Mus musculus

201 known processes

Tal1

T-cell acute lymphocytic leukemia 1

(Aliases: tal-1,Scl,bHLHa17,SCL/tal-1)

Tal1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of erythrocyte differentiation GO:0045646 23 0.994
erythrocyte differentiation GO:0030218 88 0.989
myeloid cell differentiation GO:0030099 233 0.983
histone acetylation GO:0016573 41 0.979
Mouse
cell fate specification GO:0001708 72 0.973
Mouse
covalent chromatin modification GO:0016569 163 0.968
Mouse
negative regulation of myeloid cell differentiation GO:0045638 38 0.933
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.927
Mouse
spinal cord development GO:0021510 81 0.925
gastrulation GO:0007369 116 0.921
cell differentiation in spinal cord GO:0021515 53 0.916
myeloid cell homeostasis GO:0002262 114 0.912
eosinophil differentiation GO:0030222 1 0.898
histone modification GO:0016570 159 0.895
Mouse
internal protein amino acid acetylation GO:0006475 42 0.893
Mouse
aortic valve morphogenesis GO:0003180 4 0.891
Mouse
ventral spinal cord interneuron differentiation GO:0021514 16 0.882
regulation of cellular amino acid metabolic process GO:0006521 5 0.874
regionalization GO:0003002 337 0.865
Mouse
central nervous system neuron differentiation GO:0021953 162 0.831
protein acylation GO:0043543 64 0.824
Mouse
peptidyl lysine modification GO:0018205 77 0.810
Mouse
chromatin modification GO:0016568 187 0.810
Mouse
head morphogenesis GO:0060323 34 0.793
Mouse
sensory organ morphogenesis GO:0090596 242 0.791
Mouse
embryonic placenta development GO:0001892 98 0.779
Mouse
cardiac chamber development GO:0003205 108 0.760
Mouse
cell fate commitment GO:0045165 210 0.733
striated muscle tissue development GO:0014706 293 0.732
Mouse
ventral spinal cord development GO:0021517 48 0.724
cardiac ventricle development GO:0003231 83 0.723
Mouse
somatic stem cell maintenance GO:0035019 47 0.719
digestive tract development GO:0048565 190 0.718
primitive hemopoiesis GO:0060215 7 0.707
spinal cord association neuron differentiation GO:0021527 14 0.702
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.697
heart morphogenesis GO:0003007 178 0.695
Zebrafish Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.694
muscle tissue development GO:0060537 308 0.677
Mouse
epithelial tube formation GO:0072175 130 0.671
Mouse
stem cell differentiation GO:0048863 268 0.669
neural tube closure GO:0001843 90 0.664
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.662
Mouse
regulation of chromatin modification GO:1903308 57 0.643
Mouse
homeostasis of number of cells GO:0048872 210 0.636
amine metabolic process GO:0009308 45 0.635
regulation of histone h3 k4 methylation GO:0051569 12 0.627
wnt signaling pathway GO:0016055 188 0.625
regulation of cell activation GO:0050865 289 0.614
cardiac chamber morphogenesis GO:0003206 93 0.614
Mouse
cardiac septum development GO:0003279 59 0.610
tube formation GO:0035148 140 0.609
Mouse
stem cell maintenance GO:0019827 130 0.609
fat cell differentiation GO:0045444 160 0.607
bmp signaling pathway GO:0030509 93 0.603
Mouse
cell adhesion GO:0007155 329 0.599
megakaryocyte differentiation GO:0030219 26 0.591
response to molecule of bacterial origin GO:0002237 143 0.585
neural tube development GO:0021915 160 0.575
Mouse
gland development GO:0048732 330 0.566
Zebrafish Mouse
regulation of dna binding GO:0051101 39 0.562
Mouse
regulation of homeostatic process GO:0032844 182 0.561
hematopoietic progenitor cell differentiation GO:0002244 143 0.526
regulation of muscle tissue development GO:1901861 97 0.523
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.519
Mouse
regulation of neuron differentiation GO:0045664 281 0.518
Mouse
epidermis development GO:0008544 187 0.511
Mouse
inner ear morphogenesis GO:0042472 101 0.510
Mouse
cytokine production GO:0001816 319 0.502
Mouse
cardiac muscle tissue development GO:0048738 130 0.492
