Mus musculus

105 known processes

Brdt

bromodomain, testis-specific

(Aliases: Brd6,7420412D09Rik,Fsrg3)

Brdt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male gamete generation GO:0048232 285 0.108
carbohydrate metabolic process GO:0005975 230 0.077
dna metabolic process GO:0006259 303 0.067
cellular ketone metabolic process GO:0042180 84 0.064
male meiosis GO:0007140 37 0.064
spermatogenesis GO:0007283 284 0.063
cation transport GO:0006812 399 0.052
germ cell development GO:0007281 185 0.045
transmembrane transport GO:0055085 412 0.043
cellular lipid metabolic process GO:0044255 323 0.043
cellular response to dna damage stimulus GO:0006974 207 0.040
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
dna repair GO:0006281 107 0.039
spermatid differentiation GO:0048515 115 0.038
organelle fission GO:0048285 170 0.037
regulation of organelle organization GO:0033043 289 0.037
protein ubiquitination GO:0016567 171 0.037
spermatid development GO:0007286 108 0.036
gliogenesis GO:0042063 141 0.035
cellular response to cytokine stimulus GO:0071345 189 0.035
regulation of transferase activity GO:0051338 263 0.035
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
glycoprotein metabolic process GO:0009100 116 0.032
nuclear division GO:0000280 158 0.032
protein modification by small protein conjugation GO:0032446 187 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.032
positive regulation of cellular amine metabolic process GO:0033240 5 0.032
cellular amino acid metabolic process GO:0006520 103 0.031
negative regulation of phosphorylation GO:0042326 166 0.031
positive regulation of protein modification process GO:0031401 299 0.031
macromolecule methylation GO:0043414 120 0.031
synapsis GO:0007129 34 0.030
regulation of cellular ketone metabolic process GO:0010565 66 0.030
mitotic cell cycle GO:0000278 195 0.030
methylation GO:0032259 134 0.029
protein modification by small protein conjugation or removal GO:0070647 207 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
meiotic cell cycle GO:0051321 122 0.027
muscle tissue development GO:0060537 308 0.027
reactive oxygen species metabolic process GO:0072593 84 0.027
nucleobase containing small molecule metabolic process GO:0055086 352 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
chromosome organization involved in meiosis GO:0070192 39 0.026
cation homeostasis GO:0055080 212 0.026
meiosis i GO:0007127 60 0.026
metal ion homeostasis GO:0055065 189 0.025
meiotic nuclear division GO:0007126 115 0.025
cellular ion homeostasis GO:0006873 165 0.025
cation transmembrane transport GO:0098655 266 0.025
intrinsic apoptotic signaling pathway GO:0097193 132 0.025
regulation of defense response GO:0031347 233 0.025
male meiosis i GO:0007141 16 0.025
ribose phosphate metabolic process GO:0019693 291 0.024
amine metabolic process GO:0009308 45 0.024
negative regulation of intracellular signal transduction GO:1902532 167 0.024
positive regulation of cell death GO:0010942 224 0.024
pirna metabolic process GO:0034587 12 0.024
regulation of intracellular transport GO:0032386 159 0.024
glial cell differentiation GO:0010001 131 0.023
positive regulation of nervous system development GO:0051962 221 0.023
lymphocyte differentiation GO:0030098 242 0.023
macromolecule catabolic process GO:0009057 281 0.023
regulation of cell cycle process GO:0010564 160 0.023
regulation of cell migration GO:0030334 219 0.023
negative regulation of phosphate metabolic process GO:0045936 184 0.023
g protein coupled receptor signaling pathway GO:0007186 243 0.022
cytoplasmic transport GO:0016482 234 0.022
cell type specific apoptotic process GO:0097285 268 0.022
cellular protein catabolic process GO:0044257 155 0.022
regulation of binding GO:0051098 111 0.022
Mouse
leukocyte differentiation GO:0002521 342 0.021
membrane organization GO:0061024 245 0.021
negative regulation of immune system process GO:0002683 209 0.021
fat cell differentiation GO:0045444 160 0.021
apoptotic signaling pathway GO:0097190 306 0.020
cellular homeostasis GO:0019725 240 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
mapk cascade GO:0000165 281 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
t cell differentiation GO:0030217 174 0.020
protein maturation GO:0051604 176 0.020
oxidation reduction process GO:0055114 342 0.020
cell adhesion GO:0007155 329 0.020
regulation of ion transport GO:0043269 215 0.020
endomembrane system organization GO:0010256 147 0.020
sulfur compound metabolic process GO:0006790 100 0.019
inorganic ion transmembrane transport GO:0098660 234 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
regulation of protein kinase activity GO:0045859 232 0.019
protein catabolic process GO:0030163 221 0.019
positive regulation of organelle organization GO:0010638 128 0.019
protein methylation GO:0006479 81 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
meiotic cell cycle process GO:1903046 77 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.018
regulation of protein localization GO:0032880 231 0.018
immune effector process GO:0002252 321 0.018
regulation of proteolysis GO:0030162 164 0.018
negative regulation of protein phosphorylation GO:0001933 126 0.018
nitrogen compound transport GO:0071705 271 0.018
