Mus musculus

0 known processes

Adam12

a disintegrin and metallopeptidase domain 12 (meltrin alpha)

(Aliases: mKIAA4001,Mltna,KIAA4001)

Adam12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of eosinophil migration GO:2000418 2 0.950
Mouse
regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000307 1 0.946
Mouse
regulation of inflammatory response GO:0050727 147 0.929
Mouse
extracellular matrix dependent thymocyte migration GO:0072680 1 0.896
Mouse
positive regulation of tumor necrosis factor ligand superfamily member 11 production GO:2000309 1 0.879
Mouse
thymocyte migration GO:0072679 2 0.857
Mouse
fibronectin dependent thymocyte migration GO:0072681 1 0.754
Mouse
regulation of protein kinase activity GO:0045859 232 0.699
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.660
Mouse
regulation of defense response GO:0031347 233 0.644
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.643
Mouse
protein kinase b signaling GO:0043491 74 0.625
Mouse
positive regulation of innate immune response GO:0045089 80 0.622
Mouse
prevention of polyspermy GO:0060468 4 0.615
Mouse
positive regulation of response to wounding GO:1903036 66 0.611
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.591
Mouse
regulation of fibronectin dependent thymocyte migration GO:2000413 1 0.590
Mouse
negative regulation of reproductive process GO:2000242 31 0.574
Mouse
regulation of thymocyte migration GO:2000410 2 0.547
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.535
Mouse
positive regulation of kinase activity GO:0033674 155 0.531
Mouse
activation of immune response GO:0002253 138 0.518
Mouse
sensory organ morphogenesis GO:0090596 242 0.504
neuron apoptotic process GO:0051402 142 0.502
Mouse
positive regulation of inflammatory response GO:0050729 47 0.490
Mouse
regulation of acute inflammatory response GO:0002673 27 0.483
Mouse
regulation of eosinophil migration GO:2000416 2 0.480
Mouse
forebrain development GO:0030900 302 0.477
leukocyte differentiation GO:0002521 342 0.475
Mouse
myelination in peripheral nervous system GO:0022011 19 0.458
Mouse
neuron death GO:0070997 154 0.457
Mouse
regulation of response to wounding GO:1903034 189 0.454
Mouse
stem cell development GO:0048864 219 0.451
Mouse
cytokine production GO:0001816 319 0.451
Mouse
peripheral nervous system development GO:0007422 53 0.450
Mouse
inflammatory response GO:0006954 244 0.439
Mouse
positive regulation of homeostatic process GO:0032846 64 0.437
Mouse
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.433
Mouse
t cell apoptotic process GO:0070231 39 0.429
Mouse
regulation of cytokine production GO:0001817 266 0.417
Mouse
regulation of cell motility GO:2000145 236 0.403
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.401
urogenital system development GO:0001655 261 0.395
regulation of proteolysis GO:0030162 164 0.395
Mouse
positive regulation of apoptotic process GO:0043065 217 0.394
Mouse
activation of innate immune response GO:0002218 56 0.394
Mouse
gliogenesis GO:0042063 141 0.387
Mouse
multicellular organismal homeostasis GO:0048871 164 0.377
Mouse
chemotaxis GO:0006935 247 0.375
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.374
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.370
Mouse
extracellular structure organization GO:0043062 148 0.369
spleen development GO:0048536 39 0.367
Mouse
regulation of mapk cascade GO:0043408 248 0.360
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.358
Mouse
innate immune response GO:0045087 157 0.355
Mouse
anatomical structure homeostasis GO:0060249 145 0.354
Mouse
t cell activation GO:0042110 289 0.354
Mouse
positive regulation of fibronectin dependent thymocyte migration GO:2000415 1 0.353
Mouse
leukocyte migration involved in inflammatory response GO:0002523 7 0.350
Mouse
single organism cell adhesion GO:0098602 156 0.329
Mouse
response to growth factor GO:0070848 198 0.329
Mouse
extracellular matrix organization GO:0030198 147 0.328
