Mus musculus

220 known processes

Plxnb1

plexin B1

(Aliases: mKIAA0407,AU042020,2900002G15Rik)

Plxnb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rho protein signal transduction GO:0007266 32 0.947
regulation of ras gtpase activity GO:0032318 88 0.909
positive regulation of ras gtpase activity GO:0032320 65 0.880
regulation of gtp catabolic process GO:0033124 113 0.873
regulation of rho gtpase activity GO:0032319 58 0.862
gtp catabolic process GO:0006184 143 0.850
guanosine containing compound catabolic process GO:1901069 144 0.841
positive regulation of gtp catabolic process GO:0033126 85 0.827
guanosine containing compound metabolic process GO:1901068 144 0.695
positive regulation of nucleotide catabolic process GO:0030813 88 0.690
nucleotide catabolic process GO:0009166 217 0.665
regulation of nucleoside metabolic process GO:0009118 130 0.635
g protein coupled receptor signaling pathway GO:0007186 243 0.628
regulation of purine nucleotide catabolic process GO:0033121 122 0.618
small gtpase mediated signal transduction GO:0007264 97 0.617
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.615
positive regulation of cellular catabolic process GO:0031331 148 0.599
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.587
nucleoside metabolic process GO:0009116 246 0.554
purine nucleoside triphosphate metabolic process GO:0009144 226 0.527
purine containing compound catabolic process GO:0072523 213 0.522
regulation of neuron projection development GO:0010975 169 0.511
regulation of nucleotide metabolic process GO:0006140 169 0.509
ribonucleoside triphosphate metabolic process GO:0009199 220 0.506
regulation of ras protein signal transduction GO:0046578 114 0.500
gtp metabolic process GO:0046039 144 0.495
heterocycle catabolic process GO:0046700 280 0.492
purine nucleoside metabolic process GO:0042278 241 0.481
nucleoside triphosphate catabolic process GO:0009143 205 0.477
positive regulation of nucleotide metabolic process GO:0045981 114 0.474
purine nucleoside triphosphate catabolic process GO:0009146 203 0.471
ribonucleoside triphosphate catabolic process GO:0009203 199 0.462
regulation of nucleotide catabolic process GO:0030811 122 0.461
glycosyl compound metabolic process GO:1901657 246 0.461
purine containing compound metabolic process GO:0072521 311 0.450
regulation of rho protein signal transduction GO:0035023 71 0.449
cellularization GO:0007349 1 0.415
purine ribonucleoside catabolic process GO:0046130 205 0.406
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.400
glycosyl compound catabolic process GO:1901658 206 0.397
regulation of neuron differentiation GO:0045664 281 0.395
nucleoside catabolic process GO:0009164 206 0.390
purine nucleotide catabolic process GO:0006195 211 0.363
organic cyclic compound catabolic process GO:1901361 295 0.362
ribonucleoside metabolic process GO:0009119 245 0.361
nucleotide metabolic process GO:0009117 332 0.347
cellular nitrogen compound catabolic process GO:0044270 280 0.303
ribonucleotide metabolic process GO:0009259 291 0.299
actin cytoskeleton organization GO:0030036 220 0.278
actin filament based movement GO:0030048 23 0.269
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.268
nucleobase containing small molecule metabolic process GO:0055086 352 0.260
ras protein signal transduction GO:0007265 77 0.253
mechanosensory behavior GO:0007638 6 0.232
regulation of cell projection organization GO:0031344 206 0.172
regulation of cell shape GO:0008360 39 0.171
positive regulation of gtpase activity GO:0043547 85 0.162
actin filament organization GO:0007015 113 0.160
actin cytoskeleton reorganization GO:0031532 21 0.148
actin mediated cell contraction GO:0070252 15 0.135
sensory perception GO:0007600 245 0.131
purine nucleotide metabolic process GO:0006163 302 0.128
epithelial tube morphogenesis GO:0060562 303 0.124
Mouse
positive regulation of nucleoside metabolic process GO:0045979 91 0.117
neural tube development GO:0021915 160 0.115
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.114
ribose phosphate metabolic process GO:0019693 291 0.114
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.109
nucleoside phosphate metabolic process GO:0006753 338 0.108
positive regulation of ras protein signal transduction GO:0046579 13 0.102
positive regulation of rho gtpase activity GO:0032321 41 0.099
neural tube closure GO:0001843 90 0.089
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.088
nucleoside triphosphate metabolic process GO:0009141 230 0.087
