Mus musculus

0 known processes

Spin4

spindlin family, member 4

(Aliases: 9630042H07Rik)

Spin4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.081
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.080
cellular amino acid metabolic process GO:0006520 103 0.068
cellular ketone metabolic process GO:0042180 84 0.062
positive regulation of cellular amine metabolic process GO:0033240 5 0.062
regulation of cellular amino acid metabolic process GO:0006521 5 0.059
cellular amine metabolic process GO:0044106 44 0.057
morphogenesis of embryonic epithelium GO:0016331 159 0.055
placenta development GO:0001890 140 0.053
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.048
neural precursor cell proliferation GO:0061351 121 0.047
wnt signaling pathway GO:0016055 188 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
immune effector process GO:0002252 321 0.044
purine ribonucleoside catabolic process GO:0046130 205 0.043
morphogenesis of a branching epithelium GO:0061138 193 0.041
positive regulation of protein modification process GO:0031401 299 0.040
skeletal system development GO:0001501 356 0.039
t cell activation GO:0042110 289 0.038
heterocycle catabolic process GO:0046700 280 0.037
lymphocyte differentiation GO:0030098 242 0.037
intracellular protein transport GO:0006886 204 0.037
cellular response to lipid GO:0071396 145 0.037
hematopoietic progenitor cell differentiation GO:0002244 143 0.036
regulation of transferase activity GO:0051338 263 0.035
regulation of establishment of protein localization GO:0070201 181 0.035
regulation of kinase activity GO:0043549 249 0.034
regulation of lymphocyte activation GO:0051249 240 0.033
cytoplasmic transport GO:0016482 234 0.033
g protein coupled receptor signaling pathway GO:0007186 243 0.032
compound eye development GO:0048749 1 0.032
regulation of cell activation GO:0050865 289 0.032
regulation of cell cycle GO:0051726 281 0.032
regulation of cellular ketone metabolic process GO:0010565 66 0.032
cell fate commitment GO:0045165 210 0.031
forebrain development GO:0030900 302 0.031
protein maturation GO:0051604 176 0.031
cation transport GO:0006812 399 0.030
renal system development GO:0072001 225 0.030
leukocyte differentiation GO:0002521 342 0.030
negative regulation of molecular function GO:0044092 258 0.030
regulation of intracellular transport GO:0032386 159 0.029
asymmetric stem cell division GO:0098722 3 0.029
peptidyl amino acid modification GO:0018193 336 0.029
protein processing GO:0016485 163 0.029
positive regulation of nervous system development GO:0051962 221 0.029
regulation of body fluid levels GO:0050878 162 0.029
epithelial tube morphogenesis GO:0060562 303 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
fat cell differentiation GO:0045444 160 0.028
regulation of protein kinase activity GO:0045859 232 0.028
cellular response to acid chemical GO:0071229 68 0.028
myeloid cell differentiation GO:0030099 233 0.027
protein catabolic process GO:0030163 221 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
morphogenesis of a branching structure GO:0001763 203 0.027
regulation of cellular response to stress GO:0080135 159 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
tube formation GO:0035148 140 0.026
sensory perception GO:0007600 245 0.026
nucleotide metabolic process GO:0009117 332 0.026
nitrogen compound transport GO:0071705 271 0.026
stem cell proliferation GO:0072089 117 0.026
aromatic compound catabolic process GO:0019439 286 0.026
positive regulation of kinase activity GO:0033674 155 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
divalent metal ion transport GO:0070838 172 0.025
regulation of cytoplasmic transport GO:1903649 112 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
nuclear transport GO:0051169 139 0.025
stem cell differentiation GO:0048863 268 0.025
regulation of protein localization GO:0032880 231 0.025
membrane organization GO:0061024 245 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
apoptotic signaling pathway GO:0097190 306 0.024
protein localization to organelle GO:0033365 185 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
smoothened signaling pathway GO:0007224 105 0.024
establishment of protein localization to organelle GO:0072594 118 0.024
cell type specific apoptotic process GO:0097285 268 0.024
regulation of secretion GO:0051046 274 0.024
telencephalon development GO:0021537 186 0.024
asymmetric neuroblast division GO:0055059 1 0.023
kidney development GO:0001822 213 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
blood circulation GO:0008015 195 0.023
positive regulation of transferase activity GO:0051347 167 0.023
cell adhesion GO:0007155 329 0.023
t cell differentiation GO:0030217 174 0.023
regulation of organelle organization GO:0033043 289 0.023
cellular macromolecule catabolic process GO:0044265 206 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
organophosphate catabolic process GO:0046434 232 0.022
purine ribonucleotide catabolic process GO:0009154 208 0.022
