Mus musculus

0 known processes

Frs3

fibroblast growth factor receptor substrate 3

(Aliases: 4930417B13Rik,Snt2,MGC25496,AI449674,Frs2beta)

Frs3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 399 0.652
cation transmembrane transport GO:0098655 266 0.261
divalent metal ion transport GO:0070838 172 0.220
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.194
cellular ketone metabolic process GO:0042180 84 0.155
divalent inorganic cation transport GO:0072511 178 0.151
cellular amino acid metabolic process GO:0006520 103 0.124
transmembrane transport GO:0055085 412 0.123
regulation of cellular amine metabolic process GO:0033238 20 0.113
forebrain development GO:0030900 302 0.110
spermatogenesis GO:0007283 284 0.108
regulation of system process GO:0044057 200 0.107
regulation of ion transport GO:0043269 215 0.103
negative regulation of phosphorus metabolic process GO:0010563 184 0.100
axon guidance GO:0007411 141 0.098
metal ion homeostasis GO:0055065 189 0.095
regulation of neuron differentiation GO:0045664 281 0.085
negative regulation of protein metabolic process GO:0051248 282 0.080
nucleoside phosphate metabolic process GO:0006753 338 0.080
calcium ion transmembrane transport GO:0070588 85 0.076
amine metabolic process GO:0009308 45 0.075
phospholipid metabolic process GO:0006644 87 0.074
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.073
Human Mouse
negative regulation of molecular function GO:0044092 258 0.070
inorganic cation transmembrane transport GO:0098662 207 0.070
regulation of metal ion transport GO:0010959 106 0.069
mesonephric duct formation GO:0072181 2 0.066
regulation of cellular amino acid metabolic process GO:0006521 5 0.065
protein localization to organelle GO:0033365 185 0.065
nitrogen compound transport GO:0071705 271 0.065
regulation of cellular component biogenesis GO:0044087 181 0.061
regulation of cell cycle GO:0051726 281 0.061
negative regulation of phosphate metabolic process GO:0045936 184 0.061
regulation of secretion by cell GO:1903530 249 0.058
aromatic compound catabolic process GO:0019439 286 0.057
regulation of cellular response to stress GO:0080135 159 0.057
ion transmembrane transport GO:0034220 361 0.054
calcium ion transport GO:0006816 159 0.054
cerebral cortex development GO:0021987 86 0.052
axonogenesis GO:0007409 274 0.052
dendrite development GO:0016358 115 0.051
gland development GO:0048732 330 0.051
purine nucleotide metabolic process GO:0006163 302 0.048
intracellular protein transport GO:0006886 204 0.048
protein targeting GO:0006605 143 0.048
sensory perception GO:0007600 245 0.047
divalent inorganic cation homeostasis GO:0072507 138 0.047
inorganic ion transmembrane transport GO:0098660 234 0.047
negative regulation of phosphorylation GO:0042326 166 0.047
negative regulation of cell proliferation GO:0008285 296 0.047
organonitrogen compound biosynthetic process GO:1901566 192 0.047
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.047
positive regulation of ion transport GO:0043270 65 0.047
ribonucleotide metabolic process GO:0009259 291 0.046
telencephalon development GO:0021537 186 0.045
multi multicellular organism process GO:0044706 109 0.044
regulation of membrane potential GO:0042391 192 0.044
positive regulation of protein phosphorylation GO:0001934 242 0.043
macromolecule catabolic process GO:0009057 281 0.042
regulation of kinase activity GO:0043549 249 0.041
regulation of transferase activity GO:0051338 263 0.041
cell adhesion GO:0007155 329 0.040
regulation of ion transmembrane transport GO:0034765 119 0.040
chemotaxis GO:0006935 247 0.040
ribonucleoside metabolic process GO:0009119 245 0.040
germ cell development GO:0007281 185 0.039
embryonic organ morphogenesis GO:0048562 276 0.039
male gamete generation GO:0048232 285 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
retina development in camera type eye GO:0060041 119 0.038
regulation of cell projection organization GO:0031344 206 0.037
menarche GO:0042696 1 0.037
establishment of protein localization to organelle GO:0072594 118 0.037
mitotic cell cycle GO:0000278 195 0.037
cellular amine metabolic process GO:0044106 44 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
transmission of nerve impulse GO:0019226 76 0.036
neuron neuron synaptic transmission GO:0007270 69 0.036