postganglionic parasympathetic nervous system development GO:0021784 2 0.087
Mouse
regulation of cytoskeleton organization GO:0051493 122 0.083
Human Mouse
aromatic compound catabolic process GO:0019439 286 0.082
organophosphate catabolic process GO:0046434 232 0.079
purine ribonucleotide metabolic process GO:0009150 290 0.079
positive regulation of rho protein signal transduction GO:0035025 7 0.077
cerebellar granule cell precursor tangential migration GO:0021935 1 0.077
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.071
embryonic epithelial tube formation GO:0001838 130 0.068
Mouse
regulation of cellular catabolic process GO:0031329 242 0.068
positive regulation of cell development GO:0010720 237 0.065
ribonucleotide catabolic process GO:0009261 208 0.064
ribonucleoside catabolic process GO:0042454 206 0.063
carbohydrate derivative catabolic process GO:1901136 231 0.061
regulation of cellular component size GO:0032535 121 0.056
Mouse
neural tube formation GO:0001841 108 0.054
Mouse
regulation of organelle organization GO:0033043 289 0.051
Human Mouse
organonitrogen compound catabolic process GO:1901565 264 0.051
nucleoside phosphate catabolic process GO:1901292 222 0.049
angiogenesis GO:0001525 201 0.044
Mouse
negative regulation of nervous system development GO:0051961 156 0.044
Mouse
neuron projection guidance GO:0097485 141 0.042
Mouse
microtubule based process GO:0007017 236 0.042
regulation of embryonic development GO:0045995 71 0.041
negative regulation of molecular function GO:0044092 258 0.040
positive regulation of organelle organization GO:0010638 128 0.039
Mouse
gland development GO:0048732 330 0.037
Mouse
primary neural tube formation GO:0014020 95 0.037
Mouse
vagus nerve development GO:0021564 3 0.037
Mouse
multi multicellular organism process GO:0044706 109 0.035
cell cell adhesion GO:0098609 41 0.034
negative regulation of cell proliferation GO:0008285 296 0.033
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.033
cell adhesion GO:0007155 329 0.032
Human
regulation of hydrolase activity GO:0051336 246 0.032
purine nucleoside catabolic process GO:0006152 205 0.032
developmental maturation GO:0021700 193 0.032
sensory perception of mechanical stimulus GO:0050954 107 0.032
neuron projection extension GO:1990138 64 0.031
Mouse
positive regulation of cell projection organization GO:0031346 95 0.030
lipid biosynthetic process GO:0008610 179 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
actin filament polymerization GO:0030041 44 0.029
synapse organization GO:0050808 125 0.029
Mouse
regulation of cell activation GO:0050865 289 0.029
positive regulation of neuron differentiation GO:0045666 141 0.028
cellular ketone metabolic process GO:0042180 84 0.026
negative regulation of neuron differentiation GO:0045665 101 0.026
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
regulation of cellular component biogenesis GO:0044087 181 0.026
transmembrane transport GO:0055085 412 0.026
apoptotic signaling pathway GO:0097190 306 0.026
oocyte axis specification GO:0007309 2 0.025
multicellular organismal reproductive behavior GO:0033057 23 0.025
appendage development GO:0048736 166 0.025
Mouse
ameboidal type cell migration GO:0001667 128 0.025
Mouse
immune effector process GO:0002252 321 0.024
microtubule cytoskeleton organization GO:0000226 157 0.024
inflammatory response GO:0006954 244 0.023
regulation of cellular ketone metabolic process GO:0010565 66 0.023
cellular lipid metabolic process GO:0044255 323 0.023
circulatory system process GO:0003013 197 0.023
limb development GO:0060173 166 0.022
Mouse
amine metabolic process GO:0009308 45 0.022
positive regulation of protein phosphorylation GO:0001934 242 0.022
limb morphogenesis GO:0035108 149 0.022
Mouse
cellular amino acid metabolic process GO:0006520 103 0.021
positive regulation of apoptotic process GO:0043065 217 0.021
ossification GO:0001503 216 0.021
respiratory system development GO:0060541 190 0.021
reactive oxygen species metabolic process GO:0072593 84 0.020
neuronal action potential GO:0019228 54 0.020
regulation of protein kinase activity GO:0045859 232 0.020
leukocyte differentiation GO:0002521 342 0.020
regulation of cell migration GO:0030334 219 0.020
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.020
wnt signaling pathway GO:0016055 188 0.020
protein ubiquitination GO:0016567 171 0.020
regulation of neuron death GO:1901214 134 0.020
hindbrain tangential cell migration GO:0021934 2 0.020
