Mus musculus

0 known processes

Sh3bgrl

SH3-binding domain glutamic acid-rich protein like

(Aliases: 1190008F14Rik)

Sh3bgrl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of gtpase activity GO:0043547 85 0.632
organophosphate catabolic process GO:0046434 232 0.581
aromatic compound catabolic process GO:0019439 286 0.367
nucleotide catabolic process GO:0009166 217 0.355
regulation of gtp catabolic process GO:0033124 113 0.320
gtp metabolic process GO:0046039 144 0.300
positive regulation of nucleotide metabolic process GO:0045981 114 0.280
ribonucleotide catabolic process GO:0009261 208 0.238
ribose phosphate metabolic process GO:0019693 291 0.227
glycosyl compound metabolic process GO:1901657 246 0.213
ribonucleoside triphosphate catabolic process GO:0009203 199 0.207
guanosine containing compound metabolic process GO:1901068 144 0.205
nucleoside catabolic process GO:0009164 206 0.205
positive regulation of gtp catabolic process GO:0033126 85 0.195
regulation of nucleotide catabolic process GO:0030811 122 0.177
purine nucleoside triphosphate catabolic process GO:0009146 203 0.174
positive regulation of nucleotide catabolic process GO:0030813 88 0.166
establishment of organelle localization GO:0051656 122 0.165
purine nucleoside metabolic process GO:0042278 241 0.157
purine ribonucleoside metabolic process GO:0046128 241 0.156
small gtpase mediated signal transduction GO:0007264 97 0.154
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.148
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.147
organelle localization GO:0051640 179 0.145
membrane fusion GO:0061025 38 0.142
nucleoside phosphate metabolic process GO:0006753 338 0.138
dna metabolic process GO:0006259 303 0.136
leukocyte differentiation GO:0002521 342 0.130
nucleoside triphosphate metabolic process GO:0009141 230 0.128
regulation of purine nucleotide catabolic process GO:0033121 122 0.126
regulation of cellular catabolic process GO:0031329 242 0.124
nucleobase containing small molecule metabolic process GO:0055086 352 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.119
carbohydrate derivative catabolic process GO:1901136 231 0.118
purine ribonucleotide catabolic process GO:0009154 208 0.118
ribonucleoside metabolic process GO:0009119 245 0.115
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.114
regulation of nucleotide metabolic process GO:0006140 169 0.109
regulation of membrane potential GO:0042391 192 0.103
gtp catabolic process GO:0006184 143 0.102
neuron apoptotic process GO:0051402 142 0.096
regulation of neuron differentiation GO:0045664 281 0.091
retina development in camera type eye GO:0060041 119 0.090
heterocycle catabolic process GO:0046700 280 0.087
regulation of purine nucleotide metabolic process GO:1900542 169 0.087
regulation of protein localization GO:0032880 231 0.085
nucleoside metabolic process GO:0009116 246 0.084
ribonucleoside triphosphate metabolic process GO:0009199 220 0.083
regulation of nucleoside metabolic process GO:0009118 130 0.080
regulation of neuron death GO:1901214 134 0.080
stem cell development GO:0048864 219 0.077
cellular nitrogen compound catabolic process GO:0044270 280 0.076
ras protein signal transduction GO:0007265 77 0.076
organic cyclic compound catabolic process GO:1901361 295 0.076
skeletal system morphogenesis GO:0048705 203 0.074
nucleoside phosphate catabolic process GO:1901292 222 0.073
endothelial cell development GO:0001885 20 0.073
positive regulation of ras gtpase activity GO:0032320 65 0.072
positive regulation of protein phosphorylation GO:0001934 242 0.072
positive regulation of protein modification process GO:0031401 299 0.071
camera type eye development GO:0043010 266 0.070
guanosine containing compound catabolic process GO:1901069 144 0.068
positive regulation of hair follicle cell proliferation GO:0071338 1 0.068
ear development GO:0043583 200 0.068
chromosome segregation GO:0007059 48 0.067
purine ribonucleoside catabolic process GO:0046130 205 0.063
purine containing compound catabolic process GO:0072523 213 0.063
positive regulation of metalloenzyme activity GO:0048554 3 0.061
oocyte construction GO:0007308 2 0.061
