Mus musculus

141 known processes

Aars

alanyl-tRNA synthetase

(Aliases: MGC37368,C76919,AI316495,sti)

Aars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid activation GO:0043038 1 0.816
trna aminoacylation for protein translation GO:0006418 1 0.694
trna metabolic process GO:0006399 11 0.421
cellular amino acid metabolic process GO:0006520 103 0.352
translation GO:0006412 93 0.164
nucleobase containing small molecule metabolic process GO:0055086 352 0.116
ribonucleoside triphosphate catabolic process GO:0009203 199 0.090
cellular amine metabolic process GO:0044106 44 0.088
nucleoside triphosphate metabolic process GO:0009141 230 0.087
purine nucleoside triphosphate catabolic process GO:0009146 203 0.082
protein modification by small protein conjugation or removal GO:0070647 207 0.080
nucleotide metabolic process GO:0009117 332 0.078
cytoplasmic translational initiation GO:0002183 3 0.074
trna aminoacylation GO:0043039 1 0.073
regulation of cellular amine metabolic process GO:0033238 20 0.065
ribonucleotide catabolic process GO:0009261 208 0.062
gonad development GO:0008406 141 0.060
organonitrogen compound catabolic process GO:1901565 264 0.057
purine ribonucleoside metabolic process GO:0046128 241 0.057
purine containing compound catabolic process GO:0072523 213 0.056
regulation of cellular ketone metabolic process GO:0010565 66 0.056
purine containing compound metabolic process GO:0072521 311 0.056
modification dependent macromolecule catabolic process GO:0043632 133 0.055
ribose phosphate metabolic process GO:0019693 291 0.054
purine nucleoside metabolic process GO:0042278 241 0.054
cellular protein catabolic process GO:0044257 155 0.050
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.047
carbohydrate metabolic process GO:0005975 230 0.047
heterocycle catabolic process GO:0046700 280 0.047
positive regulation of cellular catabolic process GO:0031331 148 0.046
male gamete generation GO:0048232 285 0.046
ribonucleoside monophosphate catabolic process GO:0009158 57 0.044
amine metabolic process GO:0009308 45 0.044
carbohydrate derivative catabolic process GO:1901136 231 0.044
carbohydrate biosynthetic process GO:0016051 74 0.043
dna metabolic process GO:0006259 303 0.043
negative regulation of protein metabolic process GO:0051248 282 0.043
glycosyl compound catabolic process GO:1901658 206 0.043
protein modification by small protein conjugation GO:0032446 187 0.041
ribonucleoside metabolic process GO:0009119 245 0.040
cellular ketone metabolic process GO:0042180 84 0.040
glucose metabolic process GO:0006006 92 0.039
cristae formation GO:0042407 3 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
nucleoside catabolic process GO:0009164 206 0.036
response to endoplasmic reticulum stress GO:0034976 53 0.036
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.034
ribonucleoside catabolic process GO:0042454 206 0.034
regulation of cellular response to oxidative stress GO:1900407 19 0.034
monosaccharide metabolic process GO:0005996 106 0.034
macromolecule catabolic process GO:0009057 281 0.033
positive regulation of protein modification process GO:0031401 299 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
protein ubiquitination GO:0016567 171 0.032
spermatogenesis GO:0007283 284 0.032
hexose biosynthetic process GO:0019319 39 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
regulation of translation GO:0006417 71 0.032
aromatic compound catabolic process GO:0019439 286 0.031
neuron apoptotic process GO:0051402 142 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
rhythmic process GO:0048511 174 0.030
organophosphate catabolic process GO:0046434 232 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
regulation of ras protein signal transduction GO:0046578 114 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.029
multicellular organism growth GO:0035264 161 0.029
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.029
nucleoside phosphate catabolic process GO:1901292 222 0.029
purine nucleoside catabolic process GO:0006152 205 0.028
sensory organ morphogenesis GO:0090596 242 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
cytokine production GO:0001816 319 0.028
hexose metabolic process GO:0019318 98 0.028
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
spermatid differentiation GO:0048515 115 0.026
development of primary sexual characteristics GO:0045137 143 0.026
ion transmembrane transport GO:0034220 361 0.026