embryonic placenta development GO:0001892 98 0.022
negative regulation of cellular component organization GO:0051129 194 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
negative regulation of protein modification process GO:0031400 163 0.022
positive regulation of mapk cascade GO:0043410 170 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.022
camera type eye development GO:0043010 266 0.021
microtubule based process GO:0007017 236 0.021
sequestering of calcium ion GO:0051208 18 0.021
circulatory system process GO:0003013 197 0.021
nucleoside metabolic process GO:0009116 246 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
response to acid chemical GO:0001101 111 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
skin development GO:0043588 220 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
small gtpase mediated signal transduction GO:0007264 97 0.020
regulation of ion transport GO:0043269 215 0.020
positive regulation of cell death GO:0010942 224 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
regulation of protein transport GO:0051223 163 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
transepithelial chloride transport GO:0030321 4 0.020
regulation of hydrolase activity GO:0051336 246 0.020
regulation of cytokine production GO:0001817 266 0.020
macromolecule catabolic process GO:0009057 281 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.019
sequestering of metal ion GO:0051238 19 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
cell division GO:0051301 120 0.019
maintenance of location GO:0051235 89 0.019
inflammatory response GO:0006954 244 0.019
purine containing compound catabolic process GO:0072523 213 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
protein targeting GO:0006605 143 0.019
nucleoside phosphate catabolic process GO:1901292 222 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
regulation of secretion by cell GO:1903530 249 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
lipid biosynthetic process GO:0008610 179 0.019
neural tube development GO:0021915 160 0.018
muscle cell differentiation GO:0042692 261 0.018
purine nucleoside metabolic process GO:0042278 241 0.018
cell activation involved in immune response GO:0002263 126 0.018
stem cell development GO:0048864 219 0.018
regulation of interleukin 8 production GO:0032677 3 0.018
regulation of response to wounding GO:1903034 189 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
dna metabolic process GO:0006259 303 0.018
mapk cascade GO:0000165 281 0.018
b cell activation GO:0042113 161 0.018
positive regulation of cell development GO:0010720 237 0.018
heart contraction GO:0060047 93 0.018
cytokine production GO:0001816 319 0.018
regulation of nucleotide metabolic process GO:0006140 169 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
ossification GO:0001503 216 0.018
regulation of neuron differentiation GO:0045664 281 0.017
ribonucleotide metabolic process GO:0009259 291 0.017
negative regulation of immune system process GO:0002683 209 0.017
regulation of mapk cascade GO:0043408 248 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
mitotic cell cycle GO:0000278 195 0.017
gland development GO:0048732 330 0.017
regulation of system process GO:0044057 200 0.017
calcium ion transport GO:0006816 159 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
pigmentation GO:0043473 71 0.017
cation transmembrane transport GO:0098655 266 0.017
extrinsic apoptotic signaling pathway GO:0097191 126 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.017
nucleoside catabolic process GO:0009164 206 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
striated muscle cell development GO:0055002 125 0.017
transmembrane transport GO:0055085 412 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of defense response GO:0031347 233 0.017
cartilage development GO:0051216 140 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
purine nucleotide catabolic process GO:0006195 211 0.016
leukocyte activation involved in immune response GO:0002366 126 0.016
epidermis development GO:0008544 187 0.016
regulation of proteolysis GO:0030162 164 0.016
response to growth factor GO:0070848 198 0.016
anion transport GO:0006820 177 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
negative regulation of cell cycle GO:0045786 123 0.016
positive regulation of cell activation GO:0050867 158 0.016
epithelial cell proliferation GO:0050673 174 0.016
nuclear import GO:0051170 95 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
nucleotide catabolic process GO:0009166 217 0.016
spermatogenesis GO:0007283 284 0.016
regulation of heart contraction GO:0008016 77 0.016
negative regulation of protein phosphorylation GO:0001933 126 0.016
development of primary sexual characteristics GO:0045137 143 0.016
cellular response to growth factor stimulus GO:0071363 197 0.016
purine containing compound metabolic process GO:0072521 311 0.015
extracellular structure organization GO:0043062 148 0.015
