Mus musculus

11 known processes

Atp12a

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

(Aliases: Atp1al1,MGC124416,HKalpha2,cHKA)

Atp12a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.195
oxidation reduction process GO:0055114 342 0.148
inorganic cation transmembrane transport GO:0098662 207 0.147
Mouse Rat Worm Fly
amine metabolic process GO:0009308 45 0.143
cation transport GO:0006812 399 0.131
Mouse Rat Worm Fly
cellular ketone metabolic process GO:0042180 84 0.129
regulation of cellular amino acid metabolic process GO:0006521 5 0.124
regulation of neuron differentiation GO:0045664 281 0.118
cellular amine metabolic process GO:0044106 44 0.111
regulation of cellular ketone metabolic process GO:0010565 66 0.105
transmembrane transport GO:0055085 412 0.081
Mouse Rat Worm Fly
regulation of cell cycle GO:0051726 281 0.075
protein modification by small protein conjugation or removal GO:0070647 207 0.074
cation homeostasis GO:0055080 212 0.073
epidermis development GO:0008544 187 0.068
inorganic ion transmembrane transport GO:0098660 234 0.064
Mouse Rat Worm Fly
synaptic transmission GO:0007268 329 0.064
Mouse Fly
peptidyl amino acid modification GO:0018193 336 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.059
placenta development GO:0001890 140 0.054
regulation of secretion by cell GO:1903530 249 0.054
kidney development GO:0001822 213 0.047
developmental maturation GO:0021700 193 0.047
regulation of neuron projection development GO:0010975 169 0.046
cellular carbohydrate metabolic process GO:0044262 119 0.045
regulation of lipid metabolic process GO:0019216 118 0.045
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.044
mitotic cell cycle GO:0000278 195 0.044
hormone metabolic process GO:0042445 86 0.044
Mouse
muscle tissue development GO:0060537 308 0.044
myotube differentiation GO:0014902 105 0.042
protein processing GO:0016485 163 0.041
ion transmembrane transport GO:0034220 361 0.041
Mouse Rat Worm Fly
skin development GO:0043588 220 0.041
ear development GO:0043583 200 0.040
cytokine production GO:0001816 319 0.039
organic hydroxy compound metabolic process GO:1901615 203 0.039
negative regulation of protein metabolic process GO:0051248 282 0.039
regulation of cell projection organization GO:0031344 206 0.039
regulation of secretion GO:0051046 274 0.039
anion transport GO:0006820 177 0.038
cellular lipid metabolic process GO:0044255 323 0.038
protein modification by small protein conjugation GO:0032446 187 0.038
regulation of protein maturation GO:1903317 96 0.038
cation transmembrane transport GO:0098655 266 0.037
Mouse Rat Worm Fly
negative regulation of molecular function GO:0044092 258 0.037
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
muscle cell differentiation GO:0042692 261 0.036
urogenital system development GO:0001655 261 0.036
regulation of cell activation GO:0050865 289 0.036
positive regulation of nervous system development GO:0051962 221 0.035
camera type eye development GO:0043010 266 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.034
small molecule biosynthetic process GO:0044283 132 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
regulation of organelle organization GO:0033043 289 0.033
monocarboxylic acid metabolic process GO:0032787 191 0.033
carbohydrate homeostasis GO:0033500 128 0.033
protein maturation GO:0051604 176 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.033
positive regulation of protein modification process GO:0031401 299 0.032
spermatogenesis GO:0007283 284 0.032
Mouse
regulation of cell cycle process GO:0010564 160 0.032
regulation of protein localization GO:0032880 231 0.032
purine containing compound metabolic process GO:0072521 311 0.031
Mouse Rat Worm Fly
adult behavior GO:0030534 135 0.030
Mouse Fly
lipid biosynthetic process GO:0008610 179 0.030
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
Mouse Rat Worm Fly
transmission of nerve impulse GO:0019226 76 0.029
male gamete generation GO:0048232 285 0.029
Mouse
