Mus musculus

7 known processes

Casp6

caspase 6

(Aliases: Mch2,mCASP-6)

Casp6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of immune system process GO:0002683 209 0.092
Mouse
regulation of defense response GO:0031347 233 0.081
Mouse
cytokine production GO:0001816 319 0.078
Mouse
regulation of cytokine production GO:0001817 266 0.072
Mouse
protein maturation GO:0051604 176 0.068
Mouse Fly
protein processing GO:0016485 163 0.068
Mouse Fly
immune effector process GO:0002252 321 0.057
response to lipopolysaccharide GO:0032496 128 0.056
Mouse
oxidation reduction process GO:0055114 342 0.056
cellular amino acid metabolic process GO:0006520 103 0.053
negative regulation of protein metabolic process GO:0051248 282 0.051
Mouse
regulation of cell activation GO:0050865 289 0.050
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.050
Mouse
negative regulation of cell proliferation GO:0008285 296 0.048
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.047
amine metabolic process GO:0009308 45 0.046
response to molecule of bacterial origin GO:0002237 143 0.045
Mouse
regulation of hydrolase activity GO:0051336 246 0.044
Mouse Fly
innate immune response GO:0045087 157 0.042
leukocyte differentiation GO:0002521 342 0.041
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.041
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.041
Mouse
response to organic cyclic compound GO:0014070 198 0.041
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.040
Mouse
male gamete generation GO:0048232 285 0.040
Fly
cellular lipid metabolic process GO:0044255 323 0.039
apoptotic signaling pathway GO:0097190 306 0.039
Mouse Fly
dna metabolic process GO:0006259 303 0.038
Mouse
cellular ketone metabolic process GO:0042180 84 0.038
regulation of cellular amino acid metabolic process GO:0006521 5 0.037
negative regulation of molecular function GO:0044092 258 0.036
Mouse
regulation of transferase activity GO:0051338 263 0.036
Mouse
cellular response to lipid GO:0071396 145 0.036
Mouse
regulation of lymphocyte activation GO:0051249 240 0.036
Mouse
positive regulation of protein modification process GO:0031401 299 0.036
heterocycle catabolic process GO:0046700 280 0.036
Mouse
cellular amine metabolic process GO:0044106 44 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
negative regulation of protein modification process GO:0031400 163 0.034
Mouse
t cell activation GO:0042110 289 0.034
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.034
Mouse
negative regulation of protein phosphorylation GO:0001933 126 0.034
Mouse
homeostasis of number of cells GO:0048872 210 0.033
Mouse
regulation of membrane potential GO:0042391 192 0.033
Mouse
positive regulation of apoptotic process GO:0043065 217 0.033
Mouse Fly
inflammatory response GO:0006954 244 0.032
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.032
response to organonitrogen compound GO:0010243 246 0.032
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.032
Mouse
response to oxidative stress GO:0006979 123 0.031
Mouse
skeletal system development GO:0001501 356 0.031
regulation of cellular catabolic process GO:0031329 242 0.030
Mouse Fly
spermatogenesis GO:0007283 284 0.030
Fly
positive regulation of cell death GO:0010942 224 0.030
Mouse Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
t cell proliferation GO:0042098 120 0.030
Mouse
positive regulation of defense response GO:0031349 124 0.029
regulation of secretion by cell GO:1903530 249 0.029
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
positive regulation of cytokine production GO:0001819 174 0.029
Mouse
immune response regulating signaling pathway GO:0002764 125 0.029
mapk cascade GO:0000165 281 0.029
regulation of inflammatory response GO:0050727 147 0.028
Mouse
cytoplasmic transport GO:0016482 234 0.028
leukocyte mediated immunity GO:0002443 174 0.028
aromatic compound catabolic process GO:0019439 286 0.028
Mouse
macromolecule catabolic process GO:0009057 281 0.028
Mouse
negative regulation of kinase activity GO:0033673 81 0.028
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.028
defense response to other organism GO:0098542 197 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
regulation of innate immune response GO:0045088 91 0.027
lymphocyte mediated immunity GO:0002449 139 0.027
regulation of t cell activation GO:0050863 170 0.026
Mouse
activation of immune response GO:0002253 138 0.026
regulation of mapk cascade GO:0043408 248 0.026
