Mus musculus

0 known processes

Pnpla1

patatin-like phospholipase domain containing 1

Pnpla1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
skin development GO:0043588 220 0.059
cation transport GO:0006812 399 0.058
cellular amino acid metabolic process GO:0006520 103 0.057
camera type eye development GO:0043010 266 0.056
leukocyte differentiation GO:0002521 342 0.055
organonitrogen compound biosynthetic process GO:1901566 192 0.054
nucleoside phosphate metabolic process GO:0006753 338 0.052
purine nucleotide metabolic process GO:0006163 302 0.051
cellular ketone metabolic process GO:0042180 84 0.049
sensory perception GO:0007600 245 0.049
organophosphate catabolic process GO:0046434 232 0.048
organic hydroxy compound metabolic process GO:1901615 203 0.046
epithelial cell development GO:0002064 159 0.044
organic cyclic compound catabolic process GO:1901361 295 0.044
cellular amine metabolic process GO:0044106 44 0.043
ribonucleotide metabolic process GO:0009259 291 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
protein maturation GO:0051604 176 0.039
purine containing compound metabolic process GO:0072521 311 0.038
heterocycle catabolic process GO:0046700 280 0.038
amine metabolic process GO:0009308 45 0.037
divalent inorganic cation transport GO:0072511 178 0.036
purine nucleoside metabolic process GO:0042278 241 0.035
monocarboxylic acid metabolic process GO:0032787 191 0.035
cellular lipid metabolic process GO:0044255 323 0.034
Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.033
apoptotic signaling pathway GO:0097190 306 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
aromatic compound catabolic process GO:0019439 286 0.031
lymphocyte differentiation GO:0030098 242 0.031
fatty acid metabolic process GO:0006631 121 0.031
regulation of cell cycle GO:0051726 281 0.031
regulation of interleukin 8 production GO:0032677 3 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
nucleobase containing small molecule metabolic process GO:0055086 352 0.030
regulation of cellular amine metabolic process GO:0033238 20 0.030
developmental maturation GO:0021700 193 0.030
regulation of interleukin 8 secretion GO:2000482 2 0.030
immune effector process GO:0002252 321 0.030
nucleoside triphosphate metabolic process GO:0009141 230 0.029
regulation of protein localization GO:0032880 231 0.029
interleukin 8 production GO:0032637 4 0.029
cell maturation GO:0048469 127 0.029
ribonucleoside metabolic process GO:0009119 245 0.028
response to acid chemical GO:0001101 111 0.028
carbohydrate metabolic process GO:0005975 230 0.028
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
alcohol metabolic process GO:0006066 116 0.027
regulation of body fluid levels GO:0050878 162 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
calcium ion transport GO:0006816 159 0.026
multicellular organismal signaling GO:0035637 91 0.026
g protein coupled receptor signaling pathway GO:0007186 243 0.026
kidney development GO:0001822 213 0.025
nucleoside catabolic process GO:0009164 206 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
macromolecule catabolic process GO:0009057 281 0.025
protein processing GO:0016485 163 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
small molecule biosynthetic process GO:0044283 132 0.025
negative regulation of molecular function GO:0044092 258 0.024
wound healing GO:0042060 157 0.024
wnt signaling pathway GO:0016055 188 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
phospholipid metabolic process GO:0006644 87 0.024
nucleotide metabolic process GO:0009117 332 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
ribonucleoside triphosphate metabolic process GO:0009199 220 0.023
response to organic cyclic compound GO:0014070 198 0.023
ribose phosphate metabolic process GO:0019693 291 0.022
synaptic transmission GO:0007268 329 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
cytoplasmic transport GO:0016482 234 0.022
calcium ion transmembrane transport GO:0070588 85 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
nucleoside metabolic process GO:0009116 246 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
ribonucleoside catabolic process GO:0042454 206 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.021
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
organonitrogen compound catabolic process GO:1901565 264 0.021
interleukin 8 secretion GO:0072606 3 0.021
epithelial cell proliferation GO:0050673 174 0.021
regionalization GO:0003002 337 0.021
divalent metal ion transport GO:0070838 172 0.021
sequestering of metal ion GO:0051238 19 0.021
regulation of hydrolase activity GO:0051336 246 0.021
regulation of defense response GO:0031347 233 0.021
cellular nitrogen compound catabolic process GO:0044270 280 0.021
purine nucleoside catabolic process GO:0006152 205 0.020
divalent inorganic cation homeostasis GO:0072507 138 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
spermatogenesis GO:0007283 284 0.019
protein catabolic process GO:0030163 221 0.019
