Mus musculus

0 known processes

Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

(Aliases: Sglt2)

Slc5a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hexose transmembrane transport GO:0035428 7 1.000
Rat
anion transport GO:0006820 177 0.955
chloride transmembrane transport GO:1902476 24 0.952
chloride transport GO:0006821 32 0.930
inorganic anion transmembrane transport GO:0098661 29 0.883
inorganic anion transport GO:0015698 43 0.854
hydrogen ion transmembrane transport GO:1902600 25 0.853
ion transmembrane transport GO:0034220 361 0.836
Rat
glucose transport GO:0015758 56 0.814
Rat
kidney development GO:0001822 213 0.702
organic anion transport GO:0015711 137 0.675
fluid transport GO:0042044 14 0.669
response to osmotic stress GO:0006970 21 0.631
transmembrane transport GO:0055085 412 0.508
Rat
vitamin transport GO:0051180 10 0.507
cation transport GO:0006812 399 0.492
Rat
inorganic ion transmembrane transport GO:0098660 234 0.472
Rat
sodium ion transport GO:0006814 73 0.419
Rat
inorganic cation transmembrane transport GO:0098662 207 0.412
Rat
urea transport GO:0015840 4 0.399
renal system process GO:0003014 48 0.399
monosaccharide transport GO:0015749 58 0.384
Rat
proton transport GO:0015992 35 0.345
hypotonic response GO:0006971 3 0.336
carbohydrate transmembrane transport GO:0034219 10 0.336
Rat
urea transmembrane transport GO:0071918 2 0.327
carbohydrate transport GO:0008643 62 0.327
Rat
cation transmembrane transport GO:0098655 266 0.321
Rat
urogenital system development GO:0001655 261 0.318
monocarboxylic acid metabolic process GO:0032787 191 0.306
spermatogenesis GO:0007283 284 0.306
dehydroascorbic acid transport GO:0070837 3 0.279
nitrogen compound transport GO:0071705 271 0.276
establishment of blood nerve barrier GO:0008065 3 0.275
monovalent inorganic cation homeostasis GO:0055067 33 0.260
renal sodium ion transport GO:0003096 2 0.251
small molecule biosynthetic process GO:0044283 132 0.211
eye photoreceptor cell differentiation GO:0001754 41 0.200
photoreceptor cell differentiation GO:0046530 52 0.199
kidney epithelium development GO:0072073 121 0.196
immune response in mucosal associated lymphoid tissue GO:0002386 2 0.194
nephron epithelium development GO:0072009 92 0.174
neuronal action potential GO:0019228 54 0.173
central nervous system neuron development GO:0021954 67 0.172
carnitine transmembrane transport GO:1902603 3 0.167
carboxylic acid transport GO:0046942 100 0.157
response to fructose GO:0009750 2 0.155
anion transmembrane transport GO:0098656 71 0.151
multicellular organism growth GO:0035264 161 0.148
organic acid transport GO:0015849 101 0.141
retina development in camera type eye GO:0060041 119 0.140
bile acid and bile salt transport GO:0015721 5 0.139
pons development GO:0021548 13 0.138
regulation of cellular ph GO:0030641 12 0.137
water transport GO:0006833 12 0.132
cellular response to nutrient levels GO:0031669 64 0.113
carboxylic acid biosynthetic process GO:0046394 86 0.111
kidney morphogenesis GO:0060993 83 0.110
renal tubule development GO:0061326 87 0.107
cellular response to extracellular stimulus GO:0031668 81 0.107
response to peptide hormone GO:0043434 127 0.107
cellular response to fructose stimulus GO:0071332 2 0.106
amino acid betaine transport GO:0015838 3 0.104
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.104
renal system development GO:0072001 225 0.101
locomotory behavior GO:0007626 195 0.099
auditory receptor cell differentiation GO:0042491 37 0.098
organic hydroxy compound metabolic process GO:1901615 203 0.097
hexose transport GO:0008645 56 0.097
Rat
retina vasculature development in camera type eye GO:0061298 17 0.094
metencephalon development GO:0022037 89 0.093
negative regulation of stem cell maintenance GO:1902455 4 0.092
amino acid betaine metabolic process GO:0006577 7 0.090
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.089
cofactor metabolic process GO:0051186 80 0.089
response to acid chemical GO:0001101 111 0.086
cochlear nucleus development GO:0021747 4 0.085
regulation of ion transmembrane transporter activity GO:0032412 54 0.083
hydrogen transport GO:0006818 35 0.082
transcytosis GO:0045056 5 0.080
transmission of nerve impulse GO:0019226 76 0.079
regulation of membrane potential GO:0042391 192 0.076
amino acid transport GO:0006865 61 0.076
cellular response to external stimulus GO:0071496 88 0.074
amylopectin metabolic process GO:2000896 1 0.071
regulation of intracellular ph GO:0051453 11 0.070
epithelial cell development GO:0002064 159 0.069
regulation of blood pressure GO:0008217 93 0.069
retinal cell programmed cell death GO:0046666 8 0.068
sensory perception of light stimulus GO:0050953 54 0.067