regulation of protein kinase activity GO:0045859 232 0.036
organophosphate catabolic process GO:0046434 232 0.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.036
cellular homeostasis GO:0019725 240 0.036
regulation of hydrolase activity GO:0051336 246 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.035
cation homeostasis GO:0055080 212 0.035
positive regulation of protein modification process GO:0031401 299 0.035
muscle tissue development GO:0060537 308 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
cytoplasmic transport GO:0016482 234 0.034
sodium ion transport GO:0006814 73 0.034
mesoderm development GO:0007498 100 0.034
ras protein signal transduction GO:0007265 77 0.034
central nervous system neuron differentiation GO:0021953 162 0.034
digestive tract morphogenesis GO:0048546 147 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
cellular macromolecule catabolic process GO:0044265 206 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
small gtpase mediated signal transduction GO:0007264 97 0.033
oxidation reduction process GO:0055114 342 0.033
rna processing GO:0006396 105 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
cellular calcium ion homeostasis GO:0006874 119 0.032
organic anion transport GO:0015711 137 0.032
nucleoside metabolic process GO:0009116 246 0.032
circulatory system process GO:0003013 197 0.032
blood circulation GO:0008015 195 0.032
cellular protein catabolic process GO:0044257 155 0.031
positive regulation of cell cycle GO:0045787 92 0.031
regulation of nucleotide metabolic process GO:0006140 169 0.031
nucleotide metabolic process GO:0009117 332 0.031
regulation of mitotic cell cycle GO:0007346 126 0.031
digestive system development GO:0055123 200 0.031
peptidyl amino acid modification GO:0018193 336 0.031
hindbrain development GO:0030902 128 0.031
sensory system development GO:0048880 3 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
regulation of cytoskeleton organization GO:0051493 122 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.030
regulation of organelle organization GO:0033043 289 0.029
nuclear transport GO:0051169 139 0.029
regulation of secretion GO:0051046 274 0.029
organelle fission GO:0048285 170 0.029
regulation of lymphocyte activation GO:0051249 240 0.029
mitochondrion organization GO:0007005 134 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
response to organonitrogen compound GO:0010243 246 0.029
protein ubiquitination GO:0016567 171 0.028
cellular lipid metabolic process GO:0044255 323 0.028
positive regulation of nervous system development GO:0051962 221 0.028
gonad development GO:0008406 141 0.028
sensory organ morphogenesis GO:0090596 242 0.028
regulation of transporter activity GO:0032409 57 0.028
digestive tract development GO:0048565 190 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
positive regulation of ion transmembrane transport GO:0034767 24 0.027
respiratory system development GO:0060541 190 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
cellular chemical homeostasis GO:0055082 215 0.027
protein catabolic process GO:0030163 221 0.026
synapse organization GO:0050808 125 0.026
regulation of mapk cascade GO:0043408 248 0.026
regulation of calcium ion transport GO:0051924 69 0.026
lateral line system development GO:0048925 1 0.026
regulation of proteolysis GO:0030162 164 0.025
negative regulation of nervous system development GO:0051961 156 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
neuron projection guidance GO:0097485 141 0.025
regulation of transmembrane transport GO:0034762 128 0.025
positive regulation of cell development GO:0010720 237 0.025
positive regulation of hydrolase activity GO:0051345 148 0.025
negative regulation of intracellular signal transduction GO:1902532 167 0.025
neuron migration GO:0001764 122 0.025
sodium ion transmembrane transport GO:0035725 49 0.024
lateral inhibition GO:0046331 1 0.024
adult locomotory behavior GO:0008344 91 0.024
monoamine transport GO:0015844 33 0.024
regulation of retina development in camera type eye GO:1902866 3 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
anion transport GO:0006820 177 0.024
locomotory behavior GO:0007626 195 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.023
myotube differentiation GO:0014902 105 0.023
