Mus musculus

103 known processes

Casp9

caspase 9

(Aliases: AW493809,AI115399,ICE-LAP6,Mch6,Caspase-9)

Casp9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleobase containing small molecule metabolic process GO:0055086 352 0.234
cell type specific apoptotic process GO:0097285 268 0.191
cellular amine metabolic process GO:0044106 44 0.173
nucleoside phosphate metabolic process GO:0006753 338 0.153
purine ribonucleotide metabolic process GO:0009150 290 0.149
regulation of nucleotide metabolic process GO:0006140 169 0.147
ribonucleotide metabolic process GO:0009259 291 0.144
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.142
regulation of membrane potential GO:0042391 192 0.142
Mouse
nucleotide metabolic process GO:0009117 332 0.119
regulation of purine nucleotide metabolic process GO:1900542 169 0.118
response to organonitrogen compound GO:0010243 246 0.116
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.113
purine nucleotide metabolic process GO:0006163 302 0.112
purine containing compound metabolic process GO:0072521 311 0.106
positive regulation of protein modification process GO:0031401 299 0.099
regulation of secretion GO:0051046 274 0.099
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.096
positive regulation of nucleotide metabolic process GO:0045981 114 0.092
ribose phosphate metabolic process GO:0019693 291 0.091
regulation of cellular ketone metabolic process GO:0010565 66 0.090
ras protein signal transduction GO:0007265 77 0.087
gtp metabolic process GO:0046039 144 0.086
regulation of cellular amino acid metabolic process GO:0006521 5 0.085
cellular homeostasis GO:0019725 240 0.084
organic cyclic compound catabolic process GO:1901361 295 0.079
Mouse
nucleoside metabolic process GO:0009116 246 0.076
regulation of transferase activity GO:0051338 263 0.076
Mouse
organophosphate catabolic process GO:0046434 232 0.076
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.076
positive regulation of gtpase activity GO:0043547 85 0.075
carbohydrate derivative catabolic process GO:1901136 231 0.075
response to molecule of bacterial origin GO:0002237 143 0.073
Mouse
rhythmic process GO:0048511 174 0.072
glycosyl compound metabolic process GO:1901657 246 0.071
aromatic compound catabolic process GO:0019439 286 0.070
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.069
regulation of kinase activity GO:0043549 249 0.069
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.069
apoptotic signaling pathway GO:0097190 306 0.068
Human Mouse
positive regulation of kinase activity GO:0033674 155 0.067
response to peptide GO:1901652 136 0.066
positive regulation of protein phosphorylation GO:0001934 242 0.065
amine metabolic process GO:0009308 45 0.065
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.065
cation transport GO:0006812 399 0.063
heterocycle catabolic process GO:0046700 280 0.062
Mouse
purine nucleotide catabolic process GO:0006195 211 0.062
blood circulation GO:0008015 195 0.061
purine nucleoside metabolic process GO:0042278 241 0.061
spermatogenesis GO:0007283 284 0.061
nucleoside triphosphate catabolic process GO:0009143 205 0.061
guanosine containing compound metabolic process GO:1901068 144 0.060
rho protein signal transduction GO:0007266 32 0.057
nucleoside phosphate catabolic process GO:1901292 222 0.057
regulation of body fluid levels GO:0050878 162 0.057
germ cell development GO:0007281 185 0.057
cellular amino acid metabolic process GO:0006520 103 0.056
carbohydrate derivative biosynthetic process GO:1901137 183 0.056
peptidyl amino acid modification GO:0018193 336 0.055
mapk cascade GO:0000165 281 0.054
cellular response to lipid GO:0071396 145 0.053
regulation of cell migration GO:0030334 219 0.053
cation homeostasis GO:0055080 212 0.052
purine ribonucleoside catabolic process GO:0046130 205 0.052
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.052
response to light stimulus GO:0009416 135 0.052
nucleoside triphosphate metabolic process GO:0009141 230 0.050
wound healing GO:0042060 157 0.050
cellular response to peptide GO:1901653 92 0.048
regulation of secretion by cell GO:1903530 249 0.048
Mouse
positive regulation of apoptotic process GO:0043065 217 0.048
skeletal system development GO:0001501 356 0.047
