Mus musculus

35 known processes

Tph1

tryptophan hydroxylase 1

(Aliases: Tph)

Tph1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.482
amine metabolic process GO:0009308 45 0.390
Worm
negative regulation of cell proliferation GO:0008285 296 0.314
striated muscle tissue development GO:0014706 293 0.293
regulation of cellular amine metabolic process GO:0033238 20 0.285
positive regulation of apoptotic process GO:0043065 217 0.241
blood vessel morphogenesis GO:0048514 285 0.235
inflammatory response GO:0006954 244 0.211
muscle tissue development GO:0060537 308 0.206
muscle cell development GO:0055001 133 0.204
cellular amine metabolic process GO:0044106 44 0.191
Worm
regulation of cellular amino acid metabolic process GO:0006521 5 0.181
cellular homeostasis GO:0019725 240 0.154
regulation of secretion by cell GO:1903530 249 0.146
cytokine production GO:0001816 319 0.140
positive regulation of protein phosphorylation GO:0001934 242 0.139
regulation of defense response GO:0031347 233 0.138
regulation of cellular ketone metabolic process GO:0010565 66 0.136
cell type specific apoptotic process GO:0097285 268 0.135
apoptotic signaling pathway GO:0097190 306 0.135
cellular lipid metabolic process GO:0044255 323 0.135
wound healing GO:0042060 157 0.134
cellular chemical homeostasis GO:0055082 215 0.128
lipid biosynthetic process GO:0008610 179 0.126
muscle fiber development GO:0048747 76 0.121
positive regulation of programmed cell death GO:0043068 218 0.120
regulation of homeostatic process GO:0032844 182 0.119
extracellular structure organization GO:0043062 148 0.117
regulation of organ morphogenesis GO:2000027 144 0.114
regulation of protein localization GO:0032880 231 0.113
circulatory system process GO:0003013 197 0.112
Mouse
divalent inorganic cation transport GO:0072511 178 0.110
immune effector process GO:0002252 321 0.108
regulation of response to wounding GO:1903034 189 0.106
regulation of system process GO:0044057 200 0.106
Mouse
neuron migration GO:0001764 122 0.104
gland development GO:0048732 330 0.101
cytoplasmic transport GO:0016482 234 0.100
negative regulation of protein metabolic process GO:0051248 282 0.100
cation transport GO:0006812 399 0.098
camera type eye development GO:0043010 266 0.097
Mouse
response to lipopolysaccharide GO:0032496 128 0.093
axonogenesis GO:0007409 274 0.093
mapk cascade GO:0000165 281 0.091
regulation of anatomical structure size GO:0090066 178 0.090
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.086
negative regulation of nervous system development GO:0051961 156 0.086
organic hydroxy compound metabolic process GO:1901615 203 0.086
Mouse Worm Fly
morphogenesis of a branching epithelium GO:0061138 193 0.086
response to acid chemical GO:0001101 111 0.084
synaptic transmission GO:0007268 329 0.083
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.082
kidney epithelium development GO:0072073 121 0.081
positive regulation of cell activation GO:0050867 158 0.081
response to organonitrogen compound GO:0010243 246 0.080
blastocyst development GO:0001824 80 0.080
negative regulation of cell development GO:0010721 169 0.079
positive regulation of cell development GO:0010720 237 0.079
cellular response to organonitrogen compound GO:0071417 145 0.078
placenta development GO:0001890 140 0.078
hindbrain development GO:0030902 128 0.077
cellular response to insulin stimulus GO:0032869 78 0.077
regulation of inflammatory response GO:0050727 147 0.076
negative regulation of phosphorus metabolic process GO:0010563 184 0.075
positive regulation of protein modification process GO:0031401 299 0.075
skeletal system development GO:0001501 356 0.075
positive regulation of cell death GO:0010942 224 0.074
regulation of cell motility GO:2000145 236 0.073
protein kinase b signaling GO:0043491 74 0.073
regulation of neuron differentiation GO:0045664 281 0.072
lymphocyte differentiation GO:0030098 242 0.072
positive regulation of mapk cascade GO:0043410 170 0.072
neuron apoptotic process GO:0051402 142 0.072
positive regulation of nervous system development GO:0051962 221 0.071
regulation of epithelial cell proliferation GO:0050678 141 0.071
skeletal muscle organ development GO:0060538 163 0.070
defense response to other organism GO:0098542 197 0.069
negative regulation of homeostatic process GO:0032845 71 0.068
response to molecule of bacterial origin GO:0002237 143 0.068