positive regulation of organelle organization GO:0010638 128 0.023
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.023
mapk cascade GO:0000165 281 0.023
Mouse
mrna metabolic process GO:0016071 84 0.023
multicellular organismal signaling GO:0035637 91 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
stem cell differentiation GO:0048863 268 0.022
cell division GO:0051301 120 0.022
gene silencing GO:0016458 38 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
dopamine uptake GO:0090494 4 0.022
negative regulation of protein modification process GO:0031400 163 0.022
regulation of cation channel activity GO:2001257 22 0.021
glycerolipid metabolic process GO:0046486 122 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
ossification GO:0001503 216 0.021
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
muscle cell differentiation GO:0042692 261 0.021
glucose homeostasis GO:0042593 128 0.021
microtubule based process GO:0007017 236 0.021
sulfur compound biosynthetic process GO:0044272 37 0.020
developmental growth involved in morphogenesis GO:0060560 138 0.020
positive regulation of cellular catabolic process GO:0031331 148 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
dna metabolic process GO:0006259 303 0.020
cell recognition GO:0008037 83 0.020
membrane organization GO:0061024 245 0.020
regulation of striated muscle cell differentiation GO:0051153 81 0.020
mrna processing GO:0006397 63 0.020
guanosine containing compound metabolic process GO:1901068 144 0.020
carbohydrate homeostasis GO:0033500 128 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.020
calcium ion homeostasis GO:0055074 127 0.019
gastrulation GO:0007369 116 0.019
skeletal system development GO:0001501 356 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
pallium development GO:0021543 120 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
glycerophospholipid metabolic process GO:0006650 71 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
notch signaling pathway GO:0007219 71 0.019
phenol containing compound metabolic process GO:0018958 60 0.019
adult behavior GO:0030534 135 0.018
purine containing compound metabolic process GO:0072521 311 0.018
cellular protein complex assembly GO:0043623 116 0.018
regulation of protein localization GO:0032880 231 0.018
organic acid transport GO:0015849 101 0.018
nuclear division GO:0000280 158 0.018
heart contraction GO:0060047 93 0.018
regulation of purine nucleotide catabolic process GO:0033121 122 0.018
smoothened signaling pathway GO:0007224 105 0.018
regulation of receptor activity GO:0010469 41 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
regulation of neural retina development GO:0061074 3 0.018
regulation of neuron projection development GO:0010975 169 0.018
negative regulation of kinase activity GO:0033673 81 0.018
regulation of cell adhesion GO:0030155 154 0.018
muscle system process GO:0003012 141 0.018
regulation of embryonic development GO:0045995 71 0.017
response to organic cyclic compound GO:0014070 198 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of cell migration GO:0030334 219 0.017
segmentation GO:0035282 93 0.017
apoptotic signaling pathway GO:0097190 306 0.017
fertilization GO:0009566 127 0.017
positive regulation of transferase activity GO:0051347 167 0.017
response to amino acid GO:0043200 37 0.017
peptidyl tyrosine modification GO:0018212 145 0.017
engulfment of apoptotic cell GO:0043652 3 0.017
cerebellum development GO:0021549 77 0.017
positive regulation of nucleotide metabolic process GO:0045981 114 0.017
maintenance of location GO:0051235 89 0.017
regulation of heart contraction GO:0008016 77 0.017
rna splicing GO:0008380 54 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
ribonucleotide catabolic process GO:0009261 208 0.016
regulation of neurotransmitter levels GO:0001505 87 0.016
compartment pattern specification GO:0007386 4 0.016
positive regulation of neuron differentiation GO:0045666 141 0.016
spermatid development GO:0007286 108 0.016
regulation of mitochondrion organization GO:0010821 27 0.016
sodium ion import GO:0097369 1 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
rna interference GO:0016246 2 0.016
establishment of organelle localization GO:0051656 122 0.016
positive regulation of nucleoside metabolic process GO:0045979 91 0.016
