Mus musculus

70 known processes

Clk2

CDC-like kinase 2

(Aliases: AU041688,Tu52)

Clk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.324
entry into host GO:0044409 15 0.301
regulation of reactive oxygen species metabolic process GO:2000377 40 0.297
dna metabolic process GO:0006259 303 0.286
regulation of cellular ketone metabolic process GO:0010565 66 0.264
mrna processing GO:0006397 63 0.245
cellular nitrogen compound catabolic process GO:0044270 280 0.230
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.200
myeloid cell differentiation GO:0030099 233 0.188
chromatin modification GO:0016568 187 0.168
histone modification GO:0016570 159 0.158
aromatic compound catabolic process GO:0019439 286 0.153
cytokine production GO:0001816 319 0.150
positive regulation of dna templated transcription elongation GO:0032786 2 0.139
regulation of cytokine production GO:0001817 266 0.138
mrna 3 end processing GO:0031124 16 0.132
norepinephrine secretion GO:0048243 2 0.114
organic cyclic compound catabolic process GO:1901361 295 0.111
chromatin organization GO:0006325 206 0.110
ribonucleoprotein complex subunit organization GO:0071826 28 0.101
transcription from rna polymerase iii promoter GO:0006383 3 0.097
Yeast
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.092
histone lysine methylation GO:0034968 50 0.091
amine metabolic process GO:0009308 45 0.089
leukocyte differentiation GO:0002521 342 0.088
peptidyl amino acid modification GO:0018193 336 0.085
dna repair GO:0006281 107 0.084
regulation of histone h3 k4 methylation GO:0051569 12 0.083
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.083
epithalamus development GO:0021538 2 0.078
negative regulation of cytokine production GO:0001818 84 0.077
rna processing GO:0006396 105 0.067
Human
reactive oxygen species metabolic process GO:0072593 84 0.067
positive regulation of viral entry into host cell GO:0046598 3 0.067
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
regionalization GO:0003002 337 0.063
regulation of myeloid leukocyte differentiation GO:0002761 58 0.063
monosaccharide metabolic process GO:0005996 106 0.062
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.062
Yeast
cellular ketone metabolic process GO:0042180 84 0.061
cellular amine metabolic process GO:0044106 44 0.060
embryonic skeletal system development GO:0048706 120 0.059
histone methylation GO:0016571 71 0.059
mrna metabolic process GO:0016071 84 0.058
regulation of chromatin modification GO:1903308 57 0.058
protein targeting GO:0006605 143 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.055
heterocycle catabolic process GO:0046700 280 0.055
homeostasis of number of cells GO:0048872 210 0.054
methylation GO:0032259 134 0.053
modification dependent macromolecule catabolic process GO:0043632 133 0.053
carbohydrate biosynthetic process GO:0016051 74 0.051
viral life cycle GO:0019058 36 0.051
myeloid leukocyte differentiation GO:0002573 119 0.050
wnt signaling pathway GO:0016055 188 0.049
histone h4 k16 acetylation GO:0043984 3 0.049
regulation of response to drug GO:2001023 2 0.049
defense response to other organism GO:0098542 197 0.048
regulation of carbohydrate biosynthetic process GO:0043255 40 0.048
purine nucleoside triphosphate metabolic process GO:0009144 226 0.048
histone acetylation GO:0016573 41 0.048
immune effector process GO:0002252 321 0.047
regulation of myeloid cell differentiation GO:0045637 96 0.046
axis elongation involved in somitogenesis GO:0090245 4 0.045
internal protein amino acid acetylation GO:0006475 42 0.044
urogenital system development GO:0001655 261 0.044
regulation of histone methylation GO:0031060 30 0.044
defense response to virus GO:0051607 68 0.043
cellular amino acid metabolic process GO:0006520 103 0.042
negative regulation of cell proliferation GO:0008285 296 0.041
pigmentation GO:0043473 71 0.041
kidney development GO:0001822 213 0.041
synaptic transmission GO:0007268 329 0.039
regulation of protein localization GO:0032880 231 0.039
stem cell maintenance GO:0019827 130 0.039
histone h3 k4 trimethylation GO:0080182 5 0.038
peptidyl lysine methylation GO:0018022 29 0.038
regulation of anatomical structure size GO:0090066 178 0.037
innate immune response GO:0045087 157 0.037
response to retinoic acid GO:0032526 56 0.037
actin cytoskeleton organization GO:0030036 220 0.036
positive regulation of defense response GO:0031349 124 0.035
macromolecule catabolic process GO:0009057 281 0.035
peptidyl lysine modification GO:0018205 77 0.035
movement in host environment GO:0052126 15 0.035
rhythmic process GO:0048511 174 0.034
regulation of neuron differentiation GO:0045664 281 0.034
mitochondrion organization GO:0007005 134 0.034
covalent chromatin modification GO:0016569 163 0.033
regulation of actin nucleation GO:0051125 4 0.033
skeletal system development GO:0001501 356 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
regulation of cellular component size GO:0032535 121 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
