Mus musculus

168 known processes

Eif2ak2

eukaryotic translation initiation factor 2-alpha kinase 2

(Aliases: Pkr,AI747578,4732414G15Rik,AI467567,Prkr,2310047A08Rik,Tik)

Eif2ak2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
viral process GO:0016032 41 0.777
defense response to virus GO:0051607 68 0.572
cellular response to dna damage stimulus GO:0006974 207 0.535
extrinsic apoptotic signaling pathway GO:0097191 126 0.532
negative regulation of multi organism process GO:0043901 68 0.458
immune effector process GO:0002252 321 0.425
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.409
cellular macromolecule catabolic process GO:0044265 206 0.379
activation of cysteine type endopeptidase activity GO:0097202 27 0.365
negative regulation of cell proliferation GO:0008285 296 0.358
Human
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.321
defense response to other organism GO:0098542 197 0.311
positive regulation of viral entry into host cell GO:0046598 3 0.308
viral life cycle GO:0019058 36 0.307
glycosyl compound metabolic process GO:1901657 246 0.306
regulation of defense response to virus by host GO:0050691 8 0.271
dna metabolic process GO:0006259 303 0.269
negative regulation of protein metabolic process GO:0051248 282 0.268
Human
natural killer cell proliferation GO:0001787 3 0.258
negative regulation of necroptotic process GO:0060546 9 0.253
positive regulation of peptidase activity GO:0010952 49 0.251
myeloid cell differentiation GO:0030099 233 0.250
interspecies interaction between organisms GO:0044419 83 0.243
negative regulation of molecular function GO:0044092 258 0.243
pattern recognition receptor signaling pathway GO:0002221 47 0.240
regulation of cell activation GO:0050865 289 0.232
leukocyte proliferation GO:0070661 172 0.225
negative regulation of immune system process GO:0002683 209 0.224
b cell activation GO:0042113 161 0.221
regulation of transferase activity GO:0051338 263 0.217
Human
activation of immune response GO:0002253 138 0.207
programmed necrotic cell death GO:0097300 28 0.203
immune response activating signal transduction GO:0002757 116 0.203
gland development GO:0048732 330 0.198
positive regulation of apoptotic signaling pathway GO:2001235 95 0.198
innate immune response GO:0045087 157 0.197
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.195
cellular response to cytokine stimulus GO:0071345 189 0.188
positive regulation of cell activation GO:0050867 158 0.185
cellular nitrogen compound catabolic process GO:0044270 280 0.180
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.176
apoptotic signaling pathway GO:0097190 306 0.174
protein oligomerization GO:0051259 67 0.174
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.170
regulation of necroptotic process GO:0060544 10 0.167
regulation of cell cycle GO:0051726 281 0.160
positive regulation of viral genome replication GO:0045070 2 0.159
myeloid cell homeostasis GO:0002262 114 0.158
regulation of peptidase activity GO:0052547 96 0.158
regulation of innate immune response GO:0045088 91 0.157
regulation of b cell activation GO:0050864 81 0.157
regulation of defense response to virus GO:0050688 18 0.154
cytokine production GO:0001816 319 0.148
positive regulation of proteolysis GO:0045862 85 0.146
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.144
cytoplasmic transport GO:0016482 234 0.139
regulation of cell migration GO:0030334 219 0.138
ribonucleoside monophosphate catabolic process GO:0009158 57 0.136
epithelial tube morphogenesis GO:0060562 303 0.135
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.134
regulation of cytokine production GO:0001817 266 0.129
b cell activation involved in immune response GO:0002312 50 0.128
regulation of endopeptidase activity GO:0052548 89 0.127
positive regulation of mapk cascade GO:0043410 170 0.126
regulation of cell motility GO:2000145 236 0.126
protein modification by small protein conjugation or removal GO:0070647 207 0.126
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.123
signal transduction in absence of ligand GO:0038034 55 0.122
lymphocyte activation involved in immune response GO:0002285 93 0.122
immune response regulating signaling pathway GO:0002764 125 0.122
protein modification by small protein conjugation GO:0032446 187 0.121
muscle cell differentiation GO:0042692 261 0.117
protein processing GO:0016485 163 0.117
regulation of cysteine type endopeptidase activity GO:2000116 65 0.116
regulation of leukocyte apoptotic process GO:2000106 56 0.114
protein catabolic process GO:0030163 221 0.114
