Mus musculus

24 known processes

Robo4

roundabout homolog 4 (Drosophila)

(Aliases: 1200012D01Rik,AI593217)

Robo4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organismal cell cell adhesion GO:0016337 131 0.428
Fly
oxidation reduction process GO:0055114 342 0.243
cellular amine metabolic process GO:0044106 44 0.204
cell adhesion GO:0007155 329 0.203
Zebrafish Fly
nucleoside phosphate metabolic process GO:0006753 338 0.188
fat cell differentiation GO:0045444 160 0.168
av node cell to bundle of his cell communication GO:0086067 2 0.162
regulation of gtp catabolic process GO:0033124 113 0.160
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.154
regulation of transferase activity GO:0051338 263 0.149
purine ribonucleoside metabolic process GO:0046128 241 0.148
urogenital system development GO:0001655 261 0.146
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.132
cellular ketone metabolic process GO:0042180 84 0.128
negative regulation of cell proliferation GO:0008285 296 0.126
Mouse
kidney development GO:0001822 213 0.123
Mouse
organ growth GO:0035265 117 0.122
regulation of hydrolase activity GO:0051336 246 0.114
regulation of leukocyte differentiation GO:1902105 159 0.114
tissue migration GO:0090130 68 0.113
Zebrafish Fly
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.113
negative regulation of endothelial cell migration GO:0010596 4 0.099
small gtpase mediated signal transduction GO:0007264 97 0.099
Zebrafish
nucleoside metabolic process GO:0009116 246 0.099
cellular lipid metabolic process GO:0044255 323 0.098
single organism cell adhesion GO:0098602 156 0.098
Fly
renal system development GO:0072001 225 0.096
Mouse
regulation of vasculogenesis GO:2001212 9 0.096
regulation of nucleoside metabolic process GO:0009118 130 0.095
myeloid cell differentiation GO:0030099 233 0.095
purine containing compound metabolic process GO:0072521 311 0.092
purine ribonucleotide metabolic process GO:0009150 290 0.091
cell migration involved in endocardial cushion formation GO:0003273 3 0.090
regulation of long term synaptic depression GO:1900452 3 0.089
ras protein signal transduction GO:0007265 77 0.087
Zebrafish
cellular nitrogen compound catabolic process GO:0044270 280 0.087
regulation of hippo signaling GO:0035330 1 0.086
glucose homeostasis GO:0042593 128 0.085
regulation of cell motility GO:2000145 236 0.085
anatomical structure homeostasis GO:0060249 145 0.085
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.082
heart growth GO:0060419 45 0.080
heterocycle catabolic process GO:0046700 280 0.077
ribonucleotide metabolic process GO:0009259 291 0.077
purine nucleoside metabolic process GO:0042278 241 0.075
cellular response to erythropoietin GO:0036018 1 0.074
amine metabolic process GO:0009308 45 0.071
gtp metabolic process GO:0046039 144 0.071
glycosyl compound catabolic process GO:1901658 206 0.071
positive regulation of bmp signaling pathway GO:0030513 23 0.069
cardiac chamber morphogenesis GO:0003206 93 0.069
ribonucleoside metabolic process GO:0009119 245 0.069
cell migration involved in coronary angiogenesis GO:0060981 1 0.068
epidermis development GO:0008544 187 0.068
cell cell adhesion GO:0098609 41 0.068
response to peptide GO:1901652 136 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.067
rho protein signal transduction GO:0007266 32 0.067
aromatic compound catabolic process GO:0019439 286 0.067
mapk cascade GO:0000165 281 0.065
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.065
positive regulation of mapk cascade GO:0043410 170 0.065
regulation of organelle organization GO:0033043 289 0.065
regulation of cellular component biogenesis GO:0044087 181 0.065
purine ribonucleoside catabolic process GO:0046130 205 0.064
regulation of cellular catabolic process GO:0031329 242 0.064
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.064
regulation of auditory receptor cell differentiation GO:0045607 4 0.063
regulation of cell activation GO:0050865 289 0.063
regulation of defense response GO:0031347 233 0.062
muscle cell proliferation GO:0033002 52 0.061
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.061
tissue homeostasis GO:0001894 115 0.060
erythropoietin mediated signaling pathway GO:0038162 1 0.060
heart trabecula morphogenesis GO:0061384 26 0.059
regulation of lipoprotein lipase activity GO:0051004 4 0.059
actin filament organization GO:0007015 113 0.058