response to peptide hormone GO:0043434 127 0.047
purine nucleoside triphosphate catabolic process GO:0009146 203 0.047
ribonucleoside metabolic process GO:0009119 245 0.046
organonitrogen compound catabolic process GO:1901565 264 0.046
regulation of cellular catabolic process GO:0031329 242 0.046
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.046
cellular nitrogen compound catabolic process GO:0044270 280 0.046
Mouse
negative regulation of cell development GO:0010721 169 0.045
cellular ketone metabolic process GO:0042180 84 0.045
response to extracellular stimulus GO:0009991 127 0.045
ribonucleoside catabolic process GO:0042454 206 0.045
regulation of protein kinase activity GO:0045859 232 0.044
Mouse
epithelial tube morphogenesis GO:0060562 303 0.044
Mouse
ribonucleotide catabolic process GO:0009261 208 0.044
guanosine containing compound catabolic process GO:1901069 144 0.044
calcium ion homeostasis GO:0055074 127 0.044
response to insulin GO:0032868 100 0.043
purine ribonucleotide catabolic process GO:0009154 208 0.043
purine containing compound catabolic process GO:0072523 213 0.043
positive regulation of ras gtpase activity GO:0032320 65 0.042
cellular response to organonitrogen compound GO:0071417 145 0.042
glycosyl compound catabolic process GO:1901658 206 0.042
positive regulation of gtp catabolic process GO:0033126 85 0.041
cellular lipid metabolic process GO:0044255 323 0.041
regulation of apoptotic signaling pathway GO:2001233 197 0.041
Mouse
regulation of neuron death GO:1901214 134 0.041
regulation of organelle organization GO:0033043 289 0.041
glycoprotein metabolic process GO:0009100 116 0.041
regulation of hormone levels GO:0010817 211 0.041
organic acid transport GO:0015849 101 0.040
cellular divalent inorganic cation homeostasis GO:0072503 127 0.040
circadian rhythm GO:0007623 114 0.040
mesodermal cell migration GO:0008078 4 0.039
innate immune response GO:0045087 157 0.039
nitrogen compound transport GO:0071705 271 0.039
forebrain development GO:0030900 302 0.039
regulation of cell cycle GO:0051726 281 0.039
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.039
Mouse
oocyte construction GO:0007308 2 0.039
multicellular organismal signaling GO:0035637 91 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.038
regulation of cell activation GO:0050865 289 0.038
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.037
reactive oxygen species metabolic process GO:0072593 84 0.037
oocyte axis specification GO:0007309 2 0.037
positive regulation of cell activation GO:0050867 158 0.036
peptide hormone secretion GO:0030072 109 0.036
response to organic cyclic compound GO:0014070 198 0.036
circulatory system process GO:0003013 197 0.036
negative regulation of cellular component organization GO:0051129 194 0.036
cellular response to hormone stimulus GO:0032870 150 0.036
regulation of cellular response to stress GO:0080135 159 0.036
Human
cellular metal ion homeostasis GO:0006875 151 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.035
placenta development GO:0001890 140 0.035
positive regulation of protein kinase activity GO:0045860 144 0.035
regulation of peptide transport GO:0090087 91 0.035
cytoplasmic transport GO:0016482 234 0.035
ameboidal type cell migration GO:0001667 128 0.035
microtubule based process GO:0007017 236 0.035
regulation of cellular component biogenesis GO:0044087 181 0.035
carbohydrate metabolic process GO:0005975 230 0.034
regulation of inflammatory response GO:0050727 147 0.034
Mouse
purine nucleoside catabolic process GO:0006152 205 0.034
regulation of homeostatic process GO:0032844 182 0.034
response to lipopolysaccharide GO:0032496 128 0.034
Mouse
protein maturation GO:0051604 176 0.034
muscle cell differentiation GO:0042692 261 0.034
regulation of response to wounding GO:1903034 189 0.034
Mouse
metal ion homeostasis GO:0055065 189 0.033
actin cytoskeleton organization GO:0030036 220 0.033
regulation of nucleoside metabolic process GO:0009118 130 0.033
divalent inorganic cation homeostasis GO:0072507 138 0.033
neuronal action potential GO:0019228 54 0.033
stem cell differentiation GO:0048863 268 0.033
neural precursor cell proliferation GO:0061351 121 0.033
membrane organization GO:0061024 245 0.033
