Mus musculus

12 known processes

Serpina3i

serine (or cysteine) peptidase inhibitor, clade A, member 3I

(Aliases: Gm6930,EG628900,2B2)

Serpina3i biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.080
regulation of cellular amino acid metabolic process GO:0006521 5 0.079
regulation of cellular amine metabolic process GO:0033238 20 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.054
Mouse
cellular amine metabolic process GO:0044106 44 0.053
amine metabolic process GO:0009308 45 0.049
cellular ketone metabolic process GO:0042180 84 0.048
Mouse
regulation of cytokine production GO:0001817 266 0.045
positive regulation of protein modification process GO:0031401 299 0.044
inflammatory response GO:0006954 244 0.044
cytokine production GO:0001816 319 0.040
negative regulation of protein metabolic process GO:0051248 282 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
immune effector process GO:0002252 321 0.038
regulation of cell activation GO:0050865 289 0.035
chemotaxis GO:0006935 247 0.035
regulation of defense response GO:0031347 233 0.032
t cell activation GO:0042110 289 0.031
organic cyclic compound catabolic process GO:1901361 295 0.031
cell adhesion GO:0007155 329 0.031
muscle cell differentiation GO:0042692 261 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
striated muscle tissue development GO:0014706 293 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
heterocycle catabolic process GO:0046700 280 0.029
peptidyl amino acid modification GO:0018193 336 0.028
nucleoside phosphate metabolic process GO:0006753 338 0.028
negative regulation of cell proliferation GO:0008285 296 0.027
leukocyte differentiation GO:0002521 342 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
muscle tissue development GO:0060537 308 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
regulation of kinase activity GO:0043549 249 0.024
aromatic compound catabolic process GO:0019439 286 0.024
nucleotide metabolic process GO:0009117 332 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
nucleoside catabolic process GO:0009164 206 0.022
response to lipopolysaccharide GO:0032496 128 0.022
cellular homeostasis GO:0019725 240 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.022
regulation of hydrolase activity GO:0051336 246 0.022
purine containing compound metabolic process GO:0072521 311 0.022
macromolecule catabolic process GO:0009057 281 0.021
organophosphate catabolic process GO:0046434 232 0.021
response to molecule of bacterial origin GO:0002237 143 0.021
cellular response to cytokine stimulus GO:0071345 189 0.021
regulation of transferase activity GO:0051338 263 0.021
mapk cascade GO:0000165 281 0.021
regulation of secretion GO:0051046 274 0.021
response to organonitrogen compound GO:0010243 246 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
Mouse
ras protein signal transduction GO:0007265 77 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
protein ubiquitination GO:0016567 171 0.020
nucleoside metabolic process GO:0009116 246 0.020
nucleotide catabolic process GO:0009166 217 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
blood vessel morphogenesis GO:0048514 285 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
sensory perception GO:0007600 245 0.020
protein secretion GO:0009306 111 0.020
regulation of establishment of protein localization GO:0070201 181 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
negative regulation of immune system process GO:0002683 209 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.019
regulation of response to wounding GO:1903034 189 0.019
regulation of neuron differentiation GO:0045664 281 0.019
regulation of protein kinase activity GO:0045859 232 0.019
protein processing GO:0016485 163 0.019
regulation of mapk cascade GO:0043408 248 0.019
cell type specific apoptotic process GO:0097285 268 0.019
glycosyl compound metabolic process GO:1901657 246 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
regulation of organelle organization GO:0033043 289 0.018
purine ribonucleotide metabolic process GO:0009150 290 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
protein maturation GO:0051604 176 0.018
regulation of secretion by cell GO:1903530 249 0.018
rho protein signal transduction GO:0007266 32 0.018
glycoprotein biosynthetic process GO:0009101 89 0.018
Mouse
regulation of inflammatory response GO:0050727 147 0.018
regulation of cholesterol metabolic process GO:0090181 14 0.017
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.017
purine nucleoside metabolic process GO:0042278 241 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
regulation of protein localization GO:0032880 231 0.017
purine nucleotide catabolic process GO:0006195 211 0.017
apoptotic signaling pathway GO:0097190 306 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.017
epithelial cell proliferation GO:0050673 174 0.017
ribonucleoside triphosphate metabolic process GO:0009199 220 0.017
blood circulation GO:0008015 195 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
ribose phosphate metabolic process GO:0019693 291 0.016
positive regulation of protein kinase activity GO:0045860 144 0.016
oxidation reduction process GO:0055114 342 0.016
divalent inorganic cation transport GO:0072511 178 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.016
angiogenesis GO:0001525 201 0.016
cation transport GO:0006812 399 0.016
cellular chemical homeostasis GO:0055082 215 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
positive regulation of transferase activity GO:0051347 167 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
nitrogen compound transport GO:0071705 271 0.016
negative regulation of molecular function GO:0044092 258 0.016
cellular lipid metabolic process GO:0044255 323 0.016
Mouse
renal system development GO:0072001 225 0.016
placenta development GO:0001890 140 0.016
regulation of membrane potential GO:0042391 192 0.016
regulation of cell migration GO:0030334 219 0.015
neutral lipid metabolic process GO:0006638 57 0.015
Mouse
small molecule biosynthetic process GO:0044283 132 0.015
regulation of anatomical structure size GO:0090066 178 0.015
axonogenesis GO:0007409 274 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
regulation of hormone levels GO:0010817 211 0.015
extracellular structure organization GO:0043062 148 0.015
purine nucleoside catabolic process GO:0006152 205 0.015
innate immune response GO:0045087 157 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