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.485
myeloid leukocyte differentiation GO:0002573 119 0.483
developmental maturation GO:0021700 193 0.478
gonad morphogenesis GO:0035262 1 0.474
peptidyl amino acid modification GO:0018193 336 0.467
Mouse
hindbrain development GO:0030902 128 0.462
Mouse
cellular amino acid metabolic process GO:0006520 103 0.458
cardiac septum morphogenesis GO:0060411 46 0.453
regulation of cellular ketone metabolic process GO:0010565 66 0.447
muscle cell differentiation GO:0042692 261 0.445
regulation of peptidyl lysine acetylation GO:2000756 22 0.441
Mouse
ventricular septum development GO:0003281 42 0.437
chromatin organization GO:0006325 206 0.435
Human Mouse
septum primum development GO:0003284 4 0.434
axon guidance GO:0007411 141 0.431
Mouse
digestive tract morphogenesis GO:0048546 147 0.425
histone methylation GO:0016571 71 0.425
transdifferentiation GO:0060290 1 0.424
Mouse
regulation of stem cell differentiation GO:2000736 50 0.421
neural tube formation GO:0001841 108 0.420
Mouse
regulation of cytokine production GO:0001817 266 0.407
Mouse
organ growth GO:0035265 117 0.404
cellular response to thyroid hormone stimulus GO:0097067 1 0.400
embryonic organ morphogenesis GO:0048562 276 0.398
Mouse
cardiocyte differentiation GO:0035051 87 0.394
Mouse
neuron projection guidance GO:0097485 141 0.391
Mouse
regulation of binding GO:0051098 111 0.390
Mouse
gonad development GO:0008406 141 0.385
t helper 2 cell differentiation GO:0045064 12 0.383
negative regulation of immune system process GO:0002683 209 0.379
Mouse
primary neural tube formation GO:0014020 95 0.379
Mouse
response to lipopolysaccharide GO:0032496 128 0.377
cellular ketone metabolic process GO:0042180 84 0.370
digestive system development GO:0055123 200 0.369
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.359
kidney development GO:0001822 213 0.357
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.356
Mouse
mesenchyme development GO:0060485 152 0.352
Zebrafish Mouse
response to bmp GO:0071772 14 0.351
Mouse
stem cell development GO:0048864 219 0.347
formation of primary germ layer GO:0001704 77 0.347
heart valve development GO:0003170 23 0.344
Mouse
enteroendocrine cell differentiation GO:0035883 16 0.342
Mouse
renal system development GO:0072001 225 0.340
liver development GO:0001889 66 0.339
development of primary sexual characteristics GO:0045137 143 0.333
cellular response to growth factor stimulus GO:0071363 197 0.324
Mouse
regulation of neuron projection development GO:0010975 169 0.322
Mouse
angiogenesis GO:0001525 201 0.321
metencephalon development GO:0022037 89 0.312
Mouse
ear development GO:0043583 200 0.309
Mouse
negative regulation of ossification GO:0030279 49 0.308
Mouse
skin development GO:0043588 220 0.307
Mouse
embryonic epithelial tube formation GO:0001838 130 0.307
Mouse
mast cell differentiation GO:0060374 5 0.305
determination of heart left right asymmetry GO:0061371 48 0.299
Mouse
cell differentiation in hindbrain GO:0021533 24 0.297
body morphogenesis GO:0010171 45 0.296
Mouse
regulation of cardiac muscle tissue development GO:0055024 31 0.296
positive regulation of nervous system development GO:0051962 221 0.296
Mouse
regulation of histone modification GO:0031056 56 0.295
Mouse
dendrite development GO:0016358 115 0.294
Mouse
axonogenesis GO:0007409 274 0.294
Mouse
neuron migration GO:0001764 122 0.293
Mouse
t cell differentiation GO:0030217 174 0.292
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.291
Mouse
wound healing GO:0042060 157 0.290
lymphocyte differentiation GO:0030098 242 0.290
Mouse
gene looping GO:0090202 2 0.289
cardiac atrium development GO:0003230 24 0.286
regulation of cardiac muscle cell proliferation GO:0060043 23 0.278
mitral valve morphogenesis GO:0003183 4 0.276
Mouse
camera type eye development GO:0043010 266 0.275
Mouse
regulation of protein acetylation GO:1901983 22 0.273
Mouse
