Mus musculus

68 known processes

G2e3

G2/M-phase specific E3 ubiquitin ligase

(Aliases: 9030416F18,D930034K21Rik,mKIAA1333,AW046379,6030408C04Rik)

G2e3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 206 0.463
organelle fission GO:0048285 170 0.146
cellular protein catabolic process GO:0044257 155 0.144
cellular ketone metabolic process GO:0042180 84 0.139
mitotic cell cycle process GO:1903047 159 0.136
ubiquitin dependent protein catabolic process GO:0006511 129 0.130
cellular nitrogen compound catabolic process GO:0044270 280 0.115
macromolecule catabolic process GO:0009057 281 0.109
aromatic compound catabolic process GO:0019439 286 0.100
regulation of cellular amine metabolic process GO:0033238 20 0.098
nucleoside metabolic process GO:0009116 246 0.093
cellular amine metabolic process GO:0044106 44 0.092
nucleoside catabolic process GO:0009164 206 0.090
regulation of nuclear division GO:0051783 56 0.089
ribonucleoside metabolic process GO:0009119 245 0.089
organic cyclic compound catabolic process GO:1901361 295 0.085
amine metabolic process GO:0009308 45 0.082
purine ribonucleotide metabolic process GO:0009150 290 0.077
negative regulation of cellular component organization GO:0051129 194 0.076
nucleobase containing small molecule metabolic process GO:0055086 352 0.075
regulation of cellular amino acid metabolic process GO:0006521 5 0.075
protein localization to organelle GO:0033365 185 0.073
organophosphate catabolic process GO:0046434 232 0.073
microtubule based process GO:0007017 236 0.070
ribose phosphate metabolic process GO:0019693 291 0.068
cell division GO:0051301 120 0.068
nucleotide metabolic process GO:0009117 332 0.068
ribonucleoside triphosphate catabolic process GO:0009203 199 0.066
mitotic cell cycle GO:0000278 195 0.065
purine nucleoside triphosphate catabolic process GO:0009146 203 0.063
ribonucleoside triphosphate metabolic process GO:0009199 220 0.063
organelle assembly GO:0070925 177 0.059
regulation of cell cycle GO:0051726 281 0.059
purine ribonucleoside catabolic process GO:0046130 205 0.058
meiotic cell cycle GO:0051321 122 0.057
purine nucleoside metabolic process GO:0042278 241 0.056
microtubule cytoskeleton organization GO:0000226 157 0.056
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.054
ribonucleoside catabolic process GO:0042454 206 0.054
carbohydrate derivative catabolic process GO:1901136 231 0.052
heterocycle catabolic process GO:0046700 280 0.051
modification dependent protein catabolic process GO:0019941 133 0.051
purine nucleoside catabolic process GO:0006152 205 0.050
regulation of organelle organization GO:0033043 289 0.049
organonitrogen compound catabolic process GO:1901565 264 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.049
regulation of microtubule based process GO:0032886 52 0.048
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
chromosome segregation GO:0007059 48 0.047
regulation of cell cycle process GO:0010564 160 0.046
nuclear division GO:0000280 158 0.045
chromatin modification GO:0016568 187 0.045
purine containing compound metabolic process GO:0072521 311 0.045
negative regulation of cell cycle GO:0045786 123 0.043
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
purine containing compound catabolic process GO:0072523 213 0.042
meiotic nuclear division GO:0007126 115 0.042
glycosyl compound metabolic process GO:1901657 246 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
regulation of membrane potential GO:0042391 192 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
negative regulation of cell cycle process GO:0010948 69 0.040
glycosyl compound catabolic process GO:1901658 206 0.040
cellular amino acid metabolic process GO:0006520 103 0.039
nucleoside monophosphate metabolic process GO:0009123 85 0.039
purine nucleotide metabolic process GO:0006163 302 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
nucleoside triphosphate catabolic process GO:0009143 205 0.037
ribonucleotide metabolic process GO:0009259 291 0.036
purine nucleotide catabolic process GO:0006195 211 0.036
meiotic cell cycle process GO:1903046 77 0.036
chromosome organization involved in meiosis GO:0070192 39 0.035
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.035
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.035
nucleotide catabolic process GO:0009166 217 0.035
germ cell development GO:0007281 185 0.034
protein modification by small protein conjugation or removal GO:0070647 207 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
heterochromatin organization GO:0070828 4 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.032
fat cell differentiation GO:0045444 160 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
regulation of cellular catabolic process GO:0031329 242 0.031