glucose homeostasis GO:0042593 128 0.029
metal ion homeostasis GO:0055065 189 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
negative regulation of immune system process GO:0002683 209 0.028
protein ubiquitination GO:0016567 171 0.027
negative regulation of protein processing GO:0010955 79 0.027
positive regulation of cell development GO:0010720 237 0.027
renal system development GO:0072001 225 0.027
regulation of organ morphogenesis GO:2000027 144 0.027
carboxylic acid transport GO:0046942 100 0.027
sensory perception of mechanical stimulus GO:0050954 107 0.026
Fly
sensory perception GO:0007600 245 0.026
Fly
skeletal muscle organ development GO:0060538 163 0.026
organic acid transport GO:0015849 101 0.026
regulation of hormone levels GO:0010817 211 0.026
Mouse
sensory organ morphogenesis GO:0090596 242 0.026
regulation of myeloid cell differentiation GO:0045637 96 0.026
regulation of transferase activity GO:0051338 263 0.026
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.026
carbohydrate biosynthetic process GO:0016051 74 0.025
peptidyl serine modification GO:0018209 83 0.025
negative regulation of cell proliferation GO:0008285 296 0.025
sulfur compound metabolic process GO:0006790 100 0.025
regulation of defense response GO:0031347 233 0.025
extracellular structure organization GO:0043062 148 0.025
regulation of anatomical structure size GO:0090066 178 0.024
Mouse Fly
hydrogen ion transmembrane transport GO:1902600 25 0.024
Mouse Rat
positive regulation of cell cycle GO:0045787 92 0.024
maintenance of location GO:0051235 89 0.024
regulation of ion transport GO:0043269 215 0.024
Mouse
endomembrane system organization GO:0010256 147 0.024
connective tissue development GO:0061448 179 0.024
extracellular matrix organization GO:0030198 147 0.024
sensory perception of sound GO:0007605 97 0.023
Fly
skeletal system development GO:0001501 356 0.023
cellular homeostasis GO:0019725 240 0.023
Mouse
lymphocyte differentiation GO:0030098 242 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.023
wound healing GO:0042060 157 0.023
alcohol metabolic process GO:0006066 116 0.022
negative regulation of cell cycle GO:0045786 123 0.022
regulation of kinase activity GO:0043549 249 0.022
cellular response to cytokine stimulus GO:0071345 189 0.022
positive regulation of secretion GO:0051047 130 0.022
calcium ion transport GO:0006816 159 0.022
leukocyte differentiation GO:0002521 342 0.021
muscle contraction GO:0006936 101 0.021
Mouse Worm
regulation of establishment of protein localization GO:0070201 181 0.021
asymmetric stem cell division GO:0098722 3 0.021
negative regulation of peptidase activity GO:0010466 46 0.021
ribonucleoside metabolic process GO:0009119 245 0.021
Mouse Rat Worm Fly
organonitrogen compound catabolic process GO:1901565 264 0.021
Mouse Rat Worm Fly
organic anion transport GO:0015711 137 0.021
apoptotic signaling pathway GO:0097190 306 0.020
negative regulation of nervous system development GO:0051961 156 0.020
macromolecule catabolic process GO:0009057 281 0.020
Worm
posttranscriptional regulation of gene expression GO:0010608 155 0.020
blood circulation GO:0008015 195 0.020
Mouse
protein catabolic process GO:0030163 221 0.020
Worm
hair follicle development GO:0001942 85 0.019
regulation of transmembrane transport GO:0034762 128 0.019
small gtpase mediated signal transduction GO:0007264 97 0.019
potassium ion homeostasis GO:0055075 4 0.019
chemotaxis GO:0006935 247 0.019
nucleotide metabolic process GO:0009117 332 0.019
Mouse Rat Worm Fly
carboxylic acid biosynthetic process GO:0046394 86 0.019
cognition GO:0050890 149 0.019
Mouse
action potential GO:0001508 78 0.019
Worm
peptide metabolic process GO:0006518 46 0.019
positive regulation of organelle organization GO:0010638 128 0.019
positive regulation of transferase activity GO:0051347 167 0.019
negative regulation of protein maturation GO:1903318 79 0.019
tube formation GO:0035148 140 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
Mouse Rat Worm Fly
ossification GO:0001503 216 0.019
