Mus musculus

12 known processes

Serpina3m

serine (or cysteine) peptidase inhibitor, clade A, member 3M

(Aliases: spi2,Spi-2l,AI195004,3e46,Spi2.4,MMSPi2.4,Spi2-rs1,MMCM7,Spi-2rs1)

Serpina3m biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cholesterol metabolic process GO:0008203 56 0.534
Mouse
response to organonitrogen compound GO:0010243 246 0.393
small molecule biosynthetic process GO:0044283 132 0.352
cellular amino acid metabolic process GO:0006520 103 0.301
establishment of blood nerve barrier GO:0008065 3 0.290
regulation of secretion by cell GO:1903530 249 0.279
cellular lipid metabolic process GO:0044255 323 0.231
Mouse
negative regulation of endopeptidase activity GO:0010951 44 0.214
Mouse
negative regulation of hydrolase activity GO:0051346 71 0.197
Mouse
sterol metabolic process GO:0016125 58 0.193
Mouse
fatty acid metabolic process GO:0006631 121 0.172
regulation of cellular ketone metabolic process GO:0010565 66 0.163
Mouse
phosphatidylinositol mediated signaling GO:0048015 41 0.159
Mouse
alcohol metabolic process GO:0006066 116 0.146
Mouse
amine metabolic process GO:0009308 45 0.143
negative regulation of protein metabolic process GO:0051248 282 0.134
Mouse
coagulation GO:0050817 78 0.129
regulation of cellular amine metabolic process GO:0033238 20 0.126
regulation of secretion GO:0051046 274 0.126
negative regulation of cellular protein metabolic process GO:0032269 247 0.123
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.119
negative regulation of protein processing GO:0010955 79 0.115
Mouse
cellular ketone metabolic process GO:0042180 84 0.112
Mouse
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure GO:0001998 3 0.111
regulation of proteolysis GO:0030162 164 0.111
Mouse
angiogenesis GO:0001525 201 0.110
Rat
regulation of insulin receptor signaling pathway GO:0046626 21 0.110
Mouse
regulation of inflammatory response GO:0050727 147 0.108
monocarboxylic acid metabolic process GO:0032787 191 0.104
positive regulation of protein modification process GO:0031401 299 0.099
regulation of protein maturation GO:1903317 96 0.097
Mouse
negative regulation of proteolysis GO:0045861 74 0.096
Mouse
triglyceride metabolic process GO:0006641 51 0.094
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.093
activation of nf kappab inducing kinase activity GO:0007250 4 0.092
macromolecule glycosylation GO:0043413 55 0.091
Mouse
negative regulation of peptidase activity GO:0010466 46 0.090
Mouse
cation transport GO:0006812 399 0.087
renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure GO:0003072 5 0.086
cellular chemical homeostasis GO:0055082 215 0.083
blood vessel morphogenesis GO:0048514 285 0.083
Rat
regulation of defense response GO:0031347 233 0.083
inflammatory response GO:0006954 244 0.082
response to peptide hormone GO:0043434 127 0.082
lipid biosynthetic process GO:0008610 179 0.082
Mouse
protein maturation GO:0051604 176 0.079
Mouse
regulation of protein processing GO:0070613 96 0.079
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.078
Mouse
glycosylation GO:0070085 62 0.077
Mouse
drug metabolic process GO:0017144 4 0.075
positive regulation of activation of membrane attack complex GO:0001970 2 0.074
peptidyl amino acid modification GO:0018193 336 0.073
organic hydroxy compound metabolic process GO:1901615 203 0.072
Mouse
negative regulation of molecular function GO:0044092 258 0.071
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.071
regulation of cholesterol metabolic process GO:0090181 14 0.070
Mouse
neutral lipid metabolic process GO:0006638 57 0.070
Mouse
positive regulation of protein kinase c activity GO:1900020 1 0.069
positive regulation of transferase activity GO:0051347 167 0.069
wound healing GO:0042060 157 0.068
positive regulation of cellular amine metabolic process GO:0033240 5 0.068
cofactor metabolic process GO:0051186 80 0.068
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.065
Mouse
response to stilbenoid GO:0035634 22 0.064
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.063
Mouse
mesonephros development GO:0001823 97 0.063
glycoprotein biosynthetic process GO:0009101 89 0.062
Mouse
response to peptide GO:1901652 136 0.062
medium chain fatty acid metabolic process GO:0051791 1 0.062
steroid metabolic process GO:0008202 119 0.061
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.059
Mouse
regulation of peptidase activity GO:0052547 96 0.059
Mouse
