Mus musculus

0 known processes

Hjurp

Holliday junction recognition protein

(Aliases: Mfleg1,Gm975,C330011F01Rik,MGC66590)

Hjurp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.188
mitotic cell cycle process GO:1903047 159 0.110
cellular nitrogen compound catabolic process GO:0044270 280 0.109
macromolecule catabolic process GO:0009057 281 0.098
mitotic cell cycle GO:0000278 195 0.094
microtubule cytoskeleton organization GO:0000226 157 0.078
regulation of cell cycle GO:0051726 281 0.075
regulation of cell cycle process GO:0010564 160 0.068
organelle fission GO:0048285 170 0.067
microtubule based process GO:0007017 236 0.059
protein catabolic process GO:0030163 221 0.057
meiotic cell cycle GO:0051321 122 0.052
aromatic compound catabolic process GO:0019439 286 0.052
male gamete generation GO:0048232 285 0.052
organic cyclic compound catabolic process GO:1901361 295 0.051
cellular amine metabolic process GO:0044106 44 0.048
nuclear division GO:0000280 158 0.047
heterocycle catabolic process GO:0046700 280 0.046
cellular response to dna damage stimulus GO:0006974 207 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
amine metabolic process GO:0009308 45 0.043
regulation of organelle organization GO:0033043 289 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.040
negative regulation of protein metabolic process GO:0051248 282 0.039
cellularization GO:0007349 1 0.038
regulation of microtubule based process GO:0032886 52 0.038
regulation of cellular amine metabolic process GO:0033238 20 0.038
negative regulation of cellular component organization GO:0051129 194 0.037
ribonucleoside metabolic process GO:0009119 245 0.037
positive regulation of protein modification process GO:0031401 299 0.036
organonitrogen compound catabolic process GO:1901565 264 0.036
meiotic cell cycle process GO:1903046 77 0.035
lateral inhibition GO:0046331 1 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.034
ubiquitin dependent protein catabolic process GO:0006511 129 0.034
spermatogenesis GO:0007283 284 0.033
organophosphate catabolic process GO:0046434 232 0.033
meiotic nuclear division GO:0007126 115 0.033
regulation of mitotic cell cycle GO:0007346 126 0.032
maintenance of location GO:0051235 89 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
protein localization to organelle GO:0033365 185 0.032
chromosome segregation GO:0007059 48 0.032
nucleoside catabolic process GO:0009164 206 0.031
cellular ketone metabolic process GO:0042180 84 0.031
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
cellular amino acid metabolic process GO:0006520 103 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
regulation of transferase activity GO:0051338 263 0.030
protection from non homologous end joining at telomere GO:0031848 4 0.029
protein maturation GO:0051604 176 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
t cell activation GO:0042110 289 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
meiosis i GO:0007127 60 0.028
purine nucleoside metabolic process GO:0042278 241 0.028
nucleoside phosphate catabolic process GO:1901292 222 0.028
histone lysine methylation GO:0034968 50 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
proteasomal protein catabolic process GO:0010498 98 0.027
organelle assembly GO:0070925 177 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.026
germ cell development GO:0007281 185 0.026
regulation of protein localization GO:0032880 231 0.026
compound eye development GO:0048749 1 0.026
peptidyl amino acid modification GO:0018193 336 0.026
mitotic sister chromatid segregation GO:0000070 14 0.026
regulation of mitotic cell cycle phase transition GO:1901990 73 0.026
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
purine nucleotide catabolic process GO:0006195 211 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
cellular macromolecule catabolic process GO:0044265 206 0.025
cellular protein catabolic process GO:0044257 155 0.025
cellular protein complex assembly GO:0043623 116 0.025
leukocyte differentiation GO:0002521 342 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
mitotic nuclear division GO:0007067 48 0.025
nucleotide metabolic process GO:0009117 332 0.024
membrane organization GO:0061024 245 0.024
modification dependent protein catabolic process GO:0019941 133 0.024
regulation of apoptotic signaling pathway GO:2001233 197 0.024
purine containing compound catabolic process GO:0072523 213 0.023
microtubule organizing center organization GO:0031023 28 0.023
intracellular protein transport GO:0006886 204 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
nucleotide catabolic process GO:0009166 217 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
regulation of proteolysis GO:0030162 164 0.022
protein methylation GO:0006479 81 0.022
histone methylation GO:0016571 71 0.022
transmembrane transport GO:0055085 412 0.022
gonad development GO:0008406 141 0.022
anatomical structure homeostasis GO:0060249 145 0.022
purine containing compound metabolic process GO:0072521 311 0.021
microtubule polymerization or depolymerization GO:0031109 26 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
purine ribonucleoside metabolic process GO:0046128 241 0.021
organelle localization GO:0051640 179 0.021
cell division GO:0051301 120 0.021
cytoplasmic transport GO:0016482 234 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
regulation of lymphocyte activation GO:0051249 240 0.021
engulfment of apoptotic cell GO:0043652 3 0.020
regulation of kinase activity GO:0043549 249 0.020
signal transduction involved in dna damage checkpoint GO:0072422 3 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