mitotic cell cycle process GO:1903047 159 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
cellular metal ion homeostasis GO:0006875 151 0.019
Mouse
negative regulation of proteolysis GO:0045861 74 0.018
positive regulation of mitotic cell cycle GO:0045931 41 0.018
regulation of proteolysis GO:0030162 164 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
Mouse Rat Worm Fly
cellular protein complex assembly GO:0043623 116 0.018
response to metal ion GO:0010038 47 0.018
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
Mouse Rat Worm Fly
muscle cell development GO:0055001 133 0.018
cellular response to peptide GO:1901653 92 0.018
synapse organization GO:0050808 125 0.018
Fly
divalent inorganic cation transport GO:0072511 178 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
Mouse Rat Worm Fly
cellular response to external stimulus GO:0071496 88 0.018
negative regulation of mitotic cell cycle GO:0045930 58 0.018
homeostasis of number of cells GO:0048872 210 0.018
aromatic compound catabolic process GO:0019439 286 0.018
Mouse Rat Worm Fly
negative regulation of endopeptidase activity GO:0010951 44 0.018
neuronal action potential GO:0019228 54 0.018
retina development in camera type eye GO:0060041 119 0.017
cell maturation GO:0048469 127 0.017
inner ear morphogenesis GO:0042472 101 0.017
microtubule cytoskeleton organization GO:0000226 157 0.017
regulation of cell motility GO:2000145 236 0.017
response to organonitrogen compound GO:0010243 246 0.017
cardiac muscle tissue development GO:0048738 130 0.017
regulation of cellular component size GO:0032535 121 0.017
regulation of skeletal muscle fiber development GO:0048742 36 0.017
cochlea development GO:0090102 35 0.017
mitotic nuclear division GO:0007067 48 0.017
neutral lipid metabolic process GO:0006638 57 0.017
chromatin organization GO:0006325 206 0.017
negative regulation of hydrolase activity GO:0051346 71 0.017
forebrain development GO:0030900 302 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
regulation of cell adhesion GO:0030155 154 0.016
inflammatory response GO:0006954 244 0.016
regulation of cell migration GO:0030334 219 0.016
cellular modified amino acid metabolic process GO:0006575 63 0.016
muscle fiber development GO:0048747 76 0.016
inorganic anion transport GO:0015698 43 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
Mouse Rat Worm Fly
regulation of cellular component biogenesis GO:0044087 181 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
fat cell differentiation GO:0045444 160 0.016
carbohydrate metabolic process GO:0005975 230 0.016
learning GO:0007612 98 0.016
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.016
Mouse Rat Worm Fly
notch signaling pathway GO:0007219 71 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
Mouse Rat Worm Fly
epithelial cell development GO:0002064 159 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
organelle fission GO:0048285 170 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
cell cell junction organization GO:0045216 72 0.016
Fly
steroid biosynthetic process GO:0006694 47 0.016
Mouse
cellular alcohol biosynthetic process GO:0044108 3 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
mitochondrion organization GO:0007005 134 0.016
single organism cell adhesion GO:0098602 156 0.016
protein localization to organelle GO:0033365 185 0.016
positive regulation of nucleotide metabolic process GO:0045981 114 0.016
striated muscle tissue development GO:0014706 293 0.016
rho protein signal transduction GO:0007266 32 0.016
negative regulation of cellular component organization GO:0051129 194 0.015
multicellular organismal signaling GO:0035637 91 0.015
compound eye development GO:0048749 1 0.015
axonogenesis GO:0007409 274 0.015
cellular chemical homeostasis GO:0055082 215 0.015
Mouse
positive regulation of secretion by cell GO:1903532 114 0.015
regulation of endopeptidase activity GO:0052548 89 0.015
organelle localization GO:0051640 179 0.015