aortic valve development GO:0003176 5 0.272
Mouse
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.272
positive regulation of protein phosphorylation GO:0001934 242 0.268
cardiac muscle cell differentiation GO:0055007 69 0.267
regulation of organ growth GO:0046620 61 0.261
placenta development GO:0001890 140 0.260
Mouse
positive regulation of cell adhesion GO:0045785 80 0.259
hemangioblast cell differentiation GO:0060217 1 0.257
phenol containing compound biosynthetic process GO:0046189 21 0.255
Mouse
hemostasis GO:0007599 78 0.254
alpha beta t cell activation involved in immune response GO:0002287 31 0.254
cell fate determination GO:0001709 32 0.252
Mouse
atrioventricular valve morphogenesis GO:0003181 13 0.247
Mouse
regulation of histone acetylation GO:0035065 19 0.247
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.243
granulocyte differentiation GO:0030851 17 0.243
Human
positive regulation of homeostatic process GO:0032846 64 0.241
regulation of cardiac muscle tissue growth GO:0055021 26 0.239
tendon formation GO:0035992 4 0.237
Mouse
heart growth GO:0060419 45 0.235
peptidyl lysine acetylation GO:0018394 45 0.234
Mouse
somatic cell dna recombination GO:0016444 51 0.231
erythrocyte maturation GO:0043249 6 0.228
regulation of cell cycle GO:0051726 281 0.221
Human Mouse
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.220
regulation of organ morphogenesis GO:2000027 144 0.218
Mouse
ureteric bud development GO:0001657 94 0.217
regulation of chromosome organization GO:0033044 83 0.217
Human Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.214
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.212
clara cell differentiation GO:0060486 4 0.212
regulation of neuron apoptotic process GO:0043523 122 0.211
pancreatic pp cell fate commitment GO:0003329 2 0.210
Mouse
definitive hemopoiesis GO:0060216 20 0.209
regulation of chromatin organization GO:1902275 57 0.209
Human Mouse
somatic diversification of immune receptors GO:0002200 53 0.209
central nervous system neuron development GO:0021954 67 0.208
Mouse
cardiac atrium morphogenesis GO:0003209 23 0.206
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.205
muscle system process GO:0003012 141 0.205
regulation of protein complex assembly GO:0043254 83 0.205
Human
peptidyl tyrosine phosphorylation GO:0018108 143 0.203
negative regulation of molecular function GO:0044092 258 0.202
Mouse
regulation of ossification GO:0030278 112 0.202
Mouse
coagulation GO:0050817 78 0.199
retina morphogenesis in camera type eye GO:0060042 45 0.198
Mouse
endodermal cell fate determination GO:0007493 2 0.197
negative regulation of binding GO:0051100 39 0.195
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.195
Mouse
mesonephros development GO:0001823 97 0.194
muscle cell development GO:0055001 133 0.194
nephron epithelium development GO:0072009 92 0.192
single organismal cell cell adhesion GO:0016337 131 0.189
multicellular organismal homeostasis GO:0048871 164 0.189
Mouse
lung development GO:0030324 164 0.189
gastrulation with mouth forming second GO:0001702 29 0.189
positive regulation of myeloid cell differentiation GO:0045639 43 0.188
hematopoietic stem cell differentiation GO:0060218 8 0.188
establishment or maintenance of cell polarity GO:0007163 86 0.188
Mouse
response to retinoic acid GO:0032526 56 0.187
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.185
regulation of heart growth GO:0060420 31 0.184
urogenital system development GO:0001655 261 0.183
pancreatic a cell differentiation GO:0003310 7 0.182
Mouse
definitive erythrocyte differentiation GO:0060318 7 0.182
epithelial tube morphogenesis GO:0060562 303 0.182
Mouse
blood coagulation GO:0007596 76 0.181
sympathetic nervous system development GO:0048485 22 0.181
Mouse
negative regulation of leukocyte differentiation GO:1902106 51 0.180
nephric duct formation GO:0072179 4 0.180
cell type specific apoptotic process GO:0097285 268 0.180