Mouse
appendage morphogenesis GO:0035107 149 0.020
Mouse
protein localization to organelle GO:0033365 185 0.020
positive regulation of cell death GO:0010942 224 0.020
cell type specific apoptotic process GO:0097285 268 0.020
cell growth GO:0016049 130 0.020
Mouse
axonogenesis GO:0007409 274 0.019
regulation of axon extension GO:0030516 43 0.019
Mouse
morphogenesis of a branching structure GO:0001763 203 0.019
Mouse
epithelial cell development GO:0002064 159 0.019
mapk cascade GO:0000165 281 0.019
macromolecule catabolic process GO:0009057 281 0.019
neuron death GO:0070997 154 0.019
regulation of mapk cascade GO:0043408 248 0.019
regulation of cellular amino acid metabolic process GO:0006521 5 0.019
neuron apoptotic process GO:0051402 142 0.019
apical constriction GO:0003383 4 0.018
retina development in camera type eye GO:0060041 119 0.018
negative regulation of neuron projection development GO:0010977 50 0.018
Mouse
cytokine production GO:0001816 319 0.018
regulation of cell size GO:0008361 72 0.017
Mouse
camera type eye development GO:0043010 266 0.017
actin polymerization or depolymerization GO:0008154 54 0.017
maintenance of location GO:0051235 89 0.017
positive regulation of transferase activity GO:0051347 167 0.017
dendrite development GO:0016358 115 0.017
anterior commissure morphogenesis GO:0021960 6 0.017
Mouse
negative regulation of immune system process GO:0002683 209 0.017
regulation of vasculature development GO:1901342 88 0.017
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.017
Mouse
response to growth factor GO:0070848 198 0.017
multicellular organism growth GO:0035264 161 0.017
oxidation reduction process GO:0055114 342 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
single organismal cell cell adhesion GO:0016337 131 0.016
regulation of cell growth GO:0001558 91 0.016
Mouse
sensory system development GO:0048880 3 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
respiratory tube development GO:0030323 167 0.016
cellular protein complex assembly GO:0043623 116 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
negative regulation of cell activation GO:0050866 111 0.016
microtubule based movement GO:0007018 84 0.016
regulation of protein localization GO:0032880 231 0.016
regulation of response to wounding GO:1903034 189 0.016
defense response to other organism GO:0098542 197 0.016
branchiomotor neuron axon guidance GO:0021785 7 0.015
Mouse
response to organonitrogen compound GO:0010243 246 0.015
multi organism behavior GO:0051705 62 0.015
lymphocyte differentiation GO:0030098 242 0.015
compound eye development GO:0048749 1 0.015
negative regulation of cellular protein metabolic process GO:0032269 247 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
peripheral nervous system development GO:0007422 53 0.015
Mouse
regulation of protein complex assembly GO:0043254 83 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
cellular macromolecule catabolic process GO:0044265 206 0.014
kidney epithelium development GO:0072073 121 0.014
oocyte construction GO:0007308 2 0.014
renal system development GO:0072001 225 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
bone development GO:0060348 120 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
glycerophospholipid metabolic process GO:0006650 71 0.014
protein maturation GO:0051604 176 0.014
single organism cell adhesion GO:0098602 156 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
regulation of extent of cell growth GO:0061387 52 0.014
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
multicellular organismal signaling GO:0035637 91 0.014
multi organism reproductive behavior GO:0044705 29 0.014
lateral inhibition GO:0046331 1 0.014
cell substrate adhesion GO:0031589 130 0.014
hippocampus development GO:0021766 52 0.014
Mouse
regulation of angiogenesis GO:0045765 81 0.014
Mouse
establishment of organelle localization GO:0051656 122 0.014
organophosphate biosynthetic process GO:0090407 122 0.014
positive regulation of neuron projection development GO:0010976 79 0.014
germ cell development GO:0007281 185 0.014
negative regulation of t cell activation GO:0050868 65 0.014
hindbrain development GO:0030902 128 0.014
Mouse
positive regulation of protein modification process GO:0031401 299 0.014
leukocyte proliferation GO:0070661 172 0.013
regulation of t cell activation GO:0050863 170 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
Mouse
anion transport GO:0006820 177 0.013
