Mus musculus

0 known processes

Sephs1

selenophosphate synthetase 1

(Aliases: AW111620,SELD,SPS,SPS1,AA589574,AI505014,1110046B24Rik)

Sephs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.081
lateral inhibition GO:0046331 1 0.076
organelle fission GO:0048285 170 0.072
germ cell development GO:0007281 185 0.062
oocyte axis specification GO:0007309 2 0.058
nuclear division GO:0000280 158 0.056
chromatin modification GO:0016568 187 0.056
cellular ketone metabolic process GO:0042180 84 0.056
regulation of cell activation GO:0050865 289 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.055
male gamete generation GO:0048232 285 0.047
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
mitotic cell cycle process GO:1903047 159 0.044
leukocyte differentiation GO:0002521 342 0.042
oocyte anterior posterior axis specification GO:0007314 2 0.042
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.042
regulation of cellular amine metabolic process GO:0033238 20 0.040
spermatogenesis GO:0007283 284 0.039
intrinsic apoptotic signaling pathway GO:0097193 132 0.039
regulation of t cell activation GO:0050863 170 0.037
meiotic nuclear division GO:0007126 115 0.037
apoptotic signaling pathway GO:0097190 306 0.037
covalent chromatin modification GO:0016569 163 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
cellular response to growth factor stimulus GO:0071363 197 0.035
aromatic compound catabolic process GO:0019439 286 0.035
pole plasm assembly GO:0007315 2 0.034
innate immune response GO:0045087 157 0.034
negative regulation of immune system process GO:0002683 209 0.034
regulation of secretion GO:0051046 274 0.033
nucleotide catabolic process GO:0009166 217 0.033
regulation of cell cycle GO:0051726 281 0.033
nucleotide metabolic process GO:0009117 332 0.033
protein modification by small protein conjugation GO:0032446 187 0.033
developmental maturation GO:0021700 193 0.033
cell fate commitment GO:0045165 210 0.032
maternal determination of anterior posterior axis embryo GO:0008358 2 0.032
lymphocyte differentiation GO:0030098 242 0.032
cytoplasmic transport GO:0016482 234 0.031
regulation of lymphocyte activation GO:0051249 240 0.031
epithelial tube morphogenesis GO:0060562 303 0.031
b cell activation GO:0042113 161 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.030
oocyte construction GO:0007308 2 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.030
regulation of establishment of protein localization GO:0070201 181 0.030
cellular amine metabolic process GO:0044106 44 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
amine metabolic process GO:0009308 45 0.029
response to uv GO:0009411 44 0.029
compound eye development GO:0048749 1 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
cellular amino acid metabolic process GO:0006520 103 0.028
multicellular organism growth GO:0035264 161 0.028
histone modification GO:0016570 159 0.028
regulation of defense response GO:0031347 233 0.028
inflammatory response GO:0006954 244 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
regulation of organelle organization GO:0033043 289 0.027
regulation of response to wounding GO:1903034 189 0.027
peptidyl amino acid modification GO:0018193 336 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
cytokine production GO:0001816 319 0.027
protein localization to organelle GO:0033365 185 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.026
cellular lipid metabolic process GO:0044255 323 0.026
chromatin organization GO:0006325 206 0.026
regulation of protein kinase activity GO:0045859 232 0.026
regulation of secretion by cell GO:1903530 249 0.026
response to radiation GO:0009314 165 0.026
t cell activation GO:0042110 289 0.026
macromolecule catabolic process GO:0009057 281 0.025
regulation of membrane potential GO:0042391 192 0.025
cilium morphogenesis GO:0060271 102 0.025
dna metabolic process GO:0006259 303 0.024
ribonucleoside metabolic process GO:0009119 245 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
positive regulation of protein modification process GO:0031401 299 0.024
hematopoietic progenitor cell differentiation GO:0002244 143 0.024
response to growth factor GO:0070848 198 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
cation transmembrane transport GO:0098655 266 0.024
heterocycle catabolic process GO:0046700 280 0.023
transmembrane transport GO:0055085 412 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
ribonucleotide catabolic process GO:0009261 208 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
purine containing compound catabolic process GO:0072523 213 0.023
protein modification by small protein conjugation or removal GO:0070647 207 0.023
purine containing compound metabolic process GO:0072521 311 0.023
negative regulation of mitotic cell cycle GO:0045930 58 0.023
organelle assembly GO:0070925 177 0.023
lymphocyte mediated immunity GO:0002449 139 0.022
meiotic cell cycle GO:0051321 122 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
cell maturation GO:0048469 127 0.022
spermatid differentiation GO:0048515 115 0.022
nucleobase containing small molecule metabolic process GO:0055086 352 0.021
nuclear import GO:0051170 95 0.021
positive regulation of cell activation GO:0050867 158 0.021
regulation of cellular component biogenesis GO:0044087 181 0.021
positive regulation of secretion GO:0051047 130 0.021
skeletal system development GO:0001501 356 0.021