sequestering of metal ion GO:0051238 19 0.067
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.067
myotube differentiation GO:0014902 105 0.066
regulation of secretion GO:0051046 274 0.064
regulation of hormone levels GO:0010817 211 0.063
skeletal muscle fiber development GO:0048741 58 0.062
peptide transport GO:0015833 133 0.062
regulation of cell activation GO:0050865 289 0.061
cellular response to peptide hormone stimulus GO:0071375 92 0.061
nitrogen compound transport GO:0071705 271 0.060
heart process GO:0003015 94 0.060
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.059
regionalization GO:0003002 337 0.059
cellular ion homeostasis GO:0006873 165 0.058
leukocyte differentiation GO:0002521 342 0.058
connective tissue development GO:0061448 179 0.058
cell fate commitment GO:0045165 210 0.057
regulation of interleukin 6 production GO:0032675 55 0.057
sequestering of calcium ion GO:0051208 18 0.057
morphogenesis of a branching structure GO:0001763 203 0.056
myeloid cell differentiation GO:0030099 233 0.056
reactive oxygen species metabolic process GO:0072593 84 0.056
muscle cell differentiation GO:0042692 261 0.056
regulation of metal ion transport GO:0010959 106 0.055
negative regulation of cellular amine metabolic process GO:0033239 1 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
fat cell differentiation GO:0045444 160 0.055
amide transport GO:0042886 138 0.055
sensory perception GO:0007600 245 0.054
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.054
response to peptide hormone GO:0043434 127 0.054
negative regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061179 4 0.053
regulation of mapk cascade GO:0043408 248 0.052
carbohydrate metabolic process GO:0005975 230 0.052
calcium ion transport GO:0006816 159 0.052
negative regulation of molecular function GO:0044092 258 0.051
metal ion homeostasis GO:0055065 189 0.050
maintenance of location GO:0051235 89 0.049
Worm
response to extracellular stimulus GO:0009991 127 0.049
developmental growth involved in morphogenesis GO:0060560 138 0.049
negative regulation of intracellular signal transduction GO:1902532 167 0.049
axon guidance GO:0007411 141 0.048
central nervous system neuron differentiation GO:0021953 162 0.048
regulation of neuron apoptotic process GO:0043523 122 0.048
negative regulation of hydrolase activity GO:0051346 71 0.047
cation homeostasis GO:0055080 212 0.047
divalent inorganic cation homeostasis GO:0072507 138 0.047
oxidation reduction process GO:0055114 342 0.047
cation transmembrane transport GO:0098655 266 0.047
positive regulation of protein kinase activity GO:0045860 144 0.046
striated muscle cell development GO:0055002 125 0.046
epithelial cell development GO:0002064 159 0.046
stem cell proliferation GO:0072089 117 0.046
cellular response to growth factor stimulus GO:0071363 197 0.046
Worm
membrane organization GO:0061024 245 0.046
negative regulation of cellular component organization GO:0051129 194 0.045
single organismal cell cell adhesion GO:0016337 131 0.045
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.045
ear morphogenesis GO:0042471 118 0.045
negative regulation of cellular protein metabolic process GO:0032269 247 0.045
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.045
Worm
multicellular organismal homeostasis GO:0048871 164 0.044
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.044
extracellular matrix organization GO:0030198 147 0.044
adult behavior GO:0030534 135 0.044
regulation of protein kinase activity GO:0045859 232 0.043
protein maturation GO:0051604 176 0.043
regulation of kinase activity GO:0043549 249 0.043
embryonic placenta development GO:0001892 98 0.043
tube formation GO:0035148 140 0.043
regulation of cell projection organization GO:0031344 206 0.043
response to growth factor GO:0070848 198 0.043
Worm
divalent metal ion transport GO:0070838 172 0.042
transmembrane transport GO:0055085 412 0.042
regulation of ion transport GO:0043269 215 0.042
positive regulation of epithelial cell proliferation GO:0050679 68 0.042
hexose metabolic process GO:0019318 98 0.041
regulation of hormone secretion GO:0046883 88 0.041
telencephalon development GO:0021537 186 0.041
positive regulation of secretion GO:0051047 130 0.041
response to calcium ion GO:0051592 20 0.041
regulation of skeletal muscle fiber development GO:0048742 36 0.041