regulation of mrna metabolic process GO:1903311 43 0.016
compound eye development GO:0048749 1 0.016
carbohydrate metabolic process GO:0005975 230 0.015
central nervous system morphogenesis GO:0021551 2 0.015
positive regulation of kinase activity GO:0033674 155 0.015
epithelial cell proliferation GO:0050673 174 0.015
fat cell differentiation GO:0045444 160 0.015
nucleoside monophosphate metabolic process GO:0009123 85 0.015
cellular glucose homeostasis GO:0001678 52 0.015
regulation of intracellular transport GO:0032386 159 0.015
canonical wnt signaling pathway GO:0060070 130 0.015
ear morphogenesis GO:0042471 118 0.015
endomembrane system organization GO:0010256 147 0.015
development of primary male sexual characteristics GO:0046546 88 0.015
sequestering of metal ion GO:0051238 19 0.015
urogenital system development GO:0001655 261 0.015
mrna splicing via spliceosome GO:0000398 43 0.015
meiotic cell cycle GO:0051321 122 0.015
development of primary sexual characteristics GO:0045137 143 0.015
energy derivation by oxidation of organic compounds GO:0015980 77 0.015
neural tube development GO:0021915 160 0.015
stress activated mapk cascade GO:0051403 80 0.015
regulation of cytoplasmic transport GO:1903649 112 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
retina morphogenesis in camera type eye GO:0060042 45 0.014
regulation of reproductive process GO:2000241 66 0.014
single organism cell adhesion GO:0098602 156 0.014
anatomical structure homeostasis GO:0060249 145 0.014
bmp signaling pathway GO:0030509 93 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
neural crest cell development GO:0014032 48 0.014
stress activated protein kinase signaling cascade GO:0031098 81 0.014
positive regulation of apoptotic process GO:0043065 217 0.014
regulation of actin filament based process GO:0032970 99 0.014
regulation of synaptic plasticity GO:0048167 87 0.014
stem cell proliferation GO:0072089 117 0.014
regulation of nucleoside metabolic process GO:0009118 130 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.014
spermatid differentiation GO:0048515 115 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.014
cerebellar cortex development GO:0021695 48 0.014
camera type eye development GO:0043010 266 0.014
organic hydroxy compound biosynthetic process GO:1901617 77 0.014
sperm motility GO:0030317 47 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
gene silencing by rna GO:0031047 19 0.014
cellular response to dna damage stimulus GO:0006974 207 0.013
negative regulation of cell cycle GO:0045786 123 0.013
insulin secretion GO:0030073 89 0.013
positive regulation of intracellular transport GO:0032388 70 0.013
asymmetric stem cell division GO:0098722 3 0.013
regulation of cellular protein catabolic process GO:1903362 61 0.013
positive regulation of mitotic cell cycle GO:0045931 41 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
negative regulation of neuron differentiation GO:0045665 101 0.013
meiotic nuclear division GO:0007126 115 0.013
negative regulation of transferase activity GO:0051348 85 0.013
heart morphogenesis GO:0003007 178 0.013
purine containing compound catabolic process GO:0072523 213 0.013
positive regulation of vesicle fusion GO:0031340 2 0.013
septum transversum development GO:0003343 2 0.013
protein import into nucleus GO:0006606 95 0.013
epidermis development GO:0008544 187 0.013
peptidyl serine modification GO:0018209 83 0.013
ectoderm formation GO:0001705 3 0.013
positive regulation of cell projection organization GO:0031346 95 0.013
cellular response to oxidative stress GO:0034599 76 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
myeloid cell differentiation GO:0030099 233 0.013
positive regulation of transmembrane transport GO:0034764 29 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
positive regulation of megakaryocyte differentiation GO:0045654 4 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
regulation of stress activated mapk cascade GO:0032872 69 0.013
regulation of multi organism process GO:0043900 111 0.013
leukocyte migration GO:0050900 124 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
striated muscle tissue development GO:0014706 293 0.012
inner ear morphogenesis GO:0042472 101 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