acylglycerol metabolic process GO:0006639 55 0.059
Mouse
immune effector process GO:0002252 321 0.059
regulation of protein kinase c activity GO:1900019 1 0.059
cellular alcohol metabolic process GO:0044107 3 0.058
circulatory system process GO:0003013 197 0.057
organ regeneration GO:0031100 2 0.056
regulation of nucleotide metabolic process GO:0006140 169 0.056
regulation of cell activation GO:0050865 289 0.055
glycoprotein metabolic process GO:0009100 116 0.054
Mouse
regulation of endopeptidase activity GO:0052548 89 0.054
Mouse
glycerolipid metabolic process GO:0046486 122 0.053
Mouse
blood coagulation GO:0007596 76 0.052
protein processing GO:0016485 163 0.051
Mouse
positive regulation of programmed cell death GO:0043068 218 0.050
Rat
calcium ion homeostasis GO:0055074 127 0.050
epithelial tube morphogenesis GO:0060562 303 0.050
regulation of protein secretion GO:0050708 82 0.050
positive regulation of secretion by cell GO:1903532 114 0.049
carbohydrate biosynthetic process GO:0016051 74 0.049
Mouse
fat soluble vitamin biosynthetic process GO:0042362 4 0.049
regulation of protein kinase activity GO:0045859 232 0.049
cellular response to cytokine stimulus GO:0071345 189 0.049
macromolecule catabolic process GO:0009057 281 0.049
nitrogen compound transport GO:0071705 271 0.048
regulation of hormone levels GO:0010817 211 0.047
regulation of triglyceride metabolic process GO:0090207 17 0.046
Mouse
negative regulation of protein maturation GO:1903318 79 0.046
Mouse
cellular amine metabolic process GO:0044106 44 0.045
negative regulation of endothelial cell migration GO:0010596 4 0.045
kidney epithelium development GO:0072073 121 0.045
carbohydrate derivative biosynthetic process GO:1901137 183 0.045
Mouse
regulation of blood vessel size by renin angiotensin GO:0002034 5 0.044
cellular alcohol biosynthetic process GO:0044108 3 0.044
organonitrogen compound catabolic process GO:1901565 264 0.044
astrocyte activation GO:0048143 2 0.044
regulation of fatty acid biosynthetic process GO:0042304 12 0.043
carbohydrate metabolic process GO:0005975 230 0.043
Mouse
cellular response to insulin stimulus GO:0032869 78 0.043
Mouse
leukocyte mediated immunity GO:0002443 174 0.042
xenobiotic catabolic process GO:0042178 1 0.042
cell type specific apoptotic process GO:0097285 268 0.042
epithelial cell proliferation GO:0050673 174 0.041
Rat
fat cell differentiation GO:0045444 160 0.041
regulation of renal output by angiotensin GO:0002019 2 0.041
cellular response to cadmium ion GO:0071276 3 0.040
exogenous drug catabolic process GO:0042738 1 0.040
cytokine production GO:0001816 319 0.040
regulation of blood coagulation GO:0030193 28 0.040
lipid catabolic process GO:0016042 69 0.040
regulation of wound healing GO:0061041 40 0.039
positive regulation of mapk cascade GO:0043410 170 0.039
hemostasis GO:0007599 78 0.038
positive regulation of blood pressure GO:0045777 21 0.038
anion transport GO:0006820 177 0.038
positive regulation of apoptotic process GO:0043065 217 0.038
Rat
drug catabolic process GO:0042737 2 0.037
response to inorganic substance GO:0010035 96 0.037
cellular response to peptide GO:1901653 92 0.037
Mouse
regulation of hydrolase activity GO:0051336 246 0.036
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.036
morphogenesis of a branching structure GO:0001763 203 0.036
response to molecule of bacterial origin GO:0002237 143 0.035
response to organic cyclic compound GO:0014070 198 0.035
urogenital system development GO:0001655 261 0.035
cellular carbohydrate metabolic process GO:0044262 119 0.035
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.035
regulation of cell adhesion GO:0030155 154 0.035
regulation of carbohydrate biosynthetic process GO:0043255 40 0.035
Mouse
negative regulation of fibrinolysis GO:0051918 1 0.035
regulation of ossification GO:0030278 112 0.035
regulation of vesicle mediated transport GO:0060627 139 0.034
positive regulation of fatty acid biosynthetic process GO:0045723 3 0.034
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.034
regulation of kinase activity GO:0043549 249 0.034
regulation of response to wounding GO:1903034 189 0.034
response to insulin GO:0032868 100 0.034
Mouse
sequestering of calcium ion GO:0051208 18 0.034
regulation of protein transport GO:0051223 163 0.034
ureteric bud morphogenesis GO:0060675 62 0.034
regulation of mapk cascade GO:0043408 248 0.033