endocytosis GO:0006897 168 0.015
cell maturation GO:0048469 127 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
respiratory system development GO:0060541 190 0.015
negative regulation of cell proliferation GO:0008285 296 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
cell cell junction organization GO:0045216 72 0.015
muscle cell development GO:0055001 133 0.015
regulation of t cell activation GO:0050863 170 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
male gamete generation GO:0048232 285 0.015
cellular lipid metabolic process GO:0044255 323 0.015
protein modification by small protein conjugation or removal GO:0070647 207 0.015
female gonad development GO:0008585 71 0.015
chemotaxis GO:0006935 247 0.015
regulation of inflammatory response GO:0050727 147 0.015
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.015
skeletal system morphogenesis GO:0048705 203 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
chromatin organization GO:0006325 206 0.014
nucleoside triphosphate catabolic process GO:0009143 205 0.014
stem cell maintenance GO:0019827 130 0.014
negative regulation of apoptotic signaling pathway GO:2001234 104 0.014
leukocyte proliferation GO:0070661 172 0.014
bone development GO:0060348 120 0.014
development of primary female sexual characteristics GO:0046545 73 0.014
connective tissue development GO:0061448 179 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
positive regulation of interleukin 8 production GO:0032757 2 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
cell junction organization GO:0034330 77 0.014
extracellular matrix organization GO:0030198 147 0.014
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.014
regulation of endopeptidase activity GO:0052548 89 0.014
single organism nuclear import GO:1902593 95 0.014
hair follicle development GO:0001942 85 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
oxidation reduction process GO:0055114 342 0.014
divalent inorganic cation transport GO:0072511 178 0.014
protein localization to nucleus GO:0034504 121 0.014
gonad development GO:0008406 141 0.014
retina development in camera type eye GO:0060041 119 0.014
urogenital system development GO:0001655 261 0.014
primary neural tube formation GO:0014020 95 0.014
regulation of membrane potential GO:0042391 192 0.014
bmp signaling pathway GO:0030509 93 0.014
ras protein signal transduction GO:0007265 77 0.014
protein import GO:0017038 101 0.014
striated muscle tissue development GO:0014706 293 0.014
regulation of cell cycle process GO:0010564 160 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of cell migration GO:0030334 219 0.014
neural tube formation GO:0001841 108 0.014
regulation of homeostatic process GO:0032844 182 0.014
heart process GO:0003015 94 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
trunk segmentation GO:0035290 4 0.013
blood vessel morphogenesis GO:0048514 285 0.013
organelle localization GO:0051640 179 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
lung development GO:0030324 164 0.013
carbohydrate homeostasis GO:0033500 128 0.013
cerebral cortex development GO:0021987 86 0.013
cellular homeostasis GO:0019725 240 0.013
positive regulation of lymphocyte activation GO:0051251 140 0.013
homeostasis of number of cells GO:0048872 210 0.013
glycoprotein metabolic process GO:0009100 116 0.013
purine nucleoside triphosphate metabolic process GO:0009144 226 0.013
regulation of cell adhesion GO:0030155 154 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
heart morphogenesis GO:0003007 178 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
regionalization GO:0003002 337 0.013
somite development GO:0061053 81 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
organelle fission GO:0048285 170 0.013
oocyte construction GO:0007308 2 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
protein secretion GO:0009306 111 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
multi multicellular organism process GO:0044706 109 0.013
negative regulation of cell development GO:0010721 169 0.013
response to lipopolysaccharide GO:0032496 128 0.013
protein ubiquitination GO:0016567 171 0.013
hormone secretion GO:0046879 128 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
small molecule biosynthetic process GO:0044283 132 0.013
rho protein signal transduction GO:0007266 32 0.013
pallium development GO:0021543 120 0.013
axonogenesis GO:0007409 274 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
respiratory tube development GO:0030323 167 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
ureteric bud development GO:0001657 94 0.013
response to organonitrogen compound GO:0010243 246 0.013
regulation of cell motility GO:2000145 236 0.012
cation homeostasis GO:0055080 212 0.012
epithelial tube formation GO:0072175 130 0.012
protein import into nucleus GO:0006606 95 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
anatomical structure homeostasis GO:0060249 145 0.012
ion transmembrane transport GO:0034220 361 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
