Mus musculus

0 known processes

Adam1b

a disintegrin and metallopeptidase domain 1b

(Aliases: Ftna,Adam1)

Adam1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of lymphocyte activation GO:0051249 240 0.127
Mouse
cation transport GO:0006812 399 0.118
positive regulation of dopamine secretion GO:0033603 2 0.108
regulation of response to wounding GO:1903034 189 0.100
Mouse
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.100
regulation of defense response GO:0031347 233 0.094
Mouse
eosinophil migration GO:0072677 3 0.093
Mouse
organic anion transport GO:0015711 137 0.080
cellular amino acid metabolic process GO:0006520 103 0.077
sensory perception GO:0007600 245 0.076
neuron death GO:0070997 154 0.075
Mouse
response to radiation GO:0009314 165 0.068
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.063
cellular homeostasis GO:0019725 240 0.062
calcium ion transport GO:0006816 159 0.062
regulation of cell activation GO:0050865 289 0.061
Mouse
cellular response to hormone stimulus GO:0032870 150 0.058
male gamete generation GO:0048232 285 0.056
sensory perception of light stimulus GO:0050953 54 0.055
macromolecule catabolic process GO:0009057 281 0.055
Mouse
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.055
transmembrane transport GO:0055085 412 0.055
regulation of secretion GO:0051046 274 0.054
neurotransmitter transport GO:0006836 76 0.054
inflammatory response GO:0006954 244 0.053
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.052
regulation of cellular amino acid metabolic process GO:0006521 5 0.051
cation transmembrane transport GO:0098655 266 0.050
lymphocyte proliferation GO:0046651 164 0.050
cell recognition GO:0008037 83 0.049
Mouse
carbohydrate metabolic process GO:0005975 230 0.048
cellular ketone metabolic process GO:0042180 84 0.048
cellular response to organonitrogen compound GO:0071417 145 0.047
positive regulation of catecholamine secretion GO:0033605 2 0.047
leukocyte migration GO:0050900 124 0.046
Mouse
single fertilization GO:0007338 82 0.046
Mouse
positive regulation of kinase activity GO:0033674 155 0.045
Mouse
regulation of transferase activity GO:0051338 263 0.044
Mouse
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.043
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.042
Mouse
cell cell recognition GO:0009988 44 0.042
Mouse
cellular amine metabolic process GO:0044106 44 0.042
positive regulation of transferase activity GO:0051347 167 0.041
Mouse
leukocyte chemotaxis GO:0030595 69 0.039
Mouse
positive regulation of cell development GO:0010720 237 0.038
response to lipopolysaccharide GO:0032496 128 0.037
neurotransmitter secretion GO:0007269 62 0.037
amine metabolic process GO:0009308 45 0.037
regulation of protein kinase activity GO:0045859 232 0.036
Mouse
purine containing compound catabolic process GO:0072523 213 0.036
circadian sleep wake cycle rem sleep GO:0042747 1 0.036
synaptic transmission involved in micturition GO:0060084 3 0.036
peptidyl amino acid modification GO:0018193 336 0.036
binding of sperm to zona pellucida GO:0007339 34 0.035
Mouse
regulation of ion transport GO:0043269 215 0.035
sequestering of metal ion GO:0051238 19 0.035
negative regulation of phosphorus metabolic process GO:0010563 184 0.034
positive regulation of cell motility GO:2000147 116 0.034
Mouse
acetylcholine transport GO:0015870 2 0.034
cellular chemical homeostasis GO:0055082 215 0.033
acetylcholine secretion neurotransmission GO:0014055 2 0.033
cell chemotaxis GO:0060326 81 0.033
Mouse
acetate ester transport GO:1901374 2 0.032
adult behavior GO:0030534 135 0.032
Mouse
protein catabolic process GO:0030163 221 0.032
Mouse
leukocyte mediated immunity GO:0002443 174 0.032
blood circulation GO:0008015 195 0.031
protein maturation GO:0051604 176 0.030
digestive tract development GO:0048565 190 0.030
cellular response to molecule of bacterial origin GO:0071219 83 0.030
regulation of hydrolase activity GO:0051336 246 0.030
b cell activation GO:0042113 161 0.029
Mouse
maintenance of location GO:0051235 89 0.029
regulation of leukocyte proliferation GO:0070663 121 0.029
small gtpase mediated signal transduction GO:0007264 97 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
positive regulation of lymphocyte activation GO:0051251 140 0.029
Mouse
immune effector process GO:0002252 321 0.028
response to light stimulus GO:0009416 135 0.028
Mouse
divalent inorganic cation transport GO:0072511 178 0.028
multicellular organism growth GO:0035264 161 0.028
striated muscle tissue development GO:0014706 293 0.028
lateral geniculate nucleus development GO:0021771 1 0.027
action potential GO:0001508 78 0.027
Mouse
leukocyte proliferation GO:0070661 172 0.027
protein modification by small protein conjugation or removal GO:0070647 207 0.027
regulation of neuron differentiation GO:0045664 281 0.027
foregut regionalization GO:0060423 3 0.026
cellular divalent inorganic cation homeostasis GO:0072503 127 0.026
cellular protein complex assembly GO:0043623 116 0.026
development of primary male sexual characteristics GO:0046546 88 0.025
membrane organization GO:0061024 245 0.025
