Mus musculus

106 known processes

Cspg4

chondroitin sulfate proteoglycan 4

(Aliases: NG2,AN2,4732461B14Rik)

Cspg4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal muscle organ development GO:0060538 163 0.486
Fly
urogenital system development GO:0001655 261 0.428
Mouse
formation of organ boundary GO:0010160 1 0.194
stem cell development GO:0048864 219 0.190
regulation of cellular ketone metabolic process GO:0010565 66 0.181
synapse organization GO:0050808 125 0.170
extracellular structure organization GO:0043062 148 0.142
skeletal system morphogenesis GO:0048705 203 0.135
regulation of cell motility GO:2000145 236 0.135
renal system development GO:0072001 225 0.133
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.127
developmental growth involved in morphogenesis GO:0060560 138 0.126
cell cell adhesion GO:0098609 41 0.121
heart morphogenesis GO:0003007 178 0.119
positive regulation of cellular amine metabolic process GO:0033240 5 0.111
regulation of cell substrate adhesion GO:0010810 73 0.109
single organism cell adhesion GO:0098602 156 0.104
nitrogen compound transport GO:0071705 271 0.091
lung development GO:0030324 164 0.085
kidney epithelium development GO:0072073 121 0.084
extracellular matrix organization GO:0030198 147 0.082
synaptic transmission GO:0007268 329 0.082
regulation of cellular amine metabolic process GO:0033238 20 0.080
regulation of cellular component biogenesis GO:0044087 181 0.080
Fly
cell substrate adhesion GO:0031589 130 0.077
Mouse
bone development GO:0060348 120 0.076
small gtpase mediated signal transduction GO:0007264 97 0.073
nuclear transport GO:0051169 139 0.073
neuron projection guidance GO:0097485 141 0.072
lateral inhibition GO:0046331 1 0.072
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.070
kidney development GO:0001822 213 0.069
Mouse
amine metabolic process GO:0009308 45 0.069
positive regulation of transferase activity GO:0051347 167 0.069
cell growth GO:0016049 130 0.068
nucleoside phosphate metabolic process GO:0006753 338 0.067
morphogenesis of a branching structure GO:0001763 203 0.066
positive regulation of cell adhesion GO:0045785 80 0.066
stem cell differentiation GO:0048863 268 0.064
protein import into nucleus GO:0006606 95 0.061
organ growth GO:0035265 117 0.061
mesodermal cell migration GO:0008078 4 0.059
positive regulation of growth GO:0045927 104 0.059
ion transmembrane transport GO:0034220 361 0.058
branching morphogenesis of an epithelial tube GO:0048754 159 0.058
nucleobase containing small molecule metabolic process GO:0055086 352 0.058
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.058
negative regulation of synapse assembly GO:0051964 3 0.056
positive regulation of protein kinase activity GO:0045860 144 0.056
cellular amino acid metabolic process GO:0006520 103 0.054
purine containing compound metabolic process GO:0072521 311 0.054
ameboidal type cell migration GO:0001667 128 0.054
oxidation reduction process GO:0055114 342 0.053
regulation of extent of cell growth GO:0061387 52 0.053
cellular ketone metabolic process GO:0042180 84 0.052
metanephric glomerular basement membrane development GO:0072274 1 0.050
regulation of protein kinase activity GO:0045859 232 0.050
multicellular organismal signaling GO:0035637 91 0.050
digestive tract development GO:0048565 190 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
extrinsic apoptotic signaling pathway GO:0097191 126 0.048
positive regulation of cell development GO:0010720 237 0.048
cell adhesion GO:0007155 329 0.047
Mouse
connective tissue development GO:0061448 179 0.047
gland development GO:0048732 330 0.046
sensory perception GO:0007600 245 0.046
regulation of cell adhesion GO:0030155 154 0.046
tissue remodeling GO:0048771 102 0.046
metal ion homeostasis GO:0055065 189 0.045
rac protein signal transduction GO:0016601 13 0.045
cardiac muscle tissue development GO:0048738 130 0.045
actin cytoskeleton organization GO:0030036 220 0.044
epithelial tube morphogenesis GO:0060562 303 0.044
negative regulation of cell proliferation GO:0008285 296 0.044
positive regulation of axon extension GO:0045773 20 0.043
learning GO:0007612 98 0.043
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.043
camera type eye development GO:0043010 266 0.043
ras protein signal transduction GO:0007265 77 0.042
protein localization to nucleus GO:0034504 121 0.041