purine nucleotide metabolic process GO:0006163 302 0.058
regulation of ras gtpase activity GO:0032318 88 0.058
regulation of cardiac cell fate specification GO:2000043 1 0.058
cardiac cell fate specification GO:0060912 2 0.058
Fly
regulation of cell cycle process GO:0010564 160 0.057
regulation of lens epithelial cell proliferation GO:2001109 1 0.056
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.056
morphogenesis of a branching structure GO:0001763 203 0.056
response to organonitrogen compound GO:0010243 246 0.056
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.056
organic cyclic compound catabolic process GO:1901361 295 0.055
nucleotide metabolic process GO:0009117 332 0.055
response to erythropoietin GO:0036017 1 0.054
negative regulation of cellular component organization GO:0051129 194 0.054
regulation of cytokine production GO:0001817 266 0.054
regulation of hormone levels GO:0010817 211 0.054
nucleoside phosphate catabolic process GO:1901292 222 0.053
endodermal cell fate specification GO:0001714 4 0.053
regulation of secretion GO:0051046 274 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.053
regulation of purine nucleotide metabolic process GO:1900542 169 0.053
leukocyte differentiation GO:0002521 342 0.053
nucleoside triphosphate catabolic process GO:0009143 205 0.052
muscle tissue development GO:0060537 308 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.052
t cell activation GO:0042110 289 0.051
ribonucleoside triphosphate metabolic process GO:0009199 220 0.051
cardiac endothelial cell differentiation GO:0003348 4 0.051
multicellular organismal homeostasis GO:0048871 164 0.051
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
regulation of actin cytoskeleton organization GO:0032956 84 0.051
mitral valve morphogenesis GO:0003183 4 0.050
synapse organization GO:0050808 125 0.050
ribose phosphate metabolic process GO:0019693 291 0.050
regulation of system process GO:0044057 200 0.050
cellular response to growth factor stimulus GO:0071363 197 0.050
generation of precursor metabolites and energy GO:0006091 103 0.050
cellular amino acid metabolic process GO:0006520 103 0.049
epithelial cell migration GO:0010631 63 0.048
Zebrafish Fly
homeostasis of number of cells GO:0048872 210 0.048
regulation of cell adhesion GO:0030155 154 0.047
Zebrafish Fly
organonitrogen compound catabolic process GO:1901565 264 0.046
ion transmembrane transport GO:0034220 361 0.046
nitrogen compound transport GO:0071705 271 0.046
cytokine production GO:0001816 319 0.046
guanosine containing compound metabolic process GO:1901068 144 0.046
organonitrogen compound biosynthetic process GO:1901566 192 0.045
energy derivation by oxidation of organic compounds GO:0015980 77 0.045
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.045
cardiac atrium development GO:0003230 24 0.045
response to growth factor GO:0070848 198 0.045
insulin secretion GO:0030073 89 0.044
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.044
endodermal cell fate determination GO:0007493 2 0.044
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.044
negative regulation of nervous system development GO:0051961 156 0.043
epithelial cell proliferation GO:0050673 174 0.043
negative regulation of molecular function GO:0044092 258 0.043
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.043
response to oxygen levels GO:0070482 62 0.043
striated muscle tissue development GO:0014706 293 0.043
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.043
purine containing compound catabolic process GO:0072523 213 0.042
hair cell differentiation GO:0035315 40 0.042
gtp catabolic process GO:0006184 143 0.042
regionalization GO:0003002 337 0.042
Fly
positive regulation of lipoprotein lipase activity GO:0051006 3 0.042
regulation of kinase activity GO:0043549 249 0.042
central nervous system neuron differentiation GO:0021953 162 0.042
Mouse
stem cell development GO:0048864 219 0.041
purine nucleoside catabolic process GO:0006152 205 0.041
regulation of extracellular matrix assembly GO:1901201 2 0.041
osteoclast differentiation GO:0030316 62 0.041
t cell differentiation GO:0030217 174 0.041
septum primum development GO:0003284 4 0.041
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.041
regulation of cell projection organization GO:0031344 206 0.041
Fly
