Mus musculus

56 known processes

Pgap2

post-GPI attachment to proteins 2

(Aliases: Frag1,C76649,1810006G21Rik)

Pgap2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.069
macromolecule catabolic process GO:0009057 281 0.069
organic cyclic compound catabolic process GO:1901361 295 0.063
cellular macromolecule catabolic process GO:0044265 206 0.058
negative regulation of phosphorylation GO:0042326 166 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.057
heterocycle catabolic process GO:0046700 280 0.056
nucleoside phosphate metabolic process GO:0006753 338 0.056
regulation of mapk cascade GO:0043408 248 0.053
nucleotide metabolic process GO:0009117 332 0.051
cellular ketone metabolic process GO:0042180 84 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
regulation of cellular amine metabolic process GO:0033238 20 0.046
carbohydrate metabolic process GO:0005975 230 0.045
endomembrane system organization GO:0010256 147 0.044
cellular nitrogen compound catabolic process GO:0044270 280 0.043
negative regulation of phosphate metabolic process GO:0045936 184 0.043
negative regulation of cellular protein metabolic process GO:0032269 247 0.043
regulation of cellular response to stress GO:0080135 159 0.042
apoptotic signaling pathway GO:0097190 306 0.041
negative regulation of phosphorus metabolic process GO:0010563 184 0.041
purine nucleotide metabolic process GO:0006163 302 0.039
oxidation reduction process GO:0055114 342 0.039
cellular amine metabolic process GO:0044106 44 0.039
amine metabolic process GO:0009308 45 0.038
aromatic compound catabolic process GO:0019439 286 0.038
protein processing GO:0016485 163 0.036
negative regulation of protein metabolic process GO:0051248 282 0.035
negative regulation of intracellular signal transduction GO:1902532 167 0.035
small gtpase mediated signal transduction GO:0007264 97 0.035
regulation of hydrolase activity GO:0051336 246 0.034
cytokine production GO:0001816 319 0.034
intracellular protein transport GO:0006886 204 0.033
homeostasis of number of cells GO:0048872 210 0.032
purine nucleoside metabolic process GO:0042278 241 0.031
carbohydrate derivative catabolic process GO:1901136 231 0.031
epithelial tube morphogenesis GO:0060562 303 0.031
regulation of transferase activity GO:0051338 263 0.031
ribose phosphate metabolic process GO:0019693 291 0.030
regulation of cellular catabolic process GO:0031329 242 0.030
mapk cascade GO:0000165 281 0.030
membrane organization GO:0061024 245 0.030
compound eye development GO:0048749 1 0.030
protein maturation GO:0051604 176 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
ras protein signal transduction GO:0007265 77 0.029
chromatin organization GO:0006325 206 0.029
dna metabolic process GO:0006259 303 0.028
organonitrogen compound catabolic process GO:1901565 264 0.027
purine nucleotide catabolic process GO:0006195 211 0.027
mitochondrion organization GO:0007005 134 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
carbohydrate derivative biosynthetic process GO:1901137 183 0.027
cell type specific apoptotic process GO:0097285 268 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
cytoplasmic transport GO:0016482 234 0.027
chromatin modification GO:0016568 187 0.026
nucleotide catabolic process GO:0009166 217 0.026
nitrogen compound transport GO:0071705 271 0.026
maintenance of location GO:0051235 89 0.026
regulation of cytokine production GO:0001817 266 0.026
positive regulation of protein modification process GO:0031401 299 0.026
organophosphate catabolic process GO:0046434 232 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
regulation of membrane potential GO:0042391 192 0.025
cation transmembrane transport GO:0098655 266 0.025
cellular response to dna damage stimulus GO:0006974 207 0.025
neuron death GO:0070997 154 0.025
negative regulation of protein modification process GO:0031400 163 0.025
neural tube development GO:0021915 160 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
negative regulation of cellular amine metabolic process GO:0033239 1 0.025
response to organonitrogen compound GO:0010243 246 0.024
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.024
negative regulation of cell proliferation GO:0008285 296 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
intrinsic apoptotic signaling pathway GO:0097193 132 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
cellular response to growth factor stimulus GO:0071363 197 0.024
regulation of secretion GO:0051046 274 0.024
transmembrane transport GO:0055085 412 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
regulation of kinase activity GO:0043549 249 0.024
protein modification by small protein conjugation GO:0032446 187 0.023
response to molecule of bacterial origin GO:0002237 143 0.023
response to oxidative stress GO:0006979 123 0.023
positive regulation of proteolysis GO:0045862 85 0.023
organonitrogen compound biosynthetic process GO:1901566 192 0.022
leukocyte differentiation GO:0002521 342 0.022
purine nucleoside triphosphate catabolic process GO:0009146 203 0.022
purine containing compound catabolic process GO:0072523 213 0.022
regulation of lymphocyte activation GO:0051249 240 0.022
response to growth factor GO:0070848 198 0.022
lateral inhibition GO:0046331 1 0.022
regulation of t cell activation GO:0050863 170 0.021
regulation of protein kinase activity GO:0045859 232 0.021
purine containing compound metabolic process GO:0072521 311 0.021