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.060
regulation of protein kinase activity GO:0045859 232 0.060
glycosyl compound catabolic process GO:1901658 206 0.059
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.059
positive regulation of nucleoside metabolic process GO:0045979 91 0.059
positive regulation of neuron projection development GO:0010976 79 0.058
microtubule based process GO:0007017 236 0.058
dermatan sulfate proteoglycan metabolic process GO:0050655 1 0.058
g protein coupled receptor signaling pathway GO:0007186 243 0.057
establishment of vesicle localization GO:0051650 81 0.057
cell division GO:0051301 120 0.056
purine nucleoside catabolic process GO:0006152 205 0.055
regulation of neuron projection development GO:0010975 169 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
regulation of neuron apoptotic process GO:0043523 122 0.054
skin development GO:0043588 220 0.053
blood vessel morphogenesis GO:0048514 285 0.053
purine nucleotide metabolic process GO:0006163 302 0.052
regulation of cytoskeleton organization GO:0051493 122 0.052
skeletal system development GO:0001501 356 0.051
purine containing compound metabolic process GO:0072521 311 0.051
cell substrate adhesion GO:0031589 130 0.050
chemotaxis GO:0006935 247 0.050
positive regulation of interleukin 8 secretion GO:2000484 1 0.050
positive regulation of apoptotic process GO:0043065 217 0.049
actin cytoskeleton organization GO:0030036 220 0.049
regulation of multi organism process GO:0043900 111 0.047
cellular response to growth factor stimulus GO:0071363 197 0.047
purine nucleotide catabolic process GO:0006195 211 0.045
cellular protein complex assembly GO:0043623 116 0.045
pigmentation GO:0043473 71 0.043
regulation of stress activated mapk cascade GO:0032872 69 0.043
sensory organ morphogenesis GO:0090596 242 0.042
action potential GO:0001508 78 0.041
epidermis development GO:0008544 187 0.040
positive regulation of rap gtpase activity GO:0032854 3 0.040
sensory perception of taste GO:0050909 18 0.040
regulation of kinase activity GO:0043549 249 0.039
positive regulation of cell death GO:0010942 224 0.039
response to endoplasmic reticulum stress GO:0034976 53 0.039
regionalization GO:0003002 337 0.039
asymmetric stem cell division GO:0098722 3 0.038
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.038
regulation of defense response GO:0031347 233 0.037
nucleoside triphosphate catabolic process GO:0009143 205 0.037
positive regulation of cell development GO:0010720 237 0.037
peptidyl amino acid modification GO:0018193 336 0.037
organic hydroxy compound metabolic process GO:1901615 203 0.036
regulation of intracellular protein transport GO:0033157 82 0.036
rap protein signal transduction GO:0032486 3 0.036
positive regulation of mapk cascade GO:0043410 170 0.036
cellular amino acid metabolic process GO:0006520 103 0.035
peptidyl tyrosine modification GO:0018212 145 0.035
positive regulation of programmed cell death GO:0043068 218 0.035
glycerolipid metabolic process GO:0046486 122 0.035
regulation of engulfment of apoptotic cell GO:1901074 2 0.035
retrograde transport endosome to golgi GO:0042147 2 0.034
cellular lipid metabolic process GO:0044255 323 0.034
regulation of organelle organization GO:0033043 289 0.033
regulation of protein stability GO:0031647 52 0.033
regulation of vesicle mediated transport GO:0060627 139 0.033
positive regulation of cell projection organization GO:0031346 95 0.033
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.033
embryonic epithelial tube formation GO:0001838 130 0.033
establishment of spindle localization GO:0051293 19 0.033
positive regulation of transferase activity GO:0051347 167 0.032
endomembrane system organization GO:0010256 147 0.032
establishment or maintenance of cell polarity GO:0007163 86 0.031
regulation of transferase activity GO:0051338 263 0.031
nucleotide metabolic process GO:0009117 332 0.031
cellularization GO:0007349 1 0.031
negative regulation of neuron apoptotic process GO:0043524 92 0.031
embryonic organ morphogenesis GO:0048562 276 0.030
meiotic nuclear division GO:0007126 115 0.030
regulation of cellular response to stress GO:0080135 159 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