response to molecule of bacterial origin GO:0002237 143 0.030
ribonucleotide catabolic process GO:0009261 208 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
lateral inhibition GO:0046331 1 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
kinetochore organization GO:0051383 2 0.029
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
protein localization to nucleus GO:0034504 121 0.027
protein maturation GO:0051604 176 0.027
regulation of cell activation GO:0050865 289 0.027
mitotic sister chromatid segregation GO:0000070 14 0.027
small gtpase mediated signal transduction GO:0007264 97 0.026
leukocyte differentiation GO:0002521 342 0.026
sensory perception GO:0007600 245 0.026
immune effector process GO:0002252 321 0.026
skeletal system development GO:0001501 356 0.026
atp catabolic process GO:0006200 55 0.026
cellular response to lipid GO:0071396 145 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.024
oxidation reduction process GO:0055114 342 0.024
ossification GO:0001503 216 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
regulation of fat cell differentiation GO:0045598 81 0.023
centromere complex assembly GO:0034508 3 0.023
cytoplasmic transport GO:0016482 234 0.023
rho protein signal transduction GO:0007266 32 0.023
protein catabolic process GO:0030163 221 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.022
protein targeting GO:0006605 143 0.022
translation GO:0006412 93 0.022
mitotic nuclear division GO:0007067 48 0.022
attachment of spindle microtubules to kinetochore GO:0008608 4 0.022
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.021
learning or memory GO:0007611 148 0.021
regulation of protein maturation GO:1903317 96 0.021
regulation of transferase activity GO:0051338 263 0.021
positive regulation of organelle organization GO:0010638 128 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
development of primary sexual characteristics GO:0045137 143 0.020
negative regulation of molecular function GO:0044092 258 0.020
regulation of homeostatic process GO:0032844 182 0.020
protein import GO:0017038 101 0.020
regulation of meiotic cell cycle GO:0051445 34 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
negative regulation of organelle organization GO:0010639 90 0.020
regulation of intracellular transport GO:0032386 159 0.019
sister chromatid segregation GO:0000819 20 0.019
membrane organization GO:0061024 245 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
peptidyl amino acid modification GO:0018193 336 0.019
positive regulation of protein modification process GO:0031401 299 0.019
forebrain development GO:0030900 302 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
male gamete generation GO:0048232 285 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
telencephalon development GO:0021537 186 0.018
gonad development GO:0008406 141 0.018
cell type specific apoptotic process GO:0097285 268 0.018
apoptotic signaling pathway GO:0097190 306 0.018
ribonucleoside monophosphate metabolic process GO:0009161 80 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
intracellular protein transport GO:0006886 204 0.018
rna 3 end processing GO:0031123 20 0.018
response to light stimulus GO:0009416 135 0.017
blastocyst development GO:0001824 80 0.017
negative regulation of nuclear division GO:0051784 19 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.017
nuclear import GO:0051170 95 0.017
cellular chemical homeostasis GO:0055082 215 0.017
ras protein signal transduction GO:0007265 77 0.017
action potential GO:0001508 78 0.017
response to extracellular stimulus GO:0009991 127 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
negative regulation of chromatin silencing GO:0031936 1 0.017
negative regulation of protein processing GO:0010955 79 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
regulation of cytoplasmic mrna processing body assembly GO:0010603 2 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
epidermis development GO:0008544 187 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
single organism nuclear import GO:1902593 95 0.016
negative regulation of meiotic cell cycle GO:0051447 14 0.016
cellular homeostasis GO:0019725 240 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
inflammatory response GO:0006954 244 0.015
maintenance of location GO:0051235 89 0.015
nuclear transport GO:0051169 139 0.015
regulation of system process GO:0044057 200 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
regulation of cellular component biogenesis GO:0044087 181 0.015
cation transmembrane transport GO:0098655 266 0.015
positive regulation of lymphocyte activation GO:0051251 140 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
atp metabolic process GO:0046034 75 0.014