positive regulation of programmed cell death GO:0043068 218 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.019
sequestering of calcium ion GO:0051208 18 0.019
epidermis development GO:0008544 187 0.019
negative regulation of cellular component organization GO:0051129 194 0.019
lung development GO:0030324 164 0.019
negative regulation of cell proliferation GO:0008285 296 0.018
microtubule based process GO:0007017 236 0.018
sulfur compound metabolic process GO:0006790 100 0.018
embryonic placenta development GO:0001892 98 0.018
organophosphate biosynthetic process GO:0090407 122 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
mapk cascade GO:0000165 281 0.018
ear development GO:0043583 200 0.018
cation transmembrane transport GO:0098655 266 0.018
nucleoside phosphate catabolic process GO:1901292 222 0.018
digestive tract development GO:0048565 190 0.017
positive regulation of hydrolase activity GO:0051345 148 0.017
gland development GO:0048732 330 0.017
nucleotide catabolic process GO:0009166 217 0.017
cellular alcohol biosynthetic process GO:0044108 3 0.017
urogenital system development GO:0001655 261 0.017
regulation of antimicrobial humoral response GO:0002759 3 0.017
axonogenesis GO:0007409 274 0.017
renal system development GO:0072001 225 0.017
endocytosis GO:0006897 168 0.017
nucleoside monophosphate metabolic process GO:0009123 85 0.017
regulation of organelle organization GO:0033043 289 0.017
inflammatory response GO:0006954 244 0.017
glycerophospholipid metabolic process GO:0006650 71 0.017
peptidyl tyrosine phosphorylation GO:0018108 143 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
hematopoietic progenitor cell differentiation GO:0002244 143 0.016
positive regulation of apoptotic process GO:0043065 217 0.016
regulation of ion transport GO:0043269 215 0.016
respiratory system development GO:0060541 190 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
muscle tissue development GO:0060537 308 0.016
regulation of secretion GO:0051046 274 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
cell fate commitment GO:0045165 210 0.016
forebrain development GO:0030900 302 0.016
regulation of neuron differentiation GO:0045664 281 0.016
dna metabolic process GO:0006259 303 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
male gamete generation GO:0048232 285 0.016
cellular homeostasis GO:0019725 240 0.016
membrane organization GO:0061024 245 0.016
placenta development GO:0001890 140 0.016
regulation of lipid metabolic process GO:0019216 118 0.015
transmission of nerve impulse GO:0019226 76 0.015
digestive system development GO:0055123 200 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
skeletal muscle cell differentiation GO:0035914 66 0.015
ion transmembrane transport GO:0034220 361 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
lipid catabolic process GO:0016042 69 0.015
Fly
epithalamus development GO:0021538 2 0.015
maintenance of location GO:0051235 89 0.015
Fly
nuclear division GO:0000280 158 0.015
nuclear transport GO:0051169 139 0.015
regulation of lymphocyte activation GO:0051249 240 0.015
intracellular protein transport GO:0006886 204 0.015
skeletal muscle organ development GO:0060538 163 0.015
negative regulation of protein metabolic process GO:0051248 282 0.015
regulation of cellular catabolic process GO:0031329 242 0.015
glycoprotein metabolic process GO:0009100 116 0.015
endomembrane system organization GO:0010256 147 0.015
fat soluble vitamin biosynthetic process GO:0042362 4 0.015
response to organonitrogen compound GO:0010243 246 0.015
positive regulation of cell death GO:0010942 224 0.014
engulfment of apoptotic cell GO:0043652 3 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
glycosyl compound catabolic process GO:1901658 206 0.014
spermatid development GO:0007286 108 0.014
morphogenesis of a branching structure GO:0001763 203 0.014
regulation of metal ion transport GO:0010959 106 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
organelle fission GO:0048285 170 0.014
purine containing compound catabolic process GO:0072523 213 0.014
positive regulation of protein modification process GO:0031401 299 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
embryonic skeletal system development GO:0048706 120 0.014
regulation of transferase activity GO:0051338 263 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
nephron epithelium development GO:0072009 92 0.014
lipid biosynthetic process GO:0008610 179 0.013
cellular ion homeostasis GO:0006873 165 0.013
regulation of response to wounding GO:1903034 189 0.013
regulation of cell migration GO:0030334 219 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
carboxylic acid transport GO:0046942 100 0.013
innate immune response GO:0045087 157 0.013
cellular macromolecule catabolic process GO:0044265 206 0.013
positive regulation of interleukin 8 production GO:0032757 2 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
central nervous system neuron differentiation GO:0021953 162 0.013