negative regulation of protein processing GO:0010955 79 0.012
positive regulation of defense response GO:0031349 124 0.012
inner ear receptor cell differentiation GO:0060113 61 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.012
tube closure GO:0060606 91 0.012
regulation of protein secretion GO:0050708 82 0.012
developmental maturation GO:0021700 193 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
positive regulation of vasoconstriction GO:0045907 4 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
cellular chemical homeostasis GO:0055082 215 0.012
sensory organ morphogenesis GO:0090596 242 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
midgut development GO:0007494 4 0.012
mature dendritic cell differentiation GO:0097029 3 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
muscle contraction GO:0006936 101 0.012
regulation of protein catabolic process GO:0042176 108 0.012
positive regulation of peptidase activity GO:0010952 49 0.012
alpha beta t cell activation GO:0046631 91 0.012
mesoderm development GO:0007498 100 0.012
regulation of anatomical structure size GO:0090066 178 0.012
cell proliferation in forebrain GO:0021846 30 0.012
neural tube closure GO:0001843 90 0.012
positive regulation of neuron differentiation GO:0045666 141 0.012
regulation of ossification GO:0030278 112 0.012
regulation of protein maturation GO:1903317 96 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.011
ear development GO:0043583 200 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.011
cellular ion homeostasis GO:0006873 165 0.011
olfactory bulb axon guidance GO:0071678 1 0.011
sulfur compound metabolic process GO:0006790 100 0.011
gtp catabolic process GO:0006184 143 0.011
lymphocyte proliferation GO:0046651 164 0.011
neuroblast proliferation GO:0007405 49 0.011
regulation of fat cell differentiation GO:0045598 81 0.011
oocyte axis specification GO:0007309 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
peptide transport GO:0015833 133 0.011
positive regulation of t cell activation GO:0050870 101 0.011
hemostasis GO:0007599 78 0.011
positive regulation of immune effector process GO:0002699 107 0.011
regulation of intracellular protein transport GO:0033157 82 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
alpha beta t cell differentiation GO:0046632 69 0.011
regulation of norepinephrine secretion GO:0014061 2 0.011
segmentation GO:0035282 93 0.011
negative regulation of cell activation GO:0050866 111 0.011
interleukin 8 production GO:0032637 4 0.011
olfactory learning GO:0008355 2 0.011
response to peptide hormone GO:0043434 127 0.011
regulation of tube size GO:0035150 57 0.011
response to vitamin d GO:0033280 3 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
tissue remodeling GO:0048771 102 0.011
negative regulation of nervous system development GO:0051961 156 0.011
fertilization GO:0009566 127 0.011
wound healing GO:0042060 157 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
metal ion homeostasis GO:0055065 189 0.011
fat soluble vitamin biosynthetic process GO:0042362 4 0.011
spermatid differentiation GO:0048515 115 0.011
rhythmic process GO:0048511 174 0.011
multicellular organismal signaling GO:0035637 91 0.011
regulation of hormone levels GO:0010817 211 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
palate development GO:0060021 76 0.011
regulation of cell projection organization GO:0031344 206 0.011
muscle tissue development GO:0060537 308 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
negative regulation of myeloid cell differentiation GO:0045638 38 0.011
appendage development GO:0048736 166 0.011
transmission of nerve impulse GO:0019226 76 0.011
cellular response to dna damage stimulus GO:0006974 207 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
carbohydrate transport GO:0008643 62 0.010
retrograde transport endosome to golgi GO:0042147 2 0.010
regulation of bmp signaling pathway GO:0030510 60 0.010
adaptive immune response GO:0002250 155 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
regulation of osteoblast differentiation GO:0045667 67 0.010
chondrocyte hypertrophy GO:0003415 4 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.010
regulation of multi organism process GO:0043900 111 0.010
central nervous system neuron differentiation GO:0021953 162 0.010
ubiquitin dependent protein catabolic process GO:0006511 129 0.010
mesonephric epithelium development GO:0072163 94 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
regulation of interleukin 8 secretion GO:2000482 2 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
mitotic cell cycle process GO:1903047 159 0.010
regulation of neural precursor cell proliferation GO:2000177 70 0.010
nuclear division GO:0000280 158 0.010
mesenchymal cell differentiation GO:0048762 107 0.010

Spin4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
immune system disease DOID:2914 0 0.015
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010