Mouse
forebrain neuron fate commitment GO:0021877 13 0.179
atrial septum primum morphogenesis GO:0003289 3 0.179
negative regulation of protein metabolic process GO:0051248 282 0.178
Mouse
platelet formation GO:0030220 12 0.178
endoderm development GO:0007492 45 0.177
histone h3 acetylation GO:0043966 14 0.177
ureteric bud morphogenesis GO:0060675 62 0.176
regulation of t cell activation GO:0050863 170 0.176
t cell activation GO:0042110 289 0.176
muscle adaptation GO:0043500 39 0.175
negative regulation of fat cell differentiation GO:0045599 36 0.175
hepaticobiliary system development GO:0061008 67 0.175
regulation of histone h3 k27 methylation GO:0061085 6 0.174
dna metabolic process GO:0006259 303 0.174
wnt signaling pathway involved in kidney development GO:0061289 2 0.174
connective tissue development GO:0061448 179 0.174
Mouse
histone lysine methylation GO:0034968 50 0.173
cellular amine metabolic process GO:0044106 44 0.169
glial cell differentiation GO:0010001 131 0.168
regulation of cell projection organization GO:0031344 206 0.168
Mouse
neural tube patterning GO:0021532 43 0.167
dna recombination GO:0006310 92 0.165
heart valve formation GO:0003188 10 0.165
Mouse
forebrain development GO:0030900 302 0.164
Mouse
bone mineralization GO:0030282 54 0.164
regulation of neural precursor cell proliferation GO:2000177 70 0.163
ear morphogenesis GO:0042471 118 0.163
Mouse
neuron fate specification GO:0048665 30 0.163
Mouse
positive regulation of striated muscle tissue development GO:0045844 31 0.162
cell maturation GO:0048469 127 0.161
autonomic nervous system development GO:0048483 43 0.161
Mouse
positive regulation of cell development GO:0010720 237 0.160
Mouse
regulation of organelle organization GO:0033043 289 0.159
Human Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.158
Mouse
neuron apoptotic process GO:0051402 142 0.157
single organism cell adhesion GO:0098602 156 0.157
face morphogenesis GO:0060325 29 0.156
Mouse
response to thyroid hormone GO:0097066 2 0.155
regulation of definitive erythrocyte differentiation GO:0010724 3 0.154
negative regulation of cell proliferation GO:0008285 296 0.154
Mouse
internal peptidyl lysine acetylation GO:0018393 42 0.154
Mouse
metanephros development GO:0001656 79 0.154
odontogenesis of dentin containing tooth GO:0042475 66 0.153
Mouse
production of molecular mediator of immune response GO:0002440 103 0.153
anatomical structure homeostasis GO:0060249 145 0.151
Mouse
neuroepithelial cell differentiation GO:0060563 37 0.147
cardiac muscle tissue growth GO:0055017 37 0.147
mitral valve development GO:0003174 4 0.147
Mouse
epithelial cell fate commitment GO:0072148 13 0.146
Mouse
regulation of t cell differentiation GO:0045580 83 0.146
epithelial cell development GO:0002064 159 0.145
Mouse
striated muscle cell development GO:0055002 125 0.144
histone h3 k4 methylation GO:0051568 23 0.144
striated muscle adaptation GO:0014888 26 0.143
appendage morphogenesis GO:0035107 149 0.142
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.141
regulation of myeloid leukocyte differentiation GO:0002761 58 0.141
negative regulation of myeloid leukocyte differentiation GO:0002762 20 0.140
mesoderm development GO:0007498 100 0.140
spinal cord motor neuron differentiation GO:0021522 35 0.139
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.139
negative regulation of cytokine production GO:0001818 84 0.139
Mouse
cardiac right ventricle formation GO:0003219 3 0.139
Mouse
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.139
regulation of anterior head development GO:2000742 2 0.138
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.137
regulation of embryonic development GO:0045995 71 0.137
Mouse
response to fibroblast growth factor GO:0071774 47 0.137
response to transforming growth factor beta GO:0071559 88 0.137
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.137