biomineral tissue development GO:0031214 64 0.013
negative regulation of nervous system development GO:0051961 156 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.013
compound eye development GO:0048749 1 0.013
regulation of protein transport GO:0051223 163 0.013
metal ion homeostasis GO:0055065 189 0.012
cell type specific apoptotic process GO:0097285 268 0.012
negative regulation of defense response GO:0031348 77 0.012
spermatid differentiation GO:0048515 115 0.012
transmembrane transport GO:0055085 412 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
regulation of secretion by cell GO:1903530 249 0.012
rhythmic process GO:0048511 174 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
regulation of epithelial cell proliferation GO:0050678 141 0.012
positive regulation of nucleoside metabolic process GO:0045979 91 0.012
protein localization to membrane GO:0072657 108 0.012
cilium morphogenesis GO:0060271 102 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of cellular ketone metabolic process GO:0010565 66 0.012
atp metabolic process GO:0046034 75 0.012
alcohol biosynthetic process GO:0046165 43 0.012
t cell activation GO:0042110 289 0.012
development of primary sexual characteristics GO:0045137 143 0.012
regulation of cell activation GO:0050865 289 0.012
nitrogen compound transport GO:0071705 271 0.012
regulation of mapk cascade GO:0043408 248 0.012
skeletal system development GO:0001501 356 0.012
intermediate filament based process GO:0045103 27 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
steroid metabolic process GO:0008202 119 0.012
cation homeostasis GO:0055080 212 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of proteolysis GO:0030162 164 0.012
cytokine production GO:0001816 319 0.012
regulation of feeding behavior GO:0060259 3 0.012
cellular response to lipid GO:0071396 145 0.012
mitotic cell cycle GO:0000278 195 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
regulation of retina development in camera type eye GO:1902866 3 0.011
vitamin d biosynthetic process GO:0042368 3 0.011
negative regulation of response to wounding GO:1903035 77 0.011
fertilization GO:0009566 127 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
positive regulation of nucleotide metabolic process GO:0045981 114 0.011
cellular response to acid chemical GO:0071229 68 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.011
stem cell maintenance GO:0019827 130 0.011
lens development in camera type eye GO:0002088 62 0.011
mesodermal cell migration GO:0008078 4 0.011
germ cell development GO:0007281 185 0.011
cell adhesion GO:0007155 329 0.011
protein localization to nucleus GO:0034504 121 0.011
regulation of antimicrobial peptide production GO:0002784 1 0.011
mitotic cell cycle process GO:1903047 159 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
hormone secretion GO:0046879 128 0.011
tube formation GO:0035148 140 0.011
homeostasis of number of cells GO:0048872 210 0.011
carbohydrate homeostasis GO:0033500 128 0.011
lipid localization GO:0010876 126 0.011
Fly
peptidyl amino acid modification GO:0018193 336 0.011
nuclear import GO:0051170 95 0.011
anatomical structure homeostasis GO:0060249 145 0.011
neural tube formation GO:0001841 108 0.011
respiratory tube development GO:0030323 167 0.011
canonical wnt signaling pathway GO:0060070 130 0.011
organic acid biosynthetic process GO:0016053 86 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
tissue homeostasis GO:0001894 115 0.011
regulation of cytokine production GO:0001817 266 0.010
antimicrobial peptide biosynthetic process GO:0002777 2 0.010
response to light stimulus GO:0009416 135 0.010
regulation of protein kinase activity GO:0045859 232 0.010
keratinocyte differentiation GO:0030216 48 0.010
midbrain hindbrain boundary maturation GO:0021732 1 0.010
regulation of homeostatic process GO:0032844 182 0.010
regulation of peptidase activity GO:0052547 96 0.010
ras protein signal transduction GO:0007265 77 0.010
organic acid transport GO:0015849 101 0.010
telencephalon development GO:0021537 186 0.010
blood circulation GO:0008015 195 0.010
calcium ion homeostasis GO:0055074 127 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
anion transport GO:0006820 177 0.010
regulation of calcium ion transport GO:0051924 69 0.010
cellular protein catabolic process GO:0044257 155 0.010
positive regulation of organelle organization GO:0010638 128 0.010
t cell differentiation GO:0030217 174 0.010
regulation of protein catabolic process GO:0042176 108 0.010
positive regulation of ion transport GO:0043270 65 0.010
pharynx development GO:0060465 1 0.010
blood vessel morphogenesis GO:0048514 285 0.010
cellular calcium ion homeostasis GO:0006874 119 0.010
regulation of engulfment of apoptotic cell GO:1901074 2 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010

Pnpla1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
connective tissue disease DOID:65 0 0.026
musculoskeletal system disease DOID:17 0 0.026
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.011