regulation of protein serine threonine kinase activity GO:0071900 157 0.041
ossification GO:0001503 216 0.040
positive regulation of secretion by cell GO:1903532 114 0.040
response to nutrient levels GO:0031667 109 0.040
negative regulation of phosphorylation GO:0042326 166 0.040
epithelial cell proliferation GO:0050673 174 0.040
cellular response to inorganic substance GO:0071241 37 0.040
positive regulation of interleukin 6 production GO:0032755 37 0.040
monosaccharide metabolic process GO:0005996 106 0.039
syncytium formation by plasma membrane fusion GO:0000768 42 0.039
peptidyl amino acid modification GO:0018193 336 0.039
regulation of protein kinase b signaling GO:0051896 56 0.039
regulation of cell cycle GO:0051726 281 0.039
carbohydrate homeostasis GO:0033500 128 0.039
response to inorganic substance GO:0010035 96 0.039
regulation of hydrolase activity GO:0051336 246 0.039
regulation of peptide transport GO:0090087 91 0.039
male sex differentiation GO:0046661 109 0.039
learning or memory GO:0007611 148 0.039
Mouse
regulation of transferase activity GO:0051338 263 0.038
regulation of muscle tissue development GO:1901861 97 0.038
stem cell differentiation GO:0048863 268 0.038
cellular calcium ion homeostasis GO:0006874 119 0.038
response to peptide GO:1901652 136 0.038
chemotaxis GO:0006935 247 0.037
cell maturation GO:0048469 127 0.037
limb development GO:0060173 166 0.037
regulation of body fluid levels GO:0050878 162 0.037
membrane lipid biosynthetic process GO:0046467 32 0.037
response to organic cyclic compound GO:0014070 198 0.037
regulation of lipid metabolic process GO:0019216 118 0.037
regulation of membrane potential GO:0042391 192 0.036
developmental maturation GO:0021700 193 0.036
positive regulation of lymphocyte activation GO:0051251 140 0.036
cellular response to hormone stimulus GO:0032870 150 0.036
regulation of establishment of protein localization GO:0070201 181 0.036
response to insulin GO:0032868 100 0.035
cellular response to acid chemical GO:0071229 68 0.035
reactive nitrogen species metabolic process GO:2001057 0 0.035
regulation of neuron projection development GO:0010975 169 0.035
negative regulation of response to wounding GO:1903035 77 0.035
regulation of proteolysis GO:0030162 164 0.035
monocarboxylic acid metabolic process GO:0032787 191 0.035
alpha beta t cell activation GO:0046631 91 0.035
somitogenesis GO:0001756 69 0.035
single organism cell adhesion GO:0098602 156 0.035
respiratory system development GO:0060541 190 0.035
epithelial cell morphogenesis GO:0003382 41 0.035
neuron death GO:0070997 154 0.034
i kappab kinase nf kappab signaling GO:0007249 85 0.034
bone development GO:0060348 120 0.034
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.034
defense response to bacterium GO:0042742 119 0.034
digestive system development GO:0055123 200 0.034
digestive tract morphogenesis GO:0048546 147 0.034
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.034
cell adhesion GO:0007155 329 0.034
ear development GO:0043583 200 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
extrinsic apoptotic signaling pathway GO:0097191 126 0.033
erk1 and erk2 cascade GO:0070371 77 0.033
rhythmic process GO:0048511 174 0.033
Fly
cellular response to cytokine stimulus GO:0071345 189 0.033
urogenital system development GO:0001655 261 0.033
cellular response to lipid GO:0071396 145 0.032
skin development GO:0043588 220 0.032
regulation of angiogenesis GO:0045765 81 0.032
alpha beta t cell differentiation GO:0046632 69 0.032
skeletal system morphogenesis GO:0048705 203 0.032
positive regulation of neuron differentiation GO:0045666 141 0.032
positive regulation of keratinocyte proliferation GO:0010838 4 0.032
insulin secretion GO:0030073 89 0.032
myotube cell development GO:0014904 60 0.032
pancreatic pp cell fate commitment GO:0003329 2 0.032
stem cell maintenance GO:0019827 130 0.031
gastrulation GO:0007369 116 0.031
cellular response to peptide GO:1901653 92 0.031
nephron epithelium development GO:0072009 92 0.031
regulation of protein complex assembly GO:0043254 83 0.031
macromolecule catabolic process GO:0009057 281 0.031
myoblast differentiation GO:0045445 52 0.031
positive regulation of transferase activity GO:0051347 167 0.031
phenol containing compound metabolic process GO:0018958 60 0.030
Mouse Worm Fly
cell activation involved in immune response GO:0002263 126 0.030