neuroblast differentiation GO:0014016 2 0.135
alpha beta t cell differentiation GO:0046632 69 0.134
leukocyte differentiation GO:0002521 342 0.134
regulation of cardioblast differentiation GO:0051890 3 0.134
mitotic cell cycle GO:0000278 195 0.134
Human Mouse
striated muscle cell proliferation GO:0014855 39 0.133
stem cell fate specification GO:0048866 3 0.129
immunoglobulin production GO:0002377 73 0.128
t cell differentiation involved in immune response GO:0002292 30 0.127
negative regulation of cell development GO:0010721 169 0.127
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.126
Mouse
immune effector process GO:0002252 321 0.126
endodermal cell fate commitment GO:0001711 12 0.124
negative regulation of chromatin modification GO:1903309 19 0.124
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.122
Mouse
regulation of megakaryocyte differentiation GO:0045652 7 0.122
chemotaxis GO:0006935 247 0.121
Mouse
tissue homeostasis GO:0001894 115 0.120
Mouse
embryonic heart tube development GO:0035050 65 0.118
Zebrafish Mouse
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.118
positive regulation of lymphocyte activation GO:0051251 140 0.117
t helper cell differentiation GO:0042093 28 0.117
macrophage differentiation GO:0030225 20 0.117
chondrocyte differentiation GO:0002062 72 0.116
Mouse
atrial septum morphogenesis GO:0060413 11 0.116
embryonic digestive tract development GO:0048566 27 0.115
embryonic digit morphogenesis GO:0042733 56 0.114
Mouse
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.114
Mouse
thymus development GO:0048538 41 0.114
Mouse
glandular epithelial cell differentiation GO:0002067 38 0.114
Mouse
regulation of fat cell differentiation GO:0045598 81 0.114
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.113
anatomical structure maturation GO:0071695 49 0.113
diencephalon development GO:0021536 63 0.112
Mouse
biomineral tissue development GO:0031214 64 0.112
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.112
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.112
mesonephric epithelium development GO:0072163 94 0.111
t cell differentiation in thymus GO:0033077 77 0.110
regulation of angiogenesis GO:0045765 81 0.110
heart valve morphogenesis GO:0003179 21 0.109
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.109
endocardial cushion development GO:0003197 26 0.109
Mouse
negative regulation of chromosome organization GO:2001251 30 0.108
Mouse
neuron death GO:0070997 154 0.108
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.108
nephron tubule development GO:0072080 84 0.108
forebrain generation of neurons GO:0021872 63 0.108
regulation of auditory receptor cell differentiation GO:0045607 4 0.107
Mouse
renal tubule morphogenesis GO:0061333 72 0.107
embryonic limb morphogenesis GO:0030326 126 0.107
Mouse
lymphocyte activation involved in immune response GO:0002285 93 0.107
tongue development GO:0043586 18 0.106
Mouse
nephron morphogenesis GO:0072028 69 0.106
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.106
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.106
Mouse
regulation of hematopoietic progenitor cell differentiation GO:1901532 18 0.105
lens development in camera type eye GO:0002088 62 0.105
ventricular cardiac muscle tissue development GO:0003229 38 0.105
Mouse
response to oxygen radical GO:0000305 16 0.105
inflammatory response GO:0006954 244 0.105
auditory receptor cell fate determination GO:0042668 3 0.105
Mouse
platelet morphogenesis GO:0036344 13 0.104
multi multicellular organism process GO:0044706 109 0.104
pituitary gland development GO:0021983 38 0.104
cellular homeostasis GO:0019725 240 0.103
protein alkylation GO:0008213 81 0.101
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.101
muscle cell proliferation GO:0033002 52 0.100
regulation of ion transport GO:0043269 215 0.100
Mouse