ossification GO:0001503 216 0.026
cellular chemical homeostasis GO:0055082 215 0.026
positive regulation of programmed cell death GO:0043068 218 0.026
Mouse Fly
purine containing compound metabolic process GO:0072521 311 0.026
cation homeostasis GO:0055080 212 0.025
regulation of protein localization GO:0032880 231 0.025
Mouse
fatty acid metabolic process GO:0006631 121 0.025
purine nucleoside triphosphate catabolic process GO:0009146 203 0.025
leukocyte proliferation GO:0070661 172 0.025
Mouse
regulation of secretion GO:0051046 274 0.025
Mouse
transmembrane transport GO:0055085 412 0.025
purine nucleotide metabolic process GO:0006163 302 0.025
negative regulation of defense response GO:0031348 77 0.024
ras protein signal transduction GO:0007265 77 0.024
wound healing GO:0042060 157 0.024
monocarboxylic acid metabolic process GO:0032787 191 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
Mouse
regulation of protein kinase activity GO:0045859 232 0.024
Mouse
purine nucleotide catabolic process GO:0006195 211 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
leukocyte mediated cytotoxicity GO:0001909 62 0.023
regulation of peptidase activity GO:0052547 96 0.023
Mouse Fly
negative regulation of intracellular signal transduction GO:1902532 167 0.023
mitochondrion organization GO:0007005 134 0.023
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.023
positive regulation of protein transport GO:0051222 93 0.023
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.022
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
ion transmembrane transport GO:0034220 361 0.022
lipid biosynthetic process GO:0008610 179 0.022
sequestering of metal ion GO:0051238 19 0.022
lipid transport GO:0006869 98 0.022
cellular response to biotic stimulus GO:0071216 92 0.021
myeloid cell differentiation GO:0030099 233 0.021
Mouse
endomembrane system organization GO:0010256 147 0.021
cellular homeostasis GO:0019725 240 0.021
positive regulation of secretion GO:0051047 130 0.021
Mouse
regulation of cellular response to stress GO:0080135 159 0.021
Fly
regulation of protein maturation GO:1903317 96 0.021
nitrogen compound transport GO:0071705 271 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.021
positive regulation of hydrolase activity GO:0051345 148 0.020
Mouse Fly
sequestering of calcium ion GO:0051208 18 0.020
lymphocyte proliferation GO:0046651 164 0.020
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.020
regulation of leukocyte mediated immunity GO:0002703 104 0.020
nucleoside phosphate catabolic process GO:1901292 222 0.020
positive regulation of mapk cascade GO:0043410 170 0.019
ear development GO:0043583 200 0.019
positive regulation of apoptotic signaling pathway GO:2001235 95 0.019
Mouse Fly
cation transmembrane transport GO:0098655 266 0.019
regulation of map kinase activity GO:0043405 120 0.019
negative regulation of cell activation GO:0050866 111 0.019
Mouse
carboxylic acid catabolic process GO:0046395 51 0.019
regulation of adaptive immune response GO:0002819 90 0.019
divalent inorganic cation transport GO:0072511 178 0.019
blood circulation GO:0008015 195 0.019
muscle system process GO:0003012 141 0.019
negative regulation of phosphorylation GO:0042326 166 0.018
Mouse
bone development GO:0060348 120 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
regulation of response to wounding GO:1903034 189 0.018
Mouse
skeletal system morphogenesis GO:0048705 203 0.018
regulation of ossification GO:0030278 112 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
Mouse Fly
carbohydrate metabolic process GO:0005975 230 0.018
protein modification by small protein conjugation or removal GO:0070647 207 0.018
protein catabolic process GO:0030163 221 0.018
cellular response to extracellular stimulus GO:0031668 81 0.018
Fly
cytokine mediated signaling pathway GO:0019221 115 0.018
regulation of organelle organization GO:0033043 289 0.018
regulation of protein processing GO:0070613 96 0.018
nucleoside metabolic process GO:0009116 246 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
anion transport GO:0006820 177 0.018
positive regulation of transferase activity GO:0051347 167 0.018
peptidyl amino acid modification GO:0018193 336 0.018
lung development GO:0030324 164 0.017
organelle assembly GO:0070925 177 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
sensory perception GO:0007600 245 0.017
Mouse
organophosphate biosynthetic process GO:0090407 122 0.017
regulation of cell cycle GO:0051726 281 0.017
