
regulation of t cell activation GO:0050863 170 0.025
cation homeostasis GO:0055080 212 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
positive regulation of leukocyte mediated immunity GO:0002705 70 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
positive regulation of apoptotic process GO:0043065 217 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
nucleoside catabolic process GO:0009164 206 0.025
positive regulation of leukocyte differentiation GO:1902107 86 0.025
prostaglandin metabolic process GO:0006693 11 0.025
anatomical structure homeostasis GO:0060249 145 0.025
protein ubiquitination GO:0016567 171 0.025
regulation of protein serine threonine kinase activity GO:0071900 157 0.025
regulation of anatomical structure size GO:0090066 178 0.024
Mouse Rat
sensory perception GO:0007600 245 0.024
Rat
cytoplasmic transport GO:0016482 234 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
negative regulation of phagocytosis GO:0050765 4 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
ribonucleoside triphosphate catabolic process GO:0009203 199 0.024
purine containing compound metabolic process GO:0072521 311 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
metal ion homeostasis GO:0055065 189 0.024
muscle tissue development GO:0060537 308 0.024
cellular homeostasis GO:0019725 240 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
cellular response to biotic stimulus GO:0071216 92 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
cation transmembrane transport GO:0098655 266 0.023
regulation of muscle tissue development GO:1901861 97 0.023
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.023
regulation of cell projection organization GO:0031344 206 0.022
cellular response to organonitrogen compound GO:0071417 145 0.022
exocytosis GO:0006887 121 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
angiogenesis GO:0001525 201 0.022
myeloid cell differentiation GO:0030099 233 0.022
organonitrogen compound catabolic process GO:1901565 264 0.022
fertilization GO:0009566 127 0.022
homeostasis of number of cells GO:0048872 210 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.021
glycosyl compound catabolic process GO:1901658 206 0.021
muscle cell development GO:0055001 133 0.021
regulation of nucleotide catabolic process GO:0030811 122 0.021
erk1 and erk2 cascade GO:0070371 77 0.021
protein catabolic process GO:0030163 221 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
nucleoside metabolic process GO:0009116 246 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
negative regulation of cell activation GO:0050866 111 0.021
Mouse
second messenger mediated signaling GO:0019932 73 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
positive regulation of protein secretion GO:0050714 52 0.021
response to growth factor GO:0070848 198 0.021
organonitrogen compound biosynthetic process GO:1901566 192 0.021
Mouse
phospholipid metabolic process GO:0006644 87 0.021
Mouse
interleukin 8 production GO:0032637 4 0.021
positive regulation of cellular catabolic process GO:0031331 148 0.020
protein modification by small protein conjugation GO:0032446 187 0.020
coagulation GO:0050817 78 0.020
Mouse
organophosphate catabolic process GO:0046434 232 0.020
nucleotide metabolic process GO:0009117 332 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
t cell activation GO:0042110 289 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
negative regulation of molecular function GO:0044092 258 0.019
positive regulation of cell activation GO:0050867 158 0.019
muscle system process GO:0003012 141 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
tissue homeostasis GO:0001894 115 0.019
synaptic transmission GO:0007268 329 0.019
positive regulation of protein kinase activity GO:0045860 144 0.019
single fertilization GO:0007338 82 0.019
regulation of homeostatic process GO:0032844 182 0.019
peptidyl tyrosine modification GO:0018212 145 0.019
t cell differentiation GO:0030217 174 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
positive regulation of cell death GO:0010942 224 0.019
alpha beta t cell activation GO:0046631 91 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
endocytosis GO:0006897 168 0.019
Mouse
cellular metal ion homeostasis GO:0006875 151 0.019
positive regulation of protein transport GO:0051222 93 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.018
Mouse
regulation of cellular catabolic process GO:0031329 242 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
actin cytoskeleton organization GO:0030036 220 0.018
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
anion transport GO:0006820 177 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of interleukin 6 production GO:0032675 55 0.018
nitrogen compound transport GO:0071705 271 0.018
negative regulation of lymphocyte activation GO:0051250 91 0.018
myeloid cell homeostasis GO:0002262 114 0.018
regulation of cytoplasmic transport GO:1903649 112 0.017
blood vessel morphogenesis GO:0048514 285 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
regulation of hydrolase activity GO:0051336 246 0.017
gastrulation GO:0007369 116 0.017
camera type eye development GO:0043010 266 0.017
cellular protein complex assembly GO:0043623 116 0.017
Mouse
negative regulation of immune effector process GO:0002698 55 0.017
protein homooligomerization GO:0051260 43 0.017
regulation of endocytosis GO:0030100 69 0.017
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
positive regulation of secretion GO:0051047 130 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
