Mus musculus

32 known processes

Rbx1

ring-box 1

(Aliases: AA517855,1500002P15Rik)

Rbx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.325
cellular protein catabolic process GO:0044257 155 0.307
cellular macromolecule catabolic process GO:0044265 206 0.226
macromolecule catabolic process GO:0009057 281 0.202
modification dependent protein catabolic process GO:0019941 133 0.197
protein modification by small protein conjugation or removal GO:0070647 207 0.145
protein modification by small protein conjugation GO:0032446 187 0.128
protein ubiquitination GO:0016567 171 0.127
proteasomal protein catabolic process GO:0010498 98 0.116
cellular response to dna damage stimulus GO:0006974 207 0.086
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.084
ubiquitin dependent protein catabolic process GO:0006511 129 0.083
protein catabolic process GO:0030163 221 0.081
dna repair GO:0006281 107 0.077
regulation of cellular amino acid metabolic process GO:0006521 5 0.075
cellular amino acid metabolic process GO:0006520 103 0.063
positive regulation of protein catabolic process GO:0045732 60 0.057
regulation of protein catabolic process GO:0042176 108 0.053
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
regulation of proteolysis GO:0030162 164 0.048
regulation of cellular amine metabolic process GO:0033238 20 0.048
modification dependent macromolecule catabolic process GO:0043632 133 0.044
positive regulation of protein phosphorylation GO:0001934 242 0.043
protein maturation GO:0051604 176 0.041
apoptotic signaling pathway GO:0097190 306 0.040
dna metabolic process GO:0006259 303 0.040
cellular ketone metabolic process GO:0042180 84 0.039
protein polyubiquitination GO:0000209 33 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
spermatogenesis GO:0007283 284 0.033
amine metabolic process GO:0009308 45 0.032
negative regulation of leukocyte differentiation GO:1902106 51 0.032
cation transport GO:0006812 399 0.031
regulation of mitotic cell cycle phase transition GO:1901990 73 0.031
positive regulation of protein modification process GO:0031401 299 0.031
cellular amine metabolic process GO:0044106 44 0.030
regulation of peptidase activity GO:0052547 96 0.030
negative regulation of cell cycle GO:0045786 123 0.030
regulation of protein kinase activity GO:0045859 232 0.030
peptidyl amino acid modification GO:0018193 336 0.029
regulation of cellular catabolic process GO:0031329 242 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.028
regulation of cell cycle GO:0051726 281 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
regulation of mitotic cell cycle GO:0007346 126 0.027
regulation of cell cycle process GO:0010564 160 0.027
nucleotide catabolic process GO:0009166 217 0.027
regulation of intracellular transport GO:0032386 159 0.027
mitotic cell cycle process GO:1903047 159 0.026
myeloid cell differentiation GO:0030099 233 0.026
mitotic cell cycle GO:0000278 195 0.025
organelle fission GO:0048285 170 0.025
protein processing GO:0016485 163 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.024
ion transmembrane transport GO:0034220 361 0.024
spermatid differentiation GO:0048515 115 0.024
myeloid leukocyte differentiation GO:0002573 119 0.023
aromatic compound catabolic process GO:0019439 286 0.023
positive regulation of hydrolase activity GO:0051345 148 0.022
cation transmembrane transport GO:0098655 266 0.022
stem cell differentiation GO:0048863 268 0.022
regulation of protein localization GO:0032880 231 0.021
microtubule cytoskeleton organization GO:0000226 157 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
mitochondrion organization GO:0007005 134 0.021
organophosphate catabolic process GO:0046434 232 0.021
regulation of cellular protein catabolic process GO:1903362 61 0.021
negative regulation of mitotic cell cycle GO:0045930 58 0.021
nuclear transport GO:0051169 139 0.020
fertilization GO:0009566 127 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
positive regulation of transferase activity GO:0051347 167 0.020
granulocyte differentiation GO:0030851 17 0.020
cell cycle checkpoint GO:0000075 47 0.019
transmembrane transport GO:0055085 412 0.019
nucleoside catabolic process GO:0009164 206 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
regulation of ion transport GO:0043269 215 0.019
protein import GO:0017038 101 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
dna integrity checkpoint GO:0031570 28 0.018
regulation of transmembrane transport GO:0034762 128 0.018
regulation of establishment of protein localization GO:0070201 181 0.018
positive regulation of apoptotic signaling pathway GO:2001235 95 0.018
protein localization to organelle GO:0033365 185 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
germ cell development GO:0007281 185 0.018
nucleotide metabolic process GO:0009117 332 0.018
negative regulation of cell cycle process GO:0010948 69 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
spermatid development GO:0007286 108 0.017
regulation of organelle organization GO:0033043 289 0.017
regulation of protein transport GO:0051223 163 0.017
male gamete generation GO:0048232 285 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
regulation of kinase activity GO:0043549 249 0.017
negative regulation of cell cycle phase transition GO:1901988 48 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
nuclear division GO:0000280 158 0.017
cytoplasmic transport GO:0016482 234 0.017
synaptic transmission GO:0007268 329 0.017
regulation of hydrolase activity GO:0051336 246 0.017
intracellular protein transport GO:0006886 204 0.016
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.016
regulation of proteasomal protein catabolic process GO:0061136 46 0.016
purine containing compound catabolic process GO:0072523 213 0.016
regulation of protein maturation GO:1903317 96 0.016
positive regulation of nervous system development GO:0051962 221 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