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.025
negative regulation of molecular function GO:0044092 258 0.025
regulation of ketone biosynthetic process GO:0010566 2 0.025
regulation of vesicle mediated transport GO:0060627 139 0.025
skeletal system development GO:0001501 356 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
regulation of neurotransmitter levels GO:0001505 87 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.024
carboxylic acid transport GO:0046942 100 0.024
cell growth GO:0016049 130 0.024
ion transmembrane transport GO:0034220 361 0.024
regulation of lymphocyte differentiation GO:0045619 107 0.024
Mouse
adult locomotory behavior GO:0008344 91 0.024
Mouse
positive regulation of programmed cell death GO:0043068 218 0.023
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.023
Mouse
single organism cell adhesion GO:0098602 156 0.023
Mouse
oxygen homeostasis GO:0032364 2 0.023
cation homeostasis GO:0055080 212 0.023
visual perception GO:0007601 52 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.023
Mouse
regulation of actin filament based process GO:0032970 99 0.023
response to organic cyclic compound GO:0014070 198 0.023
Mouse
camera type eye development GO:0043010 266 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
dendrite development GO:0016358 115 0.023
negative regulation of intracellular signal transduction GO:1902532 167 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
Mouse
cellular response to biotic stimulus GO:0071216 92 0.022
sensory organ morphogenesis GO:0090596 242 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
generation of ovulation cycle rhythm GO:0060112 1 0.022
regulation of testosterone biosynthetic process GO:2000224 2 0.022
protein processing GO:0016485 163 0.022
positive regulation of proteolysis GO:0045862 85 0.022
Mouse
positive regulation of leukocyte proliferation GO:0070665 73 0.022
positive regulation of apoptotic process GO:0043065 217 0.021
Mouse
muscle system process GO:0003012 141 0.021
negative regulation of response to wounding GO:1903035 77 0.021
circulatory system process GO:0003013 197 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.021
Mouse
response to nutrient levels GO:0031667 109 0.021
regulation of circadian sleep wake cycle non rem sleep GO:0045188 1 0.021
regulation of t cell activation GO:0050863 170 0.021
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.021
regulation of inflammatory response GO:0050727 147 0.021
Mouse
response to organonitrogen compound GO:0010243 246 0.021
detection of abiotic stimulus GO:0009582 60 0.021
detection of stimulus involved in sensory perception GO:0050906 44 0.021
lymphocyte mediated immunity GO:0002449 139 0.021
negative regulation of protein modification process GO:0031400 163 0.020
divalent metal ion transport GO:0070838 172 0.020
organic hydroxy compound metabolic process GO:1901615 203 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
organonitrogen compound catabolic process GO:1901565 264 0.020
regulation of nucleotide metabolic process GO:0006140 169 0.020
developmental cell growth GO:0048588 84 0.020
oxidation reduction process GO:0055114 342 0.020
regulation of lipid metabolic process GO:0019216 118 0.020
positive regulation of cellular amine metabolic process GO:0033240 5 0.020
retina development in camera type eye GO:0060041 119 0.020
negative regulation of immune system process GO:0002683 209 0.020
aromatic compound catabolic process GO:0019439 286 0.019
retina morphogenesis in camera type eye GO:0060042 45 0.019
regulation of organelle organization GO:0033043 289 0.019
somatotropin secreting cell differentiation GO:0060126 4 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
cellular response to peptide hormone stimulus GO:0071375 92 0.019
cytosolic calcium ion transport GO:0060401 48 0.019
protein modification by small protein conjugation GO:0032446 187 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
cellular response to lipid GO:0071396 145 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
leukocyte differentiation GO:0002521 342 0.019
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.019
regulation of epithelial cell proliferation GO:0050678 141 0.019
organic acid transport GO:0015849 101 0.019
regulation of cell cycle GO:0051726 281 0.019
neural retina development GO:0003407 41 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
adult walking behavior GO:0007628 41 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
regulation of circadian rhythm GO:0042752 58 0.018
sequestering of calcium ion GO:0051208 18 0.018
t cell differentiation GO:0030217 174 0.018
Mouse
mitotic cell cycle GO:0000278 195 0.018
response to extracellular stimulus GO:0009991 127 0.018
norepinephrine transport GO:0015874 2 0.018
peptidyl serine modification GO:0018209 83 0.018
b cell mediated immunity GO:0019724 71 0.017
multi multicellular organism process GO:0044706 109 0.017
negative regulation of defense response GO:0031348 77 0.017
metal ion homeostasis GO:0055065 189 0.017
steroid metabolic process GO:0008202 119 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.017
