Mus musculus

0 known processes

Plec

plectin

(Aliases: Plec1,AU042537,AA591047,EBS1,PLTN,PCN)

Plec biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.843
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.672
Mouse
actin cytoskeleton organization GO:0030036 220 0.652
muscle cell development GO:0055001 133 0.446
striated muscle tissue development GO:0014706 293 0.443
muscle tissue development GO:0060537 308 0.387
positive regulation of cell projection organization GO:0031346 95 0.386
Fly
ribonucleotide catabolic process GO:0009261 208 0.373
Mouse
myotube differentiation GO:0014902 105 0.354
skeletal muscle organ development GO:0060538 163 0.338
protein localization to membrane GO:0072657 108 0.333
Mouse
locomotory behavior GO:0007626 195 0.313
regulation of organelle organization GO:0033043 289 0.304
Mouse Fly
cellular component assembly involved in morphogenesis GO:0010927 139 0.289
response to growth factor GO:0070848 198 0.288
muscle cell differentiation GO:0042692 261 0.287
heterocycle catabolic process GO:0046700 280 0.284
Mouse
striated muscle cell development GO:0055002 125 0.274
regulation of cell motility GO:2000145 236 0.271
Mouse
kidney development GO:0001822 213 0.265
urogenital system development GO:0001655 261 0.264
actomyosin structure organization GO:0031032 56 0.259
cellular amine metabolic process GO:0044106 44 0.252
cardiocyte differentiation GO:0035051 87 0.252
regulation of cytoskeleton organization GO:0051493 122 0.241
Mouse Fly
muscle system process GO:0003012 141 0.231
cell substrate adhesion GO:0031589 130 0.227
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.227
renal system development GO:0072001 225 0.213
regulation of rho protein signal transduction GO:0035023 71 0.208
regulation of mapk cascade GO:0043408 248 0.201
cell matrix adhesion GO:0007160 68 0.198
Mouse
cell junction organization GO:0034330 77 0.198
Human Mouse
negative regulation of molecular function GO:0044092 258 0.197
axon guidance GO:0007411 141 0.197
Fly
myeloid cell differentiation GO:0030099 233 0.188
positive regulation of nervous system development GO:0051962 221 0.187
Fly
mitotic cell cycle GO:0000278 195 0.187
small gtpase mediated signal transduction GO:0007264 97 0.187
purine ribonucleoside catabolic process GO:0046130 205 0.186
Mouse
glycosyl compound catabolic process GO:1901658 206 0.184
Mouse
myofibril assembly GO:0030239 34 0.184
cellular ketone metabolic process GO:0042180 84 0.181
gland development GO:0048732 330 0.180
striated muscle myosin thick filament assembly GO:0071688 1 0.177
cardiac muscle cell differentiation GO:0055007 69 0.175
axon cargo transport GO:0008088 33 0.175
Mouse
actin filament organization GO:0007015 113 0.173
cytoskeleton dependent intracellular transport GO:0030705 50 0.169
Mouse
regulation of hydrolase activity GO:0051336 246 0.162
rho protein signal transduction GO:0007266 32 0.160
nucleotide catabolic process GO:0009166 217 0.159
Mouse
glycosyl compound metabolic process GO:1901657 246 0.158
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.154
regulation of skeletal muscle fiber development GO:0048742 36 0.153
nucleoside catabolic process GO:0009164 206 0.149
Mouse
myosin filament assembly GO:0031034 2 0.149
protein localization to plasma membrane GO:0072659 57 0.138
positive regulation of neuron differentiation GO:0045666 141 0.137
Fly
organelle assembly GO:0070925 177 0.135
nucleotide metabolic process GO:0009117 332 0.130
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.130
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.130
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.130
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.128
purine nucleoside triphosphate catabolic process GO:0009146 203 0.127
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.127
Mouse
