Mus musculus

221 known processes

Npm1

nucleophosmin 1

(Aliases: NO38,MGC107291,MGC102162,Npm,B23)

Npm1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
translation GO:0006412 93 0.875
development of primary sexual characteristics GO:0045137 143 0.854
rna localization GO:0006403 23 0.811
oocyte anterior posterior axis specification GO:0007314 2 0.809
body morphogenesis GO:0010171 45 0.801
genitalia development GO:0048806 37 0.741
rna processing GO:0006396 105 0.719
germ cell development GO:0007281 185 0.621
translational initiation GO:0006413 24 0.617
oogenesis GO:0048477 56 0.588
positive regulation of peptidase activity GO:0010952 49 0.586
female gamete generation GO:0007292 74 0.586
regulation of cellular component biogenesis GO:0044087 181 0.450
rna splicing GO:0008380 54 0.437
regulation of mitotic cell cycle GO:0007346 126 0.424
dna repair GO:0006281 107 0.396
gonad development GO:0008406 141 0.372
positive regulation of cellular protein catabolic process GO:1903364 34 0.369
positive regulation of proteolysis GO:0045862 85 0.350
oocyte construction GO:0007308 2 0.337
cellular response to cytokine stimulus GO:0071345 189 0.296
regulation of proteolysis GO:0030162 164 0.287
ossification GO:0001503 216 0.283
segmentation GO:0035282 93 0.245
positive regulation of cellular catabolic process GO:0031331 148 0.238
regulation of peptidase activity GO:0052547 96 0.228
ribosomal small subunit biogenesis GO:0042274 4 0.226
mrna catabolic process GO:0006402 22 0.203
positive regulation of hydrolase activity GO:0051345 148 0.202
epithelial cell proliferation GO:0050673 174 0.199
regulation of rna splicing GO:0043484 37 0.197
organic cyclic compound catabolic process GO:1901361 295 0.189
positive regulation of apoptotic process GO:0043065 217 0.174
nuclear transport GO:0051169 139 0.171
positive regulation of endopeptidase activity GO:0010950 43 0.171
regulation of cell cycle GO:0051726 281 0.167
organelle fission GO:0048285 170 0.165
nucleic acid transport GO:0050657 18 0.159
cellular macromolecule catabolic process GO:0044265 206 0.158
regulation of protein localization GO:0032880 231 0.157
mitotic cell cycle process GO:1903047 159 0.150
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.149
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.144
meiotic cell cycle GO:0051321 122 0.138
regulation of cell activation GO:0050865 289 0.125
positive regulation of mrna metabolic process GO:1903313 17 0.125
regulation of embryonic development GO:0045995 71 0.123
pole plasm assembly GO:0007315 2 0.121
ncrna processing GO:0034470 26 0.121
cell growth GO:0016049 130 0.118
intracellular mrna localization GO:0008298 4 0.113
oocyte development GO:0048599 33 0.112
posttranscriptional regulation of gene expression GO:0010608 155 0.112
leukocyte differentiation GO:0002521 342 0.103
striated muscle tissue development GO:0014706 293 0.101
modification dependent macromolecule catabolic process GO:0043632 133 0.098
positive regulation of programmed cell death GO:0043068 218 0.097
hematopoietic progenitor cell differentiation GO:0002244 143 0.096
positive regulation of cell death GO:0010942 224 0.094
regulation of endopeptidase activity GO:0052548 89 0.094
regulation of cell cycle process GO:0010564 160 0.094
lung development GO:0030324 164 0.093
cellular nitrogen compound catabolic process GO:0044270 280 0.091
regulation of epithelial cell proliferation GO:0050678 141 0.091
stem cell differentiation GO:0048863 268 0.090
apoptotic signaling pathway GO:0097190 306 0.089
nucleocytoplasmic transport GO:0006913 139 0.086
single fertilization GO:0007338 82 0.085
rrna metabolic process GO:0016072 10 0.083
oocyte axis specification GO:0007309 2 0.081
regulation of muscle tissue development GO:1901861 97 0.081
mitotic nuclear division GO:0007067 48 0.077
stem cell development GO:0048864 219 0.076
regulation of cell division GO:0051302 76 0.076
regulation of mrna splicing via spliceosome GO:0048024 32 0.074
ribosome biogenesis GO:0042254 20 0.073
regulation of cellular catabolic process GO:0031329 242 0.072
mitotic cell cycle GO:0000278 195 0.068
cellular protein catabolic process GO:0044257 155 0.068
positive regulation of rna splicing GO:0033120 12 0.068
protein localization to nucleus GO:0034504 121 0.068
regulation of striated muscle cell differentiation GO:0051153 81 0.066
maternal determination of anterior posterior axis embryo GO:0008358 2 0.063
positive regulation of nucleotide metabolic process GO:0045981 114 0.062
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.061
regulation of translation GO:0006417 71 0.060
protein maturation GO:0051604 176 0.060
regulation of cellular response to stress GO:0080135 159 0.060
activation of cysteine type endopeptidase activity GO:0097202 27 0.059
fertilization GO:0009566 127 0.058
oocyte differentiation GO:0009994 35 0.058
cell division GO:0051301 120 0.053
microtubule cytoskeleton organization GO:0000226 157 0.053
negative regulation of cellular protein metabolic process GO:0032269 247 0.052
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.051
cell type specific apoptotic process GO:0097285 268 0.049