vascular process in circulatory system GO:0003018 62 0.017
regulation of leukocyte mediated immunity GO:0002703 104 0.017
neuron apoptotic process GO:0051402 142 0.017
Mouse
regulation of cellular catabolic process GO:0031329 242 0.017
Mouse
ras protein signal transduction GO:0007265 77 0.017
regulation of leukocyte apoptotic process GO:2000106 56 0.017
Mouse
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.017
cellular lipid metabolic process GO:0044255 323 0.017
heart contraction GO:0060047 93 0.017
male sex differentiation GO:0046661 109 0.017
positive regulation of atpase activity GO:0032781 3 0.017
posttranscriptional regulation of gene expression GO:0010608 155 0.017
skeletal system morphogenesis GO:0048705 203 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
Mouse
sperm egg recognition GO:0035036 37 0.016
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
angiogenesis GO:0001525 201 0.016
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.016
regulation of anatomical structure size GO:0090066 178 0.016
small molecule catabolic process GO:0044282 71 0.016
stem cell development GO:0048864 219 0.016
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.016
purine containing compound metabolic process GO:0072521 311 0.016
cytokine production GO:0001816 319 0.016
Mouse
cognition GO:0050890 149 0.016
Mouse
positive regulation of cytokine production GO:0001819 174 0.016
Mouse
fertilization GO:0009566 127 0.016
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
mitotic cell cycle process GO:1903047 159 0.016
calcium ion homeostasis GO:0055074 127 0.016
positive regulation of cell activation GO:0050867 158 0.015
Mouse
cellular response to peptide GO:1901653 92 0.015
muscle contraction GO:0006936 101 0.015
regulation of ossification GO:0030278 112 0.015
regulation of transforming growth factor beta2 production GO:0032909 2 0.015
immune response regulating signaling pathway GO:0002764 125 0.015
Mouse
ribonucleoside metabolic process GO:0009119 245 0.015
regulation of vasculature development GO:1901342 88 0.015
circadian sleep wake cycle non rem sleep GO:0042748 2 0.015
sensory perception of taste GO:0050909 18 0.015
nucleoside catabolic process GO:0009164 206 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
carbohydrate homeostasis GO:0033500 128 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.015
Mouse
positive regulation of t cell activation GO:0050870 101 0.015
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.015
norepinephrine secretion GO:0048243 2 0.015
cellular response to carbohydrate stimulus GO:0071322 50 0.015
lymphocyte differentiation GO:0030098 242 0.015
Mouse
interferon gamma production GO:0032609 67 0.015
mammary gland bud formation GO:0060615 2 0.015
positive regulation of inflammatory response GO:0050729 47 0.015
Mouse
t cell activation GO:0042110 289 0.015
Mouse
midgut development GO:0007494 4 0.015
negative regulation of action potential GO:0045759 1 0.015
organic hydroxy compound transport GO:0015850 93 0.015
ribose phosphate metabolic process GO:0019693 291 0.014
response to inorganic substance GO:0010035 96 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
regulation of system process GO:0044057 200 0.014
peptidyl tyrosine modification GO:0018212 145 0.014
circadian rhythm GO:0007623 114 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
Mouse
translation GO:0006412 93 0.014
regulation of cellular component size GO:0032535 121 0.014
protein ubiquitination GO:0016567 171 0.014
nitrogen compound transport GO:0071705 271 0.014
regulation of secretion by cell GO:1903530 249 0.014
epithelial cell proliferation GO:0050673 174 0.014
sulfur compound metabolic process GO:0006790 100 0.014
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.014
ameboidal type cell migration GO:0001667 128 0.014
endomembrane system organization GO:0010256 147 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
apoptotic signaling pathway GO:0097190 306 0.014
positive regulation of response to wounding GO:1903036 66 0.014
Mouse
rhythmic process GO:0048511 174 0.014
regulation of proteolysis GO:0030162 164 0.014
Mouse
response to pain GO:0048265 26 0.014
tissue migration GO:0090130 68 0.014
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.014
Mouse
protein secretion GO:0009306 111 0.014
exocytosis GO:0006887 121 0.013
nucleotide metabolic process GO:0009117 332 0.013
positive regulation of protein modification process GO:0031401 299 0.013
Mouse
b cell proliferation GO:0042100 53 0.013
learning GO:0007612 98 0.013
Mouse
germ cell development GO:0007281 185 0.013
regulation of cell projection organization GO:0031344 206 0.013
neural tube development GO:0021915 160 0.013
glycoprotein metabolic process GO:0009100 116 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
activation of immune response GO:0002253 138 0.013
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
response to monosaccharide GO:0034284 67 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
positive regulation of t cell differentiation GO:0045582 52 0.013
Mouse
positive regulation of lymphocyte apoptotic process GO:0070230 13 0.013