embryonic organ morphogenesis GO:0048562 276 0.041
rho protein signal transduction GO:0007266 32 0.041
morphogenesis of a branching epithelium GO:0061138 193 0.041
anion transport GO:0006820 177 0.040
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
skeletal system development GO:0001501 356 0.040
regionalization GO:0003002 337 0.039
peptidyl tyrosine phosphorylation GO:0018108 143 0.038
Human
cell type specific apoptotic process GO:0097285 268 0.038
cell fate commitment GO:0045165 210 0.038
Rat
nephron epithelium development GO:0072009 92 0.037
chemotaxis GO:0006935 247 0.037
axon guidance GO:0007411 141 0.037
peptide transport GO:0015833 133 0.037
regulation of hydrolase activity GO:0051336 246 0.036
regulation of cell migration GO:0030334 219 0.036
regulation of neuron apoptotic process GO:0043523 122 0.036
protein hydroxylation GO:0018126 4 0.036
cellular response to acid chemical GO:0071229 68 0.036
organic anion transport GO:0015711 137 0.036
axonogenesis GO:0007409 274 0.035
lateral line system development GO:0048925 1 0.035
nuclear import GO:0051170 95 0.035
respiratory system development GO:0060541 190 0.035
blood vessel morphogenesis GO:0048514 285 0.035
cilium assembly GO:0042384 81 0.034
glucose homeostasis GO:0042593 128 0.034
regulation of transferase activity GO:0051338 263 0.034
renal tubule morphogenesis GO:0061333 72 0.034
cognition GO:0050890 149 0.034
response to growth factor GO:0070848 198 0.034
regulation of cell growth GO:0001558 91 0.033
mesenchyme development GO:0060485 152 0.033
forebrain development GO:0030900 302 0.033
regulation of anatomical structure size GO:0090066 178 0.032
positive regulation of cell growth GO:0030307 33 0.032
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.032
regulation of vasculature development GO:1901342 88 0.032
positive regulation of neuron differentiation GO:0045666 141 0.032
negative regulation of phosphate metabolic process GO:0045936 184 0.032
cation transport GO:0006812 399 0.032
cellular amine metabolic process GO:0044106 44 0.031
ureteric bud development GO:0001657 94 0.031
activation of mapk activity GO:0000187 59 0.031
cellular response to growth factor stimulus GO:0071363 197 0.031
recognition of apoptotic cell GO:0043654 3 0.030
establishment of protein localization to organelle GO:0072594 118 0.030
cation homeostasis GO:0055080 212 0.030
nephron development GO:0072006 109 0.030
negative regulation of growth GO:0045926 99 0.030
neuron projection extension GO:1990138 64 0.030
gastrulation GO:0007369 116 0.030
positive regulation of nervous system development GO:0051962 221 0.029
cell adhesion mediated by integrin GO:0033627 18 0.029
positive regulation of neuron projection development GO:0010976 79 0.029
cytoplasmic transport GO:0016482 234 0.029
endocytosis GO:0006897 168 0.029
transmembrane transport GO:0055085 412 0.028
organophosphate catabolic process GO:0046434 232 0.028
striated muscle tissue development GO:0014706 293 0.028
cellular response to organonitrogen compound GO:0071417 145 0.028
multicellular organism growth GO:0035264 161 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
fasciculation of motor neuron axon GO:0097156 2 0.028
actin filament organization GO:0007015 113 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
cellular chemical homeostasis GO:0055082 215 0.028
neuron death GO:0070997 154 0.027
intracellular protein transport GO:0006886 204 0.027
regulation of cellular response to growth factor stimulus GO:0090287 82 0.027
myeloid leukocyte migration GO:0097529 57 0.027
regulation of neuron projection development GO:0010975 169 0.026
Rat
cell chemotaxis GO:0060326 81 0.026
regulation of angiogenesis GO:0045765 81 0.026
regulation of membrane potential GO:0042391 192 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.026
protein localization to organelle GO:0033365 185 0.026
cell growth involved in cardiac muscle cell development GO:0061049 3 0.026
dorsal ventral axon guidance GO:0033563 3 0.025
nucleotide biosynthetic process GO:0009165 78 0.025
nucleoside phosphate catabolic process GO:1901292 222 0.025
gliogenesis GO:0042063 141 0.025
cellular carbohydrate metabolic process GO:0044262 119 0.025
epithelial cell proliferation GO:0050673 174 0.024
cell matrix adhesion GO:0007160 68 0.024
Mouse
carbohydrate metabolic process GO:0005975 230 0.024
gtp metabolic process GO:0046039 144 0.024
regulation of secretion GO:0051046 274 0.024
