Mus musculus

58 known processes

Mtbp

Mdm2, transformed 3T3 cell double minute p53 binding protein

(Aliases: AI429604,MDM2BP)

Mtbp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 158 0.148
dna metabolic process GO:0006259 303 0.140
microtubule based process GO:0007017 236 0.123
organic cyclic compound catabolic process GO:1901361 295 0.117
cellular amino acid metabolic process GO:0006520 103 0.116
mitotic cell cycle process GO:1903047 159 0.106
organelle fission GO:0048285 170 0.105
cellular response to dna damage stimulus GO:0006974 207 0.098
meiotic nuclear division GO:0007126 115 0.093
negative regulation of cellular component organization GO:0051129 194 0.084
dna repair GO:0006281 107 0.084
microtubule cytoskeleton organization GO:0000226 157 0.078
cellular macromolecule catabolic process GO:0044265 206 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.071
recombinational repair GO:0000725 21 0.067
cell cycle checkpoint GO:0000075 47 0.064
cellular ketone metabolic process GO:0042180 84 0.057
regulation of cellular amine metabolic process GO:0033238 20 0.056
organonitrogen compound catabolic process GO:1901565 264 0.056
nitrogen compound transport GO:0071705 271 0.055
dna recombination GO:0006310 92 0.055
double strand break repair via homologous recombination GO:0000724 21 0.051
cellular amine metabolic process GO:0044106 44 0.051
mitotic cell cycle GO:0000278 195 0.051
amine metabolic process GO:0009308 45 0.050
double strand break repair GO:0006302 48 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.048
organophosphate catabolic process GO:0046434 232 0.047
cytoplasmic transport GO:0016482 234 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
glycosyl compound metabolic process GO:1901657 246 0.045
nucleoside triphosphate metabolic process GO:0009141 230 0.044
regulation of cell cycle GO:0051726 281 0.044
purine nucleotide catabolic process GO:0006195 211 0.043
meiotic cell cycle GO:0051321 122 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.043
chromosome segregation GO:0007059 48 0.042
response to radiation GO:0009314 165 0.042
nuclear transport GO:0051169 139 0.040
nucleotide metabolic process GO:0009117 332 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.039
chromatin organization GO:0006325 206 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.037
nucleocytoplasmic transport GO:0006913 139 0.037
purine nucleoside triphosphate metabolic process GO:0009144 226 0.037
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
peptidyl amino acid modification GO:0018193 336 0.036
double strand break repair via nonhomologous end joining GO:0006303 10 0.035
glycosyl compound catabolic process GO:1901658 206 0.035
regulation of cell cycle process GO:0010564 160 0.034
carbohydrate derivative catabolic process GO:1901136 231 0.034
spermatid development GO:0007286 108 0.034
histone modification GO:0016570 159 0.034
male gamete generation GO:0048232 285 0.033
positive regulation of cellular amine metabolic process GO:0033240 5 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.031
nucleoside monophosphate metabolic process GO:0009123 85 0.031
nucleoside metabolic process GO:0009116 246 0.030
spermatogenesis GO:0007283 284 0.030
purine nucleoside catabolic process GO:0006152 205 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
synapsis GO:0007129 34 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
purine ribonucleotide metabolic process GO:0009150 290 0.029
regulation of cell cycle g2 m phase transition GO:1902749 10 0.029
regulation of mitotic cell cycle GO:0007346 126 0.029
positive regulation of protein modification process GO:0031401 299 0.028
negative regulation of cell cycle GO:0045786 123 0.028
nucleotide catabolic process GO:0009166 217 0.028
ribonucleoside triphosphate metabolic process GO:0009199 220 0.028
b cell activation GO:0042113 161 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
regulation of membrane potential GO:0042391 192 0.027
negative regulation of protein metabolic process GO:0051248 282 0.027
regulation of microtubule based process GO:0032886 52 0.027
nuclear import GO:0051170 95 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.026
heterocycle catabolic process GO:0046700 280 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