Mouse
glycoprotein metabolic process GO:0009100 116 0.015
Mouse
leukocyte proliferation GO:0070661 172 0.015
positive regulation of cytokine production GO:0001819 174 0.015
dna metabolic process GO:0006259 303 0.015
response to radiation GO:0009314 165 0.015
cellular macromolecule catabolic process GO:0044265 206 0.014
negative regulation of intracellular signal transduction GO:1902532 167 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
synaptic transmission GO:0007268 329 0.014
compound eye development GO:0048749 1 0.014
interspecies interaction between organisms GO:0044419 83 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
macromolecule glycosylation GO:0043413 55 0.014
Mouse
microtubule based process GO:0007017 236 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
lymphocyte proliferation GO:0046651 164 0.014
regulation of multi organism process GO:0043900 111 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
carbohydrate metabolic process GO:0005975 230 0.014
Mouse
cell growth GO:0016049 130 0.014
homeostasis of number of cells GO:0048872 210 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
calcium ion transport GO:0006816 159 0.013
myotube differentiation GO:0014902 105 0.013
response to growth factor GO:0070848 198 0.013
membrane organization GO:0061024 245 0.013
circulatory system process GO:0003013 197 0.013
cation homeostasis GO:0055080 212 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
b cell activation GO:0042113 161 0.013
calcium ion homeostasis GO:0055074 127 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
Mouse
activation of immune response GO:0002253 138 0.013
myeloid cell differentiation GO:0030099 233 0.013
male gamete generation GO:0048232 285 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
peptidyl tyrosine phosphorylation GO:0018108 143 0.013
ribonucleoside metabolic process GO:0009119 245 0.013
activation of nf kappab inducing kinase activity GO:0007250 4 0.013
glycosylation GO:0070085 62 0.013
Mouse
cation transmembrane transport GO:0098655 266 0.013
cell substrate adhesion GO:0031589 130 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
lymphocyte differentiation GO:0030098 242 0.012
negative regulation of protein modification process GO:0031400 163 0.012
regulation of protein processing GO:0070613 96 0.012
negative regulation of protein phosphorylation GO:0001933 126 0.012
fat cell differentiation GO:0045444 160 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
cellular response to peptide hormone stimulus GO:0071375 92 0.012
Mouse
negative regulation of phosphorylation GO:0042326 166 0.012
spermatogenesis GO:0007283 284 0.012
negative regulation of hydrolase activity GO:0051346 71 0.012
cellular metal ion homeostasis GO:0006875 151 0.012
cytoplasmic transport GO:0016482 234 0.012
striated muscle cell development GO:0055002 125 0.012
urogenital system development GO:0001655 261 0.012
carbohydrate homeostasis GO:0033500 128 0.012
cellular response to lipid GO:0071396 145 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
intracellular protein transport GO:0006886 204 0.012
protein localization to organelle GO:0033365 185 0.012
skeletal system development GO:0001501 356 0.012
positive regulation of programmed cell death GO:0043068 218 0.011
sequestering of calcium ion GO:0051208 18 0.011
skeletal muscle organ development GO:0060538 163 0.011
digestive tract development GO:0048565 190 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
cellular protein complex assembly GO:0043623 116 0.011
ossification GO:0001503 216 0.011
glycerolipid metabolic process GO:0046486 122 0.011
Mouse
epithelial cell development GO:0002064 159 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
regulation of protein transport GO:0051223 163 0.011
cardiac muscle tissue development GO:0048738 130 0.011
regulation of myotube differentiation GO:0010830 62 0.011
regulation of cell motility GO:2000145 236 0.011
extracellular matrix organization GO:0030198 147 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
immune response regulating signaling pathway GO:0002764 125 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
muscle contraction GO:0006936 101 0.011
t cell differentiation GO:0030217 174 0.011
regulation of cell projection organization GO:0031344 206 0.011
positive regulation of cell death GO:0010942 224 0.011
purine containing compound catabolic process GO:0072523 213 0.011
regulation of cell growth GO:0001558 91 0.011
regulation of cell adhesion GO:0030155 154 0.011
wound healing GO:0042060 157 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
purine ribonucleoside catabolic process GO:0046130 205 0.011
single organism cell adhesion GO:0098602 156 0.011
cell fate commitment GO:0045165 210 0.011
regulation of leukocyte differentiation GO:1902105 159 0.010
kidney epithelium development GO:0072073 121 0.010
regulation of proteolysis GO:0030162 164 0.010
negative regulation of proteolysis GO:0045861 74 0.010
positive regulation of nucleotide metabolic process GO:0045981 114 0.010
lateral inhibition GO:0046331 1 0.010
muscle cell development GO:0055001 133 0.010
leukocyte migration GO:0050900 124 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010
viral gene expression GO:0019080 3 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
regulation of cell cycle GO:0051726 281 0.010
defense response to virus GO:0051607 68 0.010
glucose homeostasis GO:0042593 128 0.010
organelle localization GO:0051640 179 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
organelle assembly GO:0070925 177 0.010
developmental maturation GO:0021700 193 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
regulation of muscle tissue development GO:1901861 97 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
lipid biosynthetic process GO:0008610 179 0.010
Mouse
divalent metal ion transport GO:0070838 172 0.010
monocarboxylic acid metabolic process GO:0032787 191 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010

Serpina3i disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.019
disease of anatomical entity DOID:7 0 0.019
disease of metabolism DOID:0014667 0 0.018
central nervous system disease DOID:331 0 0.013
organ system cancer DOID:0050686 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
inherited metabolic disorder DOID:655 0 0.013
immune system disease DOID:2914 0 0.013
musculoskeletal system disease DOID:17 0 0.011
neurodegenerative disease DOID:1289 0 0.010