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.017
cytokine secretion GO:0050663 72 0.017
Mouse
embryonic organ morphogenesis GO:0048562 276 0.017
nucleotide catabolic process GO:0009166 217 0.017
myeloid leukocyte differentiation GO:0002573 119 0.017
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.017
muscle contraction GO:0006936 101 0.017
organic acid catabolic process GO:0016054 51 0.017
regulation of neuron differentiation GO:0045664 281 0.017
metal ion homeostasis GO:0055065 189 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
Mouse
response to hypoxia GO:0001666 58 0.017
Mouse
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of protein transport GO:0051223 163 0.017
Mouse
purine nucleoside catabolic process GO:0006152 205 0.017
sphingolipid biosynthetic process GO:0030148 26 0.017
nucleotide metabolic process GO:0009117 332 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
organic anion transport GO:0015711 137 0.017
sulfur compound metabolic process GO:0006790 100 0.016
spermatid differentiation GO:0048515 115 0.016
Fly
positive regulation of immune effector process GO:0002699 107 0.016
response to nutrient levels GO:0031667 109 0.016
Fly
respiratory tube development GO:0030323 167 0.016
divalent inorganic cation homeostasis GO:0072507 138 0.016
small molecule catabolic process GO:0044282 71 0.016
immune response activating signal transduction GO:0002757 116 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
ribonucleoside triphosphate metabolic process GO:0009199 220 0.016
positive regulation of map kinase activity GO:0043406 84 0.016
nucleoside catabolic process GO:0009164 206 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
synaptic transmission GO:0007268 329 0.016
Fly
ribose phosphate metabolic process GO:0019693 291 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
response to reactive oxygen species GO:0000302 56 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
Mouse
response to extracellular stimulus GO:0009991 127 0.016
Fly
positive regulation of cell development GO:0010720 237 0.016
Fly
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.015
purine containing compound catabolic process GO:0072523 213 0.015
intracellular protein transport GO:0006886 204 0.015
smoothened signaling pathway GO:0007224 105 0.015
protein secretion GO:0009306 111 0.015
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.015
Mouse
lateral inhibition GO:0046331 1 0.015
intrinsic apoptotic signaling pathway GO:0097193 132 0.015
Mouse
striated muscle contraction GO:0006941 45 0.015
negative regulation of protein processing GO:0010955 79 0.015
rhythmic process GO:0048511 174 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular ion homeostasis GO:0006873 165 0.015
dephosphorylation GO:0016311 129 0.015
negative regulation of leukocyte proliferation GO:0070664 46 0.015
Mouse
lymphocyte differentiation GO:0030098 242 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
leukocyte apoptotic process GO:0071887 71 0.015
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.015
adaptive immune response GO:0002250 155 0.015
regulation of t cell proliferation GO:0042129 92 0.015
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.015
guanosine containing compound catabolic process GO:1901069 144 0.015
organic hydroxy compound transport GO:0015850 93 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
regulation of interleukin 8 production GO:0032677 3 0.015
organelle localization GO:0051640 179 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
negative regulation of immune effector process GO:0002698 55 0.015
cation transport GO:0006812 399 0.015
regulation of cytokine secretion GO:0050707 61 0.015
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.015
organic acid transport GO:0015849 101 0.015
regulation of body fluid levels GO:0050878 162 0.015
response to growth factor GO:0070848 198 0.015
defense response to bacterium GO:0042742 119 0.015
hexose metabolic process GO:0019318 98 0.014
organophosphate catabolic process GO:0046434 232 0.014
membrane depolarization GO:0051899 64 0.014
Mouse
calcium ion homeostasis GO:0055074 127 0.014
regulation of protein catabolic process GO:0042176 108 0.014
lymphocyte homeostasis GO:0002260 64 0.014
Mouse
negative regulation of protein maturation GO:1903318 79 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
Mouse
regulation of kinase activity GO:0043549 249 0.014
Mouse
