Mus musculus

0 known processes

Lrrc1

leucine rich repeat containing 1

(Aliases: KIAA4018,mKIAA4018,AU016091,MGC90936,A430093J20Rik,D030059I21)

Lrrc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amine metabolic process GO:0009308 45 0.074
cellular amine metabolic process GO:0044106 44 0.072
regulation of cellular amino acid metabolic process GO:0006521 5 0.064
regulation of cellular amine metabolic process GO:0033238 20 0.062
cellular amino acid metabolic process GO:0006520 103 0.057
cellular ketone metabolic process GO:0042180 84 0.054
positive regulation of cellular amine metabolic process GO:0033240 5 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.043
transmembrane transport GO:0055085 412 0.042
macromolecule catabolic process GO:0009057 281 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
regulation of hydrolase activity GO:0051336 246 0.039
spermatogenesis GO:0007283 284 0.039
protein catabolic process GO:0030163 221 0.039
cation transmembrane transport GO:0098655 266 0.037
ribonucleotide metabolic process GO:0009259 291 0.036
cellular lipid metabolic process GO:0044255 323 0.036
negative regulation of molecular function GO:0044092 258 0.034
nucleoside phosphate metabolic process GO:0006753 338 0.033
purine nucleotide metabolic process GO:0006163 302 0.033
peptidyl amino acid modification GO:0018193 336 0.033
purine containing compound metabolic process GO:0072521 311 0.033
small gtpase mediated signal transduction GO:0007264 97 0.032
cell adhesion GO:0007155 329 0.032
cation transport GO:0006812 399 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.032
nucleotide metabolic process GO:0009117 332 0.031
regulation of transferase activity GO:0051338 263 0.031
inorganic cation transmembrane transport GO:0098662 207 0.031
apoptotic signaling pathway GO:0097190 306 0.031
regulation of organelle organization GO:0033043 289 0.031
ras protein signal transduction GO:0007265 77 0.031
purine nucleoside metabolic process GO:0042278 241 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.029
ion transmembrane transport GO:0034220 361 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
immune effector process GO:0002252 321 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
nucleoside metabolic process GO:0009116 246 0.028
heterocycle catabolic process GO:0046700 280 0.028
organophosphate catabolic process GO:0046434 232 0.028
glycosyl compound catabolic process GO:1901658 206 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
organonitrogen compound catabolic process GO:1901565 264 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
nucleoside catabolic process GO:0009164 206 0.027
male gamete generation GO:0048232 285 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
nucleoside triphosphate metabolic process GO:0009141 230 0.026
regulation of kinase activity GO:0043549 249 0.026
cytoplasmic transport GO:0016482 234 0.026
positive regulation of protein modification process GO:0031401 299 0.026
nucleoside phosphate catabolic process GO:1901292 222 0.026
aromatic compound catabolic process GO:0019439 286 0.026
purine nucleotide catabolic process GO:0006195 211 0.025
ribonucleoside metabolic process GO:0009119 245 0.025
inorganic ion transmembrane transport GO:0098660 234 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of cell projection organization GO:0031344 206 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
negative regulation of protein metabolic process GO:0051248 282 0.025
axonogenesis GO:0007409 274 0.025
microtubule based process GO:0007017 236 0.024
purine ribonucleotide catabolic process GO:0009154 208 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
regulation of cell cycle GO:0051726 281 0.024
rho protein signal transduction GO:0007266 32 0.024
nitrogen compound transport GO:0071705 271 0.023
purine containing compound catabolic process GO:0072523 213 0.023
lymphocyte differentiation GO:0030098 242 0.023
leukocyte differentiation GO:0002521 342 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
camera type eye development GO:0043010 266 0.023
nucleotide catabolic process GO:0009166 217 0.023
regulation of neuron differentiation GO:0045664 281 0.023
regulation of ion transport GO:0043269 215 0.022
regulation of protein kinase activity GO:0045859 232 0.022
regulation of cell activation GO:0050865 289 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.022
asymmetric stem cell division GO:0098722 3 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
skin development GO:0043588 220 0.022
Mouse
ribonucleotide catabolic process GO:0009261 208 0.021
cell type specific apoptotic process GO:0097285 268 0.021
lipid biosynthetic process GO:0008610 179 0.021
oxidation reduction process GO:0055114 342 0.021
homeostasis of number of cells GO:0048872 210 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
membrane organization GO:0061024 245 0.021
wnt signaling pathway GO:0016055 188 0.021
endocytosis GO:0006897 168 0.021
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
mitotic cell cycle GO:0000278 195 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