regulation of cell motility GO:2000145 236 0.032
anion transport GO:0006820 177 0.032
tissue remodeling GO:0048771 102 0.032
regulation of gtp catabolic process GO:0033124 113 0.032
negative regulation of protein metabolic process GO:0051248 282 0.032
Mouse
cation transmembrane transport GO:0098655 266 0.032
transmembrane transport GO:0055085 412 0.031
myeloid leukocyte differentiation GO:0002573 119 0.031
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
extrinsic apoptotic signaling pathway GO:0097191 126 0.031
Mouse
protein catabolic process GO:0030163 221 0.031
protein ubiquitination GO:0016567 171 0.031
amide transport GO:0042886 138 0.031
protein modification by small protein conjugation or removal GO:0070647 207 0.031
cellular ion homeostasis GO:0006873 165 0.031
positive regulation of programmed cell death GO:0043068 218 0.031
cellular chemical homeostasis GO:0055082 215 0.030
protein modification by small protein conjugation GO:0032446 187 0.030
negative regulation of phosphate metabolic process GO:0045936 184 0.030
Mouse
immune effector process GO:0002252 321 0.030
macromolecule catabolic process GO:0009057 281 0.030
Mouse
positive regulation of transferase activity GO:0051347 167 0.030
apoptotic mitochondrial changes GO:0008637 48 0.030
Mouse
organelle localization GO:0051640 179 0.030
endomembrane system organization GO:0010256 147 0.030
regulation of neuron apoptotic process GO:0043523 122 0.030
regulation of reactive oxygen species metabolic process GO:2000377 40 0.030
response to radiation GO:0009314 165 0.029
nucleotide catabolic process GO:0009166 217 0.029
t cell activation GO:0042110 289 0.029
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
regulation of protein serine threonine kinase activity GO:0071900 157 0.029
Mouse
regulation of multi organism process GO:0043900 111 0.029
inorganic cation transmembrane transport GO:0098662 207 0.029
leukocyte differentiation GO:0002521 342 0.029
Mouse
endocytosis GO:0006897 168 0.029
carboxylic acid transport GO:0046942 100 0.029
organonitrogen compound biosynthetic process GO:1901566 192 0.028
male gamete generation GO:0048232 285 0.028
nucleoside phosphate biosynthetic process GO:1901293 79 0.028
developmental maturation GO:0021700 193 0.028
engulfment of apoptotic cell GO:0043652 3 0.028
maintenance of location GO:0051235 89 0.027
regulation of ion homeostasis GO:2000021 64 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.027
sequestering of calcium ion GO:0051208 18 0.027
organic anion transport GO:0015711 137 0.027
urogenital system development GO:0001655 261 0.027
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.027
protein localization to organelle GO:0033365 185 0.027
divalent inorganic cation transport GO:0072511 178 0.027
regulation of protein localization GO:0032880 231 0.027
Mouse
regionalization GO:0003002 337 0.027
negative regulation of molecular function GO:0044092 258 0.027
Mouse
multicellular organismal homeostasis GO:0048871 164 0.027
peptide secretion GO:0002790 114 0.026
positive regulation of homeostatic process GO:0032846 64 0.026
cytosolic calcium ion homeostasis GO:0051480 70 0.026
nucleoside catabolic process GO:0009164 206 0.026
hormone secretion GO:0046879 128 0.026
negative regulation of cellular protein metabolic process GO:0032269 247 0.026
Mouse
camera type eye development GO:0043010 266 0.026
protein targeting GO:0006605 143 0.026
positive regulation of organelle organization GO:0010638 128 0.026
dna metabolic process GO:0006259 303 0.026
Mouse
intracellular protein transport GO:0006886 204 0.026
sequestering of metal ion GO:0051238 19 0.026
glycosylation GO:0070085 62 0.026
organophosphate biosynthetic process GO:0090407 122 0.025
divalent metal ion transport GO:0070838 172 0.025
regulation of hydrolase activity GO:0051336 246 0.025
positive regulation of nucleoside metabolic process GO:0045979 91 0.025
regulation of intracellular transport GO:0032386 159 0.025
action potential GO:0001508 78 0.025
oxidation reduction process GO:0055114 342 0.025
positive regulation of secretion by cell GO:1903532 114 0.024
Mouse
cellular response to biotic stimulus GO:0071216 92 0.024
compound eye development GO:0048749 1 0.024
embryonic appendage morphogenesis GO:0035113 126 0.024