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.024
digestive system development GO:0055123 200 0.024
angiogenesis GO:0001525 201 0.024
cellular divalent inorganic cation homeostasis GO:0072503 127 0.024
cartilage development GO:0051216 140 0.024
blood vessel endothelial cell migration GO:0043534 23 0.024
ossification GO:0001503 216 0.024
protein targeting GO:0006605 143 0.024
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.023
ribonucleoside metabolic process GO:0009119 245 0.023
memory GO:0007613 58 0.023
regulation of receptor activity GO:0010469 41 0.023
leukocyte chemotaxis GO:0030595 69 0.023
osteoclast differentiation GO:0030316 62 0.023
exocrine system development GO:0035272 45 0.023
regulation of cardiac muscle tissue development GO:0055024 31 0.023
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.023
nucleocytoplasmic transport GO:0006913 139 0.023
regulation of map kinase activity GO:0043405 120 0.023
regulation of cellular component size GO:0032535 121 0.022
ear morphogenesis GO:0042471 118 0.022
regulation of proteolysis GO:0030162 164 0.022
carbohydrate biosynthetic process GO:0016051 74 0.022
regulation of organelle organization GO:0033043 289 0.022
organic cyclic compound catabolic process GO:1901361 295 0.021
positive regulation of cell substrate adhesion GO:0010811 47 0.021
glial cell migration GO:0008347 7 0.021
epithelial cell development GO:0002064 159 0.021
negative regulation of intracellular signal transduction GO:1902532 167 0.021
physiological cardiac muscle hypertrophy GO:0003301 3 0.021
negative regulation of cellular component organization GO:0051129 194 0.021
Rat
calcium ion homeostasis GO:0055074 127 0.021
regulation of hormone levels GO:0010817 211 0.021
ribose phosphate metabolic process GO:0019693 291 0.020
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.020
regulation of inositol phosphate biosynthetic process GO:0010919 3 0.020
action potential GO:0001508 78 0.020
mesonephric tubule development GO:0072164 94 0.020
olfactory learning GO:0008355 2 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
regulation of axon extension GO:0030516 43 0.019
cation transmembrane transport GO:0098655 266 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
negative regulation of neuron projection regeneration GO:0070571 3 0.019
regulation of neuron differentiation GO:0045664 281 0.019
Rat
spermatogenesis GO:0007283 284 0.019
divalent inorganic cation homeostasis GO:0072507 138 0.019
developmental cell growth GO:0048588 84 0.019
regulation of cell size GO:0008361 72 0.019
regulation of system process GO:0044057 200 0.019
sodium ion export GO:0071436 2 0.019
sensory system development GO:0048880 3 0.019
nucleoside triphosphate catabolic process GO:0009143 205 0.019
regulation of secretion by cell GO:1903530 249 0.019
cellular response to lipid GO:0071396 145 0.019
cellular response to amino acid stimulus GO:0071230 29 0.019
trabecula morphogenesis GO:0061383 40 0.018
aromatic compound catabolic process GO:0019439 286 0.018
regulation of synaptic transmission glutamatergic GO:0051966 19 0.018
muscle cell differentiation GO:0042692 261 0.018
regulation of gtp catabolic process GO:0033124 113 0.018
mesoderm development GO:0007498 100 0.018
regulation of cell projection organization GO:0031344 206 0.018
Rat Fly
cellular lipid metabolic process GO:0044255 323 0.018
nucleotide metabolic process GO:0009117 332 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
myeloid leukocyte differentiation GO:0002573 119 0.018
regulation of ion transmembrane transport GO:0034765 119 0.018
regulation of branching involved in salivary gland morphogenesis by extracellular matrix epithelial cell signaling GO:0060668 1 0.018
respiratory tube development GO:0030323 167 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
muscle tissue development GO:0060537 308 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
regulation of striated muscle cell differentiation GO:0051153 81 0.017
regulation of interleukin 8 production GO:0032677 3 0.017
dendritic spine development GO:0060996 30 0.017
regulation of carbohydrate metabolic process GO:0006109 75 0.017
regulation of kinase activity GO:0043549 249 0.017
brown fat cell differentiation GO:0050873 36 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.017
protein oligomerization GO:0051259 67 0.017
