|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.330
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.269
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.231
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.230
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.221
|
Human |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.214
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.194
|
Human |
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.180
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.160
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.145
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.138
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.134
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.128
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.123
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.119
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.115
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.112
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.107
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.103
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.100
|
|
|
|
dna endoreduplication
|
GO:0042023 |
4 |
0.098
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.097
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.096
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.095
|
|
|
|
synapsis
|
GO:0007129 |
34 |
0.095
|
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.094
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.091
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.090
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.089
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.078
|
|
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.077
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.077
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.073
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.071
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.071
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.071
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.070
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.069
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.068
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.068
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.068
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.068
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.067
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.066
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.066
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.065
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.065
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.064
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.064
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.064
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.062
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.060
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.060
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.060
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.060
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.060
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.058
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.056
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.056
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.054
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.054
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.053
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.053
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.052
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.052
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.052
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.051
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.051
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.050
|
|
|
|
histone lysine demethylation
|
GO:0070076 |
13 |
0.049
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.049
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.049
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.049
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.049
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.049
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.048
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.048
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.047
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
57 |
0.046
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.046
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.044
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.044
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.043
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.043
|
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.043
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.043
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.043
|
|
|
|
chiasma assembly
|
GO:0051026 |
6 |
0.043
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.042
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.041
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.041
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.041
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.041
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.040
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.040
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.040
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.040
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.040
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.040
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.039
|
|
|
|
protein dealkylation
|
GO:0008214 |
13 |
0.039
|
|
|
|
rna processing
|
GO:0006396 |
105 |
0.039
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.039
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.038
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.038
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.038
|
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.038
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.038
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.037
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.037
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.037
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.037
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.037
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.036
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.035
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.035
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
1 |
0.035
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.035
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.035
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.034
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.034
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.034
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.034
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.034
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.034
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.034
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.033
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.033
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.033
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.033
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.032
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.032
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.032
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.032
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.032
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.032
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.032
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.032
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.031
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.031
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.031
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.031
|
|
|
|
demethylation
|
GO:0070988 |
23 |
0.031
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.030
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.030
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.030
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.030
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.030
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.030
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.030
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.030
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.029
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.029
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.029
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.029
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.029
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.029
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.029
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.028
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.028
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
25 |
0.028
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.028
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.028
|
|
|
|
chromosome organization involved in meiosis
|
GO:0070192 |
39 |
0.028
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.028
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.028
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.028
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.027
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.027
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.027
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.027
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.027
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.026
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.026
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
35 |
0.026
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.026
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.026
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.026
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.025
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.025
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.025
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.025
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.025
|
|
|
|
protein localization to chromatin
|
GO:0071168 |
3 |
0.025
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.025
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.025
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.024
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.024
|
|
|
|
negative regulation of translation
|
GO:0017148 |
22 |
0.024
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.024
|
|
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.024
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.024
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.024
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.024
|
|
|
|
centrosome separation
|
GO:0051299 |
4 |
0.024
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
71 |
0.024
|
|
|
|
positive regulation of potassium ion transport
|
GO:0043268 |
3 |
0.024
|
|
|
|
alcohol catabolic process
|
GO:0046164 |
16 |
0.024
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.024
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.023
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.023
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.023
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.023
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.023
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.022
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.022
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.022
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.022
|
|
|
|
dna methylation
|
GO:0006306 |
43 |
0.022
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
49 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.021
|
|
|
|
regulation of histone methylation
|
GO:0031060 |
30 |
0.021
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.021
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.021
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.021
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.021
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.021
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.021
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.021
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.021
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.021
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.021
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.021
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.021
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.021
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.021
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.020
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.020
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
35 |
0.020
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.020
|
|
|
|
tube formation
|
GO:0035148 |
140 |
0.020
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.020
|
|
|
|
response to retinoic acid
|
GO:0032526 |
56 |
0.020
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.019
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.019
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.019
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.019