chromosome organization involved in meiosis GO:0070192 39 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
regulation of cell activation GO:0050865 289 0.020
regulation of cell cycle phase transition GO:1901987 77 0.020
cytokine production GO:0001816 319 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
cellular response to hormone stimulus GO:0032870 150 0.020
modification dependent macromolecule catabolic process GO:0043632 133 0.020
mitochondrion organization GO:0007005 134 0.020
chromatin modification GO:0016568 187 0.020
negative regulation of cell cycle process GO:0010948 69 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
negative regulation of organelle organization GO:0010639 90 0.020
chromatin organization GO:0006325 206 0.019
nucleoside monophosphate metabolic process GO:0009123 85 0.019
neural tube development GO:0021915 160 0.019
dendrite development GO:0016358 115 0.019
immune effector process GO:0002252 321 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.019
negative regulation of mitotic cell cycle GO:0045930 58 0.019
synapsis GO:0007129 34 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
regulation of protein maturation GO:1903317 96 0.018
cation transport GO:0006812 399 0.018
lymphocyte differentiation GO:0030098 242 0.018
developmental maturation GO:0021700 193 0.018
response to organonitrogen compound GO:0010243 246 0.018
oxidation reduction process GO:0055114 342 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
apoptotic signaling pathway GO:0097190 306 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
protein import GO:0017038 101 0.018
sensory perception GO:0007600 245 0.018
myeloid cell differentiation GO:0030099 233 0.018
regulation of secretion by cell GO:1903530 249 0.018
regulation of intracellular transport GO:0032386 159 0.018
regulation of multi organism process GO:0043900 111 0.018
dna repair GO:0006281 107 0.018
b cell activation GO:0042113 161 0.018
regulation of cytoskeleton organization GO:0051493 122 0.018
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
macromolecule methylation GO:0043414 120 0.017
signal transduction involved in dna integrity checkpoint GO:0072401 3 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
negative regulation of cell cycle GO:0045786 123 0.017
ion transmembrane transport GO:0034220 361 0.017
regulation of cytokine production GO:0001817 266 0.017
protein ubiquitination GO:0016567 171 0.017
ribonucleoside catabolic process GO:0042454 206 0.017
development of primary sexual characteristics GO:0045137 143 0.016
protein processing GO:0016485 163 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
methylation GO:0032259 134 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.016
rho protein signal transduction GO:0007266 32 0.016
protein polymerization GO:0051258 57 0.016
glycosyl compound metabolic process GO:1901657 246 0.016
negative regulation of cell cycle phase transition GO:1901988 48 0.016
glycosyl compound catabolic process GO:1901658 206 0.016
small gtpase mediated signal transduction GO:0007264 97 0.016
cytokinetic process GO:0032506 2 0.016
intrinsic apoptotic signaling pathway GO:0097193 132 0.016
cellular lipid metabolic process GO:0044255 323 0.016
regulation of defense response GO:0031347 233 0.016
neural tube formation GO:0001841 108 0.016
establishment of organelle localization GO:0051656 122 0.016
homeostasis of number of cells GO:0048872 210 0.016
skeletal system development GO:0001501 356 0.016
telomere capping GO:0016233 4 0.016
nitrogen compound transport GO:0071705 271 0.016
regulation of protein kinase activity GO:0045859 232 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
purine ribonucleotide catabolic process GO:0009154 208 0.015
double strand break repair GO:0006302 48 0.015
innate immune response GO:0045087 157 0.015
camera type eye development GO:0043010 266 0.015
response to light stimulus GO:0009416 135 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
positive regulation of cell death GO:0010942 224 0.015
bone development GO:0060348 120 0.015
positive regulation of organelle organization GO:0010638 128 0.015
protein targeting GO:0006605 143 0.015
tube formation GO:0035148 140 0.015
positive regulation of proteolysis GO:0045862 85 0.015
ras protein signal transduction GO:0007265 77 0.014
endocytosis GO:0006897 168 0.014
divalent metal ion transport GO:0070838 172 0.014
protein localization to nucleus GO:0034504 121 0.014
cellular homeostasis GO:0019725 240 0.014
cellular response to lipid GO:0071396 145 0.014
regulation of hydrolase activity GO:0051336 246 0.014
mitotic cytokinesis GO:0000281 4 0.014
cell maturation GO:0048469 127 0.014
cell fate commitment GO:0045165 210 0.014
regulation of leukocyte proliferation GO:0070663 121 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of protein catabolic process GO:0042176 108 0.014
regulation of interleukin 1 alpha production GO:0032650 4 0.014
positive regulation of immune effector process GO:0002699 107 0.014
anion transport GO:0006820 177 0.014
regulation of secretion GO:0051046 274 0.013
blastocyst development GO:0001824 80 0.013
female gamete generation GO:0007292 74 0.013
inflammatory response GO:0006954 244 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
endomembrane system organization GO:0010256 147 0.013
regulation of homeostatic process GO:0032844 182 0.013
telomere maintenance in response to dna damage GO:0043247 4 0.013
covalent chromatin modification GO:0016569 163 0.013
response to radiation GO:0009314 165 0.013
histone modification GO:0016570 159 0.013
