Mus musculus

21 known processes

Clk3

CDC-like kinase 3

(Aliases: MGC103028,MGC36552,AI256811)

Clk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.164
Yeast
chromatin modification GO:0016568 187 0.156
histone modification GO:0016570 159 0.143
protein ubiquitination GO:0016567 171 0.124
cellular ketone metabolic process GO:0042180 84 0.123
Mouse
intra golgi vesicle mediated transport GO:0006891 1 0.116
male gamete generation GO:0048232 285 0.109
dna metabolic process GO:0006259 303 0.107
regulation of cellular ketone metabolic process GO:0010565 66 0.095
Mouse
regionalization GO:0003002 337 0.095
chromatin organization GO:0006325 206 0.094
transcription from rna polymerase iii promoter GO:0006383 3 0.083
Yeast
protein modification by small protein conjugation GO:0032446 187 0.078
dna repair GO:0006281 107 0.066
covalent chromatin modification GO:0016569 163 0.063
cytoplasmic transport GO:0016482 234 0.057
cellular macromolecule catabolic process GO:0044265 206 0.056
positive regulation of cellular amine metabolic process GO:0033240 5 0.048
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.046
cellular amine metabolic process GO:0044106 44 0.046
regulation of anatomical structure size GO:0090066 178 0.045
amine metabolic process GO:0009308 45 0.045
membrane fusion GO:0061025 38 0.044
positive regulation of cellular catabolic process GO:0031331 148 0.043
protein modification by small protein conjugation or removal GO:0070647 207 0.042
regulation of reactive oxygen species metabolic process GO:2000377 40 0.042
negative regulation of cell proliferation GO:0008285 296 0.042
response to acid chemical GO:0001101 111 0.041
Mouse
protein dealkylation GO:0008214 13 0.041
regulation of cellular catabolic process GO:0031329 242 0.040
cellular homeostasis GO:0019725 240 0.039
retrograde transport endosome to golgi GO:0042147 2 0.039
aromatic compound catabolic process GO:0019439 286 0.039
cellular response to dna damage stimulus GO:0006974 207 0.038
cellular amino acid metabolic process GO:0006520 103 0.035
modification dependent macromolecule catabolic process GO:0043632 133 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
small gtpase mediated signal transduction GO:0007264 97 0.034
heterocycle catabolic process GO:0046700 280 0.034
modification dependent protein catabolic process GO:0019941 133 0.034
asymmetric stem cell division GO:0098722 3 0.034
positive regulation of nucleotide catabolic process GO:0030813 88 0.034
regulation of mapk cascade GO:0043408 248 0.033
organelle localization GO:0051640 179 0.033
cellular protein catabolic process GO:0044257 155 0.032
cytokine production GO:0001816 319 0.032
protein demethylation GO:0006482 13 0.032
cellular chemical homeostasis GO:0055082 215 0.032
neuron apoptotic process GO:0051402 142 0.031
germ cell development GO:0007281 185 0.031
regulation of cell cycle process GO:0010564 160 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
exocytosis GO:0006887 121 0.030
actin cytoskeleton organization GO:0030036 220 0.029
ras protein signal transduction GO:0007265 77 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
histone demethylation GO:0016577 13 0.028
methylation GO:0032259 134 0.027
maintenance of location GO:0051235 89 0.027
regulation of binding GO:0051098 111 0.027
peptidyl tyrosine phosphorylation GO:0018108 143 0.026
mitotic cytokinesis GO:0000281 4 0.026
positive regulation of transferase activity GO:0051347 167 0.026
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
positive regulation of cell development GO:0010720 237 0.026
negative regulation of phosphate metabolic process GO:0045936 184 0.026
apoptotic signaling pathway GO:0097190 306 0.026
spermatogenesis GO:0007283 284 0.026
endomembrane system organization GO:0010256 147 0.026
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.025
oocyte construction GO:0007308 2 0.025
negative regulation of cellular component organization GO:0051129 194 0.025
muscle tissue development GO:0060537 308 0.025
protein autophosphorylation GO:0046777 61 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
mrna metabolic process GO:0016071 84 0.024
regulation of cell cycle GO:0051726 281 0.024
regulation of protein kinase activity GO:0045859 232 0.024
muscle cell differentiation GO:0042692 261 0.024
ubiquitin dependent protein catabolic process GO:0006511 129 0.024
digestive system development GO:0055123 200 0.024
establishment of organelle localization GO:0051656 122 0.024