chromatin modification GO:0016568 187 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
Mouse Rat Worm Fly
myeloid leukocyte differentiation GO:0002573 119 0.015
regulation of cytokine production GO:0001817 266 0.015
negative regulation of cell development GO:0010721 169 0.015
cellular potassium ion transport GO:0071804 43 0.015
Mouse Rat Worm Fly
negative regulation of protein modification process GO:0031400 163 0.015
regulation of muscle tissue development GO:1901861 97 0.015
cell type specific apoptotic process GO:0097285 268 0.015
mapk cascade GO:0000165 281 0.015
response to extracellular stimulus GO:0009991 127 0.015
cellular response to dna damage stimulus GO:0006974 207 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
response to peptide hormone GO:0043434 127 0.015
cellular response to organonitrogen compound GO:0071417 145 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
Mouse Rat Worm Fly
fatty acid metabolic process GO:0006631 121 0.014
regulation of systemic arterial blood pressure GO:0003073 61 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
regulation of thyroid hormone generation GO:2000609 4 0.014
odontogenesis of dentin containing tooth GO:0042475 66 0.014
regulation of peptide hormone secretion GO:0090276 75 0.014
establishment of tissue polarity GO:0007164 28 0.014
regulation of hydrolase activity GO:0051336 246 0.014
regulation of homeostatic process GO:0032844 182 0.014
skeletal muscle fiber development GO:0048741 58 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
Mouse Rat Worm Fly
t cell activation GO:0042110 289 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
regulation of response to wounding GO:1903034 189 0.014
heart process GO:0003015 94 0.014
Mouse
nuclear division GO:0000280 158 0.014
sodium ion transmembrane transport GO:0035725 49 0.014
Mouse Worm Fly
nitrogen compound transport GO:0071705 271 0.014
single organismal cell cell adhesion GO:0016337 131 0.014
photoreceptor cell development GO:0042461 40 0.014
gonad development GO:0008406 141 0.014
regulation of membrane potential GO:0042391 192 0.013
Mouse Worm
glycerolipid metabolic process GO:0046486 122 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.013
Mouse Rat Worm Fly
regulation of cell cycle phase transition GO:1901987 77 0.013
molting cycle GO:0042303 90 0.013
intracellular protein transport GO:0006886 204 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
response to peptide GO:1901652 136 0.013
muscle system process GO:0003012 141 0.013
Mouse Worm
gliogenesis GO:0042063 141 0.013
positive regulation of myeloid cell differentiation GO:0045639 43 0.013
positive regulation of cell activation GO:0050867 158 0.013
regulation of phospholipase a2 activity GO:0032429 3 0.013
mechanoreceptor differentiation GO:0042490 67 0.013
lateral inhibition GO:0046331 1 0.013
anion transmembrane transport GO:0098656 71 0.013
cellular response to monosaccharide stimulus GO:0071326 47 0.013
regulation of peptidase activity GO:0052547 96 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
Mouse Rat Worm Fly
homotypic cell cell adhesion GO:0034109 28 0.013
response to inorganic substance GO:0010035 96 0.013
Rat
cellular response to peptide hormone stimulus GO:0071375 92 0.013
regulation of neuron death GO:1901214 134 0.013
modification dependent macromolecule catabolic process GO:0043632 133 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
regulation of nuclear division GO:0051783 56 0.012
regulation of striated muscle cell differentiation GO:0051153 81 0.012
immune effector process GO:0002252 321 0.012
regulation of protein transport GO:0051223 163 0.012
response to growth factor GO:0070848 198 0.012
negative regulation of neuron death GO:1901215 98 0.012
myotube cell development GO:0014904 60 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
regulation of body fluid levels GO:0050878 162 0.012
calcium ion homeostasis GO:0055074 127 0.012
Mouse
nucleocytoplasmic transport GO:0006913 139 0.012
organic acid biosynthetic process GO:0016053 86 0.012