epithelial tube morphogenesis GO:0060562 303 0.032
viral entry into host cell GO:0046718 15 0.032
catecholamine secretion GO:0050432 15 0.032
internal peptidyl lysine acetylation GO:0018393 42 0.032
renal system development GO:0072001 225 0.032
entry into other organism involved in symbiotic interaction GO:0051828 15 0.032
circadian rhythm GO:0007623 114 0.031
regulation of organelle organization GO:0033043 289 0.031
oligodendrocyte differentiation GO:0048709 53 0.030
habenula development GO:0021986 2 0.030
membrane organization GO:0061024 245 0.030
peptidyl tyrosine phosphorylation GO:0018108 143 0.030
glucose metabolic process GO:0006006 92 0.030
regulation of cell division GO:0051302 76 0.029
negative regulation of viral transcription GO:0032897 3 0.029
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.029
endoderm development GO:0007492 45 0.028
metal ion homeostasis GO:0055065 189 0.028
immune response regulating signaling pathway GO:0002764 125 0.028
rna splicing GO:0008380 54 0.028
Human
positive regulation of apoptotic process GO:0043065 217 0.028
cell division GO:0051301 120 0.028
protein acylation GO:0043543 64 0.028
cellular response to dna damage stimulus GO:0006974 207 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
positive regulation of cell death GO:0010942 224 0.027
rna 3 end processing GO:0031123 20 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
regulation of mrna processing GO:0050684 41 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
intracellular receptor signaling pathway GO:0030522 74 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
regulation of cellular catabolic process GO:0031329 242 0.026
cellular homeostasis GO:0019725 240 0.026
compound eye development GO:0048749 1 0.026
cytoplasmic transport GO:0016482 234 0.026
viral gene expression GO:0019080 3 0.026
carbohydrate metabolic process GO:0005975 230 0.026
mitotic cell cycle process GO:1903047 159 0.026
macromolecule methylation GO:0043414 120 0.025
ribonucleotide catabolic process GO:0009261 208 0.025
positive regulation of neuron differentiation GO:0045666 141 0.025
germ cell development GO:0007281 185 0.025
axonogenesis GO:0007409 274 0.025
neural tube formation GO:0001841 108 0.025
digestive tract development GO:0048565 190 0.025
regulation of homeostatic process GO:0032844 182 0.025
histone h4 acetylation GO:0043967 10 0.025
gland development GO:0048732 330 0.024
mrna splicing via spliceosome GO:0000398 43 0.024
endocrine system development GO:0035270 98 0.024
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.024
purine containing compound metabolic process GO:0072521 311 0.024
regulation of organ morphogenesis GO:2000027 144 0.024
extrinsic apoptotic signaling pathway GO:0097191 126 0.024
exocytosis GO:0006887 121 0.024
regulation of interleukin 6 production GO:0032675 55 0.024
response to acid chemical GO:0001101 111 0.024
cytokine metabolic process GO:0042107 71 0.024
norepinephrine transport GO:0015874 2 0.024
cation transport GO:0006812 399 0.024
cytokine biosynthetic process GO:0042089 68 0.024
nucleoside triphosphate metabolic process GO:0009141 230 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
regulation of defense response GO:0031347 233 0.023
establishment of planar polarity GO:0001736 28 0.023
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.023
interaction with host GO:0051701 22 0.023
establishment of tissue polarity GO:0007164 28 0.023
positive regulation of myeloid cell differentiation GO:0045639 43 0.023
intracellular protein transport GO:0006886 204 0.023
mitotic cell cycle GO:0000278 195 0.022
erythrocyte differentiation GO:0030218 88 0.022
morphogenesis of a polarized epithelium GO:0001738 37 0.022
positive regulation of leukocyte differentiation GO:1902107 86 0.022
protein modification by small protein conjugation or removal GO:0070647 207 0.022
protein methylation GO:0006479 81 0.022
nucleotide metabolic process GO:0009117 332 0.022
negative regulation of interleukin 6 production GO:0032715 17 0.022
retrograde transport endosome to golgi GO:0042147 2 0.022
regulation of leukocyte differentiation GO:1902105 159 0.021
embryonic skeletal system morphogenesis GO:0048704 91 0.021
lung cell differentiation GO:0060479 30 0.021
regulation of cell activation GO:0050865 289 0.021
cellular chemical homeostasis GO:0055082 215 0.021
gtp metabolic process GO:0046039 144 0.021
regulation of asymmetric cell division GO:0009786 4 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.021
positive regulation of cellular component biogenesis GO:0044089 94 0.021
pattern recognition receptor signaling pathway GO:0002221 47 0.020
cellular hyperosmotic salinity response GO:0071475 0 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
epithelial tube formation GO:0072175 130 0.020
somitogenesis GO:0001756 69 0.020
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.020
regulation of cytokine biosynthetic process GO:0042035 59 0.020
