Mus musculus

10 known processes

Npm2

nucleophosmin/nucleoplasmin 2

(Aliases: MGC123507,MGC123506)

Npm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.058
apoptotic signaling pathway GO:0097190 306 0.046
transmembrane transport GO:0055085 412 0.045
cellular ketone metabolic process GO:0042180 84 0.039
regulation of cellular amine metabolic process GO:0033238 20 0.039
cellular amine metabolic process GO:0044106 44 0.038
cellular response to lipid GO:0071396 145 0.038
cation transport GO:0006812 399 0.036
regulation of cellular ketone metabolic process GO:0010565 66 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.035
regulation of neuron differentiation GO:0045664 281 0.034
cytokine production GO:0001816 319 0.032
regulation of cytokine production GO:0001817 266 0.032
nitrogen compound transport GO:0071705 271 0.032
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.031
sensory perception GO:0007600 245 0.031
g protein coupled receptor signaling pathway GO:0007186 243 0.031
ion transmembrane transport GO:0034220 361 0.030
macromolecule catabolic process GO:0009057 281 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
cellular response to organonitrogen compound GO:0071417 145 0.030
response to organonitrogen compound GO:0010243 246 0.029
response to acid chemical GO:0001101 111 0.029
neuronal action potential GO:0019228 54 0.029
amine metabolic process GO:0009308 45 0.029
multicellular organismal signaling GO:0035637 91 0.028
dna metabolic process GO:0006259 303 0.027
regulation of membrane potential GO:0042391 192 0.027
cation transmembrane transport GO:0098655 266 0.027
peptidyl amino acid modification GO:0018193 336 0.026
immune effector process GO:0002252 321 0.026
cell type specific apoptotic process GO:0097285 268 0.026
spermatogenesis GO:0007283 284 0.026
cell adhesion GO:0007155 329 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
response to organic cyclic compound GO:0014070 198 0.024
regulation of secretion by cell GO:1903530 249 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
oxidation reduction process GO:0055114 342 0.024
regulation of secretion GO:0051046 274 0.024
response to molecule of bacterial origin GO:0002237 143 0.024
positive regulation of protein modification process GO:0031401 299 0.023
Mouse
cellular homeostasis GO:0019725 240 0.023
Mouse
metal ion homeostasis GO:0055065 189 0.023
t cell activation GO:0042110 289 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
membrane organization GO:0061024 245 0.023
regulation of cell activation GO:0050865 289 0.023
action potential GO:0001508 78 0.023
protein ubiquitination GO:0016567 171 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
inflammatory response GO:0006954 244 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
Mouse
leukocyte differentiation GO:0002521 342 0.022
muscle system process GO:0003012 141 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
cation homeostasis GO:0055080 212 0.022
male gamete generation GO:0048232 285 0.022
protein catabolic process GO:0030163 221 0.022
response to lipopolysaccharide GO:0032496 128 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
defense response to other organism GO:0098542 197 0.021
homeostasis of number of cells GO:0048872 210 0.021
regulation of ion transport GO:0043269 215 0.021
regulation of protein localization GO:0032880 231 0.021
nucleotide metabolic process GO:0009117 332 0.021
synaptic transmission GO:0007268 329 0.021
negative regulation of immune system process GO:0002683 209 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
camera type eye development GO:0043010 266 0.021
transmission of nerve impulse GO:0019226 76 0.020
developmental maturation GO:0021700 193 0.020
cellular response to molecule of bacterial origin GO:0071219 83 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
sensory organ morphogenesis GO:0090596 242 0.020
anion transport GO:0006820 177 0.020
protein processing GO:0016485 163 0.020
cellular response to acid chemical GO:0071229 68 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
Mouse
muscle tissue development GO:0060537 308 0.020
endocytosis GO:0006897 168 0.020
cellular response to biotic stimulus GO:0071216 92 0.020
regulation of establishment of protein localization GO:0070201 181 0.019
positive regulation of nervous system development GO:0051962 221 0.019
cellular lipid metabolic process GO:0044255 323 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
skeletal system development GO:0001501 356 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
blood circulation GO:0008015 195 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
regulation of t cell activation GO:0050863 170 0.019
organic acid transport GO:0015849 101 0.019
cellular chemical homeostasis GO:0055082 215 0.018
muscle cell differentiation GO:0042692 261 0.018
regulation of organelle organization GO:0033043 289 0.018
Mouse
regulation of lymphocyte activation GO:0051249 240 0.018
negative regulation of protein metabolic process GO:0051248 282 0.018
maintenance of location GO:0051235 89 0.018
regulation of cell projection organization GO:0031344 206 0.018
chromatin organization GO:0006325 206 0.018
response to radiation GO:0009314 165 0.018
hematopoietic progenitor cell differentiation GO:0002244 143 0.018
germ cell development GO:0007281 185 0.018
organic anion transport GO:0015711 137 0.018
organic cyclic compound catabolic process GO:1901361 295 0.018
circulatory system process GO:0003013 197 0.018
protein maturation GO:0051604 176 0.018
ossification GO:0001503 216 0.018