nucleoside catabolic process GO:0009164 206 0.110
regulation of kinase activity GO:0043549 249 0.110
Human
regulation of proteolysis GO:0030162 164 0.108
i kappab kinase nf kappab signaling GO:0007249 85 0.107
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.107
regulation of leukocyte proliferation GO:0070663 121 0.107
positive regulation of endopeptidase activity GO:0010950 43 0.104
spleen development GO:0048536 39 0.102
rig i signaling pathway GO:0039529 4 0.100
positive regulation of cell death GO:0010942 224 0.099
response to organic cyclic compound GO:0014070 198 0.098
blood vessel morphogenesis GO:0048514 285 0.098
negative regulation of cellular component organization GO:0051129 194 0.095
epidermis development GO:0008544 187 0.094
positive regulation of protein modification process GO:0031401 299 0.094
Human
germ cell development GO:0007281 185 0.092
negative regulation of nervous system development GO:0051961 156 0.092
regulation of multi organism process GO:0043900 111 0.091
viral release from host cell GO:0019076 6 0.091
cell type specific apoptotic process GO:0097285 268 0.091
cell fate commitment GO:0045165 210 0.088
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.088
negative regulation of necrotic cell death GO:0060547 11 0.088
ribonucleoside triphosphate metabolic process GO:0009199 220 0.087
response to endoplasmic reticulum stress GO:0034976 53 0.086
ribonucleoside triphosphate catabolic process GO:0009203 199 0.086
posttranscriptional regulation of gene expression GO:0010608 155 0.086
Human
viral gene expression GO:0019080 3 0.086
leukocyte mediated immunity GO:0002443 174 0.086
innate immune response activating signal transduction GO:0002758 50 0.085
glial cell apoptotic process GO:0034349 3 0.085
lipid localization GO:0010876 126 0.085
glycosyl compound catabolic process GO:1901658 206 0.084
organic cyclic compound catabolic process GO:1901361 295 0.083
homeostasis of number of cells GO:0048872 210 0.083
necroptotic process GO:0070266 21 0.083
response to interferon gamma GO:0034341 34 0.080
cellular response to lipid GO:0071396 145 0.079
maintenance of location GO:0051235 89 0.079
atp metabolic process GO:0046034 75 0.079
regulation of membrane potential GO:0042391 192 0.079
nucleoside monophosphate metabolic process GO:0009123 85 0.079
aromatic compound catabolic process GO:0019439 286 0.078
atp catabolic process GO:0006200 55 0.078
carbohydrate derivative catabolic process GO:1901136 231 0.078
positive regulation of programmed cell death GO:0043068 218 0.077
negative regulation of protein modification process GO:0031400 163 0.077
regulation of t cell activation GO:0050863 170 0.076
cell activation involved in immune response GO:0002263 126 0.076
intracellular protein transport GO:0006886 204 0.076
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.076
skin development GO:0043588 220 0.075
necrotic cell death GO:0070265 30 0.074
regulation of viral release from host cell GO:1902186 6 0.074
purine nucleoside metabolic process GO:0042278 241 0.074
nucleoside phosphate metabolic process GO:0006753 338 0.071
positive regulation of kinase activity GO:0033674 155 0.071
Human
ribonucleoside catabolic process GO:0042454 206 0.071
urogenital system development GO:0001655 261 0.071
myeloid leukocyte differentiation GO:0002573 119 0.070
organelle assembly GO:0070925 177 0.070
leukocyte homeostasis GO:0001776 79 0.069
adaptive immune response GO:0002250 155 0.069
cellular lipid metabolic process GO:0044255 323 0.069
negative regulation of phosphate metabolic process GO:0045936 184 0.069
organophosphate catabolic process GO:0046434 232 0.068
regulation of reactive oxygen species metabolic process GO:2000377 40 0.068
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.068
regulation of lymphocyte activation GO:0051249 240 0.068
regulation of toll like receptor signaling pathway GO:0034121 20 0.067
protein maturation GO:0051604 176 0.067
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.067
angiogenesis GO:0001525 201 0.067
intrinsic apoptotic signaling pathway GO:0097193 132 0.066
positive regulation of interferon alpha production GO:0032727 4 0.066
cellular ketone metabolic process GO:0042180 84 0.065
cellular response to growth factor stimulus GO:0071363 197 0.065
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.065
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.064
double strand break repair GO:0006302 48 0.063
positive regulation of leukocyte proliferation GO:0070665 73 0.063