negative regulation of translation GO:0017148 22 0.014
protein processing GO:0016485 163 0.014
retina development in camera type eye GO:0060041 119 0.014
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.014
muscle system process GO:0003012 141 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
multicellular organismal signaling GO:0035637 91 0.014
regulation of translation GO:0006417 71 0.014
rna interference GO:0016246 2 0.014
protein import into nucleus GO:0006606 95 0.014
cognition GO:0050890 149 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
dna templated transcription termination GO:0006353 4 0.013
neural precursor cell proliferation GO:0061351 121 0.013
dendrite development GO:0016358 115 0.013
developmental maturation GO:0021700 193 0.013
endocytosis GO:0006897 168 0.013
regulation of protein catabolic process GO:0042176 108 0.013
myeloid cell differentiation GO:0030099 233 0.013
meiotic chromosome condensation GO:0010032 3 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
transmembrane transport GO:0055085 412 0.013
response to organic cyclic compound GO:0014070 198 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
connective tissue development GO:0061448 179 0.013
response to organonitrogen compound GO:0010243 246 0.013
protein modification by small protein conjugation GO:0032446 187 0.013
guanosine containing compound metabolic process GO:1901068 144 0.013
cellular response to organic cyclic compound GO:0071407 87 0.013
glucose homeostasis GO:0042593 128 0.013
dna metabolic process GO:0006259 303 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of embryonic development GO:0045995 71 0.013
cartilage development GO:0051216 140 0.013
regulation of chromosome organization GO:0033044 83 0.013
response to radiation GO:0009314 165 0.012
regulation of organelle assembly GO:1902115 19 0.012
regulation of cell division GO:0051302 76 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
mitotic sister chromatid cohesion GO:0007064 1 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
protein polymerization GO:0051258 57 0.012
carbohydrate metabolic process GO:0005975 230 0.012
positive regulation of cell death GO:0010942 224 0.012
adult behavior GO:0030534 135 0.012
regulation of ossification GO:0030278 112 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
neural tube development GO:0021915 160 0.012
positive regulation of adaptive immune response GO:0002821 61 0.012
locomotory behavior GO:0007626 195 0.012
cytokine production GO:0001816 319 0.012
cellular lipid metabolic process GO:0044255 323 0.012
leukocyte mediated immunity GO:0002443 174 0.011
regulation of neuron projection development GO:0010975 169 0.011
positive regulation of immune effector process GO:0002699 107 0.011
skin development GO:0043588 220 0.011
transmission of nerve impulse GO:0019226 76 0.011
regulation of osteoblast differentiation GO:0045667 67 0.011
muscle contraction GO:0006936 101 0.011
spermatogenesis GO:0007283 284 0.011
pallium development GO:0021543 120 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
camera type eye development GO:0043010 266 0.011
regulation of b cell activation GO:0050864 81 0.011
regulation of cellular response to stress GO:0080135 159 0.011
protein acylation GO:0043543 64 0.011
heterochromatin assembly GO:0031507 2 0.011
response to growth factor GO:0070848 198 0.011
meiotic chromosome segregation GO:0045132 19 0.011
circulatory system process GO:0003013 197 0.011
positive regulation of nervous system development GO:0051962 221 0.011
cellular response to gamma radiation GO:0071480 4 0.011
microtubule polymerization or depolymerization GO:0031109 26 0.010
regulation of chromatin modification GO:1903308 57 0.010
regulation of chromatin silencing GO:0031935 2 0.010
regulation of neuron differentiation GO:0045664 281 0.010
positive regulation of cell cycle process GO:0090068 61 0.010
cellular response to external stimulus GO:0071496 88 0.010
cellular response to abiotic stimulus GO:0071214 56 0.010
activation of adenylate cyclase activity GO:0007190 4 0.010
peptidyl lysine modification GO:0018205 77 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
regulation of circadian rhythm GO:0042752 58 0.010
b cell activation GO:0042113 161 0.010
regulation of adaptive immune response GO:0002819 90 0.010
positive regulation of cell cycle GO:0045787 92 0.010
purine nucleoside monophosphate catabolic process GO:0009128 58 0.010
circadian regulation of gene expression GO:0032922 48 0.010

G2e3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.019
disease of anatomical entity DOID:7 0 0.019
eye and adnexa disease DOID:1492 0 0.019
nervous system disease DOID:863 0 0.019
eye disease DOID:5614 0 0.019
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010