interleukin 6 production GO:0032635 58 0.030
regulation of cell migration GO:0030334 219 0.030
adaptive immune response GO:0002250 155 0.030
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.030
Worm
sphingolipid biosynthetic process GO:0030148 26 0.030
glucose homeostasis GO:0042593 128 0.029
regulation of intracellular transport GO:0032386 159 0.029
positive regulation of homeostatic process GO:0032846 64 0.029
hormone secretion GO:0046879 128 0.029
positive regulation of protein kinase b signaling GO:0051897 32 0.029
renal system process GO:0003014 48 0.029
hemostasis GO:0007599 78 0.029
multi multicellular organism process GO:0044706 109 0.029
Worm
b cell mediated immunity GO:0019724 71 0.028
peptide secretion GO:0002790 114 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.028
formation of primary germ layer GO:0001704 77 0.028
auditory receptor cell fate specification GO:0042667 1 0.028
regulation of neural precursor cell proliferation GO:2000177 70 0.028
gliogenesis GO:0042063 141 0.028
intermediate filament based process GO:0045103 27 0.028
odontogenesis of dentin containing tooth GO:0042475 66 0.028
multicellular organismal signaling GO:0035637 91 0.028
defense response to gram positive bacterium GO:0050830 50 0.028
morphogenesis of embryonic epithelium GO:0016331 159 0.028
regulation of epidermal cell differentiation GO:0045604 21 0.028
regulation of ion homeostasis GO:2000021 64 0.028
positive regulation of lymphocyte differentiation GO:0045621 61 0.027
cartilage development GO:0051216 140 0.027
mitotic cell cycle process GO:1903047 159 0.027
regulation of synaptic plasticity GO:0048167 87 0.027
embryonic skeletal system development GO:0048706 120 0.027
bone morphogenesis GO:0060349 78 0.027
cellular nitrogen compound catabolic process GO:0044270 280 0.027
regulation of organelle organization GO:0033043 289 0.027
embryonic epithelial tube formation GO:0001838 130 0.027
cellular amino acid metabolic process GO:0006520 103 0.027
Mouse Worm
cellular protein complex assembly GO:0043623 116 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.026
Worm
regulation of protein transport GO:0051223 163 0.026
myeloid leukocyte differentiation GO:0002573 119 0.026
response to drug GO:0042493 75 0.026
cellular response to external stimulus GO:0071496 88 0.026
regulation of calcium ion transport GO:0051924 69 0.026
stem cell development GO:0048864 219 0.026
asymmetric stem cell division GO:0098722 3 0.026
bmp signaling pathway GO:0030509 93 0.026
forebrain development GO:0030900 302 0.025
nuclear transport GO:0051169 139 0.025
ceramide biosynthetic process GO:0046513 20 0.025
response to oxygen levels GO:0070482 62 0.025
leukocyte activation involved in immune response GO:0002366 126 0.025
ion transmembrane transport GO:0034220 361 0.025
mesenchymal cell development GO:0014031 93 0.025
positive regulation of lymphocyte proliferation GO:0050671 70 0.025
salivary gland development GO:0007431 37 0.025
regulation of wound healing GO:0061041 40 0.025
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.025
positive regulation of t cell activation GO:0050870 101 0.024
negative regulation of cell motility GO:2000146 61 0.024
cardiac muscle tissue development GO:0048738 130 0.024
striated muscle contraction GO:0006941 45 0.024
cellular response to amino acid stimulus GO:0071230 29 0.024
nephron development GO:0072006 109 0.024
cellular metal ion homeostasis GO:0006875 151 0.024
positive regulation of defense response GO:0031349 124 0.024
positive regulation of cellular component biogenesis GO:0044089 94 0.024
protein localization to organelle GO:0033365 185 0.024
production of molecular mediator of immune response GO:0002440 103 0.024
single organism nuclear import GO:1902593 95 0.024
regulation of mitotic cell cycle GO:0007346 126 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
positive regulation of cell migration GO:0030335 109 0.024
calcium ion transport into cytosol GO:0060402 48 0.024
protein targeting GO:0006605 143 0.024
somite development GO:0061053 81 0.024
positive regulation of cytokine production GO:0001819 174 0.023
compound eye development GO:0048749 1 0.023
hippocampus development GO:0021766 52 0.023
olfactory learning GO:0008355 2 0.023
response to transforming growth factor beta GO:0071559 88 0.023
Worm
leukocyte migration GO:0050900 124 0.023