organelle localization GO:0051640 179 0.033
cation homeostasis GO:0055080 212 0.033
positive regulation of protein kinase activity GO:0045860 144 0.033
blood circulation GO:0008015 195 0.033
regulation of tube size GO:0035150 57 0.033
multicellular organism growth GO:0035264 161 0.033
inositol lipid mediated signaling GO:0048017 41 0.032
Mouse
monocarboxylic acid biosynthetic process GO:0072330 61 0.032
regulation of fibrinolysis GO:0051917 1 0.032
branching morphogenesis of an epithelial tube GO:0048754 159 0.032
regulation of ion transport GO:0043269 215 0.032
mesonephric tubule development GO:0072164 94 0.032
positive regulation of protein activation cascade GO:2000259 2 0.031
response to acid chemical GO:0001101 111 0.031
cellular response to hormone stimulus GO:0032870 150 0.031
Mouse
nucleotide metabolic process GO:0009117 332 0.031
cellular response to peptide hormone stimulus GO:0071375 92 0.031
Mouse
protein catabolic process GO:0030163 221 0.030
regulation of body fluid levels GO:0050878 162 0.030
mapk cascade GO:0000165 281 0.030
purine ribonucleoside catabolic process GO:0046130 205 0.030
cellular metal ion homeostasis GO:0006875 151 0.030
response to lipopolysaccharide GO:0032496 128 0.030
positive regulation of secretion GO:0051047 130 0.029
positive regulation of leukocyte mediated immunity GO:0002705 70 0.029
b cell mediated immunity GO:0019724 71 0.029
acute inflammatory response GO:0002526 41 0.029
regulation of leukocyte mediated immunity GO:0002703 104 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
regulation of cell growth GO:0001558 91 0.029
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.029
Mouse
camera type eye development GO:0043010 266 0.029
regulation of system process GO:0044057 200 0.028
maintenance of location GO:0051235 89 0.028
activation of adenylate cyclase activity GO:0007190 4 0.028
regulation of blood pressure GO:0008217 93 0.028
response to phenylpropanoid GO:0080184 22 0.028
cellular response to lipid GO:0071396 145 0.028
regulation of lipoprotein lipase activity GO:0051004 4 0.028
cellular nitrogen compound catabolic process GO:0044270 280 0.027
vitamin d3 metabolic process GO:0070640 3 0.027
fibrinolysis GO:0042730 3 0.027
defense response to bacterium GO:0042742 119 0.027
regulation of protein serine threonine kinase activity GO:0071900 157 0.027
positive regulation of lipid metabolic process GO:0045834 40 0.027
g protein coupled receptor signaling pathway GO:0007186 243 0.027
small gtpase mediated signal transduction GO:0007264 97 0.027
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.027
muscle cell differentiation GO:0042692 261 0.027
negative regulation of gluconeogenesis GO:0045721 9 0.027
Mouse
negative regulation of phospholipase activity GO:0010519 4 0.026
regulation of anatomical structure size GO:0090066 178 0.026
spermatogenesis GO:0007283 284 0.026
Mouse
innate immune response GO:0045087 157 0.026
hormone secretion GO:0046879 128 0.026
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.026
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
extracellular matrix organization GO:0030198 147 0.026
single organismal cell cell adhesion GO:0016337 131 0.025
exocytosis GO:0006887 121 0.025
regulation of establishment of protein localization GO:0070201 181 0.025
regulation of transferase activity GO:0051338 263 0.025
carboxylic acid biosynthetic process GO:0046394 86 0.025
kidney development GO:0001822 213 0.025
defense response to other organism GO:0098542 197 0.025
metal ion homeostasis GO:0055065 189 0.024
positive regulation of cell death GO:0010942 224 0.024
Rat
regulation of feeding behavior GO:0060259 3 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
regulation of carbohydrate metabolic process GO:0006109 75 0.024
Mouse
development of primary female sexual characteristics GO:0046545 73 0.024
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.023
response to temperature stimulus GO:0009266 55 0.023
ion transmembrane transport GO:0034220 361 0.023
chemotaxis GO:0006935 247 0.023
forebrain development GO:0030900 302 0.023
regulation of gluconeogenesis GO:0006111 30 0.023
Mouse
ovarian follicle rupture GO:0001543 2 0.023
humoral immune response GO:0006959 57 0.023
ameboidal type cell migration GO:0001667 128 0.023
peptide secretion GO:0002790 114 0.023
negative regulation of endothelial cell proliferation GO:0001937 8 0.023
Rat
nucleobase containing small molecule metabolic process GO:0055086 352 0.023