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.318
Mouse
cell adhesion GO:0007155 329 0.312
Mouse
positive regulation of thymocyte migration GO:2000412 2 0.307
Mouse
positive regulation of cell death GO:0010942 224 0.307
Mouse
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.303
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.292
positive regulation of protein modification process GO:0031401 299 0.292
Mouse
blood vessel morphogenesis GO:0048514 285 0.289
Mouse
regulation of kinase activity GO:0043549 249 0.289
Mouse
positive regulation of acute inflammatory response GO:0002675 16 0.284
Mouse
positive regulation of t cell differentiation in thymus GO:0033089 13 0.284
Mouse
immune response activating signal transduction GO:0002757 116 0.284
Mouse
positive regulation of transferase activity GO:0051347 167 0.283
Mouse
regulation of bone remodeling GO:0046850 28 0.278
Mouse
activation of mapk activity GO:0000187 59 0.278
Mouse
lymphocyte apoptotic process GO:0070227 54 0.273
Mouse
mapk cascade GO:0000165 281 0.272
Mouse
regulation of lymphocyte apoptotic process GO:0070228 41 0.272
Mouse
response to organonitrogen compound GO:0010243 246 0.269
skeletal system development GO:0001501 356 0.269
axonogenesis GO:0007409 274 0.265
positive regulation of proteolysis GO:0045862 85 0.262
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.259
Mouse
bone remodeling GO:0046849 53 0.258
Mouse
innate immune response activating signal transduction GO:0002758 50 0.255
Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.254
Mouse
negative regulation of fertilization GO:0060467 5 0.245
Mouse
locomotory behavior GO:0007626 195 0.242
Mouse
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.241
Mouse
acute inflammatory response GO:0002526 41 0.241
Mouse
regulation of t cell differentiation in thymus GO:0033081 24 0.236
Mouse
visual learning GO:0008542 44 0.234
Mouse
axon guidance GO:0007411 141 0.233
mesenchymal cell differentiation GO:0048762 107 0.232
Mouse
lymphocyte differentiation GO:0030098 242 0.225
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.224
Mouse
tumor necrosis factor ligand superfamily member 11 production GO:0072535 1 0.221
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.220
Mouse
regulation of t cell activation GO:0050863 170 0.219
Mouse
regulation of map kinase activity GO:0043405 120 0.217
Mouse
t cell differentiation in thymus GO:0033077 77 0.210
Mouse
eosinophil migration GO:0072677 3 0.208
Mouse
regulation of cell activation GO:0050865 289 0.204
Mouse
associative learning GO:0008306 61 0.204
Mouse
thymocyte apoptotic process GO:0070242 19 0.203
Mouse
negative regulation of multi organism process GO:0043901 68 0.203
Mouse
regulation of reproductive process GO:2000241 66 0.201
Mouse
mesenchymal cell development GO:0014031 93 0.197
Mouse
cognition GO:0050890 149 0.195
Mouse
b cell differentiation GO:0030183 78 0.193
Mouse
negative regulation of neuron death GO:1901215 98 0.193
Mouse
epithelial to mesenchymal transition GO:0001837 47 0.191
Mouse
negative regulation of growth GO:0045926 99 0.190
regulation of cell migration GO:0030334 219 0.190
Mouse
positive regulation of programmed cell death GO:0043068 218 0.188
Mouse
regulation of homeostatic process GO:0032844 182 0.188
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.185
Mouse
tissue remodeling GO:0048771 102 0.184
Mouse
telencephalon development GO:0021537 186 0.182
regulation of cellular ketone metabolic process GO:0010565 66 0.181
regulation of thymocyte apoptotic process GO:0070243 14 0.178
Mouse
heart morphogenesis GO:0003007 178 0.177
Mouse
immune effector process GO:0002252 321 0.176
learning GO:0007612 98 0.170
Mouse
positive regulation of mapk cascade GO:0043410 170 0.169
Mouse
regulation of multi organism process GO:0043900 111 0.167
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.165
cellular amine metabolic process GO:0044106 44 0.164
regulation of cellular amine metabolic process GO:0033238 20 0.163