intracellular mrna localization GO:0008298 4 0.018
neuronal action potential GO:0019228 54 0.018
ion transmembrane transport GO:0034220 361 0.018
response to temperature stimulus GO:0009266 55 0.018
cellular chemical homeostasis GO:0055082 215 0.018
negative regulation of cell cycle GO:0045786 123 0.018
protein alkylation GO:0008213 81 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
regulation of membrane potential GO:0042391 192 0.018
connective tissue development GO:0061448 179 0.018
ossification GO:0001503 216 0.018
fertilization GO:0009566 127 0.018
cellular metal ion homeostasis GO:0006875 151 0.018
negative regulation of molecular function GO:0044092 258 0.018
regulation of t cell activation GO:0050863 170 0.018
cellular response to peptide GO:1901653 92 0.017
organelle localization GO:0051640 179 0.017
intracellular protein transport GO:0006886 204 0.017
regulation of lipid metabolic process GO:0019216 118 0.017
negative regulation of protein modification process GO:0031400 163 0.017
adaptive immune response GO:0002250 155 0.017
regulation of cell cycle GO:0051726 281 0.017
regulation of hormone levels GO:0010817 211 0.017
regulation of mapk cascade GO:0043408 248 0.017
leukocyte mediated cytotoxicity GO:0001909 62 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
inflammatory response GO:0006954 244 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
nucleotide metabolic process GO:0009117 332 0.016
lipid biosynthetic process GO:0008610 179 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
negative regulation of apoptotic signaling pathway GO:2001234 104 0.016
sensory organ morphogenesis GO:0090596 242 0.016
protein targeting GO:0006605 143 0.016
positive regulation of innate immune response GO:0045089 80 0.016
organic anion transport GO:0015711 137 0.016
proteoglycan metabolic process GO:0006029 38 0.016
cellular amine metabolic process GO:0044106 44 0.016
positive regulation of cytokine production GO:0001819 174 0.016
forebrain development GO:0030900 302 0.015
regulation of secretion GO:0051046 274 0.015
lipid transport GO:0006869 98 0.015
innate immune response GO:0045087 157 0.015
dna methylation involved in gamete generation GO:0043046 15 0.015
oocyte axis specification GO:0007309 2 0.015
oocyte construction GO:0007308 2 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.015
glycerolipid metabolic process GO:0046486 122 0.015
organelle assembly GO:0070925 177 0.015
homeostasis of number of cells GO:0048872 210 0.015
renal system development GO:0072001 225 0.015
ribonucleotide metabolic process GO:0009259 291 0.015
multicellular organism growth GO:0035264 161 0.015
microtubule based process GO:0007017 236 0.015
endocytosis GO:0006897 168 0.015
positive regulation of defense response GO:0031349 124 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of kinase activity GO:0043549 249 0.015
negative regulation of mapk cascade GO:0043409 65 0.015
negative regulation of cellular component organization GO:0051129 194 0.015
regulation of voltage gated calcium channel activity GO:1901385 4 0.014
response to oxidative stress GO:0006979 123 0.014
positive regulation of kinase activity GO:0033674 155 0.014
regulation of translation GO:0006417 71 0.014
mitochondrion organization GO:0007005 134 0.014
t cell activation GO:0042110 289 0.014
protein processing GO:0016485 163 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
transition metal ion homeostasis GO:0055076 54 0.014
cell fate commitment GO:0045165 210 0.014
Worm
purine containing compound metabolic process GO:0072521 311 0.014
regulation of transmembrane transport GO:0034762 128 0.014
sequestering of calcium ion GO:0051208 18 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
male genitalia morphogenesis GO:0048808 4 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
regulation of cell motility GO:2000145 236 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
maternal determination of anterior posterior axis embryo GO:0008358 2 0.014
regulation of leukocyte differentiation GO:1902105 159 0.014
peptidyl serine modification GO:0018209 83 0.014
leukocyte mediated immunity GO:0002443 174 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
skeletal system development GO:0001501 356 0.014
modification dependent macromolecule catabolic process GO:0043632 133 0.014
muscle system process GO:0003012 141 0.013
positive regulation of mapk cascade GO:0043410 170 0.013
cellular nitrogen compound catabolic process GO:0044270 280 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
negative regulation of cell cycle process GO:0010948 69 0.013
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
neuron death GO:0070997 154 0.013
sensory perception GO:0007600 245 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.013
protein localization to organelle GO:0033365 185 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
male anatomical structure morphogenesis GO:0090598 4 0.013
positive regulation of cell development GO:0010720 237 0.013
glycosylation GO:0070085 62 0.013
cellular protein complex assembly GO:0043623 116 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
mrna metabolic process GO:0016071 84 0.013