organelle localization GO:0051640 179 0.021
Mouse
carbohydrate metabolic process GO:0005975 230 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
epithelial tube morphogenesis GO:0060562 303 0.021
Mouse
compound eye development GO:0048749 1 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
b cell activation GO:0042113 161 0.020
negative regulation of protein modification process GO:0031400 163 0.020
response to organonitrogen compound GO:0010243 246 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
regulation of protein localization GO:0032880 231 0.020
negative regulation of phosphorylation GO:0042326 166 0.020
protein ubiquitination GO:0016567 171 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
cell junction maintenance GO:0034331 4 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
phospholipid metabolic process GO:0006644 87 0.020
protein localization to organelle GO:0033365 185 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
divalent inorganic cation transport GO:0072511 178 0.019
regulation of cytokine production GO:0001817 266 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
positive regulation of cellular catabolic process GO:0031331 148 0.019
sensory perception GO:0007600 245 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
response to growth factor GO:0070848 198 0.018
positive regulation of cell development GO:0010720 237 0.018
cellular homeostasis GO:0019725 240 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
mapk cascade GO:0000165 281 0.018
glycoprotein metabolic process GO:0009100 116 0.018
microtubule cytoskeleton organization GO:0000226 157 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
developmental maturation GO:0021700 193 0.018
organelle assembly GO:0070925 177 0.018
intracellular protein transport GO:0006886 204 0.018
Mouse
maintenance of location GO:0051235 89 0.018
cell junction organization GO:0034330 77 0.018
protein maturation GO:0051604 176 0.018
guanosine containing compound catabolic process GO:1901069 144 0.017
cilium morphogenesis GO:0060271 102 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
actin cytoskeleton organization GO:0030036 220 0.017
regulation of cell migration GO:0030334 219 0.017
cell activation involved in immune response GO:0002263 126 0.017
myeloid cell differentiation GO:0030099 233 0.017
negative regulation of protein phosphorylation GO:0001933 126 0.017
epithelial cell development GO:0002064 159 0.017
Mouse
anion transport GO:0006820 177 0.017
lymphocyte activation involved in immune response GO:0002285 93 0.017
muscle cell differentiation GO:0042692 261 0.017
positive regulation of nervous system development GO:0051962 221 0.016
wound healing GO:0042060 157 0.016
Mouse
cytokine production GO:0001816 319 0.016
regulation of apoptotic signaling pathway GO:2001233 197 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
chemotaxis GO:0006935 247 0.016
Mouse
establishment or maintenance of cell polarity GO:0007163 86 0.016
neuronal action potential GO:0019228 54 0.016
spermatid differentiation GO:0048515 115 0.016
modification dependent macromolecule catabolic process GO:0043632 133 0.016
regulation of cell motility GO:2000145 236 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
regulation of nucleoside metabolic process GO:0009118 130 0.016
gonad development GO:0008406 141 0.016
regulation of hormone levels GO:0010817 211 0.016
renal system development GO:0072001 225 0.016
regulation of secretion by cell GO:1903530 249 0.016
regulation of purine nucleotide catabolic process GO:0033121 122 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
regulation of membrane potential GO:0042391 192 0.016
t cell activation GO:0042110 289 0.016
epithelial cell proliferation GO:0050673 174 0.016
response to radiation GO:0009314 165 0.016
sensory organ morphogenesis GO:0090596 242 0.016
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
action potential GO:0001508 78 0.016
developmental growth involved in morphogenesis GO:0060560 138 0.016
embryonic organ morphogenesis GO:0048562 276 0.015
Mouse
anatomical structure homeostasis GO:0060249 145 0.015
positive regulation of cell death GO:0010942 224 0.015
digestive tract development GO:0048565 190 0.015
regulation of mapk cascade GO:0043408 248 0.015
leukocyte mediated immunity GO:0002443 174 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
divalent metal ion transport GO:0070838 172 0.015
protein localization to nucleus GO:0034504 121 0.015
cellular chemical homeostasis GO:0055082 215 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
regulation of proteolysis GO:0030162 164 0.015
cation homeostasis GO:0055080 212 0.015
modification dependent protein catabolic process GO:0019941 133 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
sequestering of metal ion GO:0051238 19 0.015
organic hydroxy compound metabolic process GO:1901615 203 0.015
regulation of transmembrane transport GO:0034762 128 0.015
striated muscle tissue development GO:0014706 293 0.015
negative regulation of immune system process GO:0002683 209 0.015
dendrite development GO:0016358 115 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