ras protein signal transduction GO:0007265 77 0.023
cellular divalent inorganic cation homeostasis GO:0072503 127 0.023
rho protein signal transduction GO:0007266 32 0.022
regulation of lipid biosynthetic process GO:0046890 54 0.022
Mouse
regulation of coagulation GO:0050818 31 0.022
oxidative demethylation GO:0070989 1 0.022
toxin catabolic process GO:0009407 1 0.022
organic hydroxy compound biosynthetic process GO:1901617 77 0.022
cellular homeostasis GO:0019725 240 0.022
renal system development GO:0072001 225 0.022
lymphocyte mediated immunity GO:0002449 139 0.022
negative regulation of protein modification process GO:0031400 163 0.021
heterocycle catabolic process GO:0046700 280 0.021
oxidation reduction process GO:0055114 342 0.021
single organism cell adhesion GO:0098602 156 0.021
positive regulation of kinase activity GO:0033674 155 0.021
mesonephric epithelium development GO:0072163 94 0.021
regulation of protein localization GO:0032880 231 0.021
response to drug GO:0042493 75 0.021
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.021
transmembrane transport GO:0055085 412 0.021
regulation of immunoglobulin mediated immune response GO:0002889 37 0.021
positive regulation of lipid biosynthetic process GO:0046889 18 0.021
rhythmic process GO:0048511 174 0.020
protein n linked glycosylation GO:0006487 12 0.020
Mouse
regulation of cell migration GO:0030334 219 0.020
positive regulation of steroid hormone secretion GO:2000833 2 0.020
hexose metabolic process GO:0019318 98 0.020
Mouse
response to extracellular stimulus GO:0009991 127 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
protein activation cascade GO:0072376 19 0.020
positive regulation of nucleotide metabolic process GO:0045981 114 0.020
negative regulation of immune system process GO:0002683 209 0.020
inflammatory response to wounding GO:0090594 4 0.020
reactive oxygen species metabolic process GO:0072593 84 0.020
cell substrate adhesion GO:0031589 130 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
positive regulation of cytokine production GO:0001819 174 0.020
sensory organ morphogenesis GO:0090596 242 0.020
cellular protein catabolic process GO:0044257 155 0.020
protein glycosylation GO:0006486 55 0.020
Mouse
regulation of purine nucleotide catabolic process GO:0033121 122 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
Rat
regulation of glucose metabolic process GO:0010906 60 0.019
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.019
porphyrin containing compound metabolic process GO:0006778 22 0.019
activation of membrane attack complex GO:0001905 4 0.019
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.019
developmental maturation GO:0021700 193 0.019
secondary alcohol metabolic process GO:1902652 3 0.019
nucleoside metabolic process GO:0009116 246 0.019
regulation of complement activation GO:0030449 7 0.019
regulation of membrane potential GO:0042391 192 0.019
regulation of angiogenesis GO:0045765 81 0.019
Rat
neuron migration GO:0001764 122 0.019
bone development GO:0060348 120 0.019
tissue remodeling GO:0048771 102 0.018
positive regulation of response to wounding GO:1903036 66 0.018
organic anion transport GO:0015711 137 0.018
leukocyte proliferation GO:0070661 172 0.018
myeloid leukocyte activation GO:0002274 83 0.018
positive regulation of angiogenesis GO:0045766 46 0.018
regulation of interleukin 8 production GO:0032677 3 0.018
heme metabolic process GO:0042168 16 0.018
extracellular structure organization GO:0043062 148 0.018
regulation of cytokine secretion GO:0050707 61 0.018
ribonucleotide metabolic process GO:0009259 291 0.018
regulation of blood vessel size GO:0050880 56 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.018
insulin receptor signaling pathway GO:0008286 49 0.018
Mouse
icosanoid metabolic process GO:0006690 33 0.018
sensory perception GO:0007600 245 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
aromatic compound catabolic process GO:0019439 286 0.018
positive regulation of nucleotide catabolic process GO:0030813 88 0.018
regulation of hormone secretion GO:0046883 88 0.017
renal system process GO:0003014 48 0.017
regulation of cytokine production GO:0001817 266 0.017
regulation of actin filament based process GO:0032970 99 0.017
positive regulation of nucleoside metabolic process GO:0045979 91 0.017
regulation of osteoblast differentiation GO:0045667 67 0.017