amine metabolic process GO:0009308 45 0.125
mitotic cell cycle process GO:1903047 159 0.125
cardiac muscle tissue development GO:0048738 130 0.120
syncytium formation GO:0006949 43 0.119
regulation of cellular component biogenesis GO:0044087 181 0.118
Mouse Fly
positive regulation of protein modification process GO:0031401 299 0.117
cellular response to growth factor stimulus GO:0071363 197 0.116
synaptic transmission GO:0007268 329 0.116
aromatic compound catabolic process GO:0019439 286 0.114
Mouse
leukocyte differentiation GO:0002521 342 0.114
purine nucleoside triphosphate metabolic process GO:0009144 226 0.113
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.112
Mouse
cellular amino acid metabolic process GO:0006520 103 0.110
macromolecule catabolic process GO:0009057 281 0.110
microtubule based transport GO:0010970 50 0.109
Mouse
cellular response to salt stress GO:0071472 1 0.106
organelle fission GO:0048285 170 0.105
microtubule cytoskeleton organization GO:0000226 157 0.105
Mouse Fly
positive regulation of growth GO:0045927 104 0.105
Fly
nucleoside triphosphate catabolic process GO:0009143 205 0.105
Mouse
lymphocyte differentiation GO:0030098 242 0.104
purine ribonucleotide catabolic process GO:0009154 208 0.103
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.103
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.102
purine ribonucleoside metabolic process GO:0046128 241 0.100
Mouse
axonogenesis GO:0007409 274 0.099
Mouse Fly
regulation of cell migration GO:0030334 219 0.097
Mouse
protein maturation GO:0051604 176 0.094
muscle contraction GO:0006936 101 0.094
i kappab kinase nf kappab signaling GO:0007249 85 0.093
extracellular matrix organization GO:0030198 147 0.092
fat cell differentiation GO:0045444 160 0.092
cell substrate junction assembly GO:0007044 24 0.092
Human Mouse
cellular response to sterol depletion GO:0071501 4 0.091
adult behavior GO:0030534 135 0.091
regulation of cell projection organization GO:0031344 206 0.090
Fly
regulation of actin cytoskeleton organization GO:0032956 84 0.090
lymphocyte proliferation GO:0046651 164 0.090
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.090
Fly
substrate dependent cell migration cell extension GO:0006930 4 0.089
membrane organization GO:0061024 245 0.089
Mouse
regulation of neuron differentiation GO:0045664 281 0.086
Fly
female meiosis chromosome segregation GO:0016321 1 0.086
photoreceptor cell differentiation GO:0046530 52 0.085
cell junction assembly GO:0034329 52 0.085
Human Mouse
blood circulation GO:0008015 195 0.083
actin filament based movement GO:0030048 23 0.082
circulatory system process GO:0003013 197 0.082
apoptotic signaling pathway GO:0097190 306 0.081
regulation of neuron projection development GO:0010975 169 0.081
Fly
sarcomere organization GO:0045214 24 0.080
negative regulation of protein phosphorylation GO:0001933 126 0.079
negative regulation of cell cycle GO:0045786 123 0.079
substrate dependent cell migration GO:0006929 18 0.079
regulation of stress fiber assembly GO:0051492 15 0.078
skeletal muscle fiber development GO:0048741 58 0.078
response to transforming growth factor beta GO:0071559 88 0.078
ribonucleoside metabolic process GO:0009119 245 0.078
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.077
regulation of nucleoside metabolic process GO:0009118 130 0.077
gliogenesis GO:0042063 141 0.076
negative regulation of phosphorus metabolic process GO:0010563 184 0.076
purine nucleoside metabolic process GO:0042278 241 0.076
Mouse
protein targeting GO:0006605 143 0.074
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.074
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.073
transmembrane transport GO:0055085 412 0.073
digestive system development GO:0055123 200 0.073
Mouse
positive regulation of neuron projection development GO:0010976 79 0.073
Fly