wnt signaling pathway GO:0016055 188 0.014
cell killing GO:0001906 67 0.014
positive regulation of interleukin 1 alpha production GO:0032730 4 0.014
Mouse
chemotaxis GO:0006935 247 0.014
respiratory system development GO:0060541 190 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.014
response to inorganic substance GO:0010035 96 0.014
regulation of protein secretion GO:0050708 82 0.014
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.014
cell activation involved in immune response GO:0002263 126 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
extracellular matrix organization GO:0030198 147 0.014
glycoprotein metabolic process GO:0009100 116 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
cellular lipid catabolic process GO:0044242 52 0.014
rho protein signal transduction GO:0007266 32 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
lipid localization GO:0010876 126 0.014
regulation of system process GO:0044057 200 0.014
regulation of hormone levels GO:0010817 211 0.014
divalent metal ion transport GO:0070838 172 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.013
urogenital system development GO:0001655 261 0.013
microtubule based process GO:0007017 236 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
Mouse
carbohydrate homeostasis GO:0033500 128 0.013
interleukin 1 production GO:0032612 31 0.013
Mouse
regulation of interleukin 1 beta production GO:0032651 25 0.013
Mouse
regulation of interferon gamma production GO:0032649 57 0.013
exocytosis GO:0006887 121 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
forebrain development GO:0030900 302 0.013
extracellular structure organization GO:0043062 148 0.013
methylation GO:0032259 134 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
positive regulation of innate immune response GO:0045089 80 0.013
negative regulation of cellular amine metabolic process GO:0033239 1 0.013
response to oxygen levels GO:0070482 62 0.013
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
Mouse
canonical wnt signaling pathway GO:0060070 130 0.013
asymmetric stem cell division GO:0098722 3 0.013
regulation of proteolysis GO:0030162 164 0.013
Mouse Fly
myeloid cell homeostasis GO:0002262 114 0.013
positive regulation of nervous system development GO:0051962 221 0.013
fertilization GO:0009566 127 0.013
cell adhesion GO:0007155 329 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
regulation of intracellular transport GO:0032386 159 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
Mouse Fly
i kappab kinase nf kappab signaling GO:0007249 85 0.013
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
regulation of interleukin 1 alpha production GO:0032650 4 0.013
Mouse
circulatory system process GO:0003013 197 0.013
small molecule biosynthetic process GO:0044283 132 0.013
epithelial cell proliferation GO:0050673 174 0.013
b cell proliferation GO:0042100 53 0.013
Mouse
regulation of cell projection organization GO:0031344 206 0.013
leukocyte homeostasis GO:0001776 79 0.012
Mouse
response to light stimulus GO:0009416 135 0.012
Mouse
compound eye development GO:0048749 1 0.012
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
germ cell development GO:0007281 185 0.012
Fly
positive regulation of kinase activity GO:0033674 155 0.012
response to acid chemical GO:0001101 111 0.012
gland development GO:0048732 330 0.012
Fly
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.012
rna processing GO:0006396 105 0.012
lipid catabolic process GO:0016042 69 0.012
cellular divalent inorganic cation homeostasis GO:0072503 127 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
cell type specific apoptotic process GO:0097285 268 0.012
Mouse Fly
angiogenesis GO:0001525 201 0.012
Mouse
spermatid development GO:0007286 108 0.012
positive regulation of leukocyte differentiation GO:1902107 86 0.012
activation of cysteine type endopeptidase activity GO:0097202 27 0.012
Mouse
cellular response to organic cyclic compound GO:0071407 87 0.012
Mouse
glucose homeostasis GO:0042593 128 0.012
cellular response to external stimulus GO:0071496 88 0.012
Fly
cellular metal ion homeostasis GO:0006875 151 0.012
regulation of neuron projection development GO:0010975 169 0.012
gtp metabolic process GO:0046039 144 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.012
Mouse
retrograde transport endosome to golgi GO:0042147 2 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
membrane organization GO:0061024 245 0.012