protein glycosylation GO:0006486 55 0.021
negative regulation of immune system process GO:0002683 209 0.021
response to lipopolysaccharide GO:0032496 128 0.021
nucleoside triphosphate metabolic process GO:0009141 230 0.020
regulation of cell activation GO:0050865 289 0.020
cellular lipid metabolic process GO:0044255 323 0.020
negative regulation of molecular function GO:0044092 258 0.020
positive regulation of protein phosphorylation GO:0001934 242 0.020
positive regulation of apoptotic process GO:0043065 217 0.020
peptidyl amino acid modification GO:0018193 336 0.020
purine nucleoside catabolic process GO:0006152 205 0.020
regulation of ras protein signal transduction GO:0046578 114 0.020
myeloid cell differentiation GO:0030099 233 0.020
regulation of anatomical structure size GO:0090066 178 0.019
regionalization GO:0003002 337 0.019
lymphocyte proliferation GO:0046651 164 0.019
lung development GO:0030324 164 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
respiratory tube development GO:0030323 167 0.019
nucleoside metabolic process GO:0009116 246 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
regulation of protein serine threonine kinase activity GO:0071900 157 0.019
nucleoside catabolic process GO:0009164 206 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
protein catabolic process GO:0030163 221 0.018
regulation of proteolysis GO:0030162 164 0.018
gland development GO:0048732 330 0.018
regulation of protein localization GO:0032880 231 0.018
ribonucleoside metabolic process GO:0009119 245 0.017
respiratory system development GO:0060541 190 0.017
cell adhesion GO:0007155 329 0.017
transmission of nerve impulse GO:0019226 76 0.017
multicellular organismal signaling GO:0035637 91 0.017
spermatogenesis GO:0007283 284 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
lipid localization GO:0010876 126 0.017
ribonucleotide catabolic process GO:0009261 208 0.017
cellular protein catabolic process GO:0044257 155 0.017
regulation of organelle organization GO:0033043 289 0.017
neural tube formation GO:0001841 108 0.017
synaptic transmission GO:0007268 329 0.017
action potential GO:0001508 78 0.017
dna repair GO:0006281 107 0.017
cellular response to lipid GO:0071396 145 0.017
cytokine mediated signaling pathway GO:0019221 115 0.017
methylation GO:0032259 134 0.017
macromolecule glycosylation GO:0043413 55 0.017
regulation of cell projection organization GO:0031344 206 0.017
sensory perception GO:0007600 245 0.017
regulation of cell cycle GO:0051726 281 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.016
tube formation GO:0035148 140 0.016
negative regulation of cellular component organization GO:0051129 194 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
coenzyme metabolic process GO:0006732 52 0.016
gene silencing by mirna GO:0035195 10 0.016
skin development GO:0043588 220 0.016
positive regulation of cell death GO:0010942 224 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
glycoprotein metabolic process GO:0009100 116 0.016
blood circulation GO:0008015 195 0.016
positive regulation of hydrolase activity GO:0051345 148 0.016
leukocyte proliferation GO:0070661 172 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
protein ubiquitination GO:0016567 171 0.016
blood vessel morphogenesis GO:0048514 285 0.016
morphogenesis of a branching epithelium GO:0061138 193 0.016
cell substrate adhesion GO:0031589 130 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.016
neuron apoptotic process GO:0051402 142 0.016
epithelial tube formation GO:0072175 130 0.016
muscle tissue development GO:0060537 308 0.015
neuronal action potential GO:0019228 54 0.015
positive regulation of protein transport GO:0051222 93 0.015
immune effector process GO:0002252 321 0.015
histone modification GO:0016570 159 0.015
embryonic epithelial tube formation GO:0001838 130 0.015
regulation of t cell proliferation GO:0042129 92 0.015
fat cell differentiation GO:0045444 160 0.015
cellularization GO:0007349 1 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
regulation of purine nucleotide metabolic process GO:1900542 169 0.015
muscle cell differentiation GO:0042692 261 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
rna processing GO:0006396 105 0.015
regulation of cell motility GO:2000145 236 0.015
regulation of protein transport GO:0051223 163 0.015
male gamete generation GO:0048232 285 0.014
urogenital system development GO:0001655 261 0.014
striated muscle tissue development GO:0014706 293 0.014
positive regulation of apoptotic signaling pathway GO:2001235 95 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
organelle localization GO:0051640 179 0.014
ossification GO:0001503 216 0.014
negative regulation of transferase activity GO:0051348 85 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
glycosylation GO:0070085 62 0.014
response to organic cyclic compound GO:0014070 198 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
glycoprotein biosynthetic process GO:0009101 89 0.014
sulfur compound metabolic process GO:0006790 100 0.014
developmental maturation GO:0021700 193 0.014
actin polymerization or depolymerization GO:0008154 54 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
innate immune response GO:0045087 157 0.014
chemotaxis GO:0006935 247 0.014
macromolecule deacylation GO:0098732 37 0.014
regulation of peptidase activity GO:0052547 96 0.014