negative regulation of organelle organization GO:0010639 90 0.025
nucleoside triphosphate catabolic process GO:0009143 205 0.025
positive regulation of lymphocyte activation GO:0051251 140 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
aromatic compound catabolic process GO:0019439 286 0.025
protein methylation GO:0006479 81 0.025
chromosome organization involved in meiosis GO:0070192 39 0.024
protein import GO:0017038 101 0.024
purine containing compound catabolic process GO:0072523 213 0.024
regulation of cell cycle phase transition GO:1901987 77 0.024
macromolecule catabolic process GO:0009057 281 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
regulation of centriole replication GO:0046599 1 0.024
purine containing compound metabolic process GO:0072521 311 0.024
apoptotic signaling pathway GO:0097190 306 0.024
chromatin modification GO:0016568 187 0.024
ribonucleotide catabolic process GO:0009261 208 0.023
male meiosis GO:0007140 37 0.023
regulation of hydrolase activity GO:0051336 246 0.023
lipid biosynthetic process GO:0008610 179 0.023
folic acid containing compound metabolic process GO:0006760 3 0.023
meiotic cell cycle process GO:1903046 77 0.023
developmental maturation GO:0021700 193 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
regulation of chromosome organization GO:0033044 83 0.023
dna catabolic process endonucleolytic GO:0000737 15 0.022
regulation of histone modification GO:0031056 56 0.022
nuclear export GO:0051168 34 0.022
leukocyte differentiation GO:0002521 342 0.022
protein modification by small protein conjugation GO:0032446 187 0.022
female meiosis chromosome segregation GO:0016321 1 0.021
maintenance of location GO:0051235 89 0.021
protein targeting GO:0006605 143 0.021
intracellular protein transport GO:0006886 204 0.021
regulation of cell activation GO:0050865 289 0.021
purine nucleoside metabolic process GO:0042278 241 0.021
camera type eye development GO:0043010 266 0.021
ras protein signal transduction GO:0007265 77 0.021
regulation of transferase activity GO:0051338 263 0.021
lymphocyte differentiation GO:0030098 242 0.021
organelle assembly GO:0070925 177 0.020
atp catabolic process GO:0006200 55 0.020
mrna transport GO:0051028 13 0.020
germ cell development GO:0007281 185 0.020
adaptive immune response GO:0002250 155 0.020
positive regulation of cell activation GO:0050867 158 0.020
t cell activation GO:0042110 289 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
cation transport GO:0006812 399 0.020
response to light stimulus GO:0009416 135 0.019
pore complex assembly GO:0046931 3 0.019
nucleoside catabolic process GO:0009164 206 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
protein localization to nucleus GO:0034504 121 0.019
single organism nuclear import GO:1902593 95 0.019
covalent chromatin modification GO:0016569 163 0.019
male meiosis i GO:0007141 16 0.019
membrane organization GO:0061024 245 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
multicellular organismal signaling GO:0035637 91 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
protein modification by small protein conjugation or removal GO:0070647 207 0.019
positive regulation of nervous system development GO:0051962 221 0.019
protein maturation GO:0051604 176 0.018
leukocyte mediated immunity GO:0002443 174 0.018
regulation of lymphocyte activation GO:0051249 240 0.018
negative regulation of dna replication GO:0008156 4 0.018
anion transport GO:0006820 177 0.018
gland development GO:0048732 330 0.018
organelle localization GO:0051640 179 0.018
methylation GO:0032259 134 0.018
establishment or maintenance of cell polarity GO:0007163 86 0.018
response to organonitrogen compound GO:0010243 246 0.018
purine ribonucleoside metabolic process GO:0046128 241 0.017
fertilization GO:0009566 127 0.017
histone lysine methylation GO:0034968 50 0.017
nucleus organization GO:0006997 45 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
cell activation involved in immune response GO:0002263 126 0.017
protein import into nucleus GO:0006606 95 0.017
regulation of kinase activity GO:0043549 249 0.017
lymphocyte mediated immunity GO:0002449 139 0.017
meiosis i GO:0007127 60 0.017
atp metabolic process GO:0046034 75 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