developmental maturation GO:0021700 193 0.012
Fly
cellular response to oxidative stress GO:0034599 76 0.012
Mouse
regulation of b cell activation GO:0050864 81 0.012
Mouse
axonogenesis GO:0007409 274 0.012
histone modification GO:0016570 159 0.012
cellular protein complex assembly GO:0043623 116 0.012
interleukin 6 production GO:0032635 58 0.012
t cell differentiation GO:0030217 174 0.012
transmission of nerve impulse GO:0019226 76 0.012
stem cell differentiation GO:0048863 268 0.012
antigen receptor mediated signaling pathway GO:0050851 64 0.012
negative regulation of cytokine production GO:0001818 84 0.012
regulation of cell killing GO:0031341 40 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.012
Mouse
anatomical structure homeostasis GO:0060249 145 0.012
response to starvation GO:0042594 65 0.012
Fly
developmental growth involved in morphogenesis GO:0060560 138 0.012
interleukin 1 beta production GO:0032611 30 0.012
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.012
cellular macromolecule catabolic process GO:0044265 206 0.012
Mouse
striated muscle tissue development GO:0014706 293 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
maintenance of location GO:0051235 89 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
Mouse Fly
negative regulation of mapk cascade GO:0043409 65 0.011
carboxylic acid transport GO:0046942 100 0.011
morphogenesis of a branching epithelium GO:0061138 193 0.011
peptide transport GO:0015833 133 0.011
interleukin 8 production GO:0032637 4 0.011
positive regulation of interleukin 1 beta production GO:0032731 16 0.011
Mouse
t cell mediated immunity GO:0002456 50 0.011
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.011
macromolecular complex disassembly GO:0032984 43 0.011
striated muscle cell development GO:0055002 125 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
regulation of cell migration GO:0030334 219 0.011
mrna metabolic process GO:0016071 84 0.011
cofactor metabolic process GO:0051186 80 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.011
Fly
peptide secretion GO:0002790 114 0.011
steroid metabolic process GO:0008202 119 0.011
b cell activation GO:0042113 161 0.011
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
erythrocyte differentiation GO:0030218 88 0.011
action potential GO:0001508 78 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
blood vessel morphogenesis GO:0048514 285 0.011
Mouse
mitotic cell cycle process GO:1903047 159 0.011
regulation of homeostatic process GO:0032844 182 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
hemostasis GO:0007599 78 0.011
cell substrate adhesion GO:0031589 130 0.011
regulation of cell motility GO:2000145 236 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.010
fat soluble vitamin biosynthetic process GO:0042362 4 0.010
interferon gamma production GO:0032609 67 0.010
peptidyl tyrosine phosphorylation GO:0018108 143 0.010
blood coagulation GO:0007596 76 0.010
organism emergence from protective structure GO:0071684 4 0.010
membrane lipid biosynthetic process GO:0046467 32 0.010
digestive system development GO:0055123 200 0.010
protein localization to organelle GO:0033365 185 0.010
negative regulation of cell development GO:0010721 169 0.010
regulation of striated muscle cell differentiation GO:0051153 81 0.010
cell growth GO:0016049 130 0.010
negative regulation of t cell activation GO:0050868 65 0.010
Mouse
pharynx development GO:0060465 1 0.010
positive regulation of t cell activation GO:0050870 101 0.010
placenta development GO:0001890 140 0.010
calcium ion transport GO:0006816 159 0.010
negative regulation of protein catabolic process GO:0042177 36 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.010
cofactor transport GO:0051181 4 0.010
renal system development GO:0072001 225 0.010
male sex differentiation GO:0046661 109 0.010
positive regulation of interleukin 8 production GO:0032757 2 0.010
t cell homeostasis GO:0043029 35 0.010
Mouse
b cell differentiation GO:0030183 78 0.010
tissue homeostasis GO:0001894 115 0.010
synaptic vesicle localization GO:0097479 59 0.010
protein complex disassembly GO:0043241 40 0.010
negative regulation of proteolysis GO:0045861 74 0.010
innate immune response activating signal transduction GO:0002758 50 0.010
establishment of organelle localization GO:0051656 122 0.010
multicellular organismal signaling GO:0035637 91 0.010

Casp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
immune system disease DOID:2914 0 0.011