forebrain development GO:0030900 302 0.016
positive regulation of intracellular transport GO:0032388 70 0.016
nucleocytoplasmic transport GO:0006913 139 0.016
telencephalon development GO:0021537 186 0.016
positive regulation of proteolysis GO:0045862 85 0.016
actin filament organization GO:0007015 113 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
atp catabolic process GO:0006200 55 0.015
regulation of response to dna damage stimulus GO:2001020 34 0.015
nuclear import GO:0051170 95 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
nucleotide excision repair GO:0006289 13 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
stem cell maintenance GO:0019827 130 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
cell division GO:0051301 120 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
negative regulation of protein maturation GO:1903318 79 0.014
purine nucleotide catabolic process GO:0006195 211 0.014
sensory perception GO:0007600 245 0.014
regulation of myeloid cell differentiation GO:0045637 96 0.014
regulation of protein processing GO:0070613 96 0.014
leukocyte differentiation GO:0002521 342 0.014
lateral inhibition GO:0046331 1 0.014
regulation of transferase activity GO:0051338 263 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.014
stem cell development GO:0048864 219 0.014
negative regulation of immune system process GO:0002683 209 0.014
b cell activation GO:0042113 161 0.014
mitotic cell cycle checkpoint GO:0007093 31 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
mapk cascade GO:0000165 281 0.013
g1 s transition of mitotic cell cycle GO:0000082 57 0.013
maintenance of location GO:0051235 89 0.013
nucleoside triphosphate metabolic process GO:0009141 230 0.013
purine containing compound metabolic process GO:0072521 311 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
regulation of system process GO:0044057 200 0.013
positive regulation of protein transport GO:0051222 93 0.013
muscle tissue development GO:0060537 308 0.013
ossification GO:0001503 216 0.013
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 10 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
carbohydrate metabolic process GO:0005975 230 0.013
positive regulation of cytoplasmic transport GO:1903651 40 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
cell cycle g1 s phase transition GO:0044843 57 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
protein localization to nucleus GO:0034504 121 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.012
respiratory system development GO:0060541 190 0.012
rna interference GO:0016246 2 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of neuron differentiation GO:0045664 281 0.012
endocytosis GO:0006897 168 0.012
cellular response to peptide GO:1901653 92 0.012
protein import into nucleus GO:0006606 95 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
kidney development GO:0001822 213 0.012
negative regulation of proteolysis GO:0045861 74 0.012
regulation of cellular response to stress GO:0080135 159 0.012
nucleoside phosphate metabolic process GO:0006753 338 0.012
protein localization to membrane GO:0072657 108 0.012
meiotic cell cycle GO:0051321 122 0.012
positive regulation of cell death GO:0010942 224 0.012
negative regulation of myeloid cell differentiation GO:0045638 38 0.012
urogenital system development GO:0001655 261 0.012
regulation of cell cycle phase transition GO:1901987 77 0.012
lipid localization GO:0010876 126 0.012
positive regulation of kinase activity GO:0033674 155 0.012
regulation of cell cycle g1 s phase transition GO:1902806 35 0.012
chromatin organization GO:0006325 206 0.012
epithelial cell proliferation GO:0050673 174 0.012
reactive oxygen species metabolic process GO:0072593 84 0.011
dna damage checkpoint GO:0000077 26 0.011
protein dna complex subunit organization GO:0071824 28 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
nucleoside metabolic process GO:0009116 246 0.011
immune effector process GO:0002252 321 0.011
smoothened signaling pathway GO:0007224 105 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
regulation of body fluid levels GO:0050878 162 0.011
organelle localization GO:0051640 179 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
regulation of cell cycle checkpoint GO:1901976 9 0.011
striated muscle tissue development GO:0014706 293 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
positive regulation of cellular protein catabolic process GO:1903364 34 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
response to radiation GO:0009314 165 0.011
regulation of membrane potential GO:0042391 192 0.011
homeostasis of number of cells GO:0048872 210 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
negative regulation of cellular component organization GO:0051129 194 0.010
camera type eye development GO:0043010 266 0.010
purine ribonucleoside metabolic process GO:0046128 241 0.010
locomotory behavior GO:0007626 195 0.010
cellular response to lipid GO:0071396 145 0.010
regulation of nucleocytoplasmic transport GO:0046822 73 0.010
asymmetric stem cell division GO:0098722 3 0.010
multicellular organismal response to stress GO:0033555 62 0.010
response to acid chemical GO:0001101 111 0.010
cellular chemical homeostasis GO:0055082 215 0.010
response to peptide hormone GO:0043434 127 0.010
compound eye development GO:0048749 1 0.010
cellular homeostasis GO:0019725 240 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
gonad development GO:0008406 141 0.010
pharynx development GO:0060465 1 0.010
regulation of epithelial cell proliferation GO:0050678 141 0.010
blood circulation GO:0008015 195 0.010

Rbx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
kidney cancer DOID:263 0 0.018
urinary system cancer DOID:3996 0 0.018
renal cell carcinoma DOID:4450 0 0.018
renal carcinoma DOID:4451 0 0.018
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017