compartment pattern specification GO:0007386 4 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.040
regulation of secretion by cell GO:1903530 249 0.040
lymphocyte differentiation GO:0030098 242 0.040
glycosyl compound metabolic process GO:1901657 246 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.039
positive regulation of protein modification process GO:0031401 299 0.039
regulation of protein kinase activity GO:0045859 232 0.039
cardiac muscle tissue development GO:0048738 130 0.039
lateral inhibition GO:0046331 1 0.039
cellular response to thyroid hormone stimulus GO:0097067 1 0.038
cardiac muscle fiber development GO:0048739 4 0.038
purine nucleoside triphosphate catabolic process GO:0009146 203 0.038
cellular response to stem cell factor stimulus GO:0036216 3 0.038
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.037
positive regulation of nervous system development GO:0051962 221 0.037
tripeptide transport GO:0042939 1 0.037
pro t cell differentiation GO:0002572 3 0.036
cardiac muscle tissue growth GO:0055017 37 0.036
branching morphogenesis of an epithelial tube GO:0048754 159 0.036
ascending aorta morphogenesis GO:0035910 3 0.036
smooth muscle cell chemotaxis GO:0071670 2 0.035
germ cell development GO:0007281 185 0.035
rhythmic process GO:0048511 174 0.035
Fly
wnt signaling pathway GO:0016055 188 0.035
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.035
macrophage colony stimulating factor signaling pathway GO:0038145 2 0.035
circulatory system process GO:0003013 197 0.035
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.034
cardiac ventricle morphogenesis GO:0003208 50 0.034
regulation of lymphocyte differentiation GO:0045619 107 0.033
response to amino acid GO:0043200 37 0.033
response to acid chemical GO:0001101 111 0.033
nephron epithelium development GO:0072009 92 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.032
cardiac atrium morphogenesis GO:0003209 23 0.032
nucleoside catabolic process GO:0009164 206 0.032
guanosine containing compound catabolic process GO:1901069 144 0.032
blood circulation GO:0008015 195 0.032
transmembrane transport GO:0055085 412 0.032
nephron development GO:0072006 109 0.032
nucleotide catabolic process GO:0009166 217 0.032
response to decreased oxygen levels GO:0036293 59 0.032
regulation of mitotic cell cycle GO:0007346 126 0.032
cardiocyte differentiation GO:0035051 87 0.032
Fly
endocardial cell differentiation GO:0060956 4 0.032
regulation of muscle tissue development GO:1901861 97 0.031
b cell differentiation GO:0030183 78 0.031
inner ear receptor cell differentiation GO:0060113 61 0.031
cell fate commitment GO:0045165 210 0.031
Fly
atrial septum primum morphogenesis GO:0003289 3 0.031
regulation of rho gtpase activity GO:0032319 58 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.031
peptide secretion GO:0002790 114 0.031
developmental maturation GO:0021700 193 0.031
regulation of cell cycle GO:0051726 281 0.031
regulation of endothelial cell migration GO:0010594 22 0.031
astrocyte fate commitment GO:0060018 4 0.031
regulation of cytoskeleton organization GO:0051493 122 0.030
organophosphate catabolic process GO:0046434 232 0.030
extracellular matrix organization GO:0030198 147 0.030
synaptic transmission GO:0007268 329 0.030
ascending aorta development GO:0035905 3 0.030
carbohydrate homeostasis GO:0033500 128 0.030
male germ line sex determination GO:0019100 2 0.030
purine nucleotide catabolic process GO:0006195 211 0.030
cellular response to lipid GO:0071396 145 0.030
peptide transport GO:0015833 133 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
renal vesicle induction GO:0072034 3 0.029
striatal medium spiny neuron differentiation GO:0021773 2 0.029
lipid homeostasis GO:0055088 63 0.029
regulation of heart growth GO:0060420 31 0.029
lung alveolus development GO:0048286 45 0.029
retina development in camera type eye GO:0060041 119 0.029
heart valve development GO:0003170 23 0.029
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.029
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 7 0.029
regulation of ras protein signal transduction GO:0046578 114 0.028
Zebrafish
leukocyte mediated immunity GO:0002443 174 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
regulation of cell division GO:0051302 76 0.028
establishment of organelle localization GO:0051656 122 0.028
nucleoside triphosphate metabolic process GO:0009141 230 0.028