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.162
Mouse
leukocyte migration GO:0050900 124 0.160
Mouse
visual behavior GO:0007632 45 0.159
Mouse
mesenchyme development GO:0060485 152 0.159
Mouse
regulation of transferase activity GO:0051338 263 0.159
Mouse
glial cell differentiation GO:0010001 131 0.159
Mouse
cell matrix adhesion GO:0007160 68 0.159
kidney epithelium development GO:0072073 121 0.159
membrane protein proteolysis GO:0033619 10 0.157
Mouse
bone resorption GO:0045453 38 0.155
Mouse
cartilage development GO:0051216 140 0.154
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.154
stem cell differentiation GO:0048863 268 0.151
Mouse
regulation of secretion GO:0051046 274 0.150
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.150
Mouse
regulation of neuron death GO:1901214 134 0.149
Mouse
positive regulation of defense response GO:0031349 124 0.149
Mouse
cell type specific apoptotic process GO:0097285 268 0.146
Mouse
tissue homeostasis GO:0001894 115 0.146
Mouse
negative regulation of cell substrate adhesion GO:0010812 16 0.146
regulation of innate immune response GO:0045088 91 0.145
Mouse
response to corticosteroid GO:0031960 20 0.143
Mouse
sperm egg recognition GO:0035036 37 0.143
Mouse
central nervous system neuron axonogenesis GO:0021955 28 0.142
regulation of tissue remodeling GO:0034103 38 0.142
Mouse
skin development GO:0043588 220 0.141
response to radiation GO:0009314 165 0.137
Mouse
leukocyte chemotaxis GO:0030595 69 0.136
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.135
Mouse
single fertilization GO:0007338 82 0.135
Mouse
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.135
Mouse
pallium development GO:0021543 120 0.134
cell substrate adhesion GO:0031589 130 0.130
regulation of mast cell apoptotic process GO:0033025 5 0.129
Mouse
t cell differentiation GO:0030217 174 0.126
Mouse
cellular ketone metabolic process GO:0042180 84 0.126
positive regulation of bone resorption GO:0045780 13 0.124
Mouse
protein processing GO:0016485 163 0.123
collagen fibril organization GO:0030199 32 0.123
response to light stimulus GO:0009416 135 0.123
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.122
actin cytoskeleton organization GO:0030036 220 0.122
spermatogenesis GO:0007283 284 0.122
positive regulation of lymphocyte activation GO:0051251 140 0.121
Mouse
cell chemotaxis GO:0060326 81 0.120
Mouse
synaptic transmission GO:0007268 329 0.120
regulation of t cell differentiation GO:0045580 83 0.119
Mouse
leukocyte homeostasis GO:0001776 79 0.117
Mouse
positive regulation of cytokine production GO:0001819 174 0.117
Mouse
myeloid cell apoptotic process GO:0033028 22 0.116
Mouse
positive regulation of cell development GO:0010720 237 0.114
cellular response to cytokine stimulus GO:0071345 189 0.113
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.112
Mouse
renal system development GO:0072001 225 0.110
cell cell recognition GO:0009988 44 0.110
Mouse
protein maturation GO:0051604 176 0.110
branching morphogenesis of an epithelial tube GO:0048754 159 0.108
positive regulation of cell migration GO:0030335 109 0.107
Mouse
limb development GO:0060173 166 0.105
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.103
Mouse
learning or memory GO:0007611 148 0.100
Mouse
skeletal system morphogenesis GO:0048705 203 0.100
response to transforming growth factor beta GO:0071559 88 0.100
Mouse
regulation of establishment of protein localization GO:0070201 181 0.099
positive regulation of secretion by cell GO:1903532 114 0.097
gland development GO:0048732 330 0.095
regulation of cell projection organization GO:0031344 206 0.094
chondrocyte development GO:0002063 24 0.092
morphogenesis of a branching epithelium GO:0061138 193 0.092
organelle localization GO:0051640 179 0.091
positive regulation of cell adhesion GO:0045785 80 0.091
Mouse
mast cell apoptotic process GO:0033024 5 0.091
Mouse
limb morphogenesis GO:0035108 149 0.090