retina morphogenesis in camera type eye GO:0060042 45 0.030
regulation of mapk cascade GO:0043408 248 0.030
positive regulation of hydrolase activity GO:0051345 148 0.029
regulation of cell substrate adhesion GO:0010810 73 0.029
negative regulation of secretion by cell GO:1903531 54 0.029
cellular chemical homeostasis GO:0055082 215 0.029
negative regulation of cell proliferation GO:0008285 296 0.028
negative regulation of secretion GO:0051048 61 0.028
positive regulation of jnk cascade GO:0046330 46 0.028
vacuole organization GO:0007033 38 0.028
spindle assembly involved in meiosis GO:0090306 4 0.028
negative regulation of neuron death GO:1901215 98 0.028
cytoplasmic transport GO:0016482 234 0.028
positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902237 3 0.027
l amino acid transport GO:0015807 32 0.027
lymphocyte differentiation GO:0030098 242 0.026
regulation of cell adhesion GO:0030155 154 0.026
establishment of planar polarity GO:0001736 28 0.026
neural tube development GO:0021915 160 0.026
regulation of intracellular transport GO:0032386 159 0.026
neuron death GO:0070997 154 0.026
calcium ion dependent exocytosis GO:0017156 35 0.026
cell type specific apoptotic process GO:0097285 268 0.026
multi multicellular organism process GO:0044706 109 0.025
cell cell junction organization GO:0045216 72 0.025
spindle localization GO:0051653 22 0.025
positive regulation of defense response GO:0031349 124 0.024
metaphase plate congression GO:0051310 2 0.024
mitotic cytokinesis GO:0000281 4 0.024
small molecule catabolic process GO:0044282 71 0.024
positive regulation of neuron differentiation GO:0045666 141 0.024
nitrogen compound transport GO:0071705 271 0.024
blood circulation GO:0008015 195 0.024
positive regulation of protein kinase activity GO:0045860 144 0.024
regulation of cell projection organization GO:0031344 206 0.023
purine ribonucleotide metabolic process GO:0009150 290 0.023
regulation of cell shape GO:0008360 39 0.023
sensory perception GO:0007600 245 0.023
regulation of ion transport GO:0043269 215 0.023
epithelial cell development GO:0002064 159 0.023
cell adhesion GO:0007155 329 0.023
vesicle fusion GO:0006906 16 0.023
regulation of lymphocyte activation GO:0051249 240 0.023
regulation of response to wounding GO:1903034 189 0.022
positive regulation of apoptotic signaling pathway GO:2001235 95 0.022
heart contraction GO:0060047 93 0.022
carbohydrate metabolic process GO:0005975 230 0.022
dna replication GO:0006260 52 0.022
t cell activation GO:0042110 289 0.022
regulation of cellular component size GO:0032535 121 0.022
production of molecular mediator of immune response GO:0002440 103 0.022
positive regulation of nervous system development GO:0051962 221 0.022
regulation of protein transport GO:0051223 163 0.022
spermatid differentiation GO:0048515 115 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
forebrain development GO:0030900 302 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
stress activated protein kinase signaling cascade GO:0031098 81 0.021
peptidyl tyrosine phosphorylation GO:0018108 143 0.021
mapk cascade GO:0000165 281 0.021
angiogenesis GO:0001525 201 0.021
regulation of actin filament based process GO:0032970 99 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
synaptic vesicle localization GO:0097479 59 0.021
protein localization to plasma membrane GO:0072659 57 0.020
neural retina development GO:0003407 41 0.020
cell activation involved in immune response GO:0002263 126 0.020
positive regulation of long term neuronal synaptic plasticity GO:0048170 3 0.020
actin filament organization GO:0007015 113 0.020
neurotransmitter transport GO:0006836 76 0.020
regulation of secretion GO:0051046 274 0.020
tube formation GO:0035148 140 0.020
axon ensheathment GO:0008366 76 0.020
negative regulation of t cell activation GO:0050868 65 0.019
neural tube formation GO:0001841 108 0.019
regulation of establishment of protein localization GO:0070201 181 0.019
multicellular organismal signaling GO:0035637 91 0.019
fatty acid metabolic process GO:0006631 121 0.019
cell junction organization GO:0034330 77 0.019