positive regulation of cell death GO:0010942 224 0.024
carbohydrate homeostasis GO:0033500 128 0.024
regulation of reproductive process GO:2000241 66 0.024
morphogenesis of a branching structure GO:0001763 203 0.024
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.024
glycoprotein biosynthetic process GO:0009101 89 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.023
response to inorganic substance GO:0010035 96 0.023
peptide transport GO:0015833 133 0.023
fatty acid metabolic process GO:0006631 121 0.023
oocyte anterior posterior axis specification GO:0007314 2 0.023
regulation of neuron differentiation GO:0045664 281 0.023
negative regulation of protein phosphorylation GO:0001933 126 0.023
Mouse
insulin secretion GO:0030073 89 0.022
purine nucleotide biosynthetic process GO:0006164 65 0.022
actin filament bundle assembly GO:0051017 40 0.022
neuron apoptotic process GO:0051402 142 0.022
embryonic epithelial tube formation GO:0001838 130 0.022
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.022
lipid localization GO:0010876 126 0.022
transmission of nerve impulse GO:0019226 76 0.022
cytokine production GO:0001816 319 0.022
Mouse
protein localization to nucleus GO:0034504 121 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.022
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.022
Mouse
regulation of ion transport GO:0043269 215 0.022
epithelial tube formation GO:0072175 130 0.022
Mouse
development of primary sexual characteristics GO:0045137 143 0.022
ribose phosphate biosynthetic process GO:0046390 59 0.022
intracellular mrna localization GO:0008298 4 0.022
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.022
amino acid transport GO:0006865 61 0.021
regulation of rho gtpase activity GO:0032319 58 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
response to drug GO:0042493 75 0.021
response to nutrient levels GO:0031667 109 0.021
response to oxidative stress GO:0006979 123 0.020
Mouse
cell maturation GO:0048469 127 0.020
t cell differentiation GO:0030217 174 0.020
anatomical structure homeostasis GO:0060249 145 0.020
myotube differentiation GO:0014902 105 0.020
leukocyte migration GO:0050900 124 0.020
sulfur compound metabolic process GO:0006790 100 0.020
protein secretion GO:0009306 111 0.020
Mouse
regulation of peptide hormone secretion GO:0090276 75 0.020
regulation of hormone secretion GO:0046883 88 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
positive regulation of lymphocyte activation GO:0051251 140 0.020
regulation of heart contraction GO:0008016 77 0.020
neurotransmitter secretion GO:0007269 62 0.020
proteasomal protein catabolic process GO:0010498 98 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
macromolecule glycosylation GO:0043413 55 0.019
negative regulation of synapse assembly GO:0051964 3 0.019
oogenesis GO:0048477 56 0.019
female gamete generation GO:0007292 74 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
regulation of purine nucleotide catabolic process GO:0033121 122 0.019
regulation of interleukin 8 production GO:0032677 3 0.019
regulation of mapk cascade GO:0043408 248 0.019
protein processing GO:0016485 163 0.019
regulation of cell projection organization GO:0031344 206 0.019
morphogenesis of embryonic epithelium GO:0016331 159 0.018
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of defense response GO:0031347 233 0.018
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.018
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.018
negative regulation of phosphorylation GO:0042326 166 0.018
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
regulation of feeding behavior GO:0060259 3 0.018
myeloid cell differentiation GO:0030099 233 0.018
Mouse
ion transmembrane transport GO:0034220 361 0.018
tube formation GO:0035148 140 0.018
Mouse
alpha beta t cell activation GO:0046631 91 0.018
cd4 positive alpha beta t cell activation GO:0035710 45 0.018
regulation of proteolysis GO:0030162 164 0.017
neuron neuron synaptic transmission GO:0007270 69 0.017
neuron death GO:0070997 154 0.017
leukocyte activation involved in immune response GO:0002366 126 0.017
female sex differentiation GO:0046660 84 0.017
regulation of metal ion transport GO:0010959 106 0.017