negative regulation of viral release from host cell GO:1902187 6 0.063
negative regulation of cellular protein metabolic process GO:0032269 247 0.063
Human
negative regulation of kinase activity GO:0033673 81 0.063
response to organonitrogen compound GO:0010243 246 0.063
heterocycle catabolic process GO:0046700 280 0.062
mammary gland epithelium development GO:0061180 65 0.062
endocytosis GO:0006897 168 0.062
regulation of response to biotic stimulus GO:0002831 38 0.061
lymphocyte homeostasis GO:0002260 64 0.061
nucleocytoplasmic transport GO:0006913 139 0.060
positive regulation of rig i signaling pathway GO:1900246 1 0.060
regulation of b cell proliferation GO:0030888 39 0.060
citrate metabolic process GO:0006101 3 0.060
regulation of apoptotic signaling pathway GO:2001233 197 0.058
macromolecule catabolic process GO:0009057 281 0.058
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.058
stem cell differentiation GO:0048863 268 0.058
negative regulation of transferase activity GO:0051348 85 0.058
purine ribonucleotide catabolic process GO:0009154 208 0.058
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.058
negative regulation of cytokine production GO:0001818 84 0.057
purine ribonucleotide metabolic process GO:0009150 290 0.057
response to oxidative stress GO:0006979 123 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.056
cellular response to lipopolysaccharide GO:0071222 77 0.056
regulation of cell adhesion GO:0030155 154 0.056
regulation of organelle organization GO:0033043 289 0.056
alpha beta t cell activation GO:0046631 91 0.056
b cell differentiation GO:0030183 78 0.055
regulation of viral entry into host cell GO:0046596 12 0.055
negative regulation of cell development GO:0010721 169 0.055
t cell proliferation GO:0042098 120 0.055
regulation of cellular catabolic process GO:0031329 242 0.055
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.055
ribose phosphate metabolic process GO:0019693 291 0.054
positive regulation of defense response GO:0031349 124 0.054
regulation of cellular component biogenesis GO:0044087 181 0.054
negative regulation of b cell activation GO:0050869 27 0.054
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.054
purine nucleoside triphosphate catabolic process GO:0009146 203 0.053
regulation of b cell differentiation GO:0045577 23 0.053
stem cell development GO:0048864 219 0.053
positive regulation of t cell activation GO:0050870 101 0.053
regulation of hydrolase activity GO:0051336 246 0.052
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.052
rna interference GO:0016246 2 0.052
entry into host cell GO:0030260 15 0.052
transmission of nerve impulse GO:0019226 76 0.052
regulation of leukocyte mediated immunity GO:0002703 104 0.052
regulation of homeostatic process GO:0032844 182 0.051
regulation of mapk cascade GO:0043408 248 0.051
mitotic cell cycle GO:0000278 195 0.051
b cell proliferation GO:0042100 53 0.051
male gamete generation GO:0048232 285 0.050
positive regulation of hydrolase activity GO:0051345 148 0.050
positive regulation of immune effector process GO:0002699 107 0.050
leukocyte apoptotic process GO:0071887 71 0.050
wound healing GO:0042060 157 0.050
purine nucleoside monophosphate metabolic process GO:0009126 81 0.049
purine containing compound catabolic process GO:0072523 213 0.049
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.049
regulation of response to wounding GO:1903034 189 0.049
regulation of protein kinase activity GO:0045859 232 0.049
Human
regulation of mast cell proliferation GO:0070666 4 0.049
apoptotic mitochondrial changes GO:0008637 48 0.049
t cell receptor signaling pathway GO:0050852 46 0.049
purine ribonucleoside metabolic process GO:0046128 241 0.049
inflammatory response GO:0006954 244 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.048
ribonucleoside monophosphate metabolic process GO:0009161 80 0.048
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.048
purine ribonucleoside catabolic process GO:0046130 205 0.048
mitochondrion organization GO:0007005 134 0.048
regulation of interferon beta production GO:0032648 13 0.048
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.047
regulation of protein serine threonine kinase activity GO:0071900 157 0.047
Human
regulation of lymphocyte proliferation GO:0050670 117 0.047
toll like receptor signaling pathway GO:0002224 38 0.047
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.047
entry into host GO:0044409 15 0.047
release of cytochrome c from mitochondria GO:0001836 23 0.046