skeletal system development GO:0001501 356 0.017
regulation of secretion by cell GO:1903530 249 0.017
protein catabolic process GO:0030163 221 0.017
tube formation GO:0035148 140 0.017
regulation of cellular response to stress GO:0080135 159 0.017
mitotic nuclear division GO:0007067 48 0.017
intra s dna damage checkpoint GO:0031573 4 0.017
action potential GO:0001508 78 0.017
anatomical structure homeostasis GO:0060249 145 0.017
ion transmembrane transport GO:0034220 361 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.016
regulation of protein localization GO:0032880 231 0.016
immune effector process GO:0002252 321 0.016
establishment of organelle localization GO:0051656 122 0.016
rna localization GO:0006403 23 0.016
mapk cascade GO:0000165 281 0.016
nucleobase containing compound transport GO:0015931 27 0.016
regulation of organelle organization GO:0033043 289 0.016
peptidyl serine modification GO:0018209 83 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.016
microtubule organizing center organization GO:0031023 28 0.016
macromolecule methylation GO:0043414 120 0.016
protein localization to organelle GO:0033365 185 0.015
regulation of t cell activation GO:0050863 170 0.015
development of primary sexual characteristics GO:0045137 143 0.015
transmembrane transport GO:0055085 412 0.015
response to uv GO:0009411 44 0.015
smoothened signaling pathway GO:0007224 105 0.015
antimicrobial peptide production GO:0002775 2 0.015
retina development in camera type eye GO:0060041 119 0.015
histone threonine phosphorylation GO:0035405 1 0.015
regulation of nuclear division GO:0051783 56 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
peptidyl lysine modification GO:0018205 77 0.015
regulation of secretion GO:0051046 274 0.014
endomembrane system organization GO:0010256 147 0.014
actin filament based movement GO:0030048 23 0.014
protein alkylation GO:0008213 81 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
inflammatory response GO:0006954 244 0.014
dna integrity checkpoint GO:0031570 28 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
protein ubiquitination GO:0016567 171 0.014
regulation of protein maturation GO:1903317 96 0.014
sister chromatid segregation GO:0000819 20 0.014
cofactor metabolic process GO:0051186 80 0.014
dna catabolic process GO:0006308 19 0.014
negative regulation of cell cycle process GO:0010948 69 0.014
spermatid differentiation GO:0048515 115 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
lymphocyte activation involved in immune response GO:0002285 93 0.014
negative regulation of dna recombination GO:0045910 13 0.014
sensory organ morphogenesis GO:0090596 242 0.013
cellular response to cytokine stimulus GO:0071345 189 0.013
regulation of neuron differentiation GO:0045664 281 0.013
cell growth GO:0016049 130 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
centrosome cycle GO:0007098 23 0.013
intracellular mrna localization GO:0008298 4 0.013
leukocyte proliferation GO:0070661 172 0.013
regulation of intracellular transport GO:0032386 159 0.013
monocarboxylic acid metabolic process GO:0032787 191 0.013
heterochromatin organization GO:0070828 4 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
positive regulation of cellular component biogenesis GO:0044089 94 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
lymphocyte proliferation GO:0046651 164 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
establishment of rna localization GO:0051236 18 0.013
centriole assembly GO:0098534 6 0.013
homeostasis of number of cells GO:0048872 210 0.013
organonitrogen compound biosynthetic process GO:1901566 192 0.013
regulation of leukocyte proliferation GO:0070663 121 0.013
cellular response to lipid GO:0071396 145 0.013
muscle cell differentiation GO:0042692 261 0.012
cell maturation GO:0048469 127 0.012
coenzyme metabolic process GO:0006732 52 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
regulation of mapk cascade GO:0043408 248 0.012
dna damage checkpoint GO:0000077 26 0.012
blastocyst development GO:0001824 80 0.012
attachment of spindle microtubules to kinetochore GO:0008608 4 0.012
blood vessel morphogenesis GO:0048514 285 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
