Mus musculus

18 known processes

Clp1

CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)

(Aliases: Heab,AI462438)

Clp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 5 0.089
mrna metabolic process GO:0016071 84 0.075
cellular amino acid metabolic process GO:0006520 103 0.067
amine metabolic process GO:0009308 45 0.065
myeloid cell differentiation GO:0030099 233 0.065
regulation of cellular amine metabolic process GO:0033238 20 0.064
cellular amine metabolic process GO:0044106 44 0.063
rna splicing GO:0008380 54 0.060
rna processing GO:0006396 105 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
regulation of cellular ketone metabolic process GO:0010565 66 0.050
cellular ketone metabolic process GO:0042180 84 0.048
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
dna metabolic process GO:0006259 303 0.044
leukocyte differentiation GO:0002521 342 0.044
regulation of lymphocyte activation GO:0051249 240 0.043
regulation of cell activation GO:0050865 289 0.042
methylation GO:0032259 134 0.042
nucleotide metabolic process GO:0009117 332 0.042
modification dependent protein catabolic process GO:0019941 133 0.041
cellular response to dna damage stimulus GO:0006974 207 0.040
mrna splicing via spliceosome GO:0000398 43 0.038
negative regulation of apoptotic signaling pathway GO:2001234 104 0.038
mrna processing GO:0006397 63 0.034
modification dependent macromolecule catabolic process GO:0043632 133 0.034
t cell activation GO:0042110 289 0.033
positive regulation of lymphocyte activation GO:0051251 140 0.033
transmission of nerve impulse GO:0019226 76 0.031
protein ubiquitination GO:0016567 171 0.031
peptidyl amino acid modification GO:0018193 336 0.031
negative regulation of protein metabolic process GO:0051248 282 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.030
protein modification by small protein conjugation or removal GO:0070647 207 0.030
regulation of transferase activity GO:0051338 263 0.030
germ cell development GO:0007281 185 0.030
homeostasis of number of cells GO:0048872 210 0.030
rna splicing via transesterification reactions GO:0000375 43 0.029
posttranscriptional regulation of gene expression GO:0010608 155 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
nucleoside phosphate metabolic process GO:0006753 338 0.029
organic cyclic compound catabolic process GO:1901361 295 0.028
macromolecule methylation GO:0043414 120 0.027
organophosphate biosynthetic process GO:0090407 122 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
male gamete generation GO:0048232 285 0.027
small gtpase mediated signal transduction GO:0007264 97 0.026
cellular lipid metabolic process GO:0044255 323 0.026
chromatin organization GO:0006325 206 0.026
camera type eye development GO:0043010 266 0.026
immune effector process GO:0002252 321 0.026
protein modification by small protein conjugation GO:0032446 187 0.026
skeletal system development GO:0001501 356 0.026
synaptic transmission GO:0007268 329 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
nucleotide biosynthetic process GO:0009165 78 0.026
spermatogenesis GO:0007283 284 0.026
dna endoreduplication GO:0042023 4 0.026
regulation of organelle organization GO:0033043 289 0.025
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.025
proteasomal protein catabolic process GO:0010498 98 0.025
blastocyst growth GO:0001832 23 0.025
t cell differentiation GO:0030217 174 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
aromatic compound catabolic process GO:0019439 286 0.025
action potential GO:0001508 78 0.025
dephosphorylation GO:0016311 129 0.024
response to acid chemical GO:0001101 111 0.024
regulation of cellular catabolic process GO:0031329 242 0.024
circulatory system process GO:0003013 197 0.024
regulation of protein kinase activity GO:0045859 232 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
stem cell differentiation GO:0048863 268 0.024
inflammatory response GO:0006954 244 0.024
positive regulation of protein modification process GO:0031401 299 0.023
lymphocyte differentiation GO:0030098 242 0.023
cytoplasmic transport GO:0016482 234 0.023
negative regulation of cellular amine metabolic process GO:0033239 1 0.023
regulation of membrane potential GO:0042391 192 0.023
apoptotic signaling pathway GO:0097190 306 0.023
retina development in camera type eye GO:0060041 119 0.023
organelle fission GO:0048285 170 0.023
multicellular organismal signaling GO:0035637 91 0.023
regulation of leukocyte differentiation GO:1902105 159 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
cellular protein complex assembly GO:0043623 116 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
organelle assembly GO:0070925 177 0.021
regulation of protein catabolic process GO:0042176 108 0.021
blastocyst development GO:0001824 80 0.021
protein methylation GO:0006479 81 0.020
cellular homeostasis GO:0019725 240 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
regulation of kinase activity GO:0043549 249 0.020
neuronal action potential GO:0019228 54 0.020
macromolecule catabolic process GO:0009057 281 0.020
gonad development GO:0008406 141 0.020
ras protein signal transduction GO:0007265 77 0.020
positive regulation of transferase activity GO:0051347 167 0.020
membrane lipid biosynthetic process GO:0046467 32 0.020
transmembrane transport GO:0055085 412 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
