Mus musculus

73 known processes

Kdm1b

lysine (K)-specific demethylase 1B

(Aliases: Aof1,AI482520,MGC38211,4632428N09Rik)

Kdm1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular lipid metabolic process GO:0044255 323 0.064
nucleoside phosphate metabolic process GO:0006753 338 0.042
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
cellular ketone metabolic process GO:0042180 84 0.040
cellular amino acid metabolic process GO:0006520 103 0.039
organic cyclic compound catabolic process GO:1901361 295 0.038
histone modification GO:0016570 159 0.037
cellular homeostasis GO:0019725 240 0.036
purine nucleotide metabolic process GO:0006163 302 0.036
leukocyte differentiation GO:0002521 342 0.034
nucleoside phosphate catabolic process GO:1901292 222 0.032
nucleotide metabolic process GO:0009117 332 0.031
peptidyl amino acid modification GO:0018193 336 0.031
apoptotic signaling pathway GO:0097190 306 0.030
purine nucleoside metabolic process GO:0042278 241 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
cellular amine metabolic process GO:0044106 44 0.029
macromolecule catabolic process GO:0009057 281 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
ribonucleotide metabolic process GO:0009259 291 0.029
chromatin modification GO:0016568 187 0.029
heterocycle catabolic process GO:0046700 280 0.028
dna metabolic process GO:0006259 303 0.028
immune effector process GO:0002252 321 0.027
aromatic compound catabolic process GO:0019439 286 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
oxidation reduction process GO:0055114 342 0.026
ribonucleotide catabolic process GO:0009261 208 0.025
chromatin organization GO:0006325 206 0.025
amine metabolic process GO:0009308 45 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
covalent chromatin modification GO:0016569 163 0.024
cellular chemical homeostasis GO:0055082 215 0.024
cell type specific apoptotic process GO:0097285 268 0.024
purine containing compound metabolic process GO:0072521 311 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
lipid biosynthetic process GO:0008610 179 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.022
cellular nitrogen compound catabolic process GO:0044270 280 0.022
positive regulation of protein modification process GO:0031401 299 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
microtubule based process GO:0007017 236 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.021
striated muscle tissue development GO:0014706 293 0.021
response to organonitrogen compound GO:0010243 246 0.020
muscle tissue development GO:0060537 308 0.020
g protein coupled receptor signaling pathway GO:0007186 243 0.020
alcohol metabolic process GO:0006066 116 0.020
atp metabolic process GO:0046034 75 0.020
nucleoside metabolic process GO:0009116 246 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
cofactor transport GO:0051181 4 0.019
protein catabolic process GO:0030163 221 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
cation homeostasis GO:0055080 212 0.019
inorganic cation transmembrane transport GO:0098662 207 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
regulation of lipid metabolic process GO:0019216 118 0.018
organophosphate catabolic process GO:0046434 232 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.018
maintenance of location GO:0051235 89 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.017
small gtpase mediated signal transduction GO:0007264 97 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
metal ion homeostasis GO:0055065 189 0.017
response to peptide hormone GO:0043434 127 0.017
lymphocyte differentiation GO:0030098 242 0.017
lipid homeostasis GO:0055088 63 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
purine containing compound catabolic process GO:0072523 213 0.017
sensory perception GO:0007600 245 0.017
nucleotide catabolic process GO:0009166 217 0.017
homeostasis of number of cells GO:0048872 210 0.017
regulation of cytokine production GO:0001817 266 0.016
stem cell development GO:0048864 219 0.016
compound eye development GO:0048749 1 0.016
positive regulation of cellular catabolic process GO:0031331 148 0.016
myeloid cell differentiation GO:0030099 233 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
carbohydrate metabolic process GO:0005975 230 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
fat cell differentiation GO:0045444 160 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
protein modification by small protein conjugation GO:0032446 187 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
organophosphate biosynthetic process GO:0090407 122 0.016
positive regulation of cell development GO:0010720 237 0.015
cytoplasmic transport GO:0016482 234 0.015
regulation of cell activation GO:0050865 289 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
transmembrane transport GO:0055085 412 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
forebrain development GO:0030900 302 0.015
t cell activation GO:0042110 289 0.015
cation transmembrane transport GO:0098655 266 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
intracellular protein transport GO:0006886 204 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
cytokine production GO:0001816 319 0.015
membrane lipid metabolic process GO:0006643 53 0.015
negative regulation of immune system process GO:0002683 209 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
cellular ion homeostasis GO:0006873 165 0.015
nitrogen compound transport GO:0071705 271 0.015
regulation of leukocyte differentiation GO:1902105 159 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
protein ubiquitination GO:0016567 171 0.014
purine nucleoside monophosphate catabolic process GO:0009128 58 0.014
glucose homeostasis GO:0042593 128 0.014
carbohydrate homeostasis GO:0033500 128 0.014
regulation of cell cycle GO:0051726 281 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