positive regulation of protein modification process GO:0031401 299 0.100
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.099
Mouse
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.099
Mouse
response to growth factor GO:0070848 198 0.099
Mouse
homotypic cell cell adhesion GO:0034109 28 0.099
positive regulation of megakaryocyte differentiation GO:0045654 4 0.099
spermatogenesis GO:0007283 284 0.098
regulation of wnt signaling pathway GO:0030111 123 0.098
regulation of neuron death GO:1901214 134 0.098
positive regulation of ureteric bud formation GO:0072107 3 0.098
somitogenesis GO:0001756 69 0.098
Mouse
positive regulation of cell death GO:0010942 224 0.097
Mouse
skeletal muscle fiber development GO:0048741 58 0.097
sclerotome development GO:0061056 4 0.096
Mouse
segmentation GO:0035282 93 0.096
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.096
tendon cell differentiation GO:0035990 4 0.095
Mouse
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.095
response to organonitrogen compound GO:0010243 246 0.095
endocrine pancreas development GO:0031018 29 0.094
Mouse
cardiac muscle cell proliferation GO:0060038 31 0.094
nephron development GO:0072006 109 0.094
protein methylation GO:0006479 81 0.093
locomotory behavior GO:0007626 195 0.092
ossification GO:0001503 216 0.092
Mouse
phospholipid metabolic process GO:0006644 87 0.092
embryonic digestive tract morphogenesis GO:0048557 17 0.091
response to estrogen GO:0043627 24 0.090
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.090
Mouse
endoderm formation GO:0001706 20 0.090
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.089
mesonephric tubule development GO:0072164 94 0.089
inorganic ion transmembrane transport GO:0098660 234 0.089
pro t cell differentiation GO:0002572 3 0.088
embryonic heart tube morphogenesis GO:0003143 51 0.088
Mouse
canonical wnt signaling pathway GO:0060070 130 0.087
face development GO:0060324 38 0.087
Mouse
cellular response to gonadotropin stimulus GO:0071371 4 0.087
embryonic appendage morphogenesis GO:0035113 126 0.087
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.086
cellular response to oxidative stress GO:0034599 76 0.086
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.086
Mouse
regulation of histone methylation GO:0031060 30 0.086
mesenchyme morphogenesis GO:0072132 32 0.086
Mouse
negative regulation of macrophage differentiation GO:0045650 4 0.085
negative regulation of apoptotic signaling pathway GO:2001234 104 0.085
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.085
Mouse
renal tubule development GO:0061326 87 0.085
multi organism behavior GO:0051705 62 0.084
Mouse
bone development GO:0060348 120 0.084
Mouse
male sex differentiation GO:0046661 109 0.084
forelimb morphogenesis GO:0035136 40 0.083
Mouse
coronary artery morphogenesis GO:0060982 6 0.083
Mouse
smad protein signal transduction GO:0060395 21 0.083
organ regeneration GO:0031100 2 0.083
positive regulation of t cell differentiation GO:0045582 52 0.082
endodermal cell fate specification GO:0001714 4 0.082
nephron tubule morphogenesis GO:0072078 68 0.082
positive regulation of transcription regulatory region dna binding GO:2000679 1 0.082
mesenchymal cell proliferation GO:0010463 44 0.082
Mouse
regulation of interleukin 2 production GO:0032663 28 0.081
interferon gamma production GO:0032609 67 0.081
regulation of lymphocyte activation GO:0051249 240 0.081
mesonephric tubule morphogenesis GO:0072171 63 0.080
positive regulation of cell activation GO:0050867 158 0.080
astrocyte fate commitment GO:0060018 4 0.080
telencephalon development GO:0021537 186 0.079
Mouse
forebrain neuron differentiation GO:0021879 52 0.078
mesoderm formation GO:0001707 62 0.078
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.078
Mouse
pancreas development GO:0031016 57 0.078
Mouse
atrial septum development GO:0003283 12 0.078
negative regulation of erythrocyte differentiation GO:0045647 5 0.077