intestinal absorption GO:0050892 13 0.067
dicarboxylic acid transport GO:0006835 29 0.063
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.063
cation homeostasis GO:0055080 212 0.058
metanephric ascending thin limb development GO:0072218 2 0.057
bicarbonate transport GO:0015701 7 0.056
regulation of transmembrane transport GO:0034762 128 0.054
multicellular organismal signaling GO:0035637 91 0.054
fat cell differentiation GO:0045444 160 0.053
cellular ketone metabolic process GO:0042180 84 0.052
amylopectin biosynthetic process GO:0010021 1 0.051
excretion GO:0007588 22 0.050
cellular homeostasis GO:0019725 240 0.050
cellular ion homeostasis GO:0006873 165 0.049
regulation of metal ion transport GO:0010959 106 0.048
nephron development GO:0072006 109 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.046
camera type eye development GO:0043010 266 0.045
regulation of ph GO:0006885 26 0.045
cellular response to monosaccharide stimulus GO:0071326 47 0.044
exploration behavior GO:0035640 21 0.043
response to peptide GO:1901652 136 0.043
regulation of wnt signaling pathway GO:0030111 123 0.043
lipid biosynthetic process GO:0008610 179 0.043
organic acid biosynthetic process GO:0016053 86 0.042
fat soluble vitamin biosynthetic process GO:0042362 4 0.042
glycosyl compound metabolic process GO:1901657 246 0.042
urate transport GO:0015747 1 0.042
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.041
hepatoblast differentiation GO:0061017 2 0.041
carnitine transport GO:0015879 3 0.040
pigment biosynthetic process GO:0046148 26 0.040
sensory organ morphogenesis GO:0090596 242 0.040
distal tubule development GO:0072017 8 0.039
developmental growth involved in morphogenesis GO:0060560 138 0.038
hindbrain development GO:0030902 128 0.038
mesonephric duct morphogenesis GO:0072180 4 0.036
visual perception GO:0007601 52 0.036
cellular amine metabolic process GO:0044106 44 0.036
divalent metal ion transport GO:0070838 172 0.036
histamine transport GO:0051608 2 0.035
epidermis development GO:0008544 187 0.034
cellular response to osmotic stress GO:0071470 7 0.034
metanephric loop of henle development GO:0072236 4 0.034
regulation of secretion GO:0051046 274 0.033
peptidyl amino acid modification GO:0018193 336 0.033
regulation of transferase activity GO:0051338 263 0.032
monoamine transport GO:0015844 33 0.031
retina morphogenesis in camera type eye GO:0060042 45 0.031
nephron tubule development GO:0072080 84 0.031
nephron morphogenesis GO:0072028 69 0.031
axon ensheathment GO:0008366 76 0.031
metanephric thick ascending limb development GO:0072233 2 0.031
insulin secretion GO:0030073 89 0.031
intracellular protein transport GO:0006886 204 0.030
developmental programmed cell death GO:0010623 41 0.030
neural retina development GO:0003407 41 0.029
metanephros development GO:0001656 79 0.029
regulation of ion homeostasis GO:2000021 64 0.029
organic hydroxy compound transport GO:0015850 93 0.028
response to oxidative stress GO:0006979 123 0.028
cellular modified amino acid metabolic process GO:0006575 63 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
gonad development GO:0008406 141 0.026
amine metabolic process GO:0009308 45 0.026
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.026
response to light stimulus GO:0009416 135 0.026
divalent inorganic cation transport GO:0072511 178 0.026
cellular hypotonic response GO:0071476 3 0.026
cellular response to organonitrogen compound GO:0071417 145 0.025
glial cell differentiation GO:0010001 131 0.025
response to starvation GO:0042594 65 0.025
thick ascending limb development GO:0072023 2 0.025
hair cell differentiation GO:0035315 40 0.025
cellular response to peptide GO:1901653 92 0.025
limb development GO:0060173 166 0.024
ascending thin limb development GO:0072021 2 0.024
response to organic cyclic compound GO:0014070 198 0.024
c21 steroid hormone biosynthetic process GO:0006700 3 0.024
mammary gland epithelium development GO:0061180 65 0.024
regulation of hormone levels GO:0010817 211 0.024
ensheathment of neurons GO:0007272 76 0.024
regulation of peptide secretion GO:0002791 77 0.024
potassium ion transmembrane transport GO:0071805 43 0.024
response to water deprivation GO:0009414 1 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
response to monosaccharide GO:0034284 67 0.023
renal tubule morphogenesis GO:0061333 72 0.023
cellular response to peptide hormone stimulus GO:0071375 92 0.023
response to nutrient levels GO:0031667 109 0.023
pyramidal neuron differentiation GO:0021859 9 0.023
peptidyl serine phosphorylation GO:0018105 74 0.022
cellular response to carbohydrate stimulus GO:0071322 50 0.022
placenta development GO:0001890 140 0.022