mitotic cell cycle GO:0000278 195 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
negative regulation of molecular function GO:0044092 258 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
lymphocyte differentiation GO:0030098 242 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
regulation of cell cycle GO:0051726 281 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
membrane organization GO:0061024 245 0.023
gland development GO:0048732 330 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
myeloid leukocyte differentiation GO:0002573 119 0.023
oligosaccharide catabolic process GO:0009313 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 5 0.022
stem cell differentiation GO:0048863 268 0.022
nucleoside metabolic process GO:0009116 246 0.022
response to extracellular stimulus GO:0009991 127 0.022
translational initiation GO:0006413 24 0.022
methionine transport GO:0015821 1 0.022
endocytosis GO:0006897 168 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
nucleoside triphosphate catabolic process GO:0009143 205 0.021
blastocyst development GO:0001824 80 0.021
metal ion homeostasis GO:0055065 189 0.021
nucleoside monophosphate metabolic process GO:0009123 85 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
cell type specific apoptotic process GO:0097285 268 0.020
protein catabolic process GO:0030163 221 0.020
maintenance of location GO:0051235 89 0.020
nucleoside monophosphate catabolic process GO:0009125 59 0.020
cellular response to external stimulus GO:0071496 88 0.020
modification dependent protein catabolic process GO:0019941 133 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
cellular lipid metabolic process GO:0044255 323 0.019
organonitrogen compound biosynthetic process GO:1901566 192 0.019
cellular macromolecule catabolic process GO:0044265 206 0.019
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.019
development of primary female sexual characteristics GO:0046545 73 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
atp catabolic process GO:0006200 55 0.019
nucleotide catabolic process GO:0009166 217 0.019
attachment of spindle microtubules to kinetochore GO:0008608 4 0.019
camera type eye development GO:0043010 266 0.019
ovarian follicle development GO:0001541 40 0.018
intrinsic apoptotic signaling pathway GO:0097193 132 0.018
protein targeting GO:0006605 143 0.018
regulation of cell activation GO:0050865 289 0.018
spermatid development GO:0007286 108 0.018
rna interference GO:0016246 2 0.018
divalent metal ion transport GO:0070838 172 0.018
connective tissue development GO:0061448 179 0.017
inclusion body assembly GO:0070841 3 0.017
folic acid containing compound metabolic process GO:0006760 3 0.017
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.017
negative regulation of neuron death GO:1901215 98 0.017
protein localization to organelle GO:0033365 185 0.017
transmembrane transport GO:0055085 412 0.017
regulation of wnt signaling pathway GO:0030111 123 0.017
branched chain amino acid transport GO:0015803 2 0.017
leukocyte differentiation GO:0002521 342 0.017
regulation of attachment of spindle microtubules to kinetochore GO:0051988 3 0.017
gluconeogenesis GO:0006094 39 0.017
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.016
regulation of transferase activity GO:0051338 263 0.016
neuron death GO:0070997 154 0.016
circadian regulation of gene expression GO:0032922 48 0.016
anion transmembrane transport GO:0098656 71 0.016
cation transmembrane transport GO:0098655 266 0.016
forebrain development GO:0030900 302 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of organelle organization GO:0033043 289 0.016
response to organic cyclic compound GO:0014070 198 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
cellular chemical homeostasis GO:0055082 215 0.016
female sex differentiation GO:0046660 84 0.016
monosaccharide biosynthetic process GO:0046364 44 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
cellular homeostasis GO:0019725 240 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.015
muscle cell differentiation GO:0042692 261 0.015
t cell activation GO:0042110 289 0.015
negative regulation of phosphorus metabolic process GO:0010563 184 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.015
carboxylic acid catabolic process GO:0046395 51 0.015
ras protein signal transduction GO:0007265 77 0.015
liver development GO:0001889 66 0.015
skeletal system development GO:0001501 356 0.015