nucleoside catabolic process GO:0009164 206 0.021
lipid biosynthetic process GO:0008610 179 0.021
development of primary sexual characteristics GO:0045137 143 0.021
ribonucleoside catabolic process GO:0042454 206 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
negative regulation of phosphorus metabolic process GO:0010563 184 0.020
negative regulation of cell activation GO:0050866 111 0.020
mitotic cell cycle GO:0000278 195 0.020
regulation of cell cycle process GO:0010564 160 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
meiosis i GO:0007127 60 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.019
regulation of transferase activity GO:0051338 263 0.019
morphogenesis of a branching structure GO:0001763 203 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
kidney development GO:0001822 213 0.019
response to light stimulus GO:0009416 135 0.019
intracellular mrna localization GO:0008298 4 0.019
response to lipopolysaccharide GO:0032496 128 0.019
regulation of kinase activity GO:0043549 249 0.019
regulation of t cell proliferation GO:0042129 92 0.019
multicellular organismal signaling GO:0035637 91 0.019
mrna processing GO:0006397 63 0.019
nucleoside metabolic process GO:0009116 246 0.018
regulation of cellular response to stress GO:0080135 159 0.018
spermatid development GO:0007286 108 0.018
dna recombination GO:0006310 92 0.018
double strand break repair GO:0006302 48 0.018
blood circulation GO:0008015 195 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
epidermis development GO:0008544 187 0.018
organonitrogen compound catabolic process GO:1901565 264 0.018
leukocyte proliferation GO:0070661 172 0.018
immune effector process GO:0002252 321 0.018
t cell proliferation GO:0042098 120 0.018
regulation of lymphocyte proliferation GO:0050670 117 0.018
regulation of interleukin 1 alpha production GO:0032650 4 0.018
regulation of chromosome organization GO:0033044 83 0.017
peptidyl lysine modification GO:0018205 77 0.017
regulation of inflammatory response GO:0050727 147 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
rna splicing via transesterification reactions GO:0000375 43 0.017
mrna splicing via spliceosome GO:0000398 43 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
urogenital system development GO:0001655 261 0.017
cellular homeostasis GO:0019725 240 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
regulation of multi organism process GO:0043900 111 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
oxidation reduction process GO:0055114 342 0.017
nitrogen compound transport GO:0071705 271 0.017
negative regulation of cell cycle GO:0045786 123 0.017
protein maturation GO:0051604 176 0.017
positive regulation of growth GO:0045927 104 0.017
regulation of protein transport GO:0051223 163 0.016
regulation of innate immune response GO:0045088 91 0.016
regulation of cell cycle g2 m phase transition GO:1902749 10 0.016
adaptive immune response GO:0002250 155 0.016
cellular response to cytokine stimulus GO:0071345 189 0.016
divalent metal ion transport GO:0070838 172 0.016
rna processing GO:0006396 105 0.016
asymmetric stem cell division GO:0098722 3 0.016
purine ribonucleoside metabolic process GO:0046128 241 0.016
regionalization GO:0003002 337 0.016
locomotory behavior GO:0007626 195 0.016
somatic cell dna recombination GO:0016444 51 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
myeloid cell differentiation GO:0030099 233 0.016
protein targeting GO:0006605 143 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
ossification GO:0001503 216 0.016
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
production of molecular mediator of immune response GO:0002440 103 0.015
intracellular protein transport GO:0006886 204 0.015
histone lysine methylation GO:0034968 50 0.015
leukocyte mediated immunity GO:0002443 174 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
modification dependent macromolecule catabolic process GO:0043632 133 0.015
membrane depolarization GO:0051899 64 0.015
response to molecule of bacterial origin GO:0002237 143 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.015
olfactory learning GO:0008355 2 0.015
cell activation involved in immune response GO:0002263 126 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
negative regulation of molecular function GO:0044092 258 0.015
cation transport GO:0006812 399 0.015
gland development GO:0048732 330 0.015
inorganic cation transmembrane transport GO:0098662 207 0.015
fat cell differentiation GO:0045444 160 0.015
positive regulation of innate immune response GO:0045089 80 0.015
response to acid chemical GO:0001101 111 0.015
regulation of protein localization GO:0032880 231 0.015
cellular response to lipid GO:0071396 145 0.015
regulation of cytokine production GO:0001817 266 0.015
positive regulation of cellular component biogenesis GO:0044089 94 0.015
negative regulation of defense response GO:0031348 77 0.014
negative regulation of t cell activation GO:0050868 65 0.014
nuclear transport GO:0051169 139 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
blastocyst development GO:0001824 80 0.014
synapse organization GO:0050808 125 0.014
organophosphate catabolic process GO:0046434 232 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
membrane organization GO:0061024 245 0.014
single organism nuclear import GO:1902593 95 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