regulation of lymphocyte differentiation GO:0045619 107 0.089
Mouse
adaptive immune response GO:0002250 155 0.088
Mouse
neuron migration GO:0001764 122 0.087
positive regulation of t cell apoptotic process GO:0070234 8 0.087
Mouse
ras protein signal transduction GO:0007265 77 0.087
germinal center formation GO:0002467 16 0.087
Mouse
regionalization GO:0003002 337 0.086
positive regulation of nervous system development GO:0051962 221 0.086
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.085
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.085
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.083
Mouse
cellular homeostasis GO:0019725 240 0.083
schwann cell development GO:0014044 22 0.082
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.082
transmission of nerve impulse GO:0019226 76 0.082
Mouse
wound healing GO:0042060 157 0.082
regulation of secretion by cell GO:1903530 249 0.079
positive regulation of bone remodeling GO:0046852 13 0.079
Mouse
negative regulation of cell adhesion GO:0007162 45 0.079
retina morphogenesis in camera type eye GO:0060042 45 0.078
regulation of bone resorption GO:0045124 24 0.077
Mouse
regulation of membrane potential GO:0042391 192 0.077
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.077
central nervous system neuron development GO:0021954 67 0.076
positive regulation of leukocyte apoptotic process GO:2000108 21 0.076
Mouse
regulation of anatomical structure size GO:0090066 178 0.075
positive regulation of leukocyte differentiation GO:1902107 86 0.075
Mouse
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.073
Mouse
amine metabolic process GO:0009308 45 0.073
regulation of system process GO:0044057 200 0.073
activation of mapk activity involved in innate immune response GO:0035419 2 0.073
Mouse
positive regulation of cell motility GO:2000147 116 0.072
Mouse
appendage morphogenesis GO:0035107 149 0.072
epithelial tube morphogenesis GO:0060562 303 0.071
regulation of cell adhesion GO:0030155 154 0.070
Mouse
kidney development GO:0001822 213 0.070
fertilization GO:0009566 127 0.070
Mouse
positive regulation of protein catabolic process GO:0045732 60 0.070
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.070
cellular response to lipid GO:0071396 145 0.069
ureteric bud development GO:0001657 94 0.069
myelination GO:0042552 74 0.069
Mouse
angiogenesis GO:0001525 201 0.069
Mouse
male gamete generation GO:0048232 285 0.068
positive regulation of tissue remodeling GO:0034105 19 0.068
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.068
immune response regulating signaling pathway GO:0002764 125 0.067
Mouse
cellular amino acid metabolic process GO:0006520 103 0.067
macromolecule catabolic process GO:0009057 281 0.067
Mouse
positive regulation of thymocyte apoptotic process GO:0070245 5 0.065
Mouse
single organismal cell cell adhesion GO:0016337 131 0.065
Mouse
schwann cell differentiation GO:0014037 26 0.065
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.064
maintenance of location GO:0051235 89 0.064
positive regulation of cell activation GO:0050867 158 0.063
Mouse
organophosphate catabolic process GO:0046434 232 0.063
negative regulation of protein metabolic process GO:0051248 282 0.062
response to extracellular stimulus GO:0009991 127 0.062
negative regulation of intracellular signal transduction GO:1902532 167 0.062
adult behavior GO:0030534 135 0.061
Mouse
response to lipopolysaccharide GO:0032496 128 0.061
negative regulation of phosphorus metabolic process GO:0010563 184 0.061
multicellular organismal signaling GO:0035637 91 0.061
Mouse
blood circulation GO:0008015 195 0.060
response to acid chemical GO:0001101 111 0.060
regulation of rho protein signal transduction GO:0035023 71 0.060
negative regulation of molecular function GO:0044092 258 0.060
tissue migration GO:0090130 68 0.060
regulation of protein catabolic process GO:0042176 108 0.060
Mouse
regulation of protein kinase b signaling GO:0051896 56 0.059
Mouse