synapse assembly GO:0007416 56 0.013
Mouse
t cell differentiation GO:0030217 174 0.013
regulation of multi organism process GO:0043900 111 0.013
action potential GO:0001508 78 0.013
lung development GO:0030324 164 0.013
male gamete generation GO:0048232 285 0.013
negative regulation of cell motility GO:2000146 61 0.013
regulation of cellular response to stress GO:0080135 159 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
negative regulation of osteoblast proliferation GO:0033689 4 0.013
cerebral cortex development GO:0021987 86 0.013
ion transmembrane transport GO:0034220 361 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
spermatogenesis GO:0007283 284 0.013
chromatin organization GO:0006325 206 0.013
limbic system development GO:0021761 72 0.013
Mouse
blood circulation GO:0008015 195 0.013
transmission of nerve impulse GO:0019226 76 0.013
negative chemotaxis GO:0050919 14 0.013
Mouse
positive regulation of rac gtpase activity GO:0032855 14 0.013
endocytosis GO:0006897 168 0.013
organelle assembly GO:0070925 177 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
axon extension involved in axon guidance GO:0048846 14 0.012
Mouse
forebrain neuron development GO:0021884 30 0.012
Mouse
muscle cell differentiation GO:0042692 261 0.012
rhythmic process GO:0048511 174 0.012
carbohydrate metabolic process GO:0005975 230 0.012
regulation of leukocyte proliferation GO:0070663 121 0.012
protein catabolic process GO:0030163 221 0.012
regulation of actin polymerization or depolymerization GO:0008064 45 0.012
regulation of actin filament polymerization GO:0030833 38 0.012
lymphocyte proliferation GO:0046651 164 0.012
muscle tissue development GO:0060537 308 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
regulation of secretion GO:0051046 274 0.012
cognition GO:0050890 149 0.012
lateral line system development GO:0048925 1 0.011
mitotic cell cycle GO:0000278 195 0.011
positive regulation of protein binding GO:0032092 29 0.011
Mouse
regulation of membrane potential GO:0042391 192 0.011
myeloid leukocyte activation GO:0002274 83 0.011
kidney development GO:0001822 213 0.011
neuron neuron synaptic transmission GO:0007270 69 0.011
glossopharyngeal nerve morphogenesis GO:0021615 4 0.011
Mouse
cytoskeleton dependent intracellular transport GO:0030705 50 0.011
response to insulin GO:0032868 100 0.011
cation transmembrane transport GO:0098655 266 0.011
sensory organ morphogenesis GO:0090596 242 0.011
regulation of cellular amine metabolic process GO:0033238 20 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
membrane organization GO:0061024 245 0.011
regulation of endocytosis GO:0030100 69 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
chemotaxis GO:0006935 247 0.011
Mouse
rna interference GO:0016246 2 0.011
urogenital system development GO:0001655 261 0.011
cation transport GO:0006812 399 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
endothelial cell migration GO:0043542 44 0.011
Mouse
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.011
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.011
regulation of cell cycle GO:0051726 281 0.011
anatomical structure arrangement GO:0048532 20 0.011
Mouse
intracellular protein transport GO:0006886 204 0.011
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.010
Mouse
b cell activation GO:0042113 161 0.010
leukocyte migration GO:0050900 124 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
Mouse
phospholipid metabolic process GO:0006644 87 0.010
regulation of cell motility GO:2000145 236 0.010
Mouse
negative regulation of neuron death GO:1901215 98 0.010
striated muscle myosin thick filament assembly GO:0071688 1 0.010
regulation of defense response GO:0031347 233 0.010
lipid localization GO:0010876 126 0.010
response to peptide hormone GO:0043434 127 0.010
mesodermal cell migration GO:0008078 4 0.010
positive regulation of podosome assembly GO:0071803 3 0.010
ensheathment of neurons GO:0007272 76 0.010
cellular response to hormone stimulus GO:0032870 150 0.010
cellular response to dna damage stimulus GO:0006974 207 0.010
negative regulation of growth GO:0045926 99 0.010
Mouse

Plxnb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.346
cancer DOID:162 0 0.320
immune system cancer DOID:0060083 0 0.281
organ system cancer DOID:0050686 0 0.281
myeloid leukemia DOID:8692 0 0.193
hematologic cancer DOID:2531 0 0.193
leukemia DOID:1240 0 0.193
acute myeloid leukemia DOID:9119 0 0.092
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013