striated muscle cell development GO:0055002 125 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
glucose homeostasis GO:0042593 128 0.017
response to lipopolysaccharide GO:0032496 128 0.016
small molecule biosynthetic process GO:0044283 132 0.016
dna metabolic process GO:0006259 303 0.016
cell migration involved in gastrulation GO:0042074 13 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.016
positive regulation of nervous system development GO:0051962 221 0.016
nuclear division GO:0000280 158 0.016
regulation of engulfment of apoptotic cell GO:1901074 2 0.016
Mouse
cellular ion homeostasis GO:0006873 165 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
regulation of protein transport GO:0051223 163 0.016
positive regulation of kinase activity GO:0033674 155 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.016
regulation of t cell proliferation GO:0042129 92 0.016
skeletal system development GO:0001501 356 0.016
response to organonitrogen compound GO:0010243 246 0.016
regulation of interleukin 8 production GO:0032677 3 0.016
organic anion transport GO:0015711 137 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
intracellular protein transport GO:0006886 204 0.016
regulation of kinase activity GO:0043549 249 0.016
positive regulation of organelle organization GO:0010638 128 0.016
Mouse
immunoglobulin production GO:0002377 73 0.015
ribose phosphate metabolic process GO:0019693 291 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of chemokine production GO:0032642 30 0.015
urogenital system development GO:0001655 261 0.015
regulation of gtp catabolic process GO:0033124 113 0.015
forebrain development GO:0030900 302 0.015
organic hydroxy compound transport GO:0015850 93 0.015
endomembrane system organization GO:0010256 147 0.015
detection of molecule of bacterial origin GO:0032490 2 0.015
negative regulation of phosphate metabolic process GO:0045936 184 0.015
protein localization to organelle GO:0033365 185 0.015
cellular chemical homeostasis GO:0055082 215 0.015
regulation of body fluid levels GO:0050878 162 0.015
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.015
positive regulation of gtp catabolic process GO:0033126 85 0.015
myeloid leukocyte mediated immunity GO:0002444 42 0.015
regulation of binding GO:0051098 111 0.015
regulation of protein localization GO:0032880 231 0.015
purine containing compound catabolic process GO:0072523 213 0.015
axonogenesis GO:0007409 274 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of protein binding GO:0043393 60 0.014
innate immune response GO:0045087 157 0.014
b cell differentiation GO:0030183 78 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
interleukin 6 production GO:0032635 58 0.014
negative regulation of cytokine production GO:0001818 84 0.014
cytokine production involved in immune response GO:0002367 34 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
regulation of transferase activity GO:0051338 263 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
regulation of cellular response to stress GO:0080135 159 0.014
granulocyte chemotaxis GO:0071621 39 0.014
calcium ion homeostasis GO:0055074 127 0.014
regulation of hormone levels GO:0010817 211 0.014
immune response regulating signaling pathway GO:0002764 125 0.014
phagocytosis GO:0006909 66 0.014
Mouse
regulation of secretion by cell GO:1903530 249 0.014
regulation of transmembrane transport GO:0034762 128 0.014
digestive tract morphogenesis GO:0048546 147 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
negative regulation of growth GO:0045926 99 0.013
regulation of t cell differentiation GO:0045580 83 0.013
cell activation involved in immune response GO:0002263 126 0.013
cell type specific apoptotic process GO:0097285 268 0.013
regulation of cellular component size GO:0032535 121 0.013
Mouse
regulation of adaptive immune response GO:0002819 90 0.013
Mouse
regulation of membrane potential GO:0042391 192 0.013
regulation of nucleoside metabolic process GO:0009118 130 0.013
tissue remodeling GO:0048771 102 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of ras gtpase activity GO:0032318 88 0.013
positive regulation of nucleotide catabolic process GO:0030813 88 0.013
myeloid leukocyte migration GO:0097529 57 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
Mouse
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.013
alpha beta t cell differentiation GO:0046632 69 0.013
activation of immune response GO:0002253 138 0.013
regulation of cell division GO:0051302 76 0.013
positive regulation of tumor necrosis factor production GO:0032760 30 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
negative regulation of leukocyte mediated immunity GO:0002704 29 0.013
calcium mediated signaling GO:0019722 46 0.013
cardiac muscle tissue development GO:0048738 130 0.013
developmental growth involved in morphogenesis GO:0060560 138 0.012
thrombin receptor signaling pathway GO:0070493 2 0.012
rho protein signal transduction GO:0007266 32 0.012
gtp catabolic process GO:0006184 143 0.012
regulation of chemotaxis GO:0050920 53 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
apoptotic signaling pathway GO:0097190 306 0.012
regulation of actin filament based process GO:0032970 99 0.012
Mouse
positive regulation of interleukin 8 production GO:0032757 2 0.012
positive regulation of map kinase activity GO:0043406 84 0.012
steroid metabolic process GO:0008202 119 0.012
neutrophil migration GO:1990266 37 0.012
regulation of proteolysis GO:0030162 164 0.012
negative regulation of protein modification process GO:0031400 163 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