negative regulation of phospholipase activity GO:0010519 4 0.059
neuronal action potential GO:0019228 54 0.059
Mouse
action potential GO:0001508 78 0.059
Mouse
sensory perception GO:0007600 245 0.059
morphogenesis of a branching structure GO:0001763 203 0.057
appendage development GO:0048736 166 0.057
regulation of neuron projection development GO:0010975 169 0.057
positive regulation of lymphocyte differentiation GO:0045621 61 0.057
Mouse
leukocyte apoptotic process GO:0071887 71 0.057
Mouse
negative regulation of nervous system development GO:0051961 156 0.056
rac protein signal transduction GO:0016601 13 0.056
regulation of protein localization GO:0032880 231 0.056
smooth muscle contraction GO:0006939 44 0.056
positive regulation of t cell activation GO:0050870 101 0.056
Mouse
cell growth GO:0016049 130 0.055
positive regulation of lymphocyte migration GO:2000403 11 0.055
Mouse
chondrocyte differentiation GO:0002062 72 0.055
central nervous system projection neuron axonogenesis GO:0021952 21 0.055
regulation of ossification GO:0030278 112 0.055
epidermis development GO:0008544 187 0.055
positive regulation of protein kinase b signaling GO:0051897 32 0.055
Mouse
protein catabolic process GO:0030163 221 0.055
Mouse
regulation of t cell apoptotic process GO:0070232 28 0.055
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.054
head morphogenesis GO:0060323 34 0.054
negative regulation of cell proliferation GO:0008285 296 0.054
mast cell homeostasis GO:0033023 5 0.053
Mouse
apoptotic signaling pathway GO:0097190 306 0.053
b cell activation GO:0042113 161 0.052
Mouse
positive regulation of rho gtpase activity GO:0032321 41 0.052
regulation of epidermal cell differentiation GO:0045604 21 0.052
endochondral bone morphogenesis GO:0060350 50 0.052
rap protein signal transduction GO:0032486 3 0.051
positive regulation of secretion GO:0051047 130 0.051
cellular response to acid chemical GO:0071229 68 0.051
digestive system development GO:0055123 200 0.051
response to organic cyclic compound GO:0014070 198 0.051
Mouse
purine nucleotide metabolic process GO:0006163 302 0.049
glial cell development GO:0021782 54 0.048
Mouse
negative regulation of cell motility GO:2000146 61 0.048
cellular chemical homeostasis GO:0055082 215 0.048
negative regulation of cellular amine metabolic process GO:0033239 1 0.048
bone development GO:0060348 120 0.048
cellular extravasation GO:0045123 17 0.047
Mouse
rhythmic process GO:0048511 174 0.047
negative regulation of neuron projection regeneration GO:0070571 3 0.047
cellular response to hormone stimulus GO:0032870 150 0.046
developmental maturation GO:0021700 193 0.046
negative regulation of cell migration GO:0030336 59 0.046
positive regulation of neuron differentiation GO:0045666 141 0.046
peptidyl tyrosine modification GO:0018212 145 0.046
reactive oxygen species biosynthetic process GO:1903409 8 0.046
egg activation GO:0007343 7 0.045
Mouse
ear morphogenesis GO:0042471 118 0.045
organonitrogen compound biosynthetic process GO:1901566 192 0.044
positive regulation of neuron projection regeneration GO:0070572 2 0.044
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.044
Mouse
jnk cascade GO:0007254 72 0.044
regulation of stress activated mapk cascade GO:0032872 69 0.044
cell recognition GO:0008037 83 0.044
Mouse
regulation of blood vessel size GO:0050880 56 0.043
lymphocyte migration GO:0072676 26 0.043
Mouse
epithelial cell development GO:0002064 159 0.043
optic nerve development GO:0021554 8 0.043
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
regulation of intracellular transport GO:0032386 159 0.042
detection of abiotic stimulus GO:0009582 60 0.042
nucleotide metabolic process GO:0009117 332 0.041
circulatory system process GO:0003013 197 0.041
regulation of cellular catabolic process GO:0031329 242 0.041
Mouse
ameboidal type cell migration GO:0001667 128 0.041
gastrulation GO:0007369 116 0.041
body morphogenesis GO:0010171 45 0.041