epithelial to mesenchymal transition GO:0001837 47 0.077
Mouse
alpha beta t cell activation GO:0046631 91 0.077
regulation of canonical wnt signaling pathway GO:0060828 82 0.077
negative regulation of homeostatic process GO:0032845 71 0.077
epidermal cell fate specification GO:0009957 1 0.076
positive regulation of cardiac muscle tissue development GO:0055025 19 0.076
regulation of chemokine production GO:0032642 30 0.076
regulation of biomineral tissue development GO:0070167 33 0.076
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.075
Mouse
positive regulation of mesonephros development GO:0061213 20 0.075
cytokine secretion GO:0050663 72 0.075
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.075
somatic diversification of immunoglobulins GO:0016445 43 0.075
kidney morphogenesis GO:0060993 83 0.075
regulation of mast cell differentiation GO:0060375 3 0.075
positive regulation of binding GO:0051099 49 0.074
cellular response to dna damage stimulus GO:0006974 207 0.074
cell differentiation involved in kidney development GO:0061005 33 0.074
male gamete generation GO:0048232 285 0.074
catecholamine biosynthetic process GO:0042423 11 0.073
Mouse
regulation of multi organism process GO:0043900 111 0.073
otic vesicle development GO:0071599 14 0.073
killing by host of symbiont cells GO:0051873 11 0.073
notch signaling pathway GO:0007219 71 0.073
Mouse
regulation of cardioblast proliferation GO:0003264 9 0.072
Mouse
regulation of alpha beta t cell differentiation GO:0046637 35 0.072
methylation GO:0032259 134 0.072
limb development GO:0060173 166 0.071
Mouse
limb morphogenesis GO:0035108 149 0.071
Mouse
foregut morphogenesis GO:0007440 12 0.071
norepinephrine biosynthetic process GO:0042421 5 0.071
Mouse
regulation of cell proliferation involved in mesonephros development GO:2000606 1 0.070
nephron tubule epithelial cell differentiation GO:0072160 11 0.070
regulation of leukocyte differentiation GO:1902105 159 0.070
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.070
visceral motor neuron differentiation GO:0021524 3 0.070
cellular response to interleukin 4 GO:0071353 21 0.070
response to acid chemical GO:0001101 111 0.070
cerebellar cortex development GO:0021695 48 0.069
Mouse
protein secretion GO:0009306 111 0.069
glial cell derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation GO:2000701 1 0.069
compound eye development GO:0048749 1 0.069
regulation of engulfment of apoptotic cell GO:1901074 2 0.068
bone morphogenesis GO:0060349 78 0.068
Mouse
embryonic heart tube formation GO:0003144 1 0.067
Mouse
monocyte differentiation GO:0030224 9 0.067
positive regulation of organ growth GO:0046622 29 0.067
neuroblast fate commitment GO:0014017 1 0.066
ras protein signal transduction GO:0007265 77 0.066
positive regulation of cardioblast differentiation GO:0051891 3 0.066
immune response activating signal transduction GO:0002757 116 0.066
appendage development GO:0048736 166 0.065
Mouse
regulation of organ formation GO:0003156 34 0.065
Mouse
retina development in camera type eye GO:0060041 119 0.065
Mouse
cytokine biosynthetic process GO:0042089 68 0.065
negative regulation of embryonic development GO:0045992 22 0.064
negative regulation of interferon gamma production GO:0032689 18 0.063
collagen fibril organization GO:0030199 32 0.063
Mouse
cardiac muscle cell development GO:0055013 39 0.063
cartilage development GO:0051216 140 0.063
Mouse
rhythmic process GO:0048511 174 0.063
Mouse
respiratory system development GO:0060541 190 0.063
neural retina development GO:0003407 41 0.062
Mouse

Tal1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.661
disease of anatomical entity DOID:7 0 0.661
hematopoietic system disease DOID:74 0 0.661
blood coagulation disease DOID:1247 0 0.557
blood platelet disease DOID:2218 0 0.395
hemorrhagic disease DOID:2213 0 0.395
inherited blood coagulation disease DOID:2214 0 0.082