negative regulation of cell development GO:0010721 169 0.013
protein alkylation GO:0008213 81 0.013
lymphocyte proliferation GO:0046651 164 0.013
cellular response to insulin stimulus GO:0032869 78 0.013
cation transmembrane transport GO:0098655 266 0.013
epithelial tube formation GO:0072175 130 0.013
nucleoside metabolic process GO:0009116 246 0.013
regulation of membrane potential GO:0042391 192 0.013
positive regulation of cell cycle GO:0045787 92 0.013
male sex differentiation GO:0046661 109 0.013
regulation of defense response to bacterium GO:1900424 3 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
leukocyte proliferation GO:0070661 172 0.012
positive regulation of interleukin 1 alpha production GO:0032730 4 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of protein phosphorylation GO:0001934 242 0.012
dna conformation change GO:0071103 37 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
divalent inorganic cation transport GO:0072511 178 0.012
centrosome organization GO:0051297 26 0.012
regulation of asymmetric cell division GO:0009786 4 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.012
response to insulin GO:0032868 100 0.012
cilium morphogenesis GO:0060271 102 0.012
spermatid development GO:0007286 108 0.012
multicellular organismal signaling GO:0035637 91 0.012
regulation of cellular protein catabolic process GO:1903362 61 0.012
forebrain development GO:0030900 302 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
digestive system development GO:0055123 200 0.012
metaphase plate congression GO:0051310 2 0.012
response to lipopolysaccharide GO:0032496 128 0.012
connective tissue development GO:0061448 179 0.012
positive regulation of kinase activity GO:0033674 155 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
response to oxygen levels GO:0070482 62 0.012
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
production of molecular mediator of immune response GO:0002440 103 0.012
negative regulation of dna replication GO:0008156 4 0.012
positive regulation of cell cycle process GO:0090068 61 0.012
regulation of protein transport GO:0051223 163 0.012
dna recombination GO:0006310 92 0.012
regulation of cellular response to stress GO:0080135 159 0.012
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 3 0.012
negative regulation of cytoskeleton organization GO:0051494 36 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
nuclear transport GO:0051169 139 0.012
response to organic cyclic compound GO:0014070 198 0.011
angiogenesis GO:0001525 201 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
cellular response to peptide GO:1901653 92 0.011
double strand break repair via homologous recombination GO:0000724 21 0.011
multicellular organism growth GO:0035264 161 0.011
single organism nuclear import GO:1902593 95 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
negative regulation of nervous system development GO:0051961 156 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
spindle assembly involved in mitosis GO:0090307 4 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
regulation of cell division GO:0051302 76 0.011
negative regulation of molecular function GO:0044092 258 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
response to peptide GO:1901652 136 0.011
sensory perception of sound GO:0007605 97 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.011
cell type specific apoptotic process GO:0097285 268 0.011
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of immune system process GO:0002683 209 0.011
cilium assembly GO:0042384 81 0.011
regulation of b cell activation GO:0050864 81 0.011
circulatory system process GO:0003013 197 0.011
response to peptide hormone GO:0043434 127 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
blood vessel morphogenesis GO:0048514 285 0.011
antimicrobial peptide biosynthetic process GO:0002777 2 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
regulation of protein complex assembly GO:0043254 83 0.011
myosin filament organization GO:0031033 3 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.010
sensory organ morphogenesis GO:0090596 242 0.010
organic anion transport GO:0015711 137 0.010
regulation of t cell activation GO:0050863 170 0.010
leukocyte mediated immunity GO:0002443 174 0.010
synaptic transmission GO:0007268 329 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
astral microtubule organization GO:0030953 3 0.010
muscle tissue development GO:0060537 308 0.010
organism emergence from protective structure GO:0071684 4 0.010
skin development GO:0043588 220 0.010
rna interference GO:0016246 2 0.010
negative regulation of cell activation GO:0050866 111 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.010
atp catabolic process GO:0006200 55 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
respiratory system development GO:0060541 190 0.010
nuclear import GO:0051170 95 0.010
myeloid cell homeostasis GO:0002262 114 0.010
small molecule biosynthetic process GO:0044283 132 0.010
sperm individualization GO:0007291 1 0.010
positive regulation of protein catabolic process GO:0045732 60 0.010

Hjurp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.021
disease of anatomical entity DOID:7 0 0.021
disease of cellular proliferation DOID:14566 0 0.018
immune system disease DOID:2914 0 0.016
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
physical disorder DOID:0080015 0 0.011
central nervous system disease DOID:331 0 0.010
anemia DOID:2355 0 0.010
hematopoietic system disease DOID:74 0 0.010
thoracic cancer DOID:5093 0 0.010
breast cancer DOID:1612 0 0.010