carbohydrate derivative biosynthetic process GO:1901137 183 0.022
regulation of homeostatic process GO:0032844 182 0.022
organ or tissue specific immune response GO:0002251 13 0.022
regulation of protein transport GO:0051223 163 0.022
peptide transport GO:0015833 133 0.022
monocarboxylic acid biosynthetic process GO:0072330 61 0.021
monocarboxylic acid transport GO:0015718 44 0.021
positive regulation of apoptotic signaling pathway GO:2001235 95 0.021
camera type eye photoreceptor cell differentiation GO:0060219 15 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
l amino acid transport GO:0015807 32 0.021
axonogenesis GO:0007409 274 0.021
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
regulation of actin filament based process GO:0032970 99 0.021
pigment metabolic process GO:0042440 32 0.020
response to water GO:0009415 1 0.020
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.020
liver development GO:0001889 66 0.020
cellular amino acid metabolic process GO:0006520 103 0.020
apoptotic process involved in development GO:1902742 28 0.020
negative regulation of neuron apoptotic process GO:0043524 92 0.020
skin development GO:0043588 220 0.020
response to insulin GO:0032868 100 0.019
wnt signaling pathway GO:0016055 188 0.019
cellular response to glucose starvation GO:0042149 5 0.019
potassium ion homeostasis GO:0055075 4 0.019
progesterone metabolic process GO:0042448 4 0.019
auditory receptor cell development GO:0060117 20 0.019
positive regulation of apoptotic process GO:0043065 217 0.019
male gamete generation GO:0048232 285 0.019
regulation of peptide transport GO:0090087 91 0.019
regulation of potassium ion transport GO:0043266 16 0.019
nucleoside triphosphate metabolic process GO:0009141 230 0.018
morphogenesis of a branching structure GO:0001763 203 0.018
regulation of kinase activity GO:0043549 249 0.018
reactive oxygen species metabolic process GO:0072593 84 0.018
nephron epithelium morphogenesis GO:0072088 68 0.018
response to growth factor GO:0070848 198 0.017
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.017
protein targeting GO:0006605 143 0.017
regulation of ion transmembrane transport GO:0034765 119 0.017
cellular response to starvation GO:0009267 57 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
cell junction assembly GO:0034329 52 0.017
negative regulation of protein transport GO:0051224 46 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
sulfur compound metabolic process GO:0006790 100 0.017
metal ion homeostasis GO:0055065 189 0.017
regulation of pancreatic juice secretion GO:0090186 4 0.017
synaptic transmission GO:0007268 329 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
cellular response to abiotic stimulus GO:0071214 56 0.017
cellular response to insulin stimulus GO:0032869 78 0.016
cell substrate adhesion GO:0031589 130 0.016
peptidyl tyrosine phosphorylation GO:0018108 143 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
regulation of secretion by cell GO:1903530 249 0.016
mechanoreceptor differentiation GO:0042490 67 0.016
positive regulation of cell death GO:0010942 224 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
positive regulation of potassium ion transport GO:0043268 3 0.016
neurotransmitter transport GO:0006836 76 0.016
epithelial tube formation GO:0072175 130 0.016
protein autophosphorylation GO:0046777 61 0.016
cofactor biosynthetic process GO:0051188 41 0.015
cognition GO:0050890 149 0.015
negative regulation of hormone metabolic process GO:0032351 4 0.015
limb morphogenesis GO:0035108 149 0.015
neural nucleus development GO:0048857 22 0.015
regulation of peptide hormone secretion GO:0090276 75 0.015
synaptic vesicle localization GO:0097479 59 0.015
chromatin organization GO:0006325 206 0.015
peptide secretion GO:0002790 114 0.015
organelle localization GO:0051640 179 0.014
fatty acid metabolic process GO:0006631 121 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
hepaticobiliary system development GO:0061008 67 0.014
regulation of transporter activity GO:0032409 57 0.014
negative regulation of stem cell differentiation GO:2000737 14 0.014
regulation of protein localization GO:0032880 231 0.014
regulation of neuronal synaptic plasticity GO:0048168 30 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
amide transport GO:0042886 138 0.014
positive regulation of protein modification process GO:0031401 299 0.014
protein localization to organelle GO:0033365 185 0.013
positive regulation of blood pressure GO:0045777 21 0.013
metanephric nephron tubule development GO:0072234 16 0.013
regulation of inflammatory response GO:0050727 147 0.013
forebrain development GO:0030900 302 0.013