positive regulation of ion transport GO:0043270 65 0.017
sensory organ morphogenesis GO:0090596 242 0.017
actin filament organization GO:0007015 113 0.017
neural tube development GO:0021915 160 0.017
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.017
exocytosis GO:0006887 121 0.017
regulation of map kinase activity GO:0043405 120 0.017
connective tissue development GO:0061448 179 0.017
regulation of neurotransmitter levels GO:0001505 87 0.017
generation of precursor metabolites and energy GO:0006091 103 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
synaptic vesicle localization GO:0097479 59 0.017
canonical wnt signaling pathway GO:0060070 130 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.017
synaptic vesicle transport GO:0048489 57 0.016
myelination GO:0042552 74 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
Mouse
stress activated protein kinase signaling cascade GO:0031098 81 0.016
nucleotide biosynthetic process GO:0009165 78 0.016
angiogenesis GO:0001525 201 0.016
Mouse
cellular response to acid chemical GO:0071229 68 0.016
muscle system process GO:0003012 141 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
regulation of cytoskeleton organization GO:0051493 122 0.016
activation of mapk activity GO:0000187 59 0.016
response to steroid hormone GO:0048545 56 0.016
regulation of cytokine production GO:0001817 266 0.016
Mouse
cell activation involved in immune response GO:0002263 126 0.016
positive regulation of camp metabolic process GO:0030816 19 0.016
translation GO:0006412 93 0.016
regulation of binding GO:0051098 111 0.016
regulation of anatomical structure size GO:0090066 178 0.016
gland development GO:0048732 330 0.016
gtp catabolic process GO:0006184 143 0.016
regulation of blood circulation GO:1903522 93 0.016
learning or memory GO:0007611 148 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
meiotic nuclear division GO:0007126 115 0.016
positive regulation of proteolysis GO:0045862 85 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
Human Mouse
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.016
negative regulation of protein modification process GO:0031400 163 0.016
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.016
purine ribonucleotide biosynthetic process GO:0009152 59 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
cellular response to abiotic stimulus GO:0071214 56 0.015
Human
cellular response to growth factor stimulus GO:0071363 197 0.015
cellular component assembly involved in morphogenesis GO:0010927 139 0.015
calcium ion transport GO:0006816 159 0.015
response to acid chemical GO:0001101 111 0.015
female gonad development GO:0008585 71 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.015
hemostasis GO:0007599 78 0.015
ribonucleotide biosynthetic process GO:0009260 59 0.015
pallium development GO:0021543 120 0.015
axon ensheathment GO:0008366 76 0.015
stem cell development GO:0048864 219 0.015
multi multicellular organism process GO:0044706 109 0.015
cellular response to steroid hormone stimulus GO:0071383 33 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
digestive tract development GO:0048565 190 0.015
renal system development GO:0072001 225 0.015
regulation of vasculature development GO:1901342 88 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.015
regulation of actin filament based process GO:0032970 99 0.015
purine containing compound biosynthetic process GO:0072522 70 0.015
regulation of t cell activation GO:0050863 170 0.015
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.015
positive regulation of cell migration GO:0030335 109 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
cognition GO:0050890 149 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
regulation of protein transport GO:0051223 163 0.015
Mouse
monosaccharide metabolic process GO:0005996 106 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
neural tube formation GO:0001841 108 0.015
Mouse
multi organism behavior GO:0051705 62 0.015
regulation of cysteine type endopeptidase activity GO:2000116 65 0.015
gastrulation GO:0007369 116 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
establishment of vesicle localization GO:0051650 81 0.015
actin filament polymerization GO:0030041 44 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