myeloid leukocyte differentiation GO:0002573 119 0.019
erythrocyte differentiation GO:0030218 88 0.019
chromatin modification GO:0016568 187 0.019
protein catabolic process GO:0030163 221 0.019
mitotic cell cycle process GO:1903047 159 0.019
leukocyte mediated immunity GO:0002443 174 0.019
positive regulation of cell development GO:0010720 237 0.019
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.019
positive regulation of nervous system development GO:0051962 221 0.019
nicotinamide nucleotide biosynthetic process GO:0019359 4 0.019
cell type specific apoptotic process GO:0097285 268 0.018
blood circulation GO:0008015 195 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
spermatid development GO:0007286 108 0.018
muscle tissue development GO:0060537 308 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
stem cell development GO:0048864 219 0.018
mitotic cell cycle GO:0000278 195 0.018
muscle cell differentiation GO:0042692 261 0.018
spermatid differentiation GO:0048515 115 0.018
regulation of cellular response to stress GO:0080135 159 0.017
positive regulation of leukocyte differentiation GO:1902107 86 0.017
covalent chromatin modification GO:0016569 163 0.017
protein secretion GO:0009306 111 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
regulation of defense response GO:0031347 233 0.017
negative regulation of cell proliferation GO:0008285 296 0.017
peptidyl lysine modification GO:0018205 77 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
nucleoside phosphate biosynthetic process GO:1901293 79 0.017
negative regulation of protein modification process GO:0031400 163 0.017
glycosyl compound metabolic process GO:1901657 246 0.017
developmental maturation GO:0021700 193 0.016
endocytosis GO:0006897 168 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
pyridine nucleotide biosynthetic process GO:0019363 4 0.016
regulation of cell cycle GO:0051726 281 0.016
sensory organ morphogenesis GO:0090596 242 0.016
heterocycle catabolic process GO:0046700 280 0.016
regulation of neuron differentiation GO:0045664 281 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
neural tube formation GO:0001841 108 0.016
mapk cascade GO:0000165 281 0.016
negative regulation of protein catabolic process GO:0042177 36 0.016
regulation of t cell activation GO:0050863 170 0.016
positive regulation of t cell activation GO:0050870 101 0.016
cell division GO:0051301 120 0.016
positive regulation of cell activation GO:0050867 158 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
transcription from rna polymerase iii promoter GO:0006383 3 0.015
striated muscle tissue development GO:0014706 293 0.015
regulation of cellular response to growth factor stimulus GO:0090287 82 0.015
fertilization GO:0009566 127 0.015
regulation of myeloid cell differentiation GO:0045637 96 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
ribonucleoside triphosphate catabolic process GO:0009203 199 0.015
regulation of lymphocyte differentiation GO:0045619 107 0.015
gland development GO:0048732 330 0.015
purine containing compound catabolic process GO:0072523 213 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.015
leukocyte proliferation GO:0070661 172 0.014
cation transmembrane transport GO:0098655 266 0.014
endomembrane system organization GO:0010256 147 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
oocyte axis specification GO:0007309 2 0.014
maturation of 5 8s rrna GO:0000460 1 0.014
response to organic cyclic compound GO:0014070 198 0.014
negative regulation of molecular function GO:0044092 258 0.014
placenta development GO:0001890 140 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
purine containing compound metabolic process GO:0072521 311 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
bone development GO:0060348 120 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
male sex differentiation GO:0046661 109 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of mrna splicing via spliceosome GO:0048024 32 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
myeloid cell homeostasis GO:0002262 114 0.013
digestive system development GO:0055123 200 0.013
oogenesis GO:0048477 56 0.013
regulation of rna splicing GO:0043484 37 0.013
mitotic nuclear division GO:0007067 48 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
positive regulation of kinase activity GO:0033674 155 0.013
embryonic epithelial tube formation GO:0001838 130 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
inner cell mass cell proliferation GO:0001833 15 0.013
cation homeostasis GO:0055080 212 0.013
cell maturation GO:0048469 127 0.013
cation transport GO:0006812 399 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
locomotory behavior GO:0007626 195 0.013
wound healing GO:0042060 157 0.013
asymmetric stem cell division GO:0098722 3 0.013
regionalization GO:0003002 337 0.013
negative regulation of cell development GO:0010721 169 0.013
intracellular protein transport GO:0006886 204 0.013
macromolecular complex disassembly GO:0032984 43 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
stem cell maintenance GO:0019827 130 0.013
lipid biosynthetic process GO:0008610 179 0.013
protein maturation GO:0051604 176 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
embryonic skeletal system development GO:0048706 120 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