regulation of cellular component biogenesis GO:0044087 181 0.023
mitotic cell cycle GO:0000278 195 0.023
vesicle organization GO:0016050 60 0.023
small molecule biosynthetic process GO:0044283 132 0.023
mapk cascade GO:0000165 281 0.023
regulation of hydrolase activity GO:0051336 246 0.023
forebrain development GO:0030900 302 0.023
regulation of cytokine production GO:0001817 266 0.023
placenta development GO:0001890 140 0.022
protein catabolic process GO:0030163 221 0.022
neuron death GO:0070997 154 0.022
histone lysine demethylation GO:0070076 13 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.022
negative regulation of intracellular signal transduction GO:1902532 167 0.022
glycosyl compound catabolic process GO:1901658 206 0.022
asymmetric neuroblast division GO:0055059 1 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
response to topologically incorrect protein GO:0035966 25 0.022
pole plasm assembly GO:0007315 2 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
regulation of cytoskeleton organization GO:0051493 122 0.021
peptidyl amino acid modification GO:0018193 336 0.021
cell type specific apoptotic process GO:0097285 268 0.021
central nervous system neuron differentiation GO:0021953 162 0.021
regulation of protein complex assembly GO:0043254 83 0.021
negative regulation of growth GO:0045926 99 0.021
response to organonitrogen compound GO:0010243 246 0.021
regulation of wnt signaling pathway GO:0030111 123 0.021
defense response to other organism GO:0098542 197 0.021
camera type eye development GO:0043010 266 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
protein secretion GO:0009306 111 0.020
regulation of transferase activity GO:0051338 263 0.020
cell division GO:0051301 120 0.020
regulation of cellular response to stress GO:0080135 159 0.020
tube closure GO:0060606 91 0.020
protein localization to organelle GO:0033365 185 0.020
regulation of organelle organization GO:0033043 289 0.020
purine ribonucleotide metabolic process GO:0009150 290 0.020
entry into host GO:0044409 15 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
endocytosis GO:0006897 168 0.020
striated muscle tissue development GO:0014706 293 0.020
entry into other organism involved in symbiotic interaction GO:0051828 15 0.020
lymphocyte mediated immunity GO:0002449 139 0.019
sequestering of calcium ion GO:0051208 18 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
immune effector process GO:0002252 321 0.019
cellular lipid metabolic process GO:0044255 323 0.019
leukocyte mediated immunity GO:0002443 174 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
inclusion body assembly GO:0070841 3 0.019
purine containing compound metabolic process GO:0072521 311 0.019
oocyte axis specification GO:0007309 2 0.019
nitrogen compound transport GO:0071705 271 0.019
rna processing GO:0006396 105 0.019
Human
skeletal muscle organ development GO:0060538 163 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
cellular protein complex assembly GO:0043623 116 0.018
regulation of stress activated mapk cascade GO:0032872 69 0.018
gonad development GO:0008406 141 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
regulation of apoptotic signaling pathway GO:2001233 197 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
regulation of neuron differentiation GO:0045664 281 0.017
regulation of cell projection organization GO:0031344 206 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
mitotic cell cycle process GO:1903047 159 0.017
macromolecule catabolic process GO:0009057 281 0.017
regulation of rna splicing GO:0043484 37 0.017
Human
regulation of nucleoside metabolic process GO:0009118 130 0.017
blastocyst development GO:0001824 80 0.017
segmentation GO:0035282 93 0.017
b cell activation GO:0042113 161 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
cell adhesion GO:0007155 329 0.017
membrane organization GO:0061024 245 0.017
wnt signaling pathway GO:0016055 188 0.017
regulation of homeostatic process GO:0032844 182 0.017
immune response regulating signaling pathway GO:0002764 125 0.017
stem cell proliferation GO:0072089 117 0.017
neurotransmitter transport GO:0006836 76 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
myeloid cell homeostasis GO:0002262 114 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
nucleotide metabolic process GO:0009117 332 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
innate immune response GO:0045087 157 0.016
regulation of cell activation GO:0050865 289 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