cellular response to type i interferon GO:0071357 10 0.046
leukocyte differentiation GO:0002521 342 0.046
response to lipopolysaccharide GO:0032496 128 0.046
mast cell proliferation GO:0070662 4 0.046
kidney development GO:0001822 213 0.045
response to radiation GO:0009314 165 0.045
cellular response to oxidative stress GO:0034599 76 0.045
intracellular receptor signaling pathway GO:0030522 74 0.045
protein import GO:0017038 101 0.045
dna catabolic process endonucleolytic GO:0000737 15 0.045
protein polyubiquitination GO:0000209 33 0.045
regulation of interleukin 1 alpha production GO:0032650 4 0.045
epithelial cell proliferation GO:0050673 174 0.044
response to molecule of bacterial origin GO:0002237 143 0.044
positive regulation of apoptotic process GO:0043065 217 0.044
positive regulation of lymphocyte activation GO:0051251 140 0.044
protein localization to organelle GO:0033365 185 0.044
positive regulation of type i interferon production GO:0032481 14 0.044
ribonucleotide metabolic process GO:0009259 291 0.044
negative regulation of lymphocyte activation GO:0051250 91 0.043
negative regulation of viral transcription GO:0032897 3 0.043
cell adhesion GO:0007155 329 0.043
embryonic epithelial tube formation GO:0001838 130 0.043
nucleotide metabolic process GO:0009117 332 0.043
nucleoside triphosphate metabolic process GO:0009141 230 0.043
transmembrane transport GO:0055085 412 0.042
response to type i interferon GO:0034340 12 0.042
regulation of cellular response to stress GO:0080135 159 0.042
positive regulation of protein phosphorylation GO:0001934 242 0.042
Human
t helper 17 cell lineage commitment GO:0072540 4 0.042
positive regulation of cell adhesion GO:0045785 80 0.042
spermatid differentiation GO:0048515 115 0.042
ubiquitin dependent protein catabolic process GO:0006511 129 0.042
somatic cell dna recombination GO:0016444 51 0.042
zymogen activation GO:0031638 41 0.041
ion transmembrane transport GO:0034220 361 0.041
negative regulation of viral genome replication GO:0045071 10 0.041
mitotic cell cycle process GO:1903047 159 0.041
negative regulation of innate immune response GO:0045824 17 0.041
positive regulation of cytokine production GO:0001819 174 0.041
purine nucleoside triphosphate metabolic process GO:0009144 226 0.040
purine nucleoside catabolic process GO:0006152 205 0.040
positive regulation of cell cycle GO:0045787 92 0.040
chromatin modification GO:0016568 187 0.040
purine nucleotide catabolic process GO:0006195 211 0.040
interaction with host GO:0051701 22 0.039
positive regulation of transferase activity GO:0051347 167 0.039
Human
spermatogenesis GO:0007283 284 0.039
cytokine mediated signaling pathway GO:0019221 115 0.039
sensory organ morphogenesis GO:0090596 242 0.039
nucleotide catabolic process GO:0009166 217 0.039
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.039
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.039
Human
ribonucleoside metabolic process GO:0009119 245 0.039
rhythmic process GO:0048511 174 0.039
viral genome replication GO:0019079 17 0.039
morphogenesis of a branching structure GO:0001763 203 0.039
extracellular structure organization GO:0043062 148 0.038
leukocyte activation involved in immune response GO:0002366 126 0.038
negative regulation of protein phosphorylation GO:0001933 126 0.038
erythrocyte differentiation GO:0030218 88 0.038
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.038
tissue remodeling GO:0048771 102 0.038
organonitrogen compound catabolic process GO:1901565 264 0.037
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.037
peptidyl amino acid modification GO:0018193 336 0.037
nucleobase containing small molecule metabolic process GO:0055086 352 0.037
lymphocyte proliferation GO:0046651 164 0.037
regulation of neuron death GO:1901214 134 0.037
purine nucleoside monophosphate catabolic process GO:0009128 58 0.036
glial cell differentiation GO:0010001 131 0.036
cell substrate adhesion GO:0031589 130 0.036
lung development GO:0030324 164 0.036
regulation of rig i signaling pathway GO:0039535 2 0.036
neuronal action potential GO:0019228 54 0.036
modification dependent protein catabolic process GO:0019941 133 0.036
cellular response to interferon gamma GO:0071346 25 0.036
covalent chromatin modification GO:0016569 163 0.035
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
positive regulation of myeloid cell differentiation GO:0045639 43 0.035
negative regulation of t cell activation GO:0050868 65 0.035
regulation of myeloid cell differentiation GO:0045637 96 0.035
compound eye development GO:0048749 1 0.035