regulation of transferase activity GO:0051338 263 0.017
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.017
response to amino acid GO:0043200 37 0.017
regulation of homeostatic process GO:0032844 182 0.017
regulation of reactive oxygen species metabolic process GO:2000377 40 0.017
purine ribonucleotide metabolic process GO:0009150 290 0.017
b cell activation GO:0042113 161 0.017
regulation of protein transport GO:0051223 163 0.017
positive regulation of cell development GO:0010720 237 0.017
regulation of intracellular transport GO:0032386 159 0.017
fertilization GO:0009566 127 0.017
lymphocyte differentiation GO:0030098 242 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
purine containing compound metabolic process GO:0072521 311 0.016
heterocycle catabolic process GO:0046700 280 0.016
regulation of hormone levels GO:0010817 211 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
forebrain development GO:0030900 302 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.016
divalent inorganic cation transport GO:0072511 178 0.016
myeloid cell differentiation GO:0030099 233 0.016
cellular divalent inorganic cation homeostasis GO:0072503 127 0.016
striated muscle tissue development GO:0014706 293 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of protein kinase activity GO:0045859 232 0.015
Mouse
sequestering of metal ion GO:0051238 19 0.015
regulation of defense response GO:0031347 233 0.015
skeletal muscle organ development GO:0060538 163 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
regulation of response to wounding GO:1903034 189 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
intracellular protein transport GO:0006886 204 0.015
regulation of system process GO:0044057 200 0.015
histone modification GO:0016570 159 0.015
positive regulation of cytokine production GO:0001819 174 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
microtubule based process GO:0007017 236 0.015
Mouse
cytoplasmic transport GO:0016482 234 0.015
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
divalent metal ion transport GO:0070838 172 0.015
positive regulation of secretion GO:0051047 130 0.015
endomembrane system organization GO:0010256 147 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
mitotic cell cycle GO:0000278 195 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.014
regulation of cell cycle GO:0051726 281 0.014
Mouse
muscle contraction GO:0006936 101 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
cellular response to dna damage stimulus GO:0006974 207 0.014
Mouse
covalent chromatin modification GO:0016569 163 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of kinase activity GO:0043549 249 0.014
Mouse
innate immune response GO:0045087 157 0.014
chromatin modification GO:0016568 187 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
ensheathment of neurons GO:0007272 76 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
anatomical structure homeostasis GO:0060249 145 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
carboxylic acid transport GO:0046942 100 0.014
ras protein signal transduction GO:0007265 77 0.014
positive regulation of secretion by cell GO:1903532 114 0.014
retina development in camera type eye GO:0060041 119 0.014
lipid transport GO:0006869 98 0.014
positive regulation of cell death GO:0010942 224 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
regulation of cell motility GO:2000145 236 0.014
leukocyte mediated immunity GO:0002443 174 0.014
adaptive immune response GO:0002250 155 0.014
regulation of feeding behavior GO:0060259 3 0.014
fat cell differentiation GO:0045444 160 0.014
multi multicellular organism process GO:0044706 109 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
negative regulation of nervous system development GO:0051961 156 0.014
skin development GO:0043588 220 0.014
peptide transport GO:0015833 133 0.014
cognition GO:0050890 149 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
response to peptide GO:1901652 136 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
spermatid differentiation GO:0048515 115 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
purine containing compound catabolic process GO:0072523 213 0.013
sulfur compound metabolic process GO:0006790 100 0.013
negative regulation of cell development GO:0010721 169 0.013
activation of immune response GO:0002253 138 0.013
cellular ion homeostasis GO:0006873 165 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
regulation of body fluid levels GO:0050878 162 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
respiratory tube development GO:0030323 167 0.013
negative regulation of cell cycle GO:0045786 123 0.013
negative regulation of protein modification process GO:0031400 163 0.013
axon ensheathment GO:0008366 76 0.013
response to inorganic substance GO:0010035 96 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
calcium ion homeostasis GO:0055074 127 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
positive regulation of immune effector process GO:0002699 107 0.013
neuron apoptotic process GO:0051402 142 0.013
methylation GO:0032259 134 0.013
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
mapk cascade GO:0000165 281 0.013
inorganic ion transmembrane transport GO:0098660 234 0.013
negative regulation of molecular function GO:0044092 258 0.013
protein secretion GO:0009306 111 0.013
respiratory system development GO:0060541 190 0.013
regulation of neuron projection development GO:0010975 169 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
blood vessel morphogenesis GO:0048514 285 0.013
detection of stimulus GO:0051606 84 0.012