nucleoside catabolic process GO:0009164 206 0.017
regulation of organelle organization GO:0033043 289 0.017
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.017
cell adhesion GO:0007155 329 0.017
positive regulation of immune effector process GO:0002699 107 0.017
vitamin d biosynthetic process GO:0042368 3 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.017
phenol containing compound biosynthetic process GO:0046189 21 0.017
vascular process in circulatory system GO:0003018 62 0.017
endothelial cell proliferation GO:0001935 27 0.017
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.017
apoptotic signaling pathway GO:0097190 306 0.017
male gamete generation GO:0048232 285 0.017
Mouse
naphthalene metabolic process GO:0018931 1 0.017
regulation of peptide transport GO:0090087 91 0.017
nucleotide catabolic process GO:0009166 217 0.017
negative regulation of blood vessel morphogenesis GO:2000181 25 0.017
Rat
endothelial cell differentiation GO:0045446 41 0.016
response to oxidative stress GO:0006979 123 0.016
ureteric bud development GO:0001657 94 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
positive regulation of defense response GO:0031349 124 0.016
response to steroid hormone GO:0048545 56 0.016
negative regulation of ossification GO:0030279 49 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016
peptidyl serine phosphorylation GO:0018105 74 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
purine containing compound biosynthetic process GO:0072522 70 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
methylation GO:0032259 134 0.016
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
release of sequestered calcium ion into cytosol GO:0051209 42 0.016
positive regulation of growth GO:0045927 104 0.016
cellular calcium ion homeostasis GO:0006874 119 0.016
lipid localization GO:0010876 126 0.016
asymmetric stem cell division GO:0098722 3 0.016
regulation of peptidyl serine phosphorylation GO:0033135 39 0.016
regulation of adaptive immune response GO:0002819 90 0.016
tissue homeostasis GO:0001894 115 0.016
kidney morphogenesis GO:0060993 83 0.016
phasic smooth muscle contraction GO:0014821 8 0.016
i kappab kinase nf kappab signaling GO:0007249 85 0.016
negative regulation of cell activation GO:0050866 111 0.015
organ growth GO:0035265 117 0.015
amide transport GO:0042886 138 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
regulation of macrophage activation GO:0043030 17 0.015
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.015
cell recognition GO:0008037 83 0.015
regulation of postsynaptic membrane potential GO:0060078 48 0.015
dna metabolic process GO:0006259 303 0.015
nephron tubule development GO:0072080 84 0.015
vasoconstriction GO:0042310 27 0.015
fatty acid biosynthetic process GO:0006633 41 0.015
membrane depolarization GO:0051899 64 0.015
regulation of cell motility GO:2000145 236 0.015
myeloid cell activation involved in immune response GO:0002275 34 0.015
sequestering of metal ion GO:0051238 19 0.015
platelet activation GO:0030168 40 0.015
cell matrix adhesion GO:0007160 68 0.015
response to osmotic stress GO:0006970 21 0.015
regulation of action potential GO:0098900 4 0.015
negative regulation of coagulation GO:0050819 11 0.015
positive regulation of phospholipase activity GO:0010518 3 0.015
cell chemotaxis GO:0060326 81 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
endocrine process GO:0050886 39 0.014
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 6 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
nephron development GO:0072006 109 0.014
regulation of hemostasis GO:1900046 28 0.014
regulation of humoral immune response GO:0002920 22 0.014
regulation of vasculature development GO:1901342 88 0.014
Rat
immunoglobulin mediated immune response GO:0016064 69 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
tetrapyrrole metabolic process GO:0033013 22 0.014
negative regulation of lipoprotein lipase activity GO:0051005 1 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
homeostasis of number of cells GO:0048872 210 0.014
interleukin 8 secretion GO:0072606 3 0.014
anatomical structure homeostasis GO:0060249 145 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of organ morphogenesis GO:2000027 144 0.014
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.014
long chain fatty acid metabolic process GO:0001676 26 0.014
multi organism behavior GO:0051705 62 0.014