interleukin 6 production GO:0032635 58 0.034
negative regulation of b cell proliferation GO:0030889 13 0.034
forebrain development GO:0030900 302 0.034
protein import into nucleus GO:0006606 95 0.034
regulation of protein processing GO:0070613 96 0.034
type i interferon signaling pathway GO:0060337 10 0.034
regulation of mitotic cell cycle GO:0007346 126 0.034
spermatid development GO:0007286 108 0.034
cellular amine metabolic process GO:0044106 44 0.034
regulation of viral genome replication GO:0045069 13 0.033
morphogenesis of embryonic epithelium GO:0016331 159 0.033
multicellular organism growth GO:0035264 161 0.033
negative regulation of intracellular signal transduction GO:1902532 167 0.033
negative regulation of growth GO:0045926 99 0.033
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.033
establishment of protein localization to organelle GO:0072594 118 0.033
regulation of defense response GO:0031347 233 0.033
peptidyl tyrosine modification GO:0018212 145 0.033
positive regulation of innate immune response GO:0045089 80 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
response to uv GO:0009411 44 0.032
defense response to bacterium GO:0042742 119 0.032
positive regulation of interleukin 1 alpha production GO:0032730 4 0.032
nuclear transport GO:0051169 139 0.032
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.032
extracellular matrix organization GO:0030198 147 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
regulation of immunological synapse formation GO:2000520 2 0.032
reactive oxygen species metabolic process GO:0072593 84 0.031
multicellular organismal homeostasis GO:0048871 164 0.031
somatic diversification of immune receptors GO:0002200 53 0.031
cellular response to biotic stimulus GO:0071216 92 0.031
sensory perception of mechanical stimulus GO:0050954 107 0.031
cellular response to interferon alpha GO:0035457 4 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.031
antigen receptor mediated signaling pathway GO:0050851 64 0.031
anatomical structure homeostasis GO:0060249 145 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
neuron migration GO:0001764 122 0.030
macrophage differentiation GO:0030225 20 0.030
protein homooligomerization GO:0051260 43 0.030
monocarboxylic acid metabolic process GO:0032787 191 0.030
regulation of leukocyte differentiation GO:1902105 159 0.030
nucleoside metabolic process GO:0009116 246 0.030
glycosylation GO:0070085 62 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
lymphocyte differentiation GO:0030098 242 0.030
response to light stimulus GO:0009416 135 0.030
inorganic ion transmembrane transport GO:0098660 234 0.029
t cell activation GO:0042110 289 0.029
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.029
amine metabolic process GO:0009308 45 0.029
dna repair GO:0006281 107 0.029
muscle tissue development GO:0060537 308 0.029
protein localization to nucleus GO:0034504 121 0.029
mapk cascade GO:0000165 281 0.029
multicellular organismal signaling GO:0035637 91 0.029
negative regulation of phosphorylation GO:0042326 166 0.028
purine containing compound metabolic process GO:0072521 311 0.028
response to growth factor GO:0070848 198 0.028
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.028
axon ensheathment GO:0008366 76 0.028
ear development GO:0043583 200 0.028
proteasomal protein catabolic process GO:0010498 98 0.028
t cell apoptotic process GO:0070231 39 0.028
lipid storage GO:0019915 36 0.028
regulation of intracellular transport GO:0032386 159 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
positive regulation of organelle organization GO:0010638 128 0.028
cellular modified amino acid metabolic process GO:0006575 63 0.028
cellular response to extracellular stimulus GO:0031668 81 0.027
digestive system development GO:0055123 200 0.027
autophagy GO:0006914 45 0.027
actin cytoskeleton organization GO:0030036 220 0.027
cellular protein catabolic process GO:0044257 155 0.027
movement in host environment GO:0052126 15 0.027
negative regulation of cell migration GO:0030336 59 0.027
dna recombination GO:0006310 92 0.027
negative regulation of lymphocyte proliferation GO:0050672 45 0.027
regulation of type i interferon production GO:0032479 22 0.027
cell division GO:0051301 120 0.027
regulation of interleukin 6 production GO:0032675 55 0.026
response to ionizing radiation GO:0010212 42 0.026
mechanoreceptor differentiation GO:0042490 67 0.026
regulation of organ morphogenesis GO:2000027 144 0.026
negative regulation of homeostatic process GO:0032845 71 0.026