blood vessel morphogenesis GO:0048514 285 0.049
response to lipopolysaccharide GO:0032496 128 0.049
negative regulation of growth GO:0045926 99 0.048
nuclear transcribed mrna catabolic process GO:0000956 16 0.048
respiratory tube development GO:0030323 167 0.047
nuclear division GO:0000280 158 0.047
muscle tissue development GO:0060537 308 0.047
positive regulation of cell cycle phase transition GO:1901989 17 0.046
negative regulation of rna splicing GO:0033119 12 0.042
multicellular organismal aging GO:0010259 24 0.041
regulation of mrna processing GO:0050684 41 0.041
zymogen activation GO:0031638 41 0.040
ras protein signal transduction GO:0007265 77 0.040
mrna metabolic process GO:0016071 84 0.040
positive regulation of cellular component biogenesis GO:0044089 94 0.040
maturation of ssu rrna GO:0030490 1 0.039
regulation of cell cycle phase transition GO:1901987 77 0.039
digestive tract morphogenesis GO:0048546 147 0.037
determination of left right symmetry GO:0007368 80 0.037
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.036
3 utr mediated mrna stabilization GO:0070935 2 0.036
protein localization to organelle GO:0033365 185 0.036
regulation of lymphocyte differentiation GO:0045619 107 0.034
nuclear import GO:0051170 95 0.034
rna catabolic process GO:0006401 29 0.033
regulation of nucleocytoplasmic transport GO:0046822 73 0.033
rna splicing via transesterification reactions GO:0000375 43 0.033
microtubule organizing center organization GO:0031023 28 0.033
cellular response to dna damage stimulus GO:0006974 207 0.032
cell maturation GO:0048469 127 0.032
camera type eye development GO:0043010 266 0.031
regulation of leukocyte differentiation GO:1902105 159 0.031
regulation of organ morphogenesis GO:2000027 144 0.031
stem cell maintenance GO:0019827 130 0.031
regulation of nucleotide catabolic process GO:0030811 122 0.030
lymphocyte differentiation GO:0030098 242 0.030
ribonucleoprotein complex subunit organization GO:0071826 28 0.030
posttranscriptional gene silencing by rna GO:0035194 10 0.029
cellular response to lipid GO:0071396 145 0.029
regulation of hydrolase activity GO:0051336 246 0.029
spermatid differentiation GO:0048515 115 0.029
lymphocyte proliferation GO:0046651 164 0.029
heart morphogenesis GO:0003007 178 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.029
aromatic compound catabolic process GO:0019439 286 0.028
cartilage development GO:0051216 140 0.028
regulation of mitotic cell cycle phase transition GO:1901990 73 0.028
spermatid development GO:0007286 108 0.027
positive regulation of mitotic cell cycle GO:0045931 41 0.027
heterocycle catabolic process GO:0046700 280 0.026
small gtpase mediated signal transduction GO:0007264 97 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
digestive system development GO:0055123 200 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 8 0.025
inflammatory response GO:0006954 244 0.025
glycosyl compound catabolic process GO:1901658 206 0.024
regionalization GO:0003002 337 0.024
cytoplasmic transport GO:0016482 234 0.024
angiogenesis GO:0001525 201 0.024
positive regulation of mrna splicing via spliceosome GO:0048026 11 0.024
maintenance of location GO:0051235 89 0.024
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 8 0.024
regulation of cellular protein catabolic process GO:1903362 61 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
cell chemotaxis GO:0060326 81 0.023
negative regulation of cell growth GO:0030308 44 0.023
myotube differentiation GO:0014902 105 0.023
regulation of protein catabolic process GO:0042176 108 0.022
alternative mrna splicing via spliceosome GO:0000380 12 0.022
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.022
positive regulation of growth GO:0045927 104 0.021
regulation of cell growth GO:0001558 91 0.021
negative regulation of epithelial cell proliferation GO:0050680 64 0.021
chemotaxis GO:0006935 247 0.020
regulation of cysteine type endopeptidase activity GO:2000116 65 0.020
negative regulation of neuron death GO:1901215 98 0.020
cell cell recognition GO:0009988 44 0.020
establishment of organelle localization GO:0051656 122 0.020
epithelial tube morphogenesis GO:0060562 303 0.020
chromatin organization GO:0006325 206 0.020
Mouse
regulation of mrna stability GO:0043488 23 0.019
blastoderm segmentation GO:0007350 13 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
molting cycle GO:0042303 90 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
response to temperature stimulus GO:0009266 55 0.019
digestive tract development GO:0048565 190 0.019
regulation of oocyte development GO:0060281 9 0.019
placenta development GO:0001890 140 0.019
negative regulation of immune system process GO:0002683 209 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
regulation of reproductive process GO:2000241 66 0.019
skeletal system development GO:0001501 356 0.018
regulation of carbohydrate metabolic process GO:0006109 75 0.018
viral gene expression GO:0019080 3 0.018
dna packaging GO:0006323 30 0.018
cyclic nucleotide metabolic process GO:0009187 59 0.018
positive regulation of glycogen catabolic process GO:0045819 2 0.018