digestive tract development GO:0048565 190 0.023
epithelial tube morphogenesis GO:0060562 303 0.023
mitochondrion organization GO:0007005 134 0.023
regulation of fibroblast proliferation GO:0048145 34 0.023
heart morphogenesis GO:0003007 178 0.023
regulation of feeding behavior GO:0060259 3 0.023
Worm
leukocyte mediated immunity GO:0002443 174 0.023
regulation of transmembrane transport GO:0034762 128 0.022
blood circulation GO:0008015 195 0.022
Mouse
negative regulation of defense response GO:0031348 77 0.022
b cell activation GO:0042113 161 0.022
regulation of myoblast differentiation GO:0045661 29 0.022
neuromuscular process GO:0050905 99 0.022
sensory system development GO:0048880 3 0.022
regulation of morphogenesis of a branching structure GO:0060688 53 0.022
organic cyclic compound catabolic process GO:1901361 295 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.022
cytosolic calcium ion homeostasis GO:0051480 70 0.022
regulation of map kinase activity GO:0043405 120 0.022
cellular response to molecule of bacterial origin GO:0071219 83 0.022
negative regulation of cell cycle GO:0045786 123 0.022
dna recombination GO:0006310 92 0.022
regulation of muscle system process GO:0090257 80 0.022
intermediate filament cytoskeleton organization GO:0045104 26 0.022
purine nucleotide metabolic process GO:0006163 302 0.022
regulation of vasculature development GO:1901342 88 0.022
regulation of b cell activation GO:0050864 81 0.022
synapse organization GO:0050808 125 0.022
positive regulation of angiogenesis GO:0045766 46 0.022
dendrite development GO:0016358 115 0.021
t cell differentiation GO:0030217 174 0.021
positive regulation of ion transport GO:0043270 65 0.021
protein secretion GO:0009306 111 0.021
membrane lipid metabolic process GO:0006643 53 0.021
tendon cell differentiation GO:0035990 4 0.021
regulation of vesicle mediated transport GO:0060627 139 0.021
circadian rhythm GO:0007623 114 0.021
Fly
transmission of nerve impulse GO:0019226 76 0.021
negative regulation of epithelial cell proliferation GO:0050680 64 0.021
regulation of interferon gamma production GO:0032649 57 0.021
negative regulation of inflammatory response GO:0050728 61 0.021
male gamete generation GO:0048232 285 0.021
endocytosis GO:0006897 168 0.021
regulation of blood circulation GO:1903522 93 0.021
Mouse
cytosolic calcium ion transport GO:0060401 48 0.021
peripheral nervous system neuron axonogenesis GO:0048936 3 0.021
trophectodermal cell differentiation GO:0001829 21 0.021
cranial nerve development GO:0021545 41 0.020
establishment of protein localization to organelle GO:0072594 118 0.020
multicellular organismal response to stress GO:0033555 62 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
coagulation GO:0050817 78 0.020
response to monosaccharide GO:0034284 67 0.020
lung development GO:0030324 164 0.020
interspecies interaction between organisms GO:0044419 83 0.020
regulation of cytokine production GO:0001817 266 0.020
t cell activation GO:0042110 289 0.020
regulation of stem cell proliferation GO:0072091 78 0.020
limbic system development GO:0021761 72 0.020
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.020
angiogenesis GO:0001525 201 0.020
regulation of t cell activation GO:0050863 170 0.020
cell differentiation involved in embryonic placenta development GO:0060706 26 0.020
endodermal cell fate specification GO:0001714 4 0.020
positive regulation of protein transport GO:0051222 93 0.020
regulation of leukocyte apoptotic process GO:2000106 56 0.020
positive regulation of leukocyte differentiation GO:1902107 86 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
heart contraction GO:0060047 93 0.020
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.020
asymmetric neuroblast division GO:0055059 1 0.019
spermatogenesis GO:0007283 284 0.019
protein oligomerization GO:0051259 67 0.019
collagen metabolic process GO:0032963 17 0.019
skeletal muscle cell differentiation GO:0035914 66 0.019
multicellular organism growth GO:0035264 161 0.019
leukocyte apoptotic process GO:0071887 71 0.019
endocrine system development GO:0035270 98 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.019
regulation of erk1 and erk2 cascade GO:0070372 71 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.019
engulfment of apoptotic cell GO:0043652 3 0.019
acute inflammatory response GO:0002526 41 0.019