regulation of protein processing GO:0070613 96 0.072
regulation of purine nucleotide catabolic process GO:0033121 122 0.072
regulation of cellular catabolic process GO:0031329 242 0.072
negative regulation of protein metabolic process GO:0051248 282 0.071
positive regulation of cell development GO:0010720 237 0.071
Fly
epithelial cell development GO:0002064 159 0.071
negative regulation of intracellular signal transduction GO:1902532 167 0.070
purine ribonucleotide metabolic process GO:0009150 290 0.070
Mouse
positive regulation of glial cell proliferation GO:0060252 4 0.070
leukocyte proliferation GO:0070661 172 0.069
respiratory tube development GO:0030323 167 0.068
organonitrogen compound catabolic process GO:1901565 264 0.067
Mouse
regulation of cell growth GO:0001558 91 0.067
Fly
respiratory system development GO:0060541 190 0.066
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.066
neuron projection guidance GO:0097485 141 0.065
Fly
protein processing GO:0016485 163 0.065
rac protein signal transduction GO:0016601 13 0.065
meiotic nuclear division GO:0007126 115 0.064
positive regulation of protein phosphorylation GO:0001934 242 0.064
regulation of apoptotic signaling pathway GO:2001233 197 0.064
mesoderm development GO:0007498 100 0.063
Mouse
glial cell fate determination GO:0007403 3 0.062
regulation of embryonic development GO:0045995 71 0.062
negative regulation of apoptotic signaling pathway GO:2001234 104 0.062
negative regulation of phosphorylation GO:0042326 166 0.062
microtubule based process GO:0007017 236 0.062
Mouse Fly
negative regulation of immune system process GO:0002683 209 0.060
mapk cascade GO:0000165 281 0.060
regulation of anatomical structure size GO:0090066 178 0.060
Fly
regionalization GO:0003002 337 0.059
striated muscle contraction GO:0006941 45 0.059
protein catabolic process GO:0030163 221 0.058
regulation of nucleotide catabolic process GO:0030811 122 0.058
regulation of defense response GO:0031347 233 0.058
extracellular structure organization GO:0043062 148 0.058
regulation of mitotic cell cycle GO:0007346 126 0.057
wound healing GO:0042060 157 0.056
Mouse
cell adhesion GO:0007155 329 0.056
Mouse
negative regulation of cellular component organization GO:0051129 194 0.055
Fly
t cell activation GO:0042110 289 0.055
t cell proliferation GO:0042098 120 0.055
guanosine containing compound metabolic process GO:1901068 144 0.055
microtubule based movement GO:0007018 84 0.055
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.055
Fly
regulation of actin filament based process GO:0032970 99 0.054
response to molecule of bacterial origin GO:0002237 143 0.054
modification dependent macromolecule catabolic process GO:0043632 133 0.054
cell cell junction organization GO:0045216 72 0.054
Mouse
glial cell differentiation GO:0010001 131 0.054
myotube cell development GO:0014904 60 0.053
myeloid leukocyte differentiation GO:0002573 119 0.053
negative regulation of ras protein signal transduction GO:0046580 18 0.053
purine nucleotide metabolic process GO:0006163 302 0.053
Mouse
regulation of meiotic cell cycle GO:0051445 34 0.052
purine nucleoside catabolic process GO:0006152 205 0.052
Mouse
immune response regulating signaling pathway GO:0002764 125 0.052
negative regulation of hydrolase activity GO:0051346 71 0.051
response to metal ion GO:0010038 47 0.050
regulation of cellular response to growth factor stimulus GO:0090287 82 0.049
mitotic nuclear division GO:0007067 48 0.049
peptidyl serine modification GO:0018209 83 0.049
endomembrane system organization GO:0010256 147 0.049
negative regulation of protein maturation GO:1903318 79 0.049
positive regulation of cytoplasmic transport GO:1903651 40 0.049
positive regulation of cell migration GO:0030335 109 0.049
protein localization to nuclear envelope GO:0090435 2 0.049
gastrulation GO:0007369 116 0.049