auditory receptor cell differentiation GO:0042491 37 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
regulation of calcium ion dependent exocytosis GO:0017158 16 0.018
generation of precursor metabolites and energy GO:0006091 103 0.018
regulation of hydrolase activity GO:0051336 246 0.018
positive regulation of cellular amine metabolic process GO:0033240 5 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
cell cell adhesion GO:0098609 41 0.018
establishment of endothelial blood brain barrier GO:0014045 3 0.018
regulation of cell growth GO:0001558 91 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.018
small molecule biosynthetic process GO:0044283 132 0.017
regulation of establishment of planar polarity GO:0090175 28 0.017
cellular homeostasis GO:0019725 240 0.017
establishment of endothelial barrier GO:0061028 5 0.017
proximal convoluted tubule development GO:0072019 1 0.017
bone development GO:0060348 120 0.017
energy derivation by oxidation of organic compounds GO:0015980 77 0.017
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.017
nuclear division GO:0000280 158 0.017
transmission of nerve impulse GO:0019226 76 0.017
mitotic cell cycle GO:0000278 195 0.017
positive regulation of protein export from nucleus GO:0046827 4 0.016
visual perception GO:0007601 52 0.016
stress activated mapk cascade GO:0051403 80 0.016
morphogenesis of embryonic epithelium GO:0016331 159 0.016
morphogenesis of a polarized epithelium GO:0001738 37 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
nucleus localization GO:0051647 20 0.016
negative regulation of exocytosis GO:0045920 12 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
interleukin 4 production GO:0032633 24 0.016
regulation of t cell proliferation GO:0042129 92 0.016
somatic cell dna recombination GO:0016444 51 0.016
branching morphogenesis of an epithelial tube GO:0048754 159 0.016
cardiac muscle hypertrophy GO:0003300 23 0.016
regulation of glycogen catabolic process GO:0005981 2 0.016
central nervous system neuron differentiation GO:0021953 162 0.016
negative regulation of ryanodine sensitive calcium release channel activity GO:0060315 1 0.016
hair cell differentiation GO:0035315 40 0.016
t cell differentiation in thymus GO:0033077 77 0.016
organelle fusion GO:0048284 28 0.015
regulation of interleukin 8 secretion GO:2000482 2 0.015
positive regulation of receptor biosynthetic process GO:0010870 1 0.015
establishment of tissue polarity GO:0007164 28 0.015
establishment of spindle orientation GO:0051294 15 0.015
regulation of protein depolymerization GO:1901879 26 0.015
regulation of leukocyte differentiation GO:1902105 159 0.015
regulation of actin cytoskeleton organization GO:0032956 84 0.015
rna catabolic process GO:0006401 29 0.015
meiotic cell cycle GO:0051321 122 0.015
immunoglobulin production GO:0002377 73 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
positive regulation of kinase activity GO:0033674 155 0.015
response to organonitrogen compound GO:0010243 246 0.015
toxin transport GO:1901998 38 0.015
rab protein signal transduction GO:0032482 1 0.015
hindbrain morphogenesis GO:0021575 46 0.014
positive regulation of protein autophosphorylation GO:0031954 4 0.014
segmentation GO:0035282 93 0.014
regulation of protein serine threonine kinase activity GO:0071900 157 0.014
regulation of anatomical structure size GO:0090066 178 0.014
developmental maturation GO:0021700 193 0.014
positive regulation of cell adhesion GO:0045785 80 0.014
asymmetric neuroblast division GO:0055059 1 0.014
axonogenesis GO:0007409 274 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
protein localization to membrane GO:0072657 108 0.014
cell fate commitment GO:0045165 210 0.014
actin filament depolymerization GO:0030042 15 0.014
connective tissue development GO:0061448 179 0.014
positive regulation of t cell mediated immunity GO:0002711 24 0.014
activation of mapk activity involved in innate immune response GO:0035419 2 0.014
regulation of cell cycle process GO:0010564 160 0.014
wnt signaling pathway GO:0016055 188 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
long chain fatty acid metabolic process GO:0001676 26 0.014
regulation of secretion by cell GO:1903530 249 0.014