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.026
positive regulation of cell migration GO:0030335 109 0.026
negative regulation of apoptotic signaling pathway GO:2001234 104 0.026
negative regulation of defense response GO:0031348 77 0.026
muscle cell development GO:0055001 133 0.026
response to oxygen levels GO:0070482 62 0.026
response to interleukin 15 GO:0070672 3 0.026
anion transport GO:0006820 177 0.026
cellular component assembly involved in morphogenesis GO:0010927 139 0.026
regulation of ion transport GO:0043269 215 0.026
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.025
sensory perception of sound GO:0007605 97 0.025
negative regulation of interferon beta production GO:0032688 3 0.025
negative regulation of phosphorus metabolic process GO:0010563 184 0.025
cellularization GO:0007349 1 0.025
single organism nuclear import GO:1902593 95 0.025
activation of innate immune response GO:0002218 56 0.025
negative regulation of protein processing GO:0010955 79 0.025
t cell homeostasis GO:0043029 35 0.025
schwann cell differentiation GO:0014037 26 0.025
viral transcription GO:0019083 3 0.025
regulation of protein transport GO:0051223 163 0.025
action potential GO:0001508 78 0.025
tube formation GO:0035148 140 0.025
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.025
actin polymerization or depolymerization GO:0008154 54 0.025
positive regulation of glial cell proliferation GO:0060252 4 0.024
negative regulation of viral entry into host cell GO:0046597 10 0.024
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.024
chromatin organization GO:0006325 206 0.024
regulation of thymocyte apoptotic process GO:0070243 14 0.024
regulation of defense response to bacterium GO:1900424 3 0.024
positive regulation of b cell activation GO:0050871 49 0.024
isotype switching GO:0045190 36 0.024
telomere maintenance GO:0000723 19 0.024
positive regulation of b cell differentiation GO:0045579 13 0.024
production of small rna involved in gene silencing by rna GO:0070918 6 0.024
gliogenesis GO:0042063 141 0.024
modification dependent macromolecule catabolic process GO:0043632 133 0.024
epithelial cell development GO:0002064 159 0.024
membrane depolarization GO:0051899 64 0.024
pallium development GO:0021543 120 0.024
interleukin 1 alpha secretion GO:0050703 3 0.024
negative regulation of cell motility GO:2000146 61 0.024
morphogenesis of a branching epithelium GO:0061138 193 0.023
regulation of protein maturation GO:1903317 96 0.023
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.023
interferon beta production GO:0032608 16 0.023
cellular response to interferon beta GO:0035458 21 0.023
protein polymerization GO:0051258 57 0.023
regulation of interleukin 1 alpha secretion GO:0050705 3 0.023
cellular response to external stimulus GO:0071496 88 0.023
cellular response to peptide GO:1901653 92 0.023
production of molecular mediator of immune response GO:0002440 103 0.023
regulation of neuron apoptotic process GO:0043523 122 0.023
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.023
Human
negative regulation of cell activation GO:0050866 111 0.023
regulation of schwann cell proliferation GO:0010624 2 0.023
negative regulation of immune effector process GO:0002698 55 0.023
hatching GO:0035188 4 0.023
cellular protein complex assembly GO:0043623 116 0.022
membrane organization GO:0061024 245 0.022
neural tube formation GO:0001841 108 0.022
digestive tract development GO:0048565 190 0.022
sensory perception GO:0007600 245 0.022
regulation of protein catabolic process GO:0042176 108 0.022
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.022
interleukin 8 production GO:0032637 4 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
alpha amino acid metabolic process GO:1901605 59 0.022
cartilage development GO:0051216 140 0.022
protein autophosphorylation GO:0046777 61 0.022
pyrimidine containing compound catabolic process GO:0072529 3 0.022
cellular homeostasis GO:0019725 240 0.021
pre mirna processing GO:0031054 3 0.021
nuclear import GO:0051170 95 0.021
positive regulation of secretion by cell GO:1903532 114 0.021
lipoprotein metabolic process GO:0042157 43 0.021
dna biosynthetic process GO:0071897 22 0.021
cellular amino acid metabolic process GO:0006520 103 0.021
gene silencing by mirna GO:0035195 10 0.021
divalent metal ion transport GO:0070838 172 0.021

Eif2ak2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.071
disease of cellular proliferation DOID:14566 0 0.071
organ system cancer DOID:0050686 0 0.042