Mouse
purine containing compound catabolic process GO:0072523 213 0.048
Mouse
regulation of erk1 and erk2 cascade GO:0070372 71 0.048
regulation of purine nucleotide metabolic process GO:1900542 169 0.047
ion transmembrane transport GO:0034220 361 0.047
regulation of fat cell differentiation GO:0045598 81 0.046
nucleoside metabolic process GO:0009116 246 0.046
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.046
Mouse
ribonucleotide metabolic process GO:0009259 291 0.046
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.046
negative regulation of peptidase activity GO:0010466 46 0.046
cation transmembrane transport GO:0098655 266 0.046
regulation of cell activation GO:0050865 289 0.046
single organism cell adhesion GO:0098602 156 0.045
regulation of nucleotide metabolic process GO:0006140 169 0.045
regulation of cell adhesion GO:0030155 154 0.045
Mouse
regulation of cell cycle GO:0051726 281 0.045
regulation of cardiac cell fate specification GO:2000043 1 0.045
meiotic cell cycle GO:0051321 122 0.044
regulation of ion transport GO:0043269 215 0.044
protein import into nucleus GO:0006606 95 0.044
adherens junction organization GO:0034332 28 0.044
Mouse
negative regulation of protein processing GO:0010955 79 0.044
nucleus localization GO:0051647 20 0.044
purine nucleotide catabolic process GO:0006195 211 0.043
Mouse
stem cell differentiation GO:0048863 268 0.043
erk1 and erk2 cascade GO:0070371 77 0.043
inflammatory response GO:0006954 244 0.043
heart contraction GO:0060047 93 0.042
regulation of schwann cell proliferation GO:0010624 2 0.042
ribonucleoside catabolic process GO:0042454 206 0.042
Mouse
homeostasis of number of cells GO:0048872 210 0.042
plasma membrane organization GO:0007009 90 0.042
positive regulation of transcription via serum response element binding GO:0010735 1 0.041
protein localization to nucleus GO:0034504 121 0.041
adult locomotory behavior GO:0008344 91 0.041
actin filament bundle assembly GO:0051017 40 0.041
g1 s transition of mitotic cell cycle GO:0000082 57 0.041
regulation of innate immune response GO:0045088 91 0.040
regulation of cardioblast differentiation GO:0051890 3 0.040
maintenance of location GO:0051235 89 0.040
neuron migration GO:0001764 122 0.040
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
peripheral nervous system neuron axonogenesis GO:0048936 3 0.039
placenta development GO:0001890 140 0.039
regulation of protein transport GO:0051223 163 0.039
blood vessel morphogenesis GO:0048514 285 0.039
sequestering of calcium ion GO:0051208 18 0.039
stress activated mapk cascade GO:0051403 80 0.039
midgut development GO:0007494 4 0.038
regulation of cytoplasmic transport GO:1903649 112 0.038
endocytosis GO:0006897 168 0.038
purine nucleoside monophosphate catabolic process GO:0009128 58 0.038
Mouse
response to lipopolysaccharide GO:0032496 128 0.038
syncytium formation by plasma membrane fusion GO:0000768 42 0.038
positive regulation of cell motility GO:2000147 116 0.038
regulation of protein localization GO:0032880 231 0.038
dendrite development GO:0016358 115 0.037
Fly
regulation of lymphocyte activation GO:0051249 240 0.037
gtp metabolic process GO:0046039 144 0.037
positive regulation of cell substrate adhesion GO:0010811 47 0.037
embryonic organ morphogenesis GO:0048562 276 0.036
response to inorganic substance GO:0010035 96 0.036
single organism nuclear import GO:1902593 95 0.036
cell growth GO:0016049 130 0.036
Fly
nuclear division GO:0000280 158 0.036
regulation of cell cycle process GO:0010564 160 0.035
regulation of protein targeting GO:1903533 61 0.035
gtp catabolic process GO:0006184 143 0.035
regulation of reproductive process GO:2000241 66 0.035
extrinsic apoptotic signaling pathway GO:0097191 126 0.035
regulation of secretion GO:0051046 274 0.035
cellular response to lipopolysaccharide GO:0071222 77 0.035