leukocyte activation involved in immune response GO:0002366 126 0.015
smoothened signaling pathway GO:0007224 105 0.015
regulation of defense response GO:0031347 233 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
negative regulation of nervous system development GO:0051961 156 0.014
response to light stimulus GO:0009416 135 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of t cell activation GO:0050863 170 0.014
glucose homeostasis GO:0042593 128 0.014
neuron apoptotic process GO:0051402 142 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
circulatory system process GO:0003013 197 0.014
metal ion homeostasis GO:0055065 189 0.014
endomembrane system organization GO:0010256 147 0.014
muscle tissue development GO:0060537 308 0.014
regulation of wnt signaling pathway GO:0030111 123 0.014
regulation of neuron projection development GO:0010975 169 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.014
synaptic transmission GO:0007268 329 0.014
Mouse
regulation of gtp catabolic process GO:0033124 113 0.014
cellular ion homeostasis GO:0006873 165 0.014
regulation of anatomical structure size GO:0090066 178 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.014
regulation of response to wounding GO:1903034 189 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
Mouse
tube formation GO:0035148 140 0.014
Mouse
ossification GO:0001503 216 0.014
negative regulation of transferase activity GO:0051348 85 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
blood vessel morphogenesis GO:0048514 285 0.014
leukocyte proliferation GO:0070661 172 0.014
neuron death GO:0070997 154 0.014
blood circulation GO:0008015 195 0.014
neural tube development GO:0021915 160 0.013
Mouse
positive regulation of transferase activity GO:0051347 167 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
response to transforming growth factor beta GO:0071559 88 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
regulation of cellular response to growth factor stimulus GO:0090287 82 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
cellular response to lipid GO:0071396 145 0.013
inflammatory response GO:0006954 244 0.013
regulation of nucleotide catabolic process GO:0030811 122 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
t cell differentiation GO:0030217 174 0.013
stem cell differentiation GO:0048863 268 0.013
organelle fission GO:0048285 170 0.013
lung development GO:0030324 164 0.013
carbohydrate homeostasis GO:0033500 128 0.013
b cell differentiation GO:0030183 78 0.013
multicellular organismal signaling GO:0035637 91 0.013
oocyte construction GO:0007308 2 0.013
mitotic cell cycle process GO:1903047 159 0.013
sequestering of calcium ion GO:0051208 18 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
skeletal system development GO:0001501 356 0.013
peptide transport GO:0015833 133 0.013
response to lipopolysaccharide GO:0032496 128 0.013
respiratory system development GO:0060541 190 0.013
retina development in camera type eye GO:0060041 119 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.013
cellular protein catabolic process GO:0044257 155 0.013
regulation of metal ion transport GO:0010959 106 0.013
germ cell development GO:0007281 185 0.013
adult behavior GO:0030534 135 0.013
cell substrate adhesion GO:0031589 130 0.013
regionalization GO:0003002 337 0.013
epidermis development GO:0008544 187 0.013
Mouse
transmission of nerve impulse GO:0019226 76 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
oocyte axis specification GO:0007309 2 0.013
digestive system development GO:0055123 200 0.013
cellular protein complex assembly GO:0043623 116 0.012
actin filament organization GO:0007015 113 0.012
cognition GO:0050890 149 0.012
regulation of actin filament based process GO:0032970 99 0.012
urogenital system development GO:0001655 261 0.012
positive regulation of cell activation GO:0050867 158 0.012
cytokine mediated signaling pathway GO:0019221 115 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
regulation of system process GO:0044057 200 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
protein targeting GO:0006605 143 0.012
Mouse
response to organic cyclic compound GO:0014070 198 0.012
nuclear transport GO:0051169 139 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
myeloid cell homeostasis GO:0002262 114 0.012
single organism cell adhesion GO:0098602 156 0.012
regulation of ras gtpase activity GO:0032318 88 0.012
peptidyl tyrosine modification GO:0018212 145 0.012
dephosphorylation GO:0016311 129 0.012
positive regulation of nucleotide catabolic process GO:0030813 88 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
kidney development GO:0001822 213 0.012
positive regulation of mapk cascade GO:0043410 170 0.012
leukocyte migration GO:0050900 124 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
positive regulation of cellular component biogenesis GO:0044089 94 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
Mouse
protein processing GO:0016485 163 0.012
fat cell differentiation GO:0045444 160 0.012
tissue homeostasis GO:0001894 115 0.012