learning or memory GO:0007611 148 0.017
multicellular organismal response to stress GO:0033555 62 0.017
skin development GO:0043588 220 0.017
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.017
regulation of cellular response to stress GO:0080135 159 0.017
transmission of nerve impulse GO:0019226 76 0.017
cardiac muscle cell differentiation GO:0055007 69 0.016
hormone secretion GO:0046879 128 0.016
positive regulation of cell projection organization GO:0031346 95 0.016
Fly
inorganic ion transmembrane transport GO:0098660 234 0.016
protein import GO:0017038 101 0.016
response to acid chemical GO:0001101 111 0.016
regulation of mapk cascade GO:0043408 248 0.016
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 20 0.016
cellular component assembly involved in morphogenesis GO:0010927 139 0.016
negative regulation of protein metabolic process GO:0051248 282 0.016
carbohydrate homeostasis GO:0033500 128 0.016
defense response to other organism GO:0098542 197 0.015
glucose metabolic process GO:0006006 92 0.015
positive regulation of cellular carbohydrate metabolic process GO:0010676 29 0.015
amide transport GO:0042886 138 0.015
protein autophosphorylation GO:0046777 61 0.015
neuron apoptotic process GO:0051402 142 0.015
actin filament polymerization GO:0030041 44 0.015
establishment of organelle localization GO:0051656 122 0.015
sensory perception of chemical stimulus GO:0007606 51 0.015
cell recognition GO:0008037 83 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
epithelium migration GO:0090132 63 0.015
response to oxidative stress GO:0006979 123 0.015
metanephros development GO:0001656 79 0.015
Mouse
cellular glucan metabolic process GO:0006073 32 0.015
gonad development GO:0008406 141 0.015
regulation of organ morphogenesis GO:2000027 144 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
positive regulation of fatty acid oxidation GO:0046321 4 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
fibril organization GO:0097435 2 0.015
response to organonitrogen compound GO:0010243 246 0.015
generation of precursor metabolites and energy GO:0006091 103 0.014
purine ribonucleoside metabolic process GO:0046128 241 0.014
oocyte axis specification GO:0007309 2 0.014
guanosine containing compound catabolic process GO:1901069 144 0.014
fat cell differentiation GO:0045444 160 0.014
developmental maturation GO:0021700 193 0.014
Rat
multicellular organismal homeostasis GO:0048871 164 0.014
heterocycle catabolic process GO:0046700 280 0.014
organelle assembly GO:0070925 177 0.014
regulation of rac protein signal transduction GO:0035020 19 0.014
ribonucleoside triphosphate metabolic process GO:0009199 220 0.014
regulation of protein transport GO:0051223 163 0.014
neutrophil migration GO:1990266 37 0.014
nucleoside catabolic process GO:0009164 206 0.014
dendrite development GO:0016358 115 0.014
mesonephros development GO:0001823 97 0.014
negative regulation of phospholipase activity GO:0010519 4 0.014
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.014
negative regulation of nodal signaling pathway GO:1900108 3 0.014
peptide hormone secretion GO:0030072 109 0.014
cardiac chamber morphogenesis GO:0003206 93 0.013
leukocyte migration GO:0050900 124 0.013
negative regulation of epithelial cell proliferation GO:0050680 64 0.013
regulation of neuronal synaptic plasticity GO:0048168 30 0.013
compound eye development GO:0048749 1 0.013
regulation of muscle tissue development GO:1901861 97 0.013
epithelial cell morphogenesis GO:0003382 41 0.013
fasciculation of sensory neuron axon GO:0097155 3 0.013
nephron tubule development GO:0072080 84 0.013
kidney morphogenesis GO:0060993 83 0.013
Mouse
cardiac muscle tissue growth GO:0055017 37 0.013
response to organic cyclic compound GO:0014070 198 0.013
regulation of glucose metabolic process GO:0010906 60 0.013
wound healing GO:0042060 157 0.013
calcium mediated signaling GO:0019722 46 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
male gamete generation GO:0048232 285 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
cardiac ventricle development GO:0003231 83 0.012
glycoprotein metabolic process GO:0009100 116 0.012
telencephalon development GO:0021537 186 0.012
positive regulation of proteolysis GO:0045862 85 0.012
heart growth GO:0060419 45 0.012
actomyosin structure organization GO:0031032 56 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