intracellular receptor signaling pathway GO:0030522 74 0.012
protein alkylation GO:0008213 81 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
cellular chemical homeostasis GO:0055082 215 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
nucleotide catabolic process GO:0009166 217 0.012
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.012
nuclear division GO:0000280 158 0.012
b cell activation GO:0042113 161 0.012
regulation of mrna processing GO:0050684 41 0.012
nucleoside metabolic process GO:0009116 246 0.012
histone methylation GO:0016571 71 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
axon ensheathment GO:0008366 76 0.012
positive regulation of b cell activation GO:0050871 49 0.012
ribonucleotide catabolic process GO:0009261 208 0.012
blood vessel morphogenesis GO:0048514 285 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
response to growth factor GO:0070848 198 0.012
appendage development GO:0048736 166 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
intracellular mrna localization GO:0008298 4 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
ensheathment of neurons GO:0007272 76 0.012
dendrite development GO:0016358 115 0.012
regulation of alpha beta t cell activation GO:0046634 53 0.012
negative regulation of immune system process GO:0002683 209 0.012
cartilage development GO:0051216 140 0.012
lymphocyte proliferation GO:0046651 164 0.012
response to oxidative stress GO:0006979 123 0.012
respiratory system development GO:0060541 190 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
cellular response to lipid GO:0071396 145 0.012
cell activation involved in immune response GO:0002263 126 0.012
regulation of mapk cascade GO:0043408 248 0.011
oxidation reduction process GO:0055114 342 0.011
cardiac chamber development GO:0003205 108 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
protein localization to organelle GO:0033365 185 0.011
leukocyte apoptotic process GO:0071887 71 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
regulation of hormone levels GO:0010817 211 0.011
ion transmembrane transport GO:0034220 361 0.011
regulation of response to dna damage stimulus GO:2001020 34 0.011
central nervous system neuron differentiation GO:0021953 162 0.011
cell growth GO:0016049 130 0.011
trna processing GO:0008033 11 0.011
skeletal system morphogenesis GO:0048705 203 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
i kappab kinase nf kappab signaling GO:0007249 85 0.011
metal ion homeostasis GO:0055065 189 0.011
protein lipidation GO:0006497 28 0.011
regulation of protein processing GO:0070613 96 0.011
rab protein signal transduction GO:0032482 1 0.011
forebrain development GO:0030900 302 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
negative regulation of protein processing GO:0010955 79 0.011
ncrna processing GO:0034470 26 0.011
leukocyte activation involved in immune response GO:0002366 126 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of secretion GO:0051046 274 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of inflammatory response GO:0050727 147 0.011
b cell differentiation GO:0030183 78 0.011
synapse organization GO:0050808 125 0.011
tube formation GO:0035148 140 0.011
cytokine production GO:0001816 319 0.011
regulation of vacuole organization GO:0044088 4 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
male gonad development GO:0008584 88 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
negative regulation of nervous system development GO:0051961 156 0.011
response to radiation GO:0009314 165 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
renal system development GO:0072001 225 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
negative regulation of neuron differentiation GO:0045665 101 0.011
pharynx development GO:0060465 1 0.011
regulation of leukocyte proliferation GO:0070663 121 0.010
intestinal epithelial structure maintenance GO:0060729 4 0.010
deoxyribonucleoside triphosphate metabolic process GO:0009200 9 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
ossification GO:0001503 216 0.010
rna interference GO:0016246 2 0.010
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.010
histone modification GO:0016570 159 0.010
positive regulation of programmed cell death GO:0043068 218 0.010
regulation of protein maturation GO:1903317 96 0.010
positive regulation of growth GO:0045927 104 0.010
adaptive immune response GO:0002250 155 0.010
response to organonitrogen compound GO:0010243 246 0.010
nitrogen compound transport GO:0071705 271 0.010
regulation of leukocyte mediated immunity GO:0002703 104 0.010
trna wobble base modification GO:0002097 2 0.010
organophosphate catabolic process GO:0046434 232 0.010
regulation of proteolysis GO:0030162 164 0.010
multicellular organismal homeostasis GO:0048871 164 0.010
compound eye development GO:0048749 1 0.010
angiogenesis GO:0001525 201 0.010
myelination GO:0042552 74 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010
membrane organization GO:0061024 245 0.010

Clp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.036
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
hematopoietic system disease DOID:74 0 0.014
musculoskeletal system disease DOID:17 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
primary immunodeficiency disease DOID:612 0 0.010