dna repair GO:0006281 107 0.014
protein ubiquitination GO:0016567 171 0.014
myeloid leukocyte differentiation GO:0002573 119 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
regulation of hormone levels GO:0010817 211 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
protein localization to nucleus GO:0034504 121 0.014
morphogenesis of embryonic epithelium GO:0016331 159 0.014
response to organic cyclic compound GO:0014070 198 0.014
ion transmembrane transport GO:0034220 361 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
negative regulation of response to wounding GO:1903035 77 0.014
tube formation GO:0035148 140 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
carbohydrate homeostasis GO:0033500 128 0.014
circulatory system process GO:0003013 197 0.014
cellular response to hormone stimulus GO:0032870 150 0.013
carbohydrate metabolic process GO:0005975 230 0.013
protein catabolic process GO:0030163 221 0.013
connective tissue development GO:0061448 179 0.013
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.013
chromosome segregation GO:0007059 48 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
epithelial tube formation GO:0072175 130 0.013
oogenesis GO:0048477 56 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
cation homeostasis GO:0055080 212 0.013
organic anion transport GO:0015711 137 0.013
cellular response to abiotic stimulus GO:0071214 56 0.013
sensory perception GO:0007600 245 0.013
protein import into nucleus GO:0006606 95 0.013
regulation of intracellular transport GO:0032386 159 0.013
response to organonitrogen compound GO:0010243 246 0.013
neuronal action potential GO:0019228 54 0.013
lymphocyte proliferation GO:0046651 164 0.013
digestive tract morphogenesis GO:0048546 147 0.012
translation GO:0006412 93 0.012
negative regulation of lymphocyte activation GO:0051250 91 0.012
lipid localization GO:0010876 126 0.012
transmission of nerve impulse GO:0019226 76 0.012
cellular protein catabolic process GO:0044257 155 0.012
establishment of protein localization to organelle GO:0072594 118 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
ribonucleoside monophosphate catabolic process GO:0009158 57 0.012
cellular response to peptide GO:1901653 92 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
respiratory system development GO:0060541 190 0.012
digestive system development GO:0055123 200 0.012
chemotaxis GO:0006935 247 0.012
action potential GO:0001508 78 0.012
protein secretion GO:0009306 111 0.012
divalent inorganic cation transport GO:0072511 178 0.012
protein acylation GO:0043543 64 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
atp catabolic process GO:0006200 55 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
histone methylation GO:0016571 71 0.012
establishment or maintenance of neuroblast polarity GO:0045196 1 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
meiotic cell cycle process GO:1903046 77 0.012
interleukin 1 alpha secretion GO:0050703 3 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
cell type specific apoptotic process GO:0097285 268 0.012
regulation of homeostatic process GO:0032844 182 0.012
skin development GO:0043588 220 0.012
blood vessel morphogenesis GO:0048514 285 0.012
b cell differentiation GO:0030183 78 0.012
negative regulation of protein modification process GO:0031400 163 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of neuron differentiation GO:0045664 281 0.011
protein import GO:0017038 101 0.011
response to extracellular stimulus GO:0009991 127 0.011
regulation of lipid metabolic process GO:0019216 118 0.011
adult behavior GO:0030534 135 0.011
germ line stem cell division GO:0042078 2 0.011
protein methylation GO:0006479 81 0.011
immunoglobulin production GO:0002377 73 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
homeostasis of number of cells GO:0048872 210 0.011
asymmetric neuroblast division GO:0055059 1 0.011
polarity specification of proximal distal axis GO:0010085 2 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
t cell differentiation GO:0030217 174 0.011
stem cell differentiation GO:0048863 268 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.011
sequestering of calcium ion GO:0051208 18 0.011
positive regulation of transferase activity GO:0051347 167 0.011
negative regulation of leukocyte proliferation GO:0070664 46 0.011
sensory perception of sound GO:0007605 97 0.011
negative regulation of cell cycle phase transition GO:1901988 48 0.011
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.010
response to peptide GO:1901652 136 0.010
organonitrogen compound biosynthetic process GO:1901566 192 0.010
hormone secretion GO:0046879 128 0.010
circadian rhythm GO:0007623 114 0.010
ear development GO:0043583 200 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
regulation of mapk cascade GO:0043408 248 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
respiratory tube development GO:0030323 167 0.010
gonad development GO:0008406 141 0.010
amide transport GO:0042886 138 0.010
positive regulation of nervous system development GO:0051962 221 0.010
bone development GO:0060348 120 0.010
endocytosis GO:0006897 168 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
neural tube development GO:0021915 160 0.010

Sephs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
immune system disease DOID:2914 0 0.010