nuclear transport GO:0051169 139 0.035
mesodermal cell migration GO:0008078 4 0.035
mesenchymal cell development GO:0014031 93 0.034
calcium ion homeostasis GO:0055074 127 0.034
glycoprotein biosynthetic process GO:0009101 89 0.034
regulation of striated muscle cell differentiation GO:0051153 81 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.034
Mouse
muscle cell apoptotic process GO:0010657 18 0.033
positive regulation of map kinase activity GO:0043406 84 0.033
regulation of t cell activation GO:0050863 170 0.033
negative regulation of cell migration GO:0030336 59 0.033
regulation of chromatin modification GO:1903308 57 0.033
cation transport GO:0006812 399 0.032
positive regulation of necrotic cell death GO:0010940 1 0.032
gonad development GO:0008406 141 0.032
establishment of protein localization to organelle GO:0072594 118 0.032
Mouse
localization within membrane GO:0051668 4 0.032
embryonic placenta development GO:0001892 98 0.031
regulation of protein maturation GO:1903317 96 0.031
regulation of chromosome organization GO:0033044 83 0.031
cytokine mediated signaling pathway GO:0019221 115 0.031
cardiac muscle cell development GO:0055013 39 0.031
multi multicellular organism process GO:0044706 109 0.031
Rat
regulation of actin filament polymerization GO:0030833 38 0.031
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.031
positive regulation of organelle organization GO:0010638 128 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
t cell differentiation in thymus GO:0033077 77 0.031
lung development GO:0030324 164 0.031
protein autophosphorylation GO:0046777 61 0.031
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.031
Fly
germ cell development GO:0007281 185 0.030
modification dependent protein catabolic process GO:0019941 133 0.030
regulation of proteolysis GO:0030162 164 0.030
purine containing compound metabolic process GO:0072521 311 0.030
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.030
positive regulation of mapk cascade GO:0043410 170 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
muscle fiber development GO:0048747 76 0.030
anion transport GO:0006820 177 0.030
regulation of establishment of protein localization GO:0070201 181 0.030
ribonucleoside monophosphate metabolic process GO:0009161 80 0.029
Mouse
intracellular protein transport GO:0006886 204 0.029
Mouse
nucleocytoplasmic transport GO:0006913 139 0.029
camera type eye development GO:0043010 266 0.029
wnt signaling pathway GO:0016055 188 0.029
Mouse
response to epidermal growth factor GO:0070849 4 0.029
regulation of myeloid leukocyte differentiation GO:0002761 58 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
Mouse
retina development in camera type eye GO:0060041 119 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.029
g protein coupled receptor signaling pathway GO:0007186 243 0.028
cytoplasmic transport GO:0016482 234 0.028
Mouse
adherens junction assembly GO:0034333 22 0.028
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.028
blood vessel endothelial cell migration GO:0043534 23 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
establishment of mitochondrion localization GO:0051654 4 0.027
innate immune response GO:0045087 157 0.027
establishment of endothelial blood brain barrier GO:0014045 3 0.027
epithelial cell proliferation GO:0050673 174 0.027
cardiac cell fate specification GO:0060912 2 0.027
regulation of protein binding GO:0043393 60 0.027
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.027
regulation of actin filament bundle assembly GO:0032231 18 0.027
cartilage development GO:0051216 140 0.027
cellular response to abiotic stimulus GO:0071214 56 0.027
protein localization to organelle GO:0033365 185 0.027
Mouse
negative regulation of mitotic cell cycle GO:0045930 58 0.027