negative regulation of glial cell proliferation GO:0060253 4 0.028
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.028
regulation of rho protein signal transduction GO:0035023 71 0.028
endocardial cushion morphogenesis GO:0003203 18 0.028
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.028
regulation of lymphocyte activation GO:0051249 240 0.028
endothelial cell differentiation GO:0045446 41 0.027
mitral valve development GO:0003174 4 0.027
regulation of purine nucleotide catabolic process GO:0033121 122 0.027
extracellular structure organization GO:0043062 148 0.027
axonogenesis GO:0007409 274 0.027
Mouse Worm Fly
kit signaling pathway GO:0038109 3 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
negative regulation of cell development GO:0010721 169 0.027
ribonucleoside catabolic process GO:0042454 206 0.027
sterol homeostasis GO:0055092 45 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.027
dendritic cell cytokine production GO:0002371 3 0.027
spermatid differentiation GO:0048515 115 0.027
regulation of ion transmembrane transport GO:0034765 119 0.027
regulation of cellular response to stress GO:0080135 159 0.027
male gamete generation GO:0048232 285 0.027
metanephric mesenchymal cell migration GO:0035789 2 0.026
skeletal muscle organ development GO:0060538 163 0.026
mesonephric tubule development GO:0072164 94 0.026
Mouse
regulation of membrane potential GO:0042391 192 0.026
regulation of cell migration GO:0030334 219 0.026
wound healing GO:0042060 157 0.026
positive regulation of cytokine production GO:0001819 174 0.026
amide transport GO:0042886 138 0.026
defense response to bacterium GO:0042742 119 0.026
phosphatidylinositol metabolic process GO:0046488 45 0.026
skin development GO:0043588 220 0.025
cellular response to cytokine stimulus GO:0071345 189 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.025
apoptotic signaling pathway GO:0097190 306 0.025
hormone secretion GO:0046879 128 0.025
cell division GO:0051301 120 0.025
regulation of nucleotide catabolic process GO:0030811 122 0.025
aorta morphogenesis GO:0035909 22 0.025
growth involved in heart morphogenesis GO:0003241 4 0.025
regulation of blood circulation GO:1903522 93 0.025
inflammatory response GO:0006954 244 0.024
actin cytoskeleton organization GO:0030036 220 0.024
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.024
negative regulation of immune system process GO:0002683 209 0.024
negative regulation of pathway restricted smad protein phosphorylation GO:0060394 1 0.024
positive regulation of cell death GO:0010942 224 0.024
cellular response to dna damage stimulus GO:0006974 207 0.024
melanocyte migration GO:0097324 2 0.024
organelle localization GO:0051640 179 0.024
epithelium migration GO:0090132 63 0.024
Zebrafish Fly
cell type specific apoptotic process GO:0097285 268 0.024
response to peptide hormone GO:0043434 127 0.024
angiogenesis GO:0001525 201 0.024
Human Zebrafish
regulation of organ growth GO:0046620 61 0.023
cardiac muscle tissue morphogenesis GO:0055008 44 0.023
sensory organ morphogenesis GO:0090596 242 0.023
engulfment of apoptotic cell GO:0043652 3 0.023
cation transport GO:0006812 399 0.023
membrane organization GO:0061024 245 0.023
ribonucleoside triphosphate catabolic process GO:0009203 199 0.023
regulation of actin filament based process GO:0032970 99 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.023
cellular homeostasis GO:0019725 240 0.023
Fly
peptide hormone secretion GO:0030072 109 0.023
inner ear morphogenesis GO:0042472 101 0.023
cellular response to acid chemical GO:0071229 68 0.023
positive regulation of organelle organization GO:0010638 128 0.023
drug catabolic process GO:0042737 2 0.023
erk1 and erk2 cascade GO:0070371 77 0.023
myeloid leukocyte differentiation GO:0002573 119 0.022
sensory perception of sound GO:0007605 97 0.022
female gamete generation GO:0007292 74 0.022
respiratory tube development GO:0030323 167 0.022
blastocyst development GO:0001824 80 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
negative regulation of growth GO:0045926 99 0.022
positive regulation of glutamate receptor signaling pathway GO:1900451 3 0.022
regulation of anatomical structure size GO:0090066 178 0.022
lung development GO:0030324 164 0.022
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.022
mesonephros development GO:0001823 97 0.022
Mouse
