Mus musculus

71 known processes

Pank1

pantothenate kinase 1

(Aliases: 4632412I06Rik,Pank1b,5430426F23Rik,Pank1a,Pank,panK1beta)

Pank1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.109
cellular ketone metabolic process GO:0042180 84 0.101
regulation of cellular ketone metabolic process GO:0010565 66 0.078
oxidation reduction process GO:0055114 342 0.072
Mouse
amine metabolic process GO:0009308 45 0.068
cellular lipid metabolic process GO:0044255 323 0.067
cellular amine metabolic process GO:0044106 44 0.064
regulation of cellular amino acid metabolic process GO:0006521 5 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.057
nucleoside phosphate metabolic process GO:0006753 338 0.053
lipid biosynthetic process GO:0008610 179 0.046
organonitrogen compound catabolic process GO:1901565 264 0.042
ribonucleoside metabolic process GO:0009119 245 0.042
purine containing compound metabolic process GO:0072521 311 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
fatty acid metabolic process GO:0006631 121 0.038
heterocycle catabolic process GO:0046700 280 0.038
peptidyl amino acid modification GO:0018193 336 0.037
purine ribonucleoside metabolic process GO:0046128 241 0.037
purine nucleotide metabolic process GO:0006163 302 0.037
carboxylic acid biosynthetic process GO:0046394 86 0.036
nucleotide metabolic process GO:0009117 332 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.036
nucleobase containing small molecule metabolic process GO:0055086 352 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
response to organonitrogen compound GO:0010243 246 0.033
organic cyclic compound catabolic process GO:1901361 295 0.033
glycosyl compound metabolic process GO:1901657 246 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
purine nucleoside metabolic process GO:0042278 241 0.031
small gtpase mediated signal transduction GO:0007264 97 0.030
nucleoside metabolic process GO:0009116 246 0.030
cofactor metabolic process GO:0051186 80 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
monocarboxylic acid metabolic process GO:0032787 191 0.029
small molecule biosynthetic process GO:0044283 132 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.028
regulation of organelle organization GO:0033043 289 0.027
aromatic compound catabolic process GO:0019439 286 0.027
regulation of membrane potential GO:0042391 192 0.027
Mouse
organonitrogen compound biosynthetic process GO:1901566 192 0.027
transmembrane transport GO:0055085 412 0.027
regulation of cellular catabolic process GO:0031329 242 0.027
small molecule catabolic process GO:0044282 71 0.026
gland development GO:0048732 330 0.026
ribonucleotide metabolic process GO:0009259 291 0.025
cellular response to organonitrogen compound GO:0071417 145 0.025
rho protein signal transduction GO:0007266 32 0.025
dna metabolic process GO:0006259 303 0.025
ribonucleoside triphosphate metabolic process GO:0009199 220 0.025
organic acid catabolic process GO:0016054 51 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
ras protein signal transduction GO:0007265 77 0.024
membrane organization GO:0061024 245 0.024
Fly
male gamete generation GO:0048232 285 0.024
Mouse Fly
organic acid biosynthetic process GO:0016053 86 0.024
organic hydroxy compound metabolic process GO:1901615 203 0.023
organophosphate catabolic process GO:0046434 232 0.023
spermatogenesis GO:0007283 284 0.023
Mouse Fly
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
carboxylic acid catabolic process GO:0046395 51 0.022
cation transport GO:0006812 399 0.022
purine containing compound catabolic process GO:0072523 213 0.022
multicellular organismal signaling GO:0035637 91 0.022
nitrogen compound transport GO:0071705 271 0.022
alpha amino acid metabolic process GO:1901605 59 0.022
cellular homeostasis GO:0019725 240 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
chromatin modification GO:0016568 187 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.021
apoptotic signaling pathway GO:0097190 306 0.021
macromolecule catabolic process GO:0009057 281 0.021
mapk cascade GO:0000165 281 0.021
transmission of nerve impulse GO:0019226 76 0.020
organelle fission GO:0048285 170 0.020
Fly
cytoplasmic transport GO:0016482 234 0.020
negative regulation of cellular amine metabolic process GO:0033239 1 0.020
response to nutrient levels GO:0031667 109 0.020
positive regulation of cell death GO:0010942 224 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
maintenance of location GO:0051235 89 0.020
nuclear division GO:0000280 158 0.020
Fly
nucleotide catabolic process GO:0009166 217 0.020
carbohydrate derivative biosynthetic process GO:1901137 183 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
anion transport GO:0006820 177 0.019
epithelial cell development GO:0002064 159 0.019