positive regulation of muscle tissue development GO:1901863 32 0.012
mesenchymal cell development GO:0014031 93 0.012
protein maturation GO:0051604 176 0.012
endomembrane system organization GO:0010256 147 0.012
regulation of dendritic spine development GO:0060998 22 0.012
notochord cell development GO:0060035 1 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
physiological muscle hypertrophy GO:0003298 3 0.012
regulation of endocytosis GO:0030100 69 0.012
salivary gland development GO:0007431 37 0.012
regulation of cardiac muscle cell differentiation GO:2000725 9 0.012
ear development GO:0043583 200 0.012
Mouse
glomerulus development GO:0032835 40 0.012
extracellular matrix assembly GO:0085029 12 0.012
glial cell differentiation GO:0010001 131 0.012
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.012
polysaccharide metabolic process GO:0005976 39 0.012
myeloid cell differentiation GO:0030099 233 0.012
regulation of organ growth GO:0046620 61 0.012
regulation of tissue remodeling GO:0034103 38 0.012
regulation of transporter activity GO:0032409 57 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
regulation of homeostatic process GO:0032844 182 0.011
mesonephric tubule morphogenesis GO:0072171 63 0.011
membrane organization GO:0061024 245 0.011
nephron epithelium morphogenesis GO:0072088 68 0.011
cardiocyte differentiation GO:0035051 87 0.011
insulin secretion involved in cellular response to glucose stimulus GO:0035773 36 0.011
actin filament bundle assembly GO:0051017 40 0.011
purine containing compound catabolic process GO:0072523 213 0.011
regulation of generation of precursor metabolites and energy GO:0043467 38 0.011
protein polymerization GO:0051258 57 0.011
immune effector process GO:0002252 321 0.011
meiotic nuclear division GO:0007126 115 0.011
single organismal cell cell adhesion GO:0016337 131 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
glucan metabolic process GO:0044042 32 0.011
cell cycle g1 s phase transition GO:0044843 57 0.011
anion transmembrane transport GO:0098656 71 0.011
rna interference GO:0016246 2 0.011
innate immune response GO:0045087 157 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
cellular homeostasis GO:0019725 240 0.011
somatotropin secreting cell differentiation GO:0060126 4 0.011
telencephalon cell migration GO:0022029 55 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
morphogenesis of embryonic epithelium GO:0016331 159 0.011
regulation of body fluid levels GO:0050878 162 0.011
negative regulation of secretion by cell GO:1903531 54 0.011
phosphatidylinositol metabolic process GO:0046488 45 0.011
granulocyte chemotaxis GO:0071621 39 0.011
cellular response to oxidative stress GO:0034599 76 0.011
regulation of neuron death GO:1901214 134 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
receptor mediated endocytosis GO:0006898 51 0.011
negative regulation of cell development GO:0010721 169 0.011
Rat
regulation of cell cycle g1 s phase transition GO:1902806 35 0.011
substrate adhesion dependent cell spreading GO:0034446 30 0.011
purine nucleoside metabolic process GO:0042278 241 0.010
regulation of actin filament length GO:0030832 45 0.010
regulation of rho protein signal transduction GO:0035023 71 0.010
tissue homeostasis GO:0001894 115 0.010
liver development GO:0001889 66 0.010
positive regulation of chemotaxis GO:0050921 38 0.010
regulation of osteoclast differentiation GO:0045670 36 0.010
regulation of wnt signaling pathway GO:0030111 123 0.010
hexose metabolic process GO:0019318 98 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
sensory organ morphogenesis GO:0090596 242 0.010
cell junction organization GO:0034330 77 0.010
glycogen metabolic process GO:0005977 32 0.010
positive regulation of carbohydrate metabolic process GO:0045913 30 0.010
biomineral tissue development GO:0031214 64 0.010
regulation of myeloid leukocyte differentiation GO:0002761 58 0.010

Cspg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.267
disease of anatomical entity DOID:7 0 0.267
musculoskeletal system disease DOID:17 0 0.267
muscle tissue disease DOID:66 0 0.267
myopathy DOID:423 0 0.129
muscular dystrophy DOID:9884 0 0.039
osteochondrodysplasia DOID:2256 0 0.017
bone development disease DOID:0080006 0 0.017
bone disease DOID:0080001 0 0.017
connective tissue disease DOID:65 0 0.017
congenital muscular dystrophy DOID:0050557 0 0.016