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
response to acid chemical GO:0001101 111 0.014
pentose phosphate shunt GO:0006098 2 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
carbohydrate catabolic process GO:0016052 32 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
cation homeostasis GO:0055080 212 0.014
nuclear import GO:0051170 95 0.014
calcium ion homeostasis GO:0055074 127 0.014
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
organic acid transport GO:0015849 101 0.014
disaccharide metabolic process GO:0005984 1 0.013
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
defense response to other organism GO:0098542 197 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
positive regulation of cell death GO:0010942 224 0.013
cellular protein complex assembly GO:0043623 116 0.013
positive regulation of cell development GO:0010720 237 0.013
apoptotic signaling pathway GO:0097190 306 0.013
small molecule biosynthetic process GO:0044283 132 0.013
response to nutrient levels GO:0031667 109 0.013
lung development GO:0030324 164 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
organic cyclic compound catabolic process GO:1901361 295 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
sulfur amino acid transport GO:0000101 2 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
polyamine biosynthetic process GO:0006596 2 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
cellular amide metabolic process GO:0043603 58 0.012
response to organonitrogen compound GO:0010243 246 0.012
maturation of 5 8s rrna GO:0000460 1 0.012
stem cell development GO:0048864 219 0.012
fertilization GO:0009566 127 0.012
regulation of mapk cascade GO:0043408 248 0.011
ribonucleoside monophosphate metabolic process GO:0009161 80 0.011
protein maturation GO:0051604 176 0.011
regulation of protein catabolic process GO:0042176 108 0.011
chromatin organization GO:0006325 206 0.011
cellular calcium ion homeostasis GO:0006874 119 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of protein kinase activity GO:0045859 232 0.011
respiratory tube development GO:0030323 167 0.011
telencephalon development GO:0021537 186 0.011
phospholipid metabolic process GO:0006644 87 0.011
germ cell development GO:0007281 185 0.011
Worm
protein polymerization GO:0051258 57 0.011
renal system development GO:0072001 225 0.011
respiratory system development GO:0060541 190 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
anion transport GO:0006820 177 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
nadph regeneration GO:0006740 2 0.011
positive regulation of protein catabolic process GO:0045732 60 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
microtubule based process GO:0007017 236 0.011
macromolecular complex disassembly GO:0032984 43 0.011
amino acid transmembrane transport GO:0003333 37 0.011
nuclear transport GO:0051169 139 0.010
intracellular protein transport GO:0006886 204 0.010
cation transport GO:0006812 399 0.010
circadian rhythm GO:0007623 114 0.010
ossification GO:0001503 216 0.010
hepaticobiliary system development GO:0061008 67 0.010
nucleoside phosphate biosynthetic process GO:1901293 79 0.010
cellular response to lipid GO:0071396 145 0.010
transmission of nerve impulse GO:0019226 76 0.010
response to inorganic substance GO:0010035 96 0.010
gtp catabolic process GO:0006184 143 0.010
nucleotide biosynthetic process GO:0009165 78 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.010
regulation of cytokine production GO:0001817 266 0.010
positive regulation of protein kinase activity GO:0045860 144 0.010
wnt signaling pathway GO:0016055 188 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
response to peptide GO:1901652 136 0.010
cell adhesion GO:0007155 329 0.010
epithelial cell development GO:0002064 159 0.010
regulation of neuron projection development GO:0010975 169 0.010

Aars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.502
Human
nervous system disease DOID:863 0 0.502
Human
neuropathy DOID:870 0 0.502
Human
neuromuscular disease DOID:440 0 0.390
Human
charcot marie tooth disease type 2 DOID:0050539 0 0.385
Human
charcot marie tooth disease DOID:10595 0 0.385
Human
central nervous system disease DOID:331 0 0.077
neurodegenerative disease DOID:1289 0 0.033
sensory system disease DOID:0050155 0 0.016
retinal disease DOID:5679 0 0.013
retinal degeneration DOID:8466 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013