small gtpase mediated signal transduction GO:0007264 97 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
regionalization GO:0003002 337 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
amide transport GO:0042886 138 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
axonogenesis GO:0007409 274 0.012
organelle fission GO:0048285 170 0.012
angiogenesis GO:0001525 201 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
positive regulation of defense response GO:0031349 124 0.012
regulation of hydrolase activity GO:0051336 246 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
lipid localization GO:0010876 126 0.012
positive regulation of apoptotic signaling pathway GO:2001235 95 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
aromatic compound catabolic process GO:0019439 286 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
regulation of mapk cascade GO:0043408 248 0.012
striated muscle cell development GO:0055002 125 0.012
gland development GO:0048732 330 0.012
calcium ion transport GO:0006816 159 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
single fertilization GO:0007338 82 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
regulation of proteolysis GO:0030162 164 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
regulation of blood pressure GO:0008217 93 0.012
kidney development GO:0001822 213 0.011
regulation of anatomical structure size GO:0090066 178 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
Mouse
nuclear division GO:0000280 158 0.011
carbohydrate homeostasis GO:0033500 128 0.011
actin cytoskeleton organization GO:0030036 220 0.011
response to light stimulus GO:0009416 135 0.011
renal system development GO:0072001 225 0.011
regulation of adaptive immune response GO:0002819 90 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of metal ion transport GO:0010959 106 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
spermatid development GO:0007286 108 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
neuron death GO:0070997 154 0.011
cell substrate adhesion GO:0031589 130 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
regulation of transmembrane transport GO:0034762 128 0.011
wound healing GO:0042060 157 0.011
gliogenesis GO:0042063 141 0.011
ear development GO:0043583 200 0.011
regulation of inflammatory response GO:0050727 147 0.011
negative regulation of apoptotic signaling pathway GO:2001234 104 0.011
leukocyte proliferation GO:0070661 172 0.011
carbohydrate metabolic process GO:0005975 230 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
positive regulation of organelle organization GO:0010638 128 0.011
Mouse
mrna metabolic process GO:0016071 84 0.011
Mouse
translation GO:0006412 93 0.011
extracellular structure organization GO:0043062 148 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
myelination GO:0042552 74 0.011
nucleoside metabolic process GO:0009116 246 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
multicellular organism growth GO:0035264 161 0.011
protein alkylation GO:0008213 81 0.011
mitotic cell cycle process GO:1903047 159 0.011
hormone secretion GO:0046879 128 0.011
regulation of cell cycle process GO:0010564 160 0.011
Mouse
cellular response to hormone stimulus GO:0032870 150 0.011
glial cell differentiation GO:0010001 131 0.011
organic hydroxy compound transport GO:0015850 93 0.011
cell maturation GO:0048469 127 0.011
protein localization to organelle GO:0033365 185 0.011
anion transmembrane transport GO:0098656 71 0.011
mitochondrion organization GO:0007005 134 0.011
skeletal system morphogenesis GO:0048705 203 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
protein methylation GO:0006479 81 0.011
muscle cell development GO:0055001 133 0.011
stem cell differentiation GO:0048863 268 0.011
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
leukocyte migration GO:0050900 124 0.011
single organism cell adhesion GO:0098602 156 0.010
response to growth factor GO:0070848 198 0.010
positive regulation of protein transport GO:0051222 93 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
tissue homeostasis GO:0001894 115 0.010
lymphocyte proliferation GO:0046651 164 0.010
locomotory behavior GO:0007626 195 0.010
positive regulation of cellular component biogenesis GO:0044089 94 0.010
lateral inhibition GO:0046331 1 0.010
urogenital system development GO:0001655 261 0.010
epithelial cell proliferation GO:0050673 174 0.010
amino acid transport GO:0006865 61 0.010
production of molecular mediator of immune response GO:0002440 103 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.010
detection of chemical stimulus involved in sensory perception of smell GO:0050911 4 0.010
regulation of ossification GO:0030278 112 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
Mouse
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.010
bone development GO:0060348 120 0.010
smoothened signaling pathway GO:0007224 105 0.010
organelle assembly GO:0070925 177 0.010
cell activation involved in immune response GO:0002263 126 0.010
chemotaxis GO:0006935 247 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
negative regulation of lymphocyte activation GO:0051250 91 0.010
response to oxidative stress GO:0006979 123 0.010
protein localization to membrane GO:0072657 108 0.010
glucose homeostasis GO:0042593 128 0.010

Npm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.031
central nervous system disease DOID:331 0 0.018
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.013
sensory system disease DOID:0050155 0 0.013
neurodegenerative disease DOID:1289 0 0.011