negative regulation of cell activation GO:0050866 111 0.022
ear morphogenesis GO:0042471 118 0.022
positive regulation of triglyceride lipase activity GO:0061365 3 0.022
rac protein signal transduction GO:0016601 13 0.022
Zebrafish
negative regulation of protein metabolic process GO:0051248 282 0.021
elastic fiber assembly GO:0048251 4 0.021
positive regulation of insulin secretion GO:0032024 26 0.021
cardiac chamber development GO:0003205 108 0.021
regulation of ion transport GO:0043269 215 0.021
regulation of t cell activation GO:0050863 170 0.021
regulation of myeloid cell differentiation GO:0045637 96 0.021
regulation of blood vessel remodeling GO:0060312 3 0.021
positive regulation of programmed cell death GO:0043068 218 0.021
morphogenesis of embryonic epithelium GO:0016331 159 0.021
cardiac cell development GO:0055006 41 0.021
inositol lipid mediated signaling GO:0048017 41 0.021
recognition of apoptotic cell GO:0043654 3 0.021
habituation GO:0046959 3 0.021
myeloid dendritic cell chemotaxis GO:0002408 2 0.021
gamma delta t cell activation GO:0046629 13 0.021
forebrain development GO:0030900 302 0.021
Mouse
endothelial cell apoptotic process GO:0072577 9 0.021
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.021
regulation of neuron projection development GO:0010975 169 0.020
Fly
respiratory system development GO:0060541 190 0.020
Fly
primary prostatic bud elongation GO:0060516 2 0.020
response to insulin GO:0032868 100 0.020
striated muscle cell proliferation GO:0014855 39 0.020
regulation of response to wounding GO:1903034 189 0.020
muscle cell differentiation GO:0042692 261 0.020
second messenger mediated signaling GO:0019932 73 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.020
organophosphate biosynthetic process GO:0090407 122 0.020
divalent inorganic cation transport GO:0072511 178 0.020
cell migration involved in vasculogenesis GO:0035441 2 0.020
canonical wnt signaling pathway GO:0060070 130 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
metanephric glomerulus morphogenesis GO:0072275 3 0.020
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
positive regulation of dna biosynthetic process GO:2000573 4 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
Mouse
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.019
response to steroid hormone GO:0048545 56 0.019
response to organic cyclic compound GO:0014070 198 0.019
positive regulation of transferase activity GO:0051347 167 0.019
negative regulation of sodium ion transmembrane transport GO:1902306 1 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
negative regulation of neuron differentiation GO:0045665 101 0.019
positive regulation of cell activation GO:0050867 158 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
intracellular protein transport GO:0006886 204 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
mitotic cell cycle GO:0000278 195 0.019
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.018
pro b cell differentiation GO:0002328 10 0.018
negative regulation of organelle organization GO:0010639 90 0.018
peptidyl amino acid modification GO:0018193 336 0.018
multicellular organismal signaling GO:0035637 91 0.018
mitotic cell cycle process GO:1903047 159 0.018
regulation of ion transmembrane transporter activity GO:0032412 54 0.018
regulation of fear response GO:1903365 2 0.018
mitochondrion organization GO:0007005 134 0.018
regulation of metal ion transport GO:0010959 106 0.018
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.018
molting cycle GO:0042303 90 0.018
regulation of erk1 and erk2 cascade GO:0070372 71 0.018
positive regulation of cell migration GO:0030335 109 0.018
pigment biosynthetic process GO:0046148 26 0.018
organelle fission GO:0048285 170 0.018
venous blood vessel development GO:0060841 13 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
regulation of map kinase activity GO:0043405 120 0.018
regulation of peptide hormone secretion GO:0090276 75 0.017
regulation of cardiac muscle tissue development GO:0055024 31 0.017
leukocyte migration GO:0050900 124 0.017
aorta development GO:0035904 23 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
memory GO:0007613 58 0.017
cardiac right ventricle formation GO:0003219 3 0.017
dendritic cell differentiation GO:0097028 26 0.017
blood vessel morphogenesis GO:0048514 285 0.017
Human Zebrafish