negative regulation of kinase activity GO:0033673 81 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
apoptotic mitochondrial changes GO:0008637 48 0.013
regulation of lymphocyte proliferation GO:0050670 117 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
protein polymerization GO:0051258 57 0.013
actin cytoskeleton organization GO:0030036 220 0.013
negative regulation of apoptotic signaling pathway GO:2001234 104 0.013
retrograde transport endosome to golgi GO:0042147 2 0.013
circulatory system process GO:0003013 197 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
cellular protein complex assembly GO:0043623 116 0.013
regulation of neuron death GO:1901214 134 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
negative regulation of nervous system development GO:0051961 156 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of lamellipodium assembly GO:0010591 3 0.013
cation transport GO:0006812 399 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
ion transmembrane transport GO:0034220 361 0.013
regulation of protein catabolic process GO:0042176 108 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
regulation of cell migration GO:0030334 219 0.013
macromolecule methylation GO:0043414 120 0.012
regulation of map kinase activity GO:0043405 120 0.012
inflammatory response GO:0006954 244 0.012
plasma membrane organization GO:0007009 90 0.012
single organism cell adhesion GO:0098602 156 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
actin filament polymerization GO:0030041 44 0.012
anion transport GO:0006820 177 0.012
positive regulation of nervous system development GO:0051962 221 0.012
rho protein signal transduction GO:0007266 32 0.012
negative regulation of organelle organization GO:0010639 90 0.012
negative regulation of cell cycle GO:0045786 123 0.012
interleukin 8 production GO:0032637 4 0.012
t cell proliferation GO:0042098 120 0.012
cellular homeostasis GO:0019725 240 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
positive regulation of cytokine production GO:0001819 174 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
endocytosis GO:0006897 168 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
lipid transport GO:0006869 98 0.012
wnt signaling pathway GO:0016055 188 0.012
t cell activation GO:0042110 289 0.012
protein localization to membrane GO:0072657 108 0.012
myeloid cell homeostasis GO:0002262 114 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.011
regulation of defense response GO:0031347 233 0.011
negative regulation of cellular catabolic process GO:0031330 47 0.011
establishment of vesicle localization GO:0051650 81 0.011
establishment of protein localization to membrane GO:0090150 54 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
response to extracellular stimulus GO:0009991 127 0.011
mrna metabolic process GO:0016071 84 0.011
stress activated mapk cascade GO:0051403 80 0.011
forebrain development GO:0030900 302 0.011
nuclear transport GO:0051169 139 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
protein localization to organelle GO:0033365 185 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
metal ion homeostasis GO:0055065 189 0.011
multicellular organism growth GO:0035264 161 0.011
cellular response to external stimulus GO:0071496 88 0.011
spermatid development GO:0007286 108 0.011
stress activated protein kinase signaling cascade GO:0031098 81 0.011
pole plasm assembly GO:0007315 2 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
angiogenesis GO:0001525 201 0.011
camera type eye development GO:0043010 266 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
regulation of muscle tissue development GO:1901861 97 0.011
regulation of homeostatic process GO:0032844 182 0.011
covalent chromatin modification GO:0016569 163 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
ribonucleoside catabolic process GO:0042454 206 0.011
guanosine containing compound metabolic process GO:1901068 144 0.011
cellular response to oxidative stress GO:0034599 76 0.011
positive regulation of organelle organization GO:0010638 128 0.011
microtubule based process GO:0007017 236 0.011
regulation of multi organism process GO:0043900 111 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
b cell activation GO:0042113 161 0.010
protein localization to plasma membrane GO:0072659 57 0.010
leukocyte apoptotic process GO:0071887 71 0.010
positive regulation of cell development GO:0010720 237 0.010
response to oxygen levels GO:0070482 62 0.010
modification dependent protein catabolic process GO:0019941 133 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
epidermis development GO:0008544 187 0.010
response to acid chemical GO:0001101 111 0.010
exocytosis GO:0006887 121 0.010
ameboidal type cell migration GO:0001667 128 0.010
maternal determination of anterior posterior axis embryo GO:0008358 2 0.010
cellular carbohydrate metabolic process GO:0044262 119 0.010
epithelial cell proliferation GO:0050673 174 0.010
response to nutrient levels GO:0031667 109 0.010
positive regulation of mapk cascade GO:0043410 170 0.010
ensheathment of neurons GO:0007272 76 0.010
leukocyte homeostasis GO:0001776 79 0.010
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.010
myelination GO:0042552 74 0.010

Pgap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.016
central nervous system disease DOID:331 0 0.012
inherited metabolic disorder DOID:655 0 0.011
cardiovascular system disease DOID:1287 0 0.010
brain disease DOID:936 0 0.010