myosin filament assembly GO:0031034 2 0.016
regulation of secretion GO:0051046 274 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
metal ion homeostasis GO:0055065 189 0.016
positive regulation of protein modification process GO:0031401 299 0.016
regulation of kinase activity GO:0043549 249 0.016
inner cell mass cell proliferation GO:0001833 15 0.016
cation transport GO:0006812 399 0.016
regulation of nucleotide catabolic process GO:0030811 122 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
axonogenesis GO:0007409 274 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
regulation of neuron death GO:1901214 134 0.015
demethylation GO:0070988 23 0.015
compound eye development GO:0048749 1 0.015
protein modification by small protein removal GO:0070646 21 0.015
myeloid leukocyte differentiation GO:0002573 119 0.015
action potential GO:0001508 78 0.015
positive regulation of defense response GO:0031349 124 0.015
ribonucleotide catabolic process GO:0009261 208 0.015
dna replication GO:0006260 52 0.015
cdp choline pathway GO:0006657 2 0.015
multicellular organismal signaling GO:0035637 91 0.015
positive regulation of kinase activity GO:0033674 155 0.014
positive regulation of interleukin 8 production GO:0032757 2 0.014
tumor necrosis factor production GO:0032640 50 0.014
peptidyl serine modification GO:0018209 83 0.014
Mouse
purine nucleoside metabolic process GO:0042278 241 0.014
epithelial tube formation GO:0072175 130 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
glucose homeostasis GO:0042593 128 0.014
lymphocyte differentiation GO:0030098 242 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
ribonucleoside metabolic process GO:0009119 245 0.014
intracellular protein transport GO:0006886 204 0.014
gtp metabolic process GO:0046039 144 0.014
regulation of metal ion transport GO:0010959 106 0.014
negative regulation of immune system process GO:0002683 209 0.014
transmission of nerve impulse GO:0019226 76 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
protein methylation GO:0006479 81 0.014
cellular response to biotic stimulus GO:0071216 92 0.014
regulation of dna binding GO:0051101 39 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
organonitrogen compound catabolic process GO:1901565 264 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
negative regulation of molecular function GO:0044092 258 0.014
canonical wnt signaling pathway GO:0060070 130 0.014
organelle assembly GO:0070925 177 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
negative regulation of cytokine production GO:0001818 84 0.014
regulation of synaptic vesicle exocytosis GO:2000300 11 0.014
positive regulation of gtpase activity GO:0043547 85 0.013
positive regulation of gtp catabolic process GO:0033126 85 0.013
plasma membrane organization GO:0007009 90 0.013
t cell activation GO:0042110 289 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
Mouse
nucleoside catabolic process GO:0009164 206 0.013
regulation of interleukin 8 production GO:0032677 3 0.013
ribonucleoprotein complex subunit organization GO:0071826 28 0.013
locomotory behavior GO:0007626 195 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
spermatid development GO:0007286 108 0.013
poly a mrna export from nucleus GO:0016973 4 0.013
renal system development GO:0072001 225 0.013
gtp catabolic process GO:0006184 143 0.013
nucleotide catabolic process GO:0009166 217 0.013
striated muscle myosin thick filament assembly GO:0071688 1 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
intracellular receptor signaling pathway GO:0030522 74 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
regulation of actin filament based process GO:0032970 99 0.013
multicellular organism growth GO:0035264 161 0.013
positive regulation of nervous system development GO:0051962 221 0.013
negative regulation of protein modification process GO:0031400 163 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
neuron migration GO:0001764 122 0.013
regulation of protein binding GO:0043393 60 0.012
intracellular mrna localization GO:0008298 4 0.012
positive regulation of cell adhesion GO:0045785 80 0.012
carbohydrate metabolic process GO:0005975 230 0.012
Mouse
gland development GO:0048732 330 0.012
positive regulation of protein catabolic process GO:0045732 60 0.012
actin filament polymerization GO:0030041 44 0.012
purine containing compound catabolic process GO:0072523 213 0.012