response to organic cyclic compound GO:0014070 198 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
nucleoside catabolic process GO:0009164 206 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
skeletal muscle organ development GO:0060538 163 0.014
membrane organization GO:0061024 245 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.013
glycerolipid metabolic process GO:0046486 122 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
anion transport GO:0006820 177 0.013
response to oxidative stress GO:0006979 123 0.013
regulation of protein localization GO:0032880 231 0.013
innate immune response GO:0045087 157 0.013
cellular response to peptide hormone stimulus GO:0071375 92 0.013
t cell differentiation GO:0030217 174 0.013
hindbrain development GO:0030902 128 0.013
purine ribonucleotide catabolic process GO:0009154 208 0.013
response to inorganic substance GO:0010035 96 0.013
adult behavior GO:0030534 135 0.013
chemotaxis GO:0006935 247 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
fatty acid metabolic process GO:0006631 121 0.013
protein localization to membrane GO:0072657 108 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
regulation of hydrolase activity GO:0051336 246 0.013
camera type eye development GO:0043010 266 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
peptidyl lysine acetylation GO:0018394 45 0.013
regulation of dna damage checkpoint GO:2000001 3 0.013
male gamete generation GO:0048232 285 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
neuron death GO:0070997 154 0.013
telencephalon development GO:0021537 186 0.012
regulation of feeding behavior GO:0060259 3 0.012
sensory organ morphogenesis GO:0090596 242 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
respiratory system development GO:0060541 190 0.012
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.012
stem cell differentiation GO:0048863 268 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
positive regulation of defense response GO:0031349 124 0.012
glycoprotein biosynthetic process GO:0009101 89 0.012
dna repair GO:0006281 107 0.012
stem cell maintenance GO:0019827 130 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
protein localization to organelle GO:0033365 185 0.012
response to radiation GO:0009314 165 0.012
axonogenesis GO:0007409 274 0.012
cytokinetic process GO:0032506 2 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regulation of proteolysis GO:0030162 164 0.012
lung development GO:0030324 164 0.012
regulation of homeostatic process GO:0032844 182 0.012
regulation of purine nucleotide catabolic process GO:0033121 122 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
cell activation involved in immune response GO:0002263 126 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.012
nuclear transport GO:0051169 139 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
response to extracellular stimulus GO:0009991 127 0.012
positive regulation of interleukin 8 production GO:0032757 2 0.012
b cell activation GO:0042113 161 0.012
rho protein signal transduction GO:0007266 32 0.011
regulation of organelle organization GO:0033043 289 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
regulation of translation GO:0006417 71 0.011
tissue homeostasis GO:0001894 115 0.011
synaptic transmission GO:0007268 329 0.011
multicellular organism growth GO:0035264 161 0.011
calcium ion homeostasis GO:0055074 127 0.011
mitotic cell cycle GO:0000278 195 0.011
muscle cell differentiation GO:0042692 261 0.011
neural precursor cell proliferation GO:0061351 121 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
negative regulation of synapse assembly GO:0051964 3 0.011
neuron apoptotic process GO:0051402 142 0.011
endocytosis GO:0006897 168 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
regulation of protein catabolic process GO:0042176 108 0.011
response to nutrient levels GO:0031667 109 0.011
adaptive immune response GO:0002250 155 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
digestive system development GO:0055123 200 0.011
cofactor metabolic process GO:0051186 80 0.011
male sex differentiation GO:0046661 109 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
regulation of defense response GO:0031347 233 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
wnt signaling pathway GO:0016055 188 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.010
endomembrane system organization GO:0010256 147 0.010
protein localization to plasma membrane GO:0072659 57 0.010
negative regulation of chromatin silencing GO:0031936 1 0.010
regulation of transferase activity GO:0051338 263 0.010
negative regulation of protein modification process GO:0031400 163 0.010
sequestering of calcium ion GO:0051208 18 0.010
protein targeting GO:0006605 143 0.010
regulation of innate immune response GO:0045088 91 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
anatomical structure homeostasis GO:0060249 145 0.010
protein maturation GO:0051604 176 0.010
atp catabolic process GO:0006200 55 0.010
myeloid cell homeostasis GO:0002262 114 0.010
response to peptide GO:1901652 136 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
ion transmembrane transport GO:0034220 361 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
organic anion transport GO:0015711 137 0.010
response to insulin GO:0032868 100 0.010
cell growth GO:0016049 130 0.010
positive regulation of transferase activity GO:0051347 167 0.010
locomotory behavior GO:0007626 195 0.010
response to growth factor GO:0070848 198 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010

Kdm1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of cellular proliferation DOID:14566 0 0.021
disease of metabolism DOID:0014667 0 0.020
cancer DOID:162 0 0.018
central nervous system disease DOID:331 0 0.015
organ system cancer DOID:0050686 0 0.014
immune system disease DOID:2914 0 0.012