organelle assembly GO:0070925 177 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
regulation of myotube differentiation GO:0010830 62 0.012
adaptive immune response GO:0002250 155 0.012
Mouse
skeletal system morphogenesis GO:0048705 203 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
sequestering of metal ion GO:0051238 19 0.012
cytokine metabolic process GO:0042107 71 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
cell division GO:0051301 120 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
organelle fission GO:0048285 170 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
defense response to virus GO:0051607 68 0.012
regulation of phospholipase c activity GO:1900274 3 0.012
b cell activation GO:0042113 161 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
mitotic cell cycle GO:0000278 195 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
leukocyte chemotaxis GO:0030595 69 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
interleukin 8 secretion GO:0072606 3 0.012
hormone secretion GO:0046879 128 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
regulation of cell substrate adhesion GO:0010810 73 0.012
positive regulation of phagocytosis GO:0050766 26 0.012
neutrophil mediated immunity GO:0002446 19 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
lateral inhibition GO:0046331 1 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
myeloid leukocyte activation GO:0002274 83 0.011
negative regulation of cell cycle GO:0045786 123 0.011
positive regulation of gtpase activity GO:0043547 85 0.011
neuron death GO:0070997 154 0.011
regulation of neuron projection development GO:0010975 169 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
microtubule based process GO:0007017 236 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
positive regulation of lymphocyte differentiation GO:0045621 61 0.011
nuclear transport GO:0051169 139 0.011
protein processing GO:0016485 163 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
mesodermal cell migration GO:0008078 4 0.011
meiotic nuclear division GO:0007126 115 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
negative regulation of adaptive immune response GO:0002820 25 0.011
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.011
regulation of actin cytoskeleton organization GO:0032956 84 0.011
Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.011
learning or memory GO:0007611 148 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
protein polymerization GO:0051258 57 0.011
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.011
actin filament organization GO:0007015 113 0.011
Mouse
stem cell differentiation GO:0048863 268 0.011
regulation of multi organism process GO:0043900 111 0.011
regulation of ion transport GO:0043269 215 0.011
carboxylic acid transport GO:0046942 100 0.011
negative regulation of cell development GO:0010721 169 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
negative regulation of lymphocyte proliferation GO:0050672 45 0.011
myosin filament assembly GO:0031034 2 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of action potential GO:0098900 4 0.011
stress activated mapk cascade GO:0051403 80 0.011
interferon gamma production GO:0032609 67 0.011
mature dendritic cell differentiation GO:0097029 3 0.011
neutrophil chemotaxis GO:0030593 36 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.011
retrograde transport endosome to golgi GO:0042147 2 0.010
norepinephrine secretion GO:0048243 2 0.010
regulation of angiogenesis GO:0045765 81 0.010
regulation of immunoglobulin production GO:0002637 42 0.010
tumor necrosis factor production GO:0032640 50 0.010
t cell mediated immunity GO:0002456 50 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
cellular response to peptidoglycan GO:0071224 4 0.010
action potential GO:0001508 78 0.010
regulation of mast cell activation GO:0033003 21 0.010
negative regulation of nik nf kappab signaling GO:1901223 2 0.010
digestive tract development GO:0048565 190 0.010
glycoprotein biosynthetic process GO:0009101 89 0.010
response to molecule of bacterial origin GO:0002237 143 0.010
carbohydrate metabolic process GO:0005975 230 0.010
negative regulation of secretion by cell GO:1903531 54 0.010
negative regulation of response to wounding GO:1903035 77 0.010
Mouse
response to nutrient levels GO:0031667 109 0.010
Rat
sensory organ morphogenesis GO:0090596 242 0.010
regulation of erk1 and erk2 cascade GO:0070372 71 0.010
regulation of neuron death GO:1901214 134 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
negative regulation of homeostatic process GO:0032845 71 0.010
cellular response to lipid GO:0071396 145 0.010
cellular response to nutrient levels GO:0031669 64 0.010
respiratory tube development GO:0030323 167 0.010
hormone metabolic process GO:0042445 86 0.010
guanosine containing compound metabolic process GO:1901068 144 0.010
response to extracellular stimulus GO:0009991 127 0.010
Rat

Alox5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
vascular disease DOID:178 0 0.386
cardiovascular system disease DOID:1287 0 0.386
disease of anatomical entity DOID:7 0 0.386
artery disease DOID:0050828 0 0.316
cerebrovascular disease DOID:6713 0 0.035
disease of metabolism DOID:0014667 0 0.021
immune system disease DOID:2914 0 0.020
nervous system disease DOID:863 0 0.016
hematopoietic system disease DOID:74 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
inherited metabolic disorder DOID:655 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011
central nervous system disease DOID:331 0 0.011
sensory system disease DOID:0050155 0 0.010