defense response to bacterium GO:0042742 119 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
neuronal action potential GO:0019228 54 0.012
lipid biosynthetic process GO:0008610 179 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
regulation of neuron projection development GO:0010975 169 0.012
immune response activating signal transduction GO:0002757 116 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.012
Mouse
regulation of protein catabolic process GO:0042176 108 0.012
cellular response to topologically incorrect protein GO:0035967 25 0.012
regulation of cellular component size GO:0032535 121 0.012
immunoglobulin mediated immune response GO:0016064 69 0.012
stem cell differentiation GO:0048863 268 0.012
synaptic transmission GO:0007268 329 0.012
negative regulation of cell development GO:0010721 169 0.012
protein polymerization GO:0051258 57 0.012
regulation of fat cell differentiation GO:0045598 81 0.012
regulation of protein localization GO:0032880 231 0.012
nuclear transport GO:0051169 139 0.012
cation homeostasis GO:0055080 212 0.011
development of primary sexual characteristics GO:0045137 143 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
divalent inorganic cation transport GO:0072511 178 0.011
tube formation GO:0035148 140 0.011
sequestering of metal ion GO:0051238 19 0.011
microtubule based process GO:0007017 236 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
urogenital system development GO:0001655 261 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
spermatid differentiation GO:0048515 115 0.011
regulation of membrane potential GO:0042391 192 0.011
establishment of synaptic vesicle localization GO:0097480 57 0.011
sensory perception GO:0007600 245 0.011
nucleic acid transport GO:0050657 18 0.011
transition metal ion homeostasis GO:0055076 54 0.011
regulation of viral transcription GO:0046782 3 0.011
carbohydrate homeostasis GO:0033500 128 0.011
purine nucleotide catabolic process GO:0006195 211 0.011
regulation of body fluid levels GO:0050878 162 0.011
positive regulation of secretion GO:0051047 130 0.011
cytokinetic process GO:0032506 2 0.011
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.011
protein localization to membrane GO:0072657 108 0.011
jnk cascade GO:0007254 72 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
organelle fission GO:0048285 170 0.011
regulation of synaptic vesicle transport GO:1902803 13 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
neural tube formation GO:0001841 108 0.011
macromolecule methylation GO:0043414 120 0.011
positive regulation of cell death GO:0010942 224 0.011
regulation of synaptic vesicle priming GO:0010807 4 0.011
multi multicellular organism process GO:0044706 109 0.011
purine nucleoside triphosphate metabolic process GO:0009144 226 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.011
regulation of secretion by cell GO:1903530 249 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
actin filament organization GO:0007015 113 0.011
positive regulation of actin nucleation GO:0051127 3 0.011
activation of immune response GO:0002253 138 0.011
negative regulation of wnt signaling pathway GO:0030178 73 0.011
vesicle fusion GO:0006906 16 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
neural tube development GO:0021915 160 0.011
male meiosis i GO:0007141 16 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
cell maturation GO:0048469 127 0.010
appendage development GO:0048736 166 0.010
regulation of t cell activation GO:0050863 170 0.010
glycosyl compound metabolic process GO:1901657 246 0.010
sensory organ morphogenesis GO:0090596 242 0.010
kidney development GO:0001822 213 0.010
nuclear division GO:0000280 158 0.010
dendrite development GO:0016358 115 0.010
ensheathment of neurons GO:0007272 76 0.010
photoreceptor cell differentiation GO:0046530 52 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.010
morphogenesis of a polarized epithelium GO:0001738 37 0.010
digestive tract development GO:0048565 190 0.010
androgen receptor signaling pathway GO:0030521 8 0.010
protein oligomerization GO:0051259 67 0.010
transmembrane transport GO:0055085 412 0.010
nucleoside triphosphate metabolic process GO:0009141 230 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.010
regulation of defense response GO:0031347 233 0.010
leukocyte proliferation GO:0070661 172 0.010

Clk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.015
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014
immune system disease DOID:2914 0 0.012