negative regulation of protein processing GO:0010955 79 0.012
epithelial tube formation GO:0072175 130 0.012
neural tube formation GO:0001841 108 0.012
synaptonemal complex organization GO:0070193 15 0.012
cilium assembly GO:0042384 81 0.012
purine ribonucleoside catabolic process GO:0046130 205 0.012
organic anion transport GO:0015711 137 0.012
regulation of cell division GO:0051302 76 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
regulation of microtubule cytoskeleton organization GO:0070507 37 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
alpha amino acid metabolic process GO:1901605 59 0.012
regulation of cell migration GO:0030334 219 0.012
telomere capping GO:0016233 4 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
histone h3 k9 methylation GO:0051567 17 0.012
inorganic ion transmembrane transport GO:0098660 234 0.012
regulation of dna recombination GO:0000018 34 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
cellular protein complex assembly GO:0043623 116 0.011
cytokine production GO:0001816 319 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
regulation of nucleotide metabolic process GO:0006140 169 0.011
regulation of cytoskeleton organization GO:0051493 122 0.011
regulation of protein catabolic process GO:0042176 108 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
sensory perception GO:0007600 245 0.011
regulation of system process GO:0044057 200 0.011
nucleic acid transport GO:0050657 18 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of cell death GO:0010942 224 0.011
oxidation reduction process GO:0055114 342 0.011
response to growth factor GO:0070848 198 0.011
cellular lipid metabolic process GO:0044255 323 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.011
negative regulation of protein modification process GO:0031400 163 0.011
b cell mediated immunity GO:0019724 71 0.011
regulation of histone h3 k36 methylation GO:0000414 1 0.011
dna replication GO:0006260 52 0.011
negative regulation of cell development GO:0010721 169 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
positive regulation of organelle organization GO:0010638 128 0.011
regulation of cytokine production GO:0001817 266 0.011
divalent metal ion transport GO:0070838 172 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
positive regulation of lymphocyte proliferation GO:0050671 70 0.011
protein oligomerization GO:0051259 67 0.011
cation transmembrane transport GO:0098655 266 0.011
tube closure GO:0060606 91 0.011
nucleoside monophosphate catabolic process GO:0009125 59 0.011
b cell differentiation GO:0030183 78 0.010
lipid localization GO:0010876 126 0.010
regulation of hormone levels GO:0010817 211 0.010
small molecule biosynthetic process GO:0044283 132 0.010
response to lipopolysaccharide GO:0032496 128 0.010
neural tube development GO:0021915 160 0.010
histone methylation GO:0016571 71 0.010
positive regulation of cell development GO:0010720 237 0.010
positive regulation of leukocyte proliferation GO:0070665 73 0.010
rna transport GO:0050658 18 0.010
connective tissue development GO:0061448 179 0.010
regulation of homeostatic process GO:0032844 182 0.010
urogenital system development GO:0001655 261 0.010
response to inorganic substance GO:0010035 96 0.010
compound eye development GO:0048749 1 0.010
regulation of establishment of protein localization GO:0070201 181 0.010
regulation of cell projection organization GO:0031344 206 0.010
response to organic cyclic compound GO:0014070 198 0.010
regulation of chromatin modification GO:1903308 57 0.010

Mtbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.091
disease of cellular proliferation DOID:14566 0 0.091
immune system disease DOID:2914 0 0.044
disease of anatomical entity DOID:7 0 0.044
hematopoietic system disease DOID:74 0 0.044
nervous system disease DOID:863 0 0.027
organ system cancer DOID:0050686 0 0.015
retinal disease DOID:5679 0 0.014
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
retinal degeneration DOID:8466 0 0.013
aplastic anemia DOID:12449 0 0.013
bone marrow disease DOID:4961 0 0.013
anemia DOID:2355 0 0.013
physical disorder DOID:0080015 0 0.013
immune system cancer DOID:0060083 0 0.012
hematologic cancer DOID:2531 0 0.012
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010