action potential GO:0001508 78 0.019
respiratory tube development GO:0030323 167 0.019
organophosphate biosynthetic process GO:0090407 122 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
nitrogen compound transport GO:0071705 271 0.019
positive regulation of innate immune response GO:0045089 80 0.019
rhombomere morphogenesis GO:0021593 2 0.019
peripheral nervous system development GO:0007422 53 0.019
sequestering of metal ion GO:0051238 19 0.019
oligodendrocyte development GO:0014003 20 0.019
positive regulation of neuron projection development GO:0010976 79 0.019
gliogenesis GO:0042063 141 0.019
cellular protein complex assembly GO:0043623 116 0.018
regulation of response to biotic stimulus GO:0002831 38 0.018
regulation of mrna metabolic process GO:1903311 43 0.018
nuclear division GO:0000280 158 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
divalent inorganic cation homeostasis GO:0072507 138 0.018
gastrulation GO:0007369 116 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
negative regulation of chromatin silencing GO:0031936 1 0.018
embryonic viscerocranium morphogenesis GO:0048703 8 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
histone h3 k4 methylation GO:0051568 23 0.018
ossification GO:0001503 216 0.018
glucose homeostasis GO:0042593 128 0.018
myeloid cell homeostasis GO:0002262 114 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
developmental maturation GO:0021700 193 0.018
protein ubiquitination GO:0016567 171 0.018
negative regulation of protein targeting to membrane GO:0090315 1 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
lung development GO:0030324 164 0.018
glycolytic process GO:0006096 20 0.018
divalent inorganic cation transport GO:0072511 178 0.017
actin filament based movement GO:0030048 23 0.017
somite development GO:0061053 81 0.017
digestive system development GO:0055123 200 0.017
regulation of rna splicing GO:0043484 37 0.017
Human
negative regulation of protein modification process GO:0031400 163 0.017
skeletal system morphogenesis GO:0048705 203 0.017
cellular response to starvation GO:0009267 57 0.017
protein polymerization GO:0051258 57 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.017
protein alkylation GO:0008213 81 0.017
negative regulation of defense response GO:0031348 77 0.017
peptidyl lysine acetylation GO:0018394 45 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
positive regulation of apoptotic signaling pathway GO:2001235 95 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
stem cell fate specification GO:0048866 3 0.016
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.016
asymmetric stem cell division GO:0098722 3 0.016
regulation of cell cycle process GO:0010564 160 0.016
histone deubiquitination GO:0016578 2 0.016
negative regulation of immune system process GO:0002683 209 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
peptidyl tyrosine modification GO:0018212 145 0.016
nucleotide catabolic process GO:0009166 217 0.016
regulation of innate immune response GO:0045088 91 0.015
cellular ion homeostasis GO:0006873 165 0.015
positive regulation of cell development GO:0010720 237 0.015
positive regulation of actin nucleation GO:0051127 3 0.015
regulation of nucleotide catabolic process GO:0030811 122 0.015
proprioception GO:0019230 4 0.015
metanephric loop of henle development GO:0072236 4 0.015
positive regulation of organelle organization GO:0010638 128 0.015
immune response activating signal transduction GO:0002757 116 0.015
membrane fusion GO:0061025 38 0.015
activation of immune response GO:0002253 138 0.015
regulation of chromatin organization GO:1902275 57 0.015
negative regulation of immune effector process GO:0002698 55 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.015
regulation of secretion GO:0051046 274 0.015
protein secretion GO:0009306 111 0.015
regulation of secretion by cell GO:1903530 249 0.015
plasma membrane organization GO:0007009 90 0.015
spermatogenesis GO:0007283 284 0.015
humoral immune response GO:0006959 57 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
asymmetric neuroblast division GO:0055059 1 0.014
somatic stem cell maintenance GO:0035019 47 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
tumor necrosis factor production GO:0032640 50 0.014
regulation of cell cycle GO:0051726 281 0.014
response to light stimulus GO:0009416 135 0.014
sequestering of calcium ion GO:0051208 18 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
dna alkylation GO:0006305 43 0.014
regulation of muscle tissue development GO:1901861 97 0.014
viral transcription GO:0019083 3 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
regulation of transcription during meiosis GO:0051037 1 0.014
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
toll like receptor signaling pathway GO:0002224 38 0.014
regulation of histone modification GO:0031056 56 0.014
positive regulation of nervous system development GO:0051962 221 0.014
protein localization to organelle GO:0033365 185 0.014