organic acid biosynthetic process GO:0016053 86 0.012
asymmetric neuroblast division GO:0055059 1 0.012
dna metabolic process GO:0006259 303 0.012
methylation GO:0032259 134 0.012
hormone secretion GO:0046879 128 0.012
positive regulation of kinase activity GO:0033674 155 0.012
spermatid development GO:0007286 108 0.012
gland development GO:0048732 330 0.012
Mouse
regulation of cell cycle process GO:0010564 160 0.012
regulation of secretion GO:0051046 274 0.012
negative regulation of organelle organization GO:0010639 90 0.012
forebrain development GO:0030900 302 0.012
protein localization to membrane GO:0072657 108 0.012
glycerolipid metabolic process GO:0046486 122 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
cellular carbohydrate metabolic process GO:0044262 119 0.012
regulation of cell growth GO:0001558 91 0.012
lymphocyte proliferation GO:0046651 164 0.011
negative regulation of cell activation GO:0050866 111 0.011
response to acid chemical GO:0001101 111 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
organic acid transport GO:0015849 101 0.011
muscle system process GO:0003012 141 0.011
mesodermal cell migration GO:0008078 4 0.011
interleukin 8 production GO:0032637 4 0.011
adaptive immune response GO:0002250 155 0.011
regulation of binding GO:0051098 111 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
chromatin organization GO:0006325 206 0.011
positive regulation of secretion GO:0051047 130 0.011
cellularization GO:0007349 1 0.011
cilium assembly GO:0042384 81 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.011
actin filament based movement GO:0030048 23 0.011
regulation of neuron apoptotic process GO:0043523 122 0.011
heart morphogenesis GO:0003007 178 0.011
regulation of neuron death GO:1901214 134 0.011
cell maturation GO:0048469 127 0.011
regulation of feeding behavior GO:0060259 3 0.011
learning or memory GO:0007611 148 0.011
respiratory tube development GO:0030323 167 0.011
myotube differentiation GO:0014902 105 0.011
protein import GO:0017038 101 0.011
amide transport GO:0042886 138 0.011
synapse organization GO:0050808 125 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
stem cell development GO:0048864 219 0.011
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.011
gtp catabolic process GO:0006184 143 0.011
peptidyl tyrosine phosphorylation GO:0018108 143 0.011
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.011
small molecule biosynthetic process GO:0044283 132 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
sensory perception of sound GO:0007605 97 0.011
multicellular organism growth GO:0035264 161 0.011
carboxylic acid transport GO:0046942 100 0.011
regulation of cellular component size GO:0032535 121 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
muscle contraction GO:0006936 101 0.011
anion transmembrane transport GO:0098656 71 0.011
rna interference GO:0016246 2 0.011
endodermal cell fate specification GO:0001714 4 0.011
establishment of organelle localization GO:0051656 122 0.011
Mouse
negative regulation of cell development GO:0010721 169 0.011
gtp metabolic process GO:0046039 144 0.011
neural tube formation GO:0001841 108 0.011
Mouse
extracellular structure organization GO:0043062 148 0.011
regulation of leukocyte proliferation GO:0070663 121 0.011
regulation of interleukin 8 production GO:0032677 3 0.011
innate immune response GO:0045087 157 0.011
cellular response to epidermal growth factor stimulus GO:0071364 4 0.011
cell growth GO:0016049 130 0.011
rhythmic process GO:0048511 174 0.011
morphogenesis of a branching structure GO:0001763 203 0.010
purine nucleoside monophosphate metabolic process GO:0009126 81 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
regulation of cell adhesion GO:0030155 154 0.010
regulation of intracellular transport GO:0032386 159 0.010
regulation of inflammatory response GO:0050727 147 0.010
organic anion transport GO:0015711 137 0.010
negative regulation of cell cycle GO:0045786 123 0.010
rhodopsin mediated signaling pathway GO:0016056 4 0.010
glycerophospholipid metabolic process GO:0006650 71 0.010
regulation of protein processing GO:0070613 96 0.010
neural precursor cell proliferation GO:0061351 121 0.010
calcium ion transport GO:0006816 159 0.010
negative regulation of kinase activity GO:0033673 81 0.010
sensory perception of mechanical stimulus GO:0050954 107 0.010
canonical wnt signaling pathway GO:0060070 130 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
cell fate commitment GO:0045165 210 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
cofactor metabolic process GO:0051186 80 0.010
negative regulation of leukocyte differentiation GO:1902106 51 0.010
protein polymerization GO:0051258 57 0.010

Lrrc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
immune system disease DOID:2914 0 0.014
musculoskeletal system disease DOID:17 0 0.013
disease of metabolism DOID:0014667 0 0.012
cardiovascular system disease DOID:1287 0 0.011
central nervous system disease DOID:331 0 0.011
physical disorder DOID:0080015 0 0.010
congenital nervous system abnormality DOID:2490 0 0.010
hematopoietic system disease DOID:74 0 0.010