cellular response to hormone stimulus GO:0032870 150 0.013
rhythmic process GO:0048511 174 0.013
positive regulation of transferase activity GO:0051347 167 0.013
divalent inorganic cation transport GO:0072511 178 0.013
cartilage development GO:0051216 140 0.013
mitotic cell cycle process GO:1903047 159 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
negative regulation of cell proliferation GO:0008285 296 0.012
rna interference GO:0016246 2 0.012
regulation of innate immune response GO:0045088 91 0.012
exocytosis GO:0006887 121 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
aromatic compound catabolic process GO:0019439 286 0.012
telencephalon development GO:0021537 186 0.012
establishment of synaptic vesicle localization GO:0097480 57 0.012
organic acid transport GO:0015849 101 0.012
modification dependent protein catabolic process GO:0019941 133 0.012
respiratory system development GO:0060541 190 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of ion transmembrane transport GO:0034765 119 0.012
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.012
regulation of neuron differentiation GO:0045664 281 0.012
regulation of endopeptidase activity GO:0052548 89 0.012
oocyte anterior posterior axis specification GO:0007314 2 0.012
regulation of cell activation GO:0050865 289 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of protein catabolic process GO:0042176 108 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
divalent metal ion transport GO:0070838 172 0.012
covalent chromatin modification GO:0016569 163 0.012
Mouse
regulation of nucleocytoplasmic transport GO:0046822 73 0.012
regulation of cellular response to stress GO:0080135 159 0.012
regionalization GO:0003002 337 0.012
Fly
negative regulation of nervous system development GO:0051961 156 0.011
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.011
synaptic vesicle localization GO:0097479 59 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.011
stem cell maintenance GO:0019827 130 0.011
negative regulation of cell development GO:0010721 169 0.011
circulatory system process GO:0003013 197 0.011
chondrocyte differentiation GO:0002062 72 0.011
nucleoside metabolic process GO:0009116 246 0.011
wnt signaling pathway GO:0016055 188 0.011
muscle cell differentiation GO:0042692 261 0.011
regulation of mitotic cell cycle GO:0007346 126 0.011
neural precursor cell proliferation GO:0061351 121 0.011
single organism nuclear import GO:1902593 95 0.011
sequestering of metal ion GO:0051238 19 0.011
positive regulation of programmed cell death GO:0043068 218 0.011
monosaccharide metabolic process GO:0005996 106 0.011
cognition GO:0050890 149 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
regulation of leukocyte mediated immunity GO:0002703 104 0.011
striated muscle tissue development GO:0014706 293 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
anatomical structure homeostasis GO:0060249 145 0.011
heterocycle catabolic process GO:0046700 280 0.011
glucose transport GO:0015758 56 0.011
vesicle localization GO:0051648 86 0.011
limb development GO:0060173 166 0.011
organophosphate biosynthetic process GO:0090407 122 0.011
response to acid chemical GO:0001101 111 0.011
regulation of response to wounding GO:1903034 189 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of anatomical structure size GO:0090066 178 0.011
limb morphogenesis GO:0035108 149 0.011
actin cytoskeleton organization GO:0030036 220 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
dna recombination GO:0006310 92 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
urogenital system development GO:0001655 261 0.011
response to peptide GO:1901652 136 0.010
response to peptide hormone GO:0043434 127 0.010
maintenance of location GO:0051235 89 0.010
purine ribonucleotide catabolic process GO:0009154 208 0.010
histone methylation GO:0016571 71 0.010
i kappab kinase nf kappab signaling GO:0007249 85 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.010
glucose metabolic process GO:0006006 92 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
phospholipid metabolic process GO:0006644 87 0.010
calcium ion homeostasis GO:0055074 127 0.010
response to radiation GO:0009314 165 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
negative regulation of organelle organization GO:0010639 90 0.010
regulation of ossification GO:0030278 112 0.010
purine containing compound catabolic process GO:0072523 213 0.010
stem cell differentiation GO:0048863 268 0.010
Worm
response to lipopolysaccharide GO:0032496 128 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
transmission of nerve impulse GO:0019226 76 0.010
gene silencing by rna GO:0031047 19 0.010
positive regulation of proteolysis GO:0045862 85 0.010
cell chemotaxis GO:0060326 81 0.010
lateral inhibition GO:0046331 1 0.010
action potential GO:0001508 78 0.010
regulation of protein binding GO:0043393 60 0.010
immune response regulating signaling pathway GO:0002764 125 0.010
myeloid cell differentiation GO:0030099 233 0.010
embryonic genitalia morphogenesis GO:0030538 4 0.010
negative regulation of cell activation GO:0050866 111 0.010

Brdt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.012
neurodegenerative disease DOID:1289 0 0.011