multi multicellular organism process GO:0044706 109 0.012
cell division GO:0051301 120 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.012
negative regulation of neuron apoptotic process GO:0043524 92 0.012
response to oxidative stress GO:0006979 123 0.012
regulation of t cell activation GO:0050863 170 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
nephron development GO:0072006 109 0.012
positive regulation of leukocyte differentiation GO:1902107 86 0.012
ovulation cycle GO:0042698 59 0.012
negative regulation of cytokine production GO:0001818 84 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
Mouse Rat Worm Fly
stem cell proliferation GO:0072089 117 0.011
divalent inorganic cation homeostasis GO:0072507 138 0.011
Mouse
defecation GO:0030421 1 0.011
peptide hormone secretion GO:0030072 109 0.011
neuron apoptotic process GO:0051402 142 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
neuron projection guidance GO:0097485 141 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
Fly
negative regulation of hormone biosynthetic process GO:0032353 4 0.011
Mouse
negative regulation of response to wounding GO:1903035 77 0.011
excretion GO:0007588 22 0.011
blastocyst development GO:0001824 80 0.011
jak stat cascade GO:0007259 42 0.011
positive regulation of cell death GO:0010942 224 0.011
rhythmic process GO:0048511 174 0.011
microtubule based process GO:0007017 236 0.011
development of primary sexual characteristics GO:0045137 143 0.011
hair cycle GO:0042633 90 0.011
asymmetric neuroblast division GO:0055059 1 0.011
sensory perception of light stimulus GO:0050953 54 0.011
cellular response to nutrient levels GO:0031669 64 0.011
response to radiation GO:0009314 165 0.011
Mouse
learning or memory GO:0007611 148 0.011
Mouse
tendon cell differentiation GO:0035990 4 0.011
hormone secretion GO:0046879 128 0.011
sulfur compound biosynthetic process GO:0044272 37 0.011
purine nucleoside metabolic process GO:0042278 241 0.011
Mouse Rat Worm Fly
regulation of peptidyl serine phosphorylation GO:0033135 39 0.011
respiratory system process GO:0003016 25 0.011
Mouse
cell cell adhesion GO:0098609 41 0.011
memory GO:0007613 58 0.011
Mouse
protein oligomerization GO:0051259 67 0.011
nuclear transport GO:0051169 139 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
epithelial tube formation GO:0072175 130 0.011
dendrite development GO:0016358 115 0.011
negative regulation of organelle organization GO:0010639 90 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
protein secretion GO:0009306 111 0.011
male sex differentiation GO:0046661 109 0.011
mitochondrion distribution GO:0048311 4 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
ear morphogenesis GO:0042471 118 0.010
cellular divalent inorganic cation homeostasis GO:0072503 127 0.010
Mouse
innate immune response GO:0045087 157 0.010
regulation of system process GO:0044057 200 0.010
Mouse Worm
regulation of hormone metabolic process GO:0032350 15 0.010
Mouse
cellular amide metabolic process GO:0043603 58 0.010
positive regulation of ion transport GO:0043270 65 0.010
monocarboxylic acid transport GO:0015718 44 0.010
regulation of peptide secretion GO:0002791 77 0.010
peptide transport GO:0015833 133 0.010
negative regulation of intracellular signal transduction GO:1902532 167 0.010
regulation of carbohydrate metabolic process GO:0006109 75 0.010
regulation of protein processing GO:0070613 96 0.010
potassium ion transmembrane transport GO:0071805 43 0.010
Mouse Rat Worm Fly
pyruvate transport GO:0006848 2 0.010
response to starvation GO:0042594 65 0.010
cardiocyte differentiation GO:0035051 87 0.010
respiratory system development GO:0060541 190 0.010
Fly

Atp12a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
central nervous system disease DOID:331 0 0.019
neurodegenerative disease DOID:1289 0 0.017
inherited metabolic disorder DOID:655 0 0.013
disease of metabolism DOID:0014667 0 0.013
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012
bone disease DOID:0080001 0 0.011