apoptotic cell clearance GO:0043277 17 0.014
cytokine production GO:0001816 319 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
rho protein signal transduction GO:0007266 32 0.014
positive regulation of map kinase activity GO:0043406 84 0.013
exocytosis GO:0006887 121 0.013
cerebellar granular layer morphogenesis GO:0021683 10 0.013
heart process GO:0003015 94 0.013
leukocyte migration GO:0050900 124 0.013
neuronal action potential GO:0019228 54 0.013
regulation of wnt signaling pathway GO:0030111 123 0.013
ossification GO:0001503 216 0.013
protein localization to vacuole GO:0072665 4 0.013
plasma membrane organization GO:0007009 90 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
regulation of dna replication GO:0006275 17 0.013
establishment of neuroblast polarity GO:0045200 1 0.013
cytokinetic process GO:0032506 2 0.013
reactive oxygen species metabolic process GO:0072593 84 0.013
positive regulation of growth GO:0045927 104 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
immune effector process GO:0002252 321 0.012
muscle system process GO:0003012 141 0.012
neuroblast differentiation GO:0014016 2 0.012
regulation of cellular response to growth factor stimulus GO:0090287 82 0.012
telencephalon development GO:0021537 186 0.012
protein targeting to vacuole GO:0006623 3 0.012
regulation of jnk cascade GO:0046328 62 0.012
negative regulation of synaptic vesicle exocytosis GO:2000301 3 0.012
spindle assembly involved in female meiosis GO:0007056 3 0.012
fibronectin dependent thymocyte migration GO:0072681 1 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
regulation of vasculature development GO:1901342 88 0.012
carbohydrate homeostasis GO:0033500 128 0.012
amide transport GO:0042886 138 0.012
protein localization to organelle GO:0033365 185 0.012
establishment of mitotic spindle orientation GO:0000132 12 0.012
epithelium migration GO:0090132 63 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
hippocampus development GO:0021766 52 0.012
virion assembly GO:0019068 1 0.011
regulation of jun kinase activity GO:0043506 40 0.011
regulation of exocytosis GO:0017157 61 0.011
sialylation GO:0097503 14 0.011
regulation of cell motility GO:2000145 236 0.011
multicellular organismal reproductive behavior GO:0033057 23 0.011
interleukin 8 secretion GO:0072606 3 0.011
response to lipopolysaccharide GO:0032496 128 0.011
spermatogenesis GO:0007283 284 0.011
positive regulation of innate immune response GO:0045089 80 0.011
positive regulation of cell growth GO:0030307 33 0.011
neural precursor cell proliferation GO:0061351 121 0.011
bone morphogenesis GO:0060349 78 0.011
regulation of inflammatory response GO:0050727 147 0.011
cerebral cortex development GO:0021987 86 0.011
intracellular protein transport GO:0006886 204 0.011
negative regulation of molecular function GO:0044092 258 0.011
mitotic cell cycle process GO:1903047 159 0.011
protein processing GO:0016485 163 0.011
peptide secretion GO:0002790 114 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
dna endoreduplication GO:0042023 4 0.011
positive regulation of cellular component biogenesis GO:0044089 94 0.011
positive regulation of synapse structural plasticity GO:0051835 1 0.010
substantia nigra development GO:0021762 2 0.010
stem cell fate specification GO:0048866 3 0.010
meiotic metaphase plate congression GO:0051311 2 0.010
lymphocyte apoptotic process GO:0070227 54 0.010
ensheathment of neurons GO:0007272 76 0.010
sensory perception of chemical stimulus GO:0007606 51 0.010
hematopoietic progenitor cell differentiation GO:0002244 143 0.010
microtubule based transport GO:0010970 50 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.010

Sh3bgrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.146
retinal degeneration DOID:8466 0 0.146
sensory system disease DOID:0050155 0 0.146
disease of anatomical entity DOID:7 0 0.146
eye and adnexa disease DOID:1492 0 0.146
nervous system disease DOID:863 0 0.146
eye disease DOID:5614 0 0.146
disease of metabolism DOID:0014667 0 0.070
retinitis pigmentosa DOID:10584 0 0.022
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
inherited metabolic disorder DOID:655 0 0.012