positive regulation of neuron projection development GO:0010976 79 0.041
regulation of protein transport GO:0051223 163 0.040
positive regulation of stress activated mapk cascade GO:0032874 48 0.040
regulation of lymphocyte activation GO:0051249 240 0.040
Mouse
lens development in camera type eye GO:0002088 62 0.040
stress activated protein kinase signaling cascade GO:0031098 81 0.040
positive regulation of map kinase activity GO:0043406 84 0.040
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.040
negative regulation of protein phosphorylation GO:0001933 126 0.040
transmembrane transport GO:0055085 412 0.040
negative regulation of phosphorylation GO:0042326 166 0.039
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.039
Mouse
detection of external stimulus GO:0009581 61 0.039
regulation of angiogenesis GO:0045765 81 0.039
response to molecule of bacterial origin GO:0002237 143 0.039
regulation of cell growth GO:0001558 91 0.039
glucose homeostasis GO:0042593 128 0.039
regeneration GO:0031099 38 0.038
cardiac epithelial to mesenchymal transition GO:0060317 18 0.038
Mouse
retina development in camera type eye GO:0060041 119 0.038
spermatid development GO:0007286 108 0.038
axon ensheathment GO:0008366 76 0.038
Mouse
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.038
Mouse
regulation of heart contraction GO:0008016 77 0.038
nucleoside phosphate metabolic process GO:0006753 338 0.037
response to steroid hormone GO:0048545 56 0.036
Mouse
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.036
detection of stimulus GO:0051606 84 0.035
cellular response to amino acid stimulus GO:0071230 29 0.035
photoreceptor cell development GO:0042461 40 0.035
hormone secretion GO:0046879 128 0.035
respiratory tube development GO:0030323 167 0.035
aorta smooth muscle tissue morphogenesis GO:0060414 2 0.035
nucleoside metabolic process GO:0009116 246 0.035
embryonic organ morphogenesis GO:0048562 276 0.035
digestive tract development GO:0048565 190 0.035
rho protein signal transduction GO:0007266 32 0.035
forebrain cell migration GO:0021885 58 0.035
embryonic epithelial tube formation GO:0001838 130 0.034
cellular response to lipopolysaccharide GO:0071222 77 0.033
protein oligomerization GO:0051259 67 0.033
gtp catabolic process GO:0006184 143 0.033
substrate dependent cell migration GO:0006929 18 0.033
Mouse
binding of sperm to zona pellucida GO:0007339 34 0.033
Mouse
response to monosaccharide GO:0034284 67 0.033
germ cell development GO:0007281 185 0.032
regulation of organelle organization GO:0033043 289 0.032
negative regulation of cell growth GO:0030308 44 0.032
stress activated mapk cascade GO:0051403 80 0.032
myeloid cell differentiation GO:0030099 233 0.032
connective tissue development GO:0061448 179 0.032
intracellular protein transport GO:0006886 204 0.032
myeloid leukocyte activation GO:0002274 83 0.032
hindbrain development GO:0030902 128 0.032
g protein coupled receptor signaling pathway GO:0007186 243 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
endocrine process GO:0050886 39 0.031
protein heterotrimerization GO:0070208 8 0.031
positive regulation of camp mediated signaling GO:0043950 3 0.031
glycoprotein metabolic process GO:0009100 116 0.031
positive regulation of jnk cascade GO:0046330 46 0.031
hindbrain tangential cell migration GO:0021934 2 0.031
ensheathment of neurons GO:0007272 76 0.031
Mouse
development of primary sexual characteristics GO:0045137 143 0.031
positive regulation of t cell migration GO:2000406 10 0.031
Mouse
regulation of hormone levels GO:0010817 211 0.031
response to temperature stimulus GO:0009266 55 0.030
cranial nerve development GO:0021545 41 0.030
response to drug GO:0042493 75 0.030
Mouse
cellular response to external stimulus GO:0071496 88 0.030
peptidyl amino acid modification GO:0018193 336 0.030
peptide transport GO:0015833 133 0.030
cellular response to molecule of bacterial origin GO:0071219 83 0.030
lymphocyte activation involved in immune response GO:0002285 93 0.030