coenzyme metabolic process GO:0006732 52 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
secondary metabolite catabolic process GO:0090487 1 0.014
ossification GO:0001503 216 0.014
renin angiotensin regulation of aldosterone production GO:0002018 3 0.014
regulation of neuron differentiation GO:0045664 281 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
calcitriol biosynthetic process from calciol GO:0036378 3 0.014
interleukin 8 production GO:0032637 4 0.014
purine containing compound metabolic process GO:0072521 311 0.014
rna interference GO:0016246 2 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
response to purine containing compound GO:0014074 28 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
regulation of b cell mediated immunity GO:0002712 37 0.013
positive regulation of cell activation GO:0050867 158 0.013
telencephalon development GO:0021537 186 0.013
posttranscriptional regulation of gene expression GO:0010608 155 0.013
asymmetric neuroblast division GO:0055059 1 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of acute inflammatory response GO:0002673 27 0.013
glial cell development GO:0021782 54 0.013
glial cell differentiation GO:0010001 131 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
skeletal system morphogenesis GO:0048705 203 0.013
positive regulation of hormone secretion GO:0046887 38 0.013
response to hypoxia GO:0001666 58 0.013
bone remodeling GO:0046849 53 0.013
bone morphogenesis GO:0060349 78 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.013
regulation of lipase activity GO:0060191 15 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
cell cell recognition GO:0009988 44 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.013
positive regulation of systemic arterial blood pressure GO:0003084 9 0.013
positive regulation of cell migration GO:0030335 109 0.013
positive regulation of macrophage derived foam cell differentiation GO:0010744 4 0.013
organic acid transport GO:0015849 101 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
connective tissue replacement involved in inflammatory response wound healing GO:0002248 3 0.013
unsaturated fatty acid metabolic process GO:0033559 31 0.013
organic acid biosynthetic process GO:0016053 86 0.013
mesonephric tubule morphogenesis GO:0072171 63 0.013
cell division GO:0051301 120 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
acute inflammatory response to antigenic stimulus GO:0002438 12 0.012
protein secretion GO:0009306 111 0.012
regulation of lipid metabolic process GO:0019216 118 0.012
Mouse
multi multicellular organism process GO:0044706 109 0.012
organic acid catabolic process GO:0016054 51 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
branching involved in ureteric bud morphogenesis GO:0001658 56 0.012
monosaccharide biosynthetic process GO:0046364 44 0.012
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
peripheral nervous system development GO:0007422 53 0.012
cellular response to oxidative stress GO:0034599 76 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
gonad development GO:0008406 141 0.012
sensory perception of chemical stimulus GO:0007606 51 0.012
divalent inorganic cation transport GO:0072511 178 0.012
myeloid leukocyte mediated immunity GO:0002444 42 0.012
heart process GO:0003015 94 0.012
purine nucleoside triphosphate catabolic process GO:0009146 203 0.012
cytosolic calcium ion homeostasis GO:0051480 70 0.012
skeletal system development GO:0001501 356 0.012
nuclear division GO:0000280 158 0.012
hexose biosynthetic process GO:0019319 39 0.012
Mouse
nephron epithelium development GO:0072009 92 0.012
positive regulation of intracellular transport GO:0032388 70 0.012
connective tissue development GO:0061448 179 0.012
regulation of peptide secretion GO:0002791 77 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
Rat
regulation of neuron death GO:1901214 134 0.012
transition metal ion homeostasis GO:0055076 54 0.012

Serpina3m disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
immune system disease DOID:2914 0 0.022
disease of anatomical entity DOID:7 0 0.022
blood coagulation disease DOID:1247 0 0.022
inherited blood coagulation disease DOID:2214 0 0.022
hematopoietic system disease DOID:74 0 0.022
nervous system disease DOID:863 0 0.017
vascular disease DOID:178 0 0.017
cardiovascular system disease DOID:1287 0 0.017
artery disease DOID:0050828 0 0.015