regulation of peptide transport GO:0090087 91 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
ventricular cardiac muscle tissue development GO:0003229 38 0.012
cellular ion homeostasis GO:0006873 165 0.012
t cell activation GO:0042110 289 0.012
conditioned taste aversion GO:0001661 4 0.012
response to monosaccharide GO:0034284 67 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
regulation of auditory receptor cell differentiation GO:0045607 4 0.012
blastocyst development GO:0001824 80 0.012
neuron death GO:0070997 154 0.012
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
regulation of asymmetric cell division GO:0009786 4 0.012
organelle localization GO:0051640 179 0.012
hindbrain morphogenesis GO:0021575 46 0.012
positive regulation of protein transport GO:0051222 93 0.012
regulation of calcium ion transmembrane transporter activity GO:1901019 20 0.012
regulation of sodium ion transmembrane transport GO:1902305 9 0.012
regulation of nucleotide catabolic process GO:0030811 122 0.012
muscle fiber development GO:0048747 76 0.012
action potential GO:0001508 78 0.012
sensory perception of mechanical stimulus GO:0050954 107 0.011
mitotic nuclear division GO:0007067 48 0.011
glucan metabolic process GO:0044042 32 0.011
neurotransmitter secretion GO:0007269 62 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
negative regulation of cell development GO:0010721 169 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
steroid metabolic process GO:0008202 119 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
regulation of mitotic cell cycle phase transition GO:1901990 73 0.011
actin filament organization GO:0007015 113 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
regulation of homeostatic process GO:0032844 182 0.011
positive regulation of atpase activity GO:0032781 3 0.011
rna splicing via transesterification reactions GO:0000375 43 0.011
small molecule biosynthetic process GO:0044283 132 0.011
midbrain development GO:0030901 35 0.011
renal system development GO:0072001 225 0.011
neuromuscular process GO:0050905 99 0.011
regulation of ion homeostasis GO:2000021 64 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
catecholamine metabolic process GO:0006584 30 0.011
developmental cell growth GO:0048588 84 0.011
regulation of cell activation GO:0050865 289 0.011
type b pancreatic cell fate commitment GO:0003327 1 0.011
neuron apoptotic process GO:0051402 142 0.011
nucleotide catabolic process GO:0009166 217 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
synaptic transmission glutamatergic GO:0035249 36 0.011
respiratory gaseous exchange GO:0007585 43 0.011
negative regulation of mechanoreceptor differentiation GO:0045632 3 0.011
cell activation involved in immune response GO:0002263 126 0.011
organic hydroxy compound transport GO:0015850 93 0.011
mitotic cell cycle process GO:1903047 159 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
formation of organ boundary GO:0010160 1 0.011
oocyte axis specification GO:0007309 2 0.010
endocrine system development GO:0035270 98 0.010
cell proliferation in forebrain GO:0021846 30 0.010
diencephalon development GO:0021536 63 0.010
regulation of actin filament length GO:0030832 45 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
positive regulation of sodium ion transport GO:0010765 13 0.010
single organismal cell cell adhesion GO:0016337 131 0.010
cellular amide metabolic process GO:0043603 58 0.010
sequestering of calcium ion GO:0051208 18 0.010
epithelial cell development GO:0002064 159 0.010
amino acid transport GO:0006865 61 0.010
regulation of gamma aminobutyric acid secretion GO:0014052 2 0.010
negative regulation of gene silencing GO:0060969 2 0.010
cellular response to glucose stimulus GO:0071333 45 0.010
lipid biosynthetic process GO:0008610 179 0.010
dephosphorylation GO:0016311 129 0.010
memory GO:0007613 58 0.010
lymphocyte differentiation GO:0030098 242 0.010
response to glycoside GO:1903416 2 0.010
cellularization GO:0007349 1 0.010
cell differentiation involved in kidney development GO:0061005 33 0.010
epithelial cell migration GO:0010631 63 0.010
gliogenesis GO:0042063 141 0.010

Frs3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
central nervous system disease DOID:331 0 0.020
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.013