oocyte development GO:0048599 33 0.027
negative regulation of cell motility GO:2000146 61 0.027
regulation of lamellipodium morphogenesis GO:2000392 1 0.027
skeletal system development GO:0001501 356 0.027
response to organic cyclic compound GO:0014070 198 0.026
sensory perception GO:0007600 245 0.026
mitotic cytokinesis GO:0000281 4 0.026
stress activated protein kinase signaling cascade GO:0031098 81 0.026
compound eye development GO:0048749 1 0.026
spermatogenesis GO:0007283 284 0.026
negative regulation of proteolysis GO:0045861 74 0.025
striated muscle cell apoptotic process GO:0010658 12 0.025
organelle localization GO:0051640 179 0.025
heart process GO:0003015 94 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.025
regulation of muscle system process GO:0090257 80 0.025
cellular homeostasis GO:0019725 240 0.025
action potential GO:0001508 78 0.025
male gamete generation GO:0048232 285 0.025
calcium ion transport GO:0006816 159 0.025
negative regulation of cell development GO:0010721 169 0.025
angiogenesis GO:0001525 201 0.024
guanosine containing compound catabolic process GO:1901069 144 0.024
somitogenesis GO:0001756 69 0.024
positive regulation of ion transport GO:0043270 65 0.024
chemotaxis GO:0006935 247 0.024
Fly
divalent metal ion transport GO:0070838 172 0.024
organophosphate catabolic process GO:0046434 232 0.024
Mouse
female gamete generation GO:0007292 74 0.024
cellular response to organonitrogen compound GO:0071417 145 0.024
regulation of histone modification GO:0031056 56 0.024
regulation of rho gtpase activity GO:0032319 58 0.024
myeloid cell homeostasis GO:0002262 114 0.023
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.023
regulation of synaptic plasticity GO:0048167 87 0.023
cilium morphogenesis GO:0060271 102 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
sequestering of metal ion GO:0051238 19 0.023
leukocyte migration GO:0050900 124 0.023
ribose phosphate metabolic process GO:0019693 291 0.022
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.022
schwann cell proliferation GO:0014010 2 0.022
lymphocyte homeostasis GO:0002260 64 0.022
exocrine system development GO:0035272 45 0.022
regulation of peptidyl lysine acetylation GO:2000756 22 0.022
cardiac myofibril assembly GO:0055003 12 0.022
oviduct development GO:0060066 3 0.022
digestive tract development GO:0048565 190 0.022
Mouse
positive regulation of intracellular transport GO:0032388 70 0.022
cellular response to biotic stimulus GO:0071216 92 0.022
formation of radial glial scaffolds GO:0021943 4 0.022
response to fibroblast growth factor GO:0071774 47 0.022
integrin mediated signaling pathway GO:0007229 27 0.022
regulation of intracellular protein transport GO:0033157 82 0.022
regulation of cellular component size GO:0032535 121 0.022
Fly
t cell differentiation GO:0030217 174 0.022
mitochondrion organization GO:0007005 134 0.022
positive regulation of ras gtpase activity GO:0032320 65 0.022
dephosphorylation GO:0016311 129 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.021
Mouse
srebp signaling pathway GO:0032933 4 0.021
positive regulation of cell adhesion GO:0045785 80 0.021
small molecule biosynthetic process GO:0044283 132 0.021
immune response activating signal transduction GO:0002757 116 0.021
cell type specific apoptotic process GO:0097285 268 0.021
regulation of t cell proliferation GO:0042129 92 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
negative regulation of rho protein signal transduction GO:0035024 7 0.021
cardiac muscle cell apoptotic process GO:0010659 10 0.021
exocytosis GO:0006887 121 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.021
ovulation GO:0030728 15 0.020
cellular response to cytokine stimulus GO:0071345 189 0.020
single organismal cell cell adhesion GO:0016337 131 0.020
purine nucleoside monophosphate metabolic process GO:0009126 81 0.020