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.013
purine nucleoside catabolic process GO:0006152 205 0.013
regulation of norepinephrine secretion GO:0014061 2 0.013
release of sequestered calcium ion into cytosol GO:0051209 42 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
male gonad development GO:0008584 88 0.012
regulation of membrane potential GO:0042391 192 0.012
Mouse
prostate gland development GO:0030850 48 0.012
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.012
regulation of cell motility GO:2000145 236 0.012
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
sperm motility GO:0030317 47 0.012
cellular calcium ion homeostasis GO:0006874 119 0.012
extracellular structure organization GO:0043062 148 0.012
epithelial cell migration GO:0010631 63 0.012
regulation of interleukin 6 production GO:0032675 55 0.012
response to peptide GO:1901652 136 0.012
muscle tissue development GO:0060537 308 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
regulation of interferon gamma production GO:0032649 57 0.012
amine transport GO:0015837 21 0.012
glucose homeostasis GO:0042593 128 0.012
regulation of apoptotic signaling pathway GO:2001233 197 0.012
positive regulation of lymphocyte differentiation GO:0045621 61 0.012
Mouse
glucose metabolic process GO:0006006 92 0.012
regulation of cell migration GO:0030334 219 0.012
Mouse
stem cell maintenance GO:0019827 130 0.012
cell type specific apoptotic process GO:0097285 268 0.012
Mouse
vesicle organization GO:0016050 60 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of embryonic development GO:0045995 71 0.012
anion transmembrane transport GO:0098656 71 0.012
cellular response to monosaccharide stimulus GO:0071326 47 0.012
positive regulation of lymphocyte proliferation GO:0050671 70 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
rho protein signal transduction GO:0007266 32 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
positive regulation of protein transport GO:0051222 93 0.011
cellular response to lipopolysaccharide GO:0071222 77 0.011
t cell proliferation GO:0042098 120 0.011
regulation of cell growth GO:0001558 91 0.011
multicellular organismal signaling GO:0035637 91 0.011
Mouse
positive regulation of growth GO:0045927 104 0.011
regulation of t cell differentiation GO:0045580 83 0.011
Mouse
cerebellum morphogenesis GO:0021587 42 0.011
cytosolic calcium ion homeostasis GO:0051480 70 0.011
innate immune response GO:0045087 157 0.011
Mouse
protein targeting GO:0006605 143 0.011
detection of stimulus GO:0051606 84 0.011
transmission of nerve impulse GO:0019226 76 0.011
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.011
organophosphate catabolic process GO:0046434 232 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
positive regulation of nervous system development GO:0051962 221 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
regulation of neuron projection development GO:0010975 169 0.011
branching morphogenesis of an epithelial tube GO:0048754 159 0.011
pma inducible membrane protein ectodomain proteolysis GO:0051088 1 0.011
Mouse
homeostasis of number of cells GO:0048872 210 0.011
Mouse
cytoplasmic transport GO:0016482 234 0.011
plasma membrane organization GO:0007009 90 0.011
immune response activating signal transduction GO:0002757 116 0.011
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.011
Mouse
nucleoside metabolic process GO:0009116 246 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
connective tissue development GO:0061448 179 0.011
ensheathment of neurons GO:0007272 76 0.011
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.011
neural tube patterning GO:0021532 43 0.011
adaptive immune response GO:0002250 155 0.011
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.011
negative regulation of phosphorylation GO:0042326 166 0.011
dephosphorylation GO:0016311 129 0.010
negative regulation of androgen biosynthetic process GO:2000180 1 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
pallium development GO:0021543 120 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
positive regulation of peptidase activity GO:0010952 49 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
visual learning GO:0008542 44 0.010
Mouse
cellular protein catabolic process GO:0044257 155 0.010
peptide metabolic process GO:0006518 46 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.010
Mouse
cervix development GO:0060067 2 0.010
regulation of circadian sleep wake cycle GO:0042749 3 0.010
regulation of cellular response to stress GO:0080135 159 0.010
oviduct development GO:0060066 3 0.010
monocarboxylic acid transport GO:0015718 44 0.010
heart process GO:0003015 94 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
neural tube formation GO:0001841 108 0.010
fibroblast growth factor production GO:0090269 4 0.010
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.010
cellular response to glucose stimulus GO:0071333 45 0.010

Adam1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
nervous system disease DOID:863 0 0.072
disease of metabolism DOID:0014667 0 0.018