protein localization to membrane GO:0072657 108 0.014
coenzyme metabolic process GO:0006732 52 0.014
cellular protein catabolic process GO:0044257 155 0.014
regulation of cell size GO:0008361 72 0.014
l alpha amino acid transmembrane transport GO:1902475 23 0.014
somitogenesis GO:0001756 69 0.014
peptidyl serine modification GO:0018209 83 0.014
camp metabolic process GO:0046058 40 0.014
cellular response to external stimulus GO:0071496 88 0.014
hexose metabolic process GO:0019318 98 0.014
vesicle organization GO:0016050 60 0.014
positive regulation of cell development GO:0010720 237 0.014
dendrite development GO:0016358 115 0.014
neural tube closure GO:0001843 90 0.014
heart process GO:0003015 94 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
muscle tissue development GO:0060537 308 0.014
neurotransmitter transport GO:0006836 76 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
digestive system development GO:0055123 200 0.014
activation of adenylate cyclase activity GO:0007190 4 0.014
pole plasm assembly GO:0007315 2 0.014
primary neural tube formation GO:0014020 95 0.014
sulfur compound biosynthetic process GO:0044272 37 0.014
plasma membrane organization GO:0007009 90 0.014
regulation of ras protein signal transduction GO:0046578 114 0.014
lipid biosynthetic process GO:0008610 179 0.014
regulation of rho protein signal transduction GO:0035023 71 0.014
positive regulation of secretion GO:0051047 130 0.014
Mouse
establishment of protein localization to membrane GO:0090150 54 0.014
negative regulation of neuron apoptotic process GO:0043524 92 0.013
regulation of lipid metabolic process GO:0019216 118 0.013
negative regulation of inflammatory response GO:0050728 61 0.013
osteoclast differentiation GO:0030316 62 0.013
negative regulation of cell proliferation GO:0008285 296 0.013
Mouse
blood coagulation GO:0007596 76 0.013
chemotaxis GO:0006935 247 0.013
single organism cell adhesion GO:0098602 156 0.013
glucose import GO:0046323 32 0.013
modification dependent protein catabolic process GO:0019941 133 0.013
regulation of system process GO:0044057 200 0.013
regulation of actin cytoskeleton organization GO:0032956 84 0.013
negative regulation of growth GO:0045926 99 0.013
actin filament based movement GO:0030048 23 0.013
monosaccharide transport GO:0015749 58 0.013
organelle assembly GO:0070925 177 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
circadian regulation of gene expression GO:0032922 48 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
negative regulation of organelle organization GO:0010639 90 0.013
acetylcholine transport GO:0015870 2 0.013
spermatid development GO:0007286 108 0.013
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.013
fat cell differentiation GO:0045444 160 0.013
interleukin 8 production GO:0032637 4 0.013
synaptic transmission GO:0007268 329 0.013
oocyte differentiation GO:0009994 35 0.013
protein autophosphorylation GO:0046777 61 0.013
detection of stimulus GO:0051606 84 0.013
glucose homeostasis GO:0042593 128 0.012
negative regulation of phosphorus metabolic process GO:0010563 184 0.012
Mouse
bone remodeling GO:0046849 53 0.012
regulation of cell adhesion GO:0030155 154 0.012
phospholipid metabolic process GO:0006644 87 0.012
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.012
regulation of interleukin 10 secretion GO:2001179 4 0.012
mitochondrion organization GO:0007005 134 0.012
Mouse
appendage development GO:0048736 166 0.012
nuclear import GO:0051170 95 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.012
cellular response to extracellular stimulus GO:0031668 81 0.012
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.012
jnk cascade GO:0007254 72 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
tissue migration GO:0090130 68 0.012
meiotic cell cycle GO:0051321 122 0.012
bone development GO:0060348 120 0.012
dephosphorylation GO:0016311 129 0.012
limb development GO:0060173 166 0.012
lymphocyte differentiation GO:0030098 242 0.012

Casp9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.038
central nervous system disease DOID:331 0 0.026
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
sensory system disease DOID:0050155 0 0.013