neural tube development GO:0021915 160 0.030
syncytium formation by plasma membrane fusion GO:0000768 42 0.029
response to peptide hormone GO:0043434 127 0.029
negative regulation of synapse assembly GO:0051964 3 0.029
semaphorin plexin signaling pathway GO:0071526 21 0.029
homeostasis of number of cells GO:0048872 210 0.029
Mouse
cell activation involved in immune response GO:0002263 126 0.029
positive regulation of intracellular transport GO:0032388 70 0.029
skeletal muscle organ development GO:0060538 163 0.029
cerebral cortex development GO:0021987 86 0.029
regulation of cellular response to stress GO:0080135 159 0.029
organic cyclic compound catabolic process GO:1901361 295 0.029
regulation of neuron migration GO:2001222 22 0.029
cell maturation GO:0048469 127 0.029
carbohydrate metabolic process GO:0005975 230 0.029
smooth muscle tissue development GO:0048745 22 0.029
fibril organization GO:0097435 2 0.029
ventral spinal cord development GO:0021517 48 0.029
synapse assembly GO:0007416 56 0.028
neuron projection extension GO:1990138 64 0.028
motor neuron axon guidance GO:0008045 26 0.028
phosphatidylinositol mediated signaling GO:0048015 41 0.028
ribonucleoside triphosphate catabolic process GO:0009203 199 0.028
regulation of protein secretion GO:0050708 82 0.028
protein heterooligomerization GO:0051291 14 0.028
peptidyl tyrosine phosphorylation GO:0018108 143 0.027
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.027
nitrogen compound transport GO:0071705 271 0.027
gonad development GO:0008406 141 0.027
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.027
purine containing compound metabolic process GO:0072521 311 0.027
adult locomotory behavior GO:0008344 91 0.027
Mouse
neuron projection guidance GO:0097485 141 0.027
negative regulation of response to wounding GO:1903035 77 0.027
regulation of epithelial cell migration GO:0010632 35 0.027
embryonic skeletal system morphogenesis GO:0048704 91 0.027
astrocyte fate commitment GO:0060018 4 0.026
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.026
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.026
organonitrogen compound catabolic process GO:1901565 264 0.026
regulation of ras gtpase activity GO:0032318 88 0.026
negative regulation of cytokine production GO:0001818 84 0.026
negative regulation of endothelial cell migration GO:0010596 4 0.026
carbohydrate derivative catabolic process GO:1901136 231 0.026
proteoglycan biosynthetic process GO:0030166 20 0.026
nephron development GO:0072006 109 0.026
bone morphogenesis GO:0060349 78 0.025
protein secretion GO:0009306 111 0.025
alpha beta t cell activation GO:0046631 91 0.025
protein localization to organelle GO:0033365 185 0.025
renal tubule morphogenesis GO:0061333 72 0.025
membrane organization GO:0061024 245 0.025
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.025
Mouse
cellular response to hexose stimulus GO:0071331 47 0.025
regulation of body fluid levels GO:0050878 162 0.025
cd4 positive alpha beta t cell activation GO:0035710 45 0.025
ossification GO:0001503 216 0.025
face morphogenesis GO:0060325 29 0.025
blood vessel endothelial cell migration GO:0043534 23 0.024
response to glucocorticoid GO:0051384 20 0.024
Mouse
negative regulation of t cell activation GO:0050868 65 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.024
placenta development GO:0001890 140 0.024
regulation of binding GO:0051098 111 0.024
striated muscle tissue development GO:0014706 293 0.024
ribose phosphate metabolic process GO:0019693 291 0.023
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.023
defense response to other organism GO:0098542 197 0.023
regulation of hydrolase activity GO:0051336 246 0.023
regulation of jnk cascade GO:0046328 62 0.023

Adam12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.280
musculoskeletal system disease DOID:17 0 0.280
muscular disease DOID:0080000 0 0.037
connective tissue disease DOID:65 0 0.023