organophosphate catabolic process GO:0046434 232 0.013
asymmetric stem cell division GO:0098722 3 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
morphogenesis of embryonic epithelium GO:0016331 159 0.013
tube formation GO:0035148 140 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
response to extracellular stimulus GO:0009991 127 0.013
negative regulation of secretion GO:0051048 61 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
norepinephrine secretion GO:0048243 2 0.013
inner ear receptor cell development GO:0060119 39 0.013
regulation of systemic arterial blood pressure GO:0003073 61 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
negative regulation of protein modification process GO:0031400 163 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
alcohol metabolic process GO:0006066 116 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
gliogenesis GO:0042063 141 0.013
regulation of potassium ion transmembrane transport GO:1901379 11 0.013
small gtpase mediated signal transduction GO:0007264 97 0.012
aromatic compound catabolic process GO:0019439 286 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
mesonephric duct formation GO:0072181 2 0.012
bone remodeling GO:0046849 53 0.012
heterocycle catabolic process GO:0046700 280 0.012
metanephric distal convoluted tubule development GO:0072221 5 0.012
regulation of defense response GO:0031347 233 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
peptidyl serine modification GO:0018209 83 0.012
lipid transport GO:0006869 98 0.012
negative regulation of cell development GO:0010721 169 0.012
cellular lipid metabolic process GO:0044255 323 0.012
defense response to virus GO:0051607 68 0.012
modified amino acid transport GO:0072337 5 0.012
photoreceptor cell development GO:0042461 40 0.012
lipid localization GO:0010876 126 0.012
chromatin modification GO:0016568 187 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
body fluid secretion GO:0007589 53 0.012
purine nucleotide metabolic process GO:0006163 302 0.012
porphyrin containing compound biosynthetic process GO:0006779 16 0.011
response to inorganic substance GO:0010035 96 0.011
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
brain morphogenesis GO:0048854 32 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
nephron tubule morphogenesis GO:0072078 68 0.011
response to vitamin d GO:0033280 3 0.011
mammary gland morphogenesis GO:0060443 54 0.011
l glutamate uptake involved in synaptic transmission GO:0051935 3 0.011
methylation GO:0032259 134 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
activation of janus kinase activity GO:0042976 2 0.011
regulation of neurotransmitter levels GO:0001505 87 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
cell matrix adhesion GO:0007160 68 0.011
germ line stem cell division GO:0042078 2 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
forebrain neuron development GO:0021884 30 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
nucleotide metabolic process GO:0009117 332 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
somatic stem cell maintenance GO:0035019 47 0.010
negative regulation of pancreatic juice secretion GO:0090188 3 0.010
cellular potassium ion transport GO:0071804 43 0.010
development of primary sexual characteristics GO:0045137 143 0.010
forebrain generation of neurons GO:0021872 63 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
guanosine containing compound catabolic process GO:1901069 144 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
appendage morphogenesis GO:0035107 149 0.010
metanephric tubule development GO:0072170 18 0.010
protein import GO:0017038 101 0.010
gland development GO:0048732 330 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
regulation of hormone secretion GO:0046883 88 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
regulation of inward rectifier potassium channel activity GO:1901979 1 0.010

Slc5a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.154
cancer DOID:162 0 0.100
disease of metabolism DOID:0014667 0 0.093
organ system cancer DOID:0050686 0 0.051
acquired metabolic disease DOID:0060158 0 0.019
kidney disease DOID:557 0 0.017
disease of anatomical entity DOID:7 0 0.017
urinary system disease DOID:18 0 0.017
inherited metabolic disorder DOID:655 0 0.016
kidney cancer DOID:263 0 0.015
urinary system cancer DOID:3996 0 0.015
renal carcinoma DOID:4451 0 0.015
renal cell carcinoma DOID:4450 0 0.015
musculoskeletal system disease DOID:17 0 0.012
diabetes mellitus DOID:9351 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
type 1 diabetes mellitus DOID:9744 0 0.011
glucose metabolism disease DOID:4194 0 0.011