Mouse
regulation of cell division GO:0051302 76 0.020
connective tissue development GO:0061448 179 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
response to amino acid GO:0043200 37 0.020
lamellipodium organization GO:0097581 29 0.020
negative regulation of protein modification process GO:0031400 163 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
lens development in camera type eye GO:0002088 62 0.020
protein import GO:0017038 101 0.020
single fertilization GO:0007338 82 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
focal adhesion assembly GO:0048041 19 0.019
Mouse
divalent inorganic cation transport GO:0072511 178 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.019
cellular calcium ion homeostasis GO:0006874 119 0.019
cell substrate adherens junction assembly GO:0007045 19 0.019
Mouse
osteoclast differentiation GO:0030316 62 0.019
positive regulation of binding GO:0051099 49 0.019
dendritic spine maintenance GO:0097062 4 0.019
memory GO:0007613 58 0.019
mitochondrion transport along microtubule GO:0047497 3 0.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.019
cellular ion homeostasis GO:0006873 165 0.019
salivary gland development GO:0007431 37 0.019
apical constriction GO:0003383 4 0.019
neurotransmitter transport GO:0006836 76 0.019
synapse organization GO:0050808 125 0.018
myosin filament organization GO:0031033 3 0.018
establishment of organelle localization GO:0051656 122 0.018
transmission of nerve impulse GO:0019226 76 0.018
post embryonic hemopoiesis GO:0035166 4 0.018
negative regulation of cell cycle process GO:0010948 69 0.018
oocyte differentiation GO:0009994 35 0.018
regulation of myotube differentiation GO:0010830 62 0.018
positive regulation of protein transport GO:0051222 93 0.018
response to organonitrogen compound GO:0010243 246 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
regulation of system process GO:0044057 200 0.018
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.018
Mouse
regulation of gtp catabolic process GO:0033124 113 0.018
regulation of map kinase activity GO:0043405 120 0.018
oocyte axis specification GO:0007309 2 0.018
actin filament polymerization GO:0030041 44 0.018
negative regulation of wnt signaling pathway GO:0030178 73 0.018
endothelial cell differentiation GO:0045446 41 0.018
establishment of protein localization to plasma membrane GO:0090002 34 0.018
positive regulation of nucleotide catabolic process GO:0030813 88 0.018
cellular response to inorganic substance GO:0071241 37 0.018
positive regulation of cell cycle GO:0045787 92 0.018
peptidyl serine phosphorylation GO:0018105 74 0.018
ribonucleoside monophosphate catabolic process GO:0009158 57 0.017
Mouse
liver development GO:0001889 66 0.017
sensory perception of chemical stimulus GO:0007606 51 0.017
cardiac cell development GO:0055006 41 0.017
metanephric glomerular basement membrane development GO:0072274 1 0.017
negative regulation of cell fate specification GO:0009996 4 0.017
ossification GO:0001503 216 0.017

Plec disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.664
Human
disease of anatomical entity DOID:7 0 0.664
Human
musculoskeletal system disease DOID:17 0 0.664
Human
muscle tissue disease DOID:66 0 0.617
Human
neuromuscular disease DOID:440 0 0.547
charcot marie tooth disease DOID:10595 0 0.547
nervous system disease DOID:863 0 0.547
neuropathy DOID:870 0 0.547
myopathy DOID:423 0 0.514
Human
heart disease DOID:114 0 0.240
cardiomyopathy DOID:0050700 0 0.240
intrinsic cardiomyopathy DOID:0060036 0 0.240
cardiovascular system disease DOID:1287 0 0.240
charcot marie tooth disease type 2 DOID:0050539 0 0.083
muscular dystrophy DOID:9884 0 0.064
Human
sensory system disease DOID:0050155 0 0.061
dilated cardiomyopathy DOID:12930 0 0.041
congenital muscular dystrophy DOID:0050557 0 0.031