digestive system development GO:0055123 200 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
protein catabolic process GO:0030163 221 0.017
cell migration involved in kidney development GO:0035787 3 0.017
cation transmembrane transport GO:0098655 266 0.017
positive regulation of mitotic cell cycle GO:0045931 41 0.017
intrahepatic bile duct development GO:0035622 2 0.017
regulation of protein catabolic process GO:0042176 108 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.017
compound eye development GO:0048749 1 0.017
regulation of fat cell differentiation GO:0045598 81 0.017
drug metabolic process GO:0017144 4 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
telencephalon development GO:0021537 186 0.017
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.016
chromatin organization GO:0006325 206 0.016
erythrocyte differentiation GO:0030218 88 0.016
lung smooth muscle development GO:0061145 2 0.016
cardiac chamber formation GO:0003207 10 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
endodermal digestive tract morphogenesis GO:0061031 4 0.016
stem cell maintenance GO:0019827 130 0.016
protein oligomerization GO:0051259 67 0.016
neuron projection guidance GO:0097485 141 0.016
Mouse Worm Fly
regulation of neuron differentiation GO:0045664 281 0.016
Fly
notch signaling pathway GO:0007219 71 0.016
embryonic digestive tract development GO:0048566 27 0.016
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.016
phospholipid metabolic process GO:0006644 87 0.016
stem cell differentiation GO:0048863 268 0.016
Fly
digestion GO:0007586 40 0.016
regulation of nuclear division GO:0051783 56 0.016
dna biosynthetic process GO:0071897 22 0.016
cellular response to epidermal growth factor stimulus GO:0071364 4 0.016
regulation of t cell differentiation GO:0045580 83 0.016
striated muscle cell development GO:0055002 125 0.016
cytokine production involved in immune response GO:0002367 34 0.016
regulation of mapk cascade GO:0043408 248 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
energy reserve metabolic process GO:0006112 39 0.016
oogenesis GO:0048477 56 0.016
glial cell fate determination GO:0007403 3 0.016
inner cell mass cellular morphogenesis GO:0001828 1 0.016
glycerolipid metabolic process GO:0046486 122 0.016
response to monosaccharide GO:0034284 67 0.016
spermatogenesis GO:0007283 284 0.015
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.015
cellular response to amino acid stimulus GO:0071230 29 0.015
negative regulation of fat cell differentiation GO:0045599 36 0.015
negative regulation of leukocyte differentiation GO:1902106 51 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
negative regulation of wnt signaling pathway GO:0030178 73 0.015
positive regulation of cell development GO:0010720 237 0.015
immune effector process GO:0002252 321 0.015
negative regulation of phosphorylation GO:0042326 166 0.015
regulation of transmembrane transport GO:0034762 128 0.015
bile acid secretion GO:0032782 2 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
cellular response to glucose stimulus GO:0071333 45 0.015
cellular response to insulin stimulus GO:0032869 78 0.015
regulation of androgen receptor signaling pathway GO:0060765 3 0.015
glomerular mesangial cell development GO:0072144 3 0.015
negative regulation of cell projection organization GO:0031345 56 0.015
endothelial cell migration GO:0043542 44 0.015
Zebrafish
negative regulation of cell motility GO:2000146 61 0.015
catecholamine metabolic process GO:0006584 30 0.015
cardiogenic plate morphogenesis GO:0003142 1 0.015
respiratory gaseous exchange GO:0007585 43 0.015
positive regulation of extracellular matrix organization GO:1903055 4 0.015
endocardium formation GO:0060214 4 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.015
synapse assembly GO:0007416 56 0.015
g protein coupled receptor signaling pathway GO:0007186 243 0.015
dna metabolic process GO:0006259 303 0.015
adherens junction assembly GO:0034333 22 0.015
regulation of epithelial cell migration GO:0010632 35 0.015
Fly
regulation of heart contraction GO:0008016 77 0.015
positive regulation of secretion by cell GO:1903532 114 0.015
palate development GO:0060021 76 0.015
negative regulation of protein modification process GO:0031400 163 0.015
chondrocyte hypertrophy GO:0003415 4 0.015

Robo4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025