protein homotrimerization GO:0070207 4 0.013
ascending thin limb development GO:0072021 2 0.013
digestive tract morphogenesis GO:0048546 147 0.013
schwann cell differentiation GO:0014037 26 0.013
regulation of ral protein signal transduction GO:0032485 4 0.013
gonad development GO:0008406 141 0.013
telomere capping GO:0016233 4 0.013
interleukin 6 production GO:0032635 58 0.013
regulation of defense response to virus GO:0050688 18 0.013
midbrain development GO:0030901 35 0.013
regulation of cell motility GO:2000145 236 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
regulation of toll like receptor signaling pathway GO:0034121 20 0.013
negative regulation of multi organism process GO:0043901 68 0.013
t cell activation GO:0042110 289 0.013
primary neural tube formation GO:0014020 95 0.013
actin filament organization GO:0007015 113 0.013
tube closure GO:0060606 91 0.013
gene silencing by mirna GO:0035195 10 0.013
regulation of ion homeostasis GO:2000021 64 0.013
divalent metal ion transport GO:0070838 172 0.013
regulation of hormone levels GO:0010817 211 0.013
regulation of membrane potential GO:0042391 192 0.013
response to organic cyclic compound GO:0014070 198 0.013
protein processing GO:0016485 163 0.013
tissue homeostasis GO:0001894 115 0.013
purine containing compound catabolic process GO:0072523 213 0.013
carbohydrate homeostasis GO:0033500 128 0.012
memory GO:0007613 58 0.012
cation homeostasis GO:0055080 212 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
stem cell differentiation GO:0048863 268 0.012
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.012
cellular response to nutrient levels GO:0031669 64 0.012
negative regulation of organelle organization GO:0010639 90 0.012
hexose metabolic process GO:0019318 98 0.012
male gamete generation GO:0048232 285 0.012
positive regulation of cytokine production GO:0001819 174 0.012
stem cell division GO:0017145 30 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
negative regulation of tumor necrosis factor production GO:0032720 17 0.011
defense response to bacterium GO:0042742 119 0.011
diencephalon development GO:0021536 63 0.011
interferon beta production GO:0032608 16 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
regulation of protein kinase activity GO:0045859 232 0.011
cellular response to carbohydrate stimulus GO:0071322 50 0.011
positive regulation of synaptic plasticity GO:0031915 4 0.011
positive regulation of gtp catabolic process GO:0033126 85 0.011
response to radiation GO:0009314 165 0.011
Human
cellular response to extracellular stimulus GO:0031668 81 0.011
nephron epithelium development GO:0072009 92 0.011
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.011
actin filament polymerization GO:0030041 44 0.011
adaptive immune response GO:0002250 155 0.011
response to nutrient levels GO:0031667 109 0.011
schwann cell development GO:0014044 22 0.011
entry into host cell GO:0030260 15 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
neuron death GO:0070997 154 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
cellular response to glucose stimulus GO:0071333 45 0.011
chemotaxis GO:0006935 247 0.011
regulation of ossification GO:0030278 112 0.011
rac protein signal transduction GO:0016601 13 0.011
response to organonitrogen compound GO:0010243 246 0.011
negative regulation of cell development GO:0010721 169 0.011
intracellular distribution of mitochondria GO:0048312 1 0.011
gluconeogenesis GO:0006094 39 0.011
neural crest cell differentiation GO:0014033 54 0.011
anatomical structure homeostasis GO:0060249 145 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
response to starvation GO:0042594 65 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
response to drug GO:0042493 75 0.011
segmentation GO:0035282 93 0.011
regulation of tumor necrosis factor production GO:0032680 49 0.011
development of primary sexual characteristics GO:0045137 143 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
leukocyte mediated immunity GO:0002443 174 0.011
neural precursor cell proliferation GO:0061351 121 0.011
transmembrane transport GO:0055085 412 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
negative regulation of cellular protein metabolic process GO:0032269 247 0.010
positive regulation of protein modification process GO:0031401 299 0.010
pharynx development GO:0060465 1 0.010
defense response to gram negative bacterium GO:0050829 28 0.010
stem cell development GO:0048864 219 0.010
regulation of t cell proliferation GO:0042129 92 0.010
sensory perception GO:0007600 245 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
maintenance of location GO:0051235 89 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.010
cellular response to hexose stimulus GO:0071331 47 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
peptidyl serine modification GO:0018209 83 0.010
Mouse

Clk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
x linked disease DOID:0050735 0 0.023