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.019
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.019
male gonad development GO:0008584 88 0.019
guanosine containing compound metabolic process GO:1901068 144 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
lymphocyte mediated immunity GO:0002449 139 0.019
membrane depolarization GO:0051899 64 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
glycerolipid biosynthetic process GO:0045017 50 0.018
chromatin modification GO:0016568 187 0.018
muscle cell proliferation GO:0033002 52 0.018
mesoderm development GO:0007498 100 0.018
appendage morphogenesis GO:0035107 149 0.018
tube closure GO:0060606 91 0.018
protein localization to nucleus GO:0034504 121 0.018
regulation of peptide hormone secretion GO:0090276 75 0.018
inner ear morphogenesis GO:0042472 101 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
histone modification GO:0016570 159 0.018
transdifferentiation GO:0060290 1 0.018
mesoderm morphogenesis GO:0048332 64 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.018
regulation of cellular response to growth factor stimulus GO:0090287 82 0.018
Worm
organelle localization GO:0051640 179 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
Mouse
heterocycle catabolic process GO:0046700 280 0.018
sensory perception of pain GO:0019233 47 0.018
trabecular meshwork development GO:0002930 2 0.018
histone acetylation GO:0016573 41 0.018
neural precursor cell proliferation GO:0061351 121 0.018
cellular response to carbohydrate stimulus GO:0071322 50 0.018
regulation of circadian sleep wake cycle GO:0042749 3 0.018
Fly
kidney morphogenesis GO:0060993 83 0.018
organelle fission GO:0048285 170 0.018
ameboidal type cell migration GO:0001667 128 0.017
lens development in camera type eye GO:0002088 62 0.017
intracellular protein transport GO:0006886 204 0.017
hexose transport GO:0008645 56 0.017
pancreas development GO:0031016 57 0.017
regulation of myotube differentiation GO:0010830 62 0.017
mesenchyme development GO:0060485 152 0.017
cellular response to abiotic stimulus GO:0071214 56 0.017
learning GO:0007612 98 0.017
Mouse
negative regulation of protein modification process GO:0031400 163 0.017
negative regulation of cell fate specification GO:0009996 4 0.017
regulation of interleukin 1 alpha production GO:0032650 4 0.017
protein catabolic process GO:0030163 221 0.017
negative regulation of multi organism process GO:0043901 68 0.017
response to amino acid GO:0043200 37 0.017
regulation of organ formation GO:0003156 34 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
response to starvation GO:0042594 65 0.017
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.017
response to light stimulus GO:0009416 135 0.017
negative regulation of immune system process GO:0002683 209 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.016
Mouse Worm Fly
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.016
regulation of glucose metabolic process GO:0010906 60 0.016
muscle system process GO:0003012 141 0.016
regulation of ion transmembrane transport GO:0034765 119 0.016
metanephros development GO:0001656 79 0.016
forebrain generation of neurons GO:0021872 63 0.016
phagocytosis GO:0006909 66 0.016
positive regulation of glial cell proliferation GO:0060252 4 0.016
cerebral cortex neuron differentiation GO:0021895 19 0.016
purine containing compound metabolic process GO:0072521 311 0.016
jak stat cascade GO:0007259 42 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
positive regulation of inflammatory response GO:0050729 47 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
mesodermal cell fate commitment GO:0001710 17 0.016
purine containing compound catabolic process GO:0072523 213 0.016
small molecule biosynthetic process GO:0044283 132 0.016
odontogenesis GO:0042476 78 0.016
hemangioblast cell differentiation GO:0060217 1 0.016
hepaticobiliary system development GO:0061008 67 0.016
regulation of neuron death GO:1901214 134 0.016
immunoglobulin production GO:0002377 73 0.016
leukocyte proliferation GO:0070661 172 0.016
chromatin organization GO:0006325 206 0.016
cellular response to starvation GO:0009267 57 0.016
regulation of cell cycle process GO:0010564 160 0.016
regulation of cytoplasmic transport GO:1903649 112 0.016

Tph1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.021