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.019
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.019
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.019
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.019
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.019
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.018
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.018
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.018
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.018
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.018
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.018
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.018
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.018
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.018
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.018
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.018
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.018
|
|
|
|
rna splicing
|
GO:0008380 |
54 |
0.018
|
|
|
|
potassium ion transport
|
GO:0006813 |
52 |
0.018
|
|
|
|
histone h3 k9 dimethylation
|
GO:0036123 |
4 |
0.018
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.018
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
81 |
0.018
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.018
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.018
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.018
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.017
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.017
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.017
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.017
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.017
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.017
|
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.017
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.017
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.017
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
18 |
0.017
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.017
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.017
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.017
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
18 |
0.017
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.017
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.017
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.017
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.017
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.017
|
|
|
|
cellular biogenic amine metabolic process
|
GO:0006576 |
28 |
0.017
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.017
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.016
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.016
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.016
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.016
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.016
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.016
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.016
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.016
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.016
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.016
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.016
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.015
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.015
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
3 |
0.015
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.015
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.015
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.015
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.015
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.015
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
18 |
0.015
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.015
|
|
|
|
golgi to endosome transport
|
GO:0006895 |
3 |
0.015
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.015
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.015
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.015
|
|
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.015
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.015
|
|
|
|
cellular alcohol metabolic process
|
GO:0044107 |
3 |
0.015
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.015
|
|
|
|
translation
|
GO:0006412 |
93 |
0.015
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.015
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.015
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.015
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.015
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.015
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.015
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.015
|
|
|
|
protein demethylation
|
GO:0006482 |
13 |
0.015
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.014
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.014
|
|
|
|
mitochondrial genome maintenance
|
GO:0000002 |
15 |
0.014
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.014
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.014
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
105 |
0.014
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.014
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.014
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.014
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.014
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.014
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.014
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.014
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.014
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.014
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.014
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.014
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.014
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.014
|
|
|
|
synaptonemal complex organization
|
GO:0070193 |
15 |
0.014
|
|
|
|
negative regulation of histone h3 k9 methylation
|
GO:0051573 |
4 |
0.014
|
|
|
|
histone demethylation
|
GO:0016577 |
13 |
0.014
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.014
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.014
|
|
|
|
mitochondrial dna metabolic process
|
GO:0032042 |
13 |
0.014
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.014
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.014
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.013
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.013
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.013
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.013
|
|
|
|
phosphatidylethanolamine metabolic process
|
GO:0046337 |
2 |
0.013
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.013
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.013
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
44 |
0.013
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
1 |
0.013
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.013
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
1 |
0.013
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.013
|
|
|
|
response to hydroperoxide
|
GO:0033194 |
6 |
0.013
|
|
|
|
positive regulation of meiosis i
|
GO:0060903 |
5 |
0.013
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.013
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
28 |
0.013
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.013
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.013
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.013
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.013
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.013
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.013
|
|
|
|
rna 3 end processing
|
GO:0031123 |
20 |
0.013
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.013
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.013
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.013
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.013
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.013
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.013
|
|
|
|
organic hydroxy compound catabolic process
|
GO:1901616 |
25 |
0.013
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.013
|
|
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
2 |
0.013
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.013
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.012
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.012
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.012
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.012
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
62 |
0.012
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.012
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.012
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.012
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.012
|
|
|
|
regulation of pro b cell differentiation
|
GO:2000973 |
5 |
0.012
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.012
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.012
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.012
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.012
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.012
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.012
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
1 |
0.012
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.012
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.012
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.012
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.012
|
|
|
|
phosphatidylinositol phosphorylation
|
GO:0046854 |
23 |
0.012
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.012
|
Human |
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.012
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.012
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.012
|
|
|
|
axon target recognition
|
GO:0007412 |
4 |
0.012
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.011
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.011
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.011
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.011
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.011
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.011
|
|
|
|
glucocorticoid mediated signaling pathway
|
GO:0043402 |
3 |
0.011
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.011
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.011
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.011
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.011
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.011
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.011
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.011
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.011
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
18 |
0.011
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.011
|
|
|
|
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway
|
GO:0051482 |
4 |
0.011
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
20 |
0.011
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.011
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.011
|
|
|
|
harderian gland development
|
GO:0070384 |
2 |
0.011
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.011
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
3 |
0.011
|
|
|
|
phospholipase c activating serotonin receptor signaling pathway
|
GO:0007208 |
1 |
0.011
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.011
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.011
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
20 |
0.011
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.011
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.011
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.011
|
|
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.011
|
|
|
|
histone h3 k36 demethylation
|
GO:0070544 |
2 |
0.011
|
|
|
|
mitochondrion degradation
|
GO:0000422 |
3 |
0.011
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.011
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.011
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.011
|
|
|
|
lysosome organization
|
GO:0007040 |
21 |
0.010
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.010
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.010
|
|
|
|
thermosensory behavior
|
GO:0040040 |
1 |
0.010
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.010
|
|
|
|
protein deubiquitination
|
GO:0016579 |
19 |
0.010
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.010
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
3 |
0.010
|
|
|
|
regulation of cohesin localization to chromatin
|
GO:0071922 |
1 |
0.010
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
9 |
0.010
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.010
|
|
|
|
detection of bacterium
|
GO:0016045 |
7 |
0.010
|
|
|
|
regulation of protein sumoylation
|
GO:0033233 |
4 |
0.010
|
|
|
|
clathrin coat assembly
|
GO:0048268 |
2 |
0.010
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.010
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.010
|
|
|
|
pyruvate transport
|
GO:0006848 |
2 |
0.010
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.010
|
|
|
|
toxin transport
|
GO:1901998 |
38 |
0.010
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.010
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
19 |
0.010
|
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.010
|
|
|
|
fertilization
|
GO:0009566 |
127 |
0.010
|
|