regulation of homeostatic process GO:0032844 182 0.017
polysaccharide metabolic process GO:0005976 39 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
response to oxygen levels GO:0070482 62 0.017
negative regulation of translation GO:0017148 22 0.017
ribosomal small subunit assembly GO:0000028 1 0.017
regulation of glycogen catabolic process GO:0005981 2 0.016
positive regulation of protein catabolic process GO:0045732 60 0.016
response to organic cyclic compound GO:0014070 198 0.016
embryonic axis specification GO:0000578 30 0.016
ion transmembrane transport GO:0034220 361 0.016
ribosomal large subunit biogenesis GO:0042273 5 0.016
dendrite development GO:0016358 115 0.016
positive regulation of epithelial cell proliferation GO:0050679 68 0.016
organophosphate catabolic process GO:0046434 232 0.016
t cell activation GO:0042110 289 0.016
wound healing GO:0042060 157 0.015
nucleotide metabolic process GO:0009117 332 0.015
meiotic nuclear division GO:0007126 115 0.015
neural tube formation GO:0001841 108 0.015
negative regulation of oxidative stress induced neuron death GO:1903204 2 0.015
single organism nuclear import GO:1902593 95 0.015
positive regulation of mrna processing GO:0050685 16 0.015
gene silencing GO:0016458 38 0.015
multicellular organism growth GO:0035264 161 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
regulation of binding GO:0051098 111 0.015
regulation of neuron death GO:1901214 134 0.015
skeletal muscle organ development GO:0060538 163 0.015
inorganic ion transmembrane transport GO:0098660 234 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
negative regulation of binding GO:0051100 39 0.015
mesenchymal cell differentiation GO:0048762 107 0.015
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
muscle cell differentiation GO:0042692 261 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
cellular ketone metabolic process GO:0042180 84 0.014
purine nucleotide biosynthetic process GO:0006164 65 0.014
trna processing GO:0008033 11 0.014
protein processing GO:0016485 163 0.014
regulation of translational initiation GO:0006446 15 0.014
response to heat GO:0009408 27 0.014
purine containing compound biosynthetic process GO:0072522 70 0.013
positive regulation of neuron differentiation GO:0045666 141 0.013
sperm individualization GO:0007291 1 0.013
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.013
myeloid cell differentiation GO:0030099 233 0.013
male gamete generation GO:0048232 285 0.013
male sex differentiation GO:0046661 109 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.013
regulation of cellular amine metabolic process GO:0033238 20 0.013
positive regulation of glucose metabolic process GO:0010907 21 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
neuron apoptotic process GO:0051402 142 0.012
organelle assembly GO:0070925 177 0.012
cation transmembrane transport GO:0098655 266 0.012
protein secretion GO:0009306 111 0.012
protein import GO:0017038 101 0.012
dna metabolic process GO:0006259 303 0.012
regulation of organelle organization GO:0033043 289 0.012
regulation of t cell costimulation GO:2000523 2 0.012
epidermis development GO:0008544 187 0.012
response to starvation GO:0042594 65 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
tube closure GO:0060606 91 0.011
respiratory system development GO:0060541 190 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
positive regulation of nucleotide catabolic process GO:0030813 88 0.011
negative regulation of mrna metabolic process GO:1903312 13 0.011
regulation of ras protein signal transduction GO:0046578 114 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
male gonad development GO:0008584 88 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.011
positive regulation of oxidative stress induced cell death GO:1903209 6 0.011
protein import into nucleus GO:0006606 95 0.011
development of primary male sexual characteristics GO:0046546 88 0.011
modification dependent protein catabolic process GO:0019941 133 0.011
carbohydrate metabolic process GO:0005975 230 0.011
leukocyte proliferation GO:0070661 172 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.010
rrna processing GO:0006364 10 0.010
determination of heart left right asymmetry GO:0061371 48 0.010
axon guidance GO:0007411 141 0.010
axonogenesis GO:0007409 274 0.010
lymphocyte activation involved in immune response GO:0002285 93 0.010
locomotory behavior GO:0007626 195 0.010
leukocyte migration GO:0050900 124 0.010
negative regulation of molecular function GO:0044092 258 0.010
blood circulation GO:0008015 195 0.010
endocytosis GO:0006897 168 0.010

Npm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.031
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
muscle tissue disease DOID:66 0 0.031
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
nervous system disease DOID:863 0 0.017
immune system cancer DOID:0060083 0 0.017
hematologic cancer DOID:2531 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
physical disorder DOID:0080015 0 0.015
motor neuron disease DOID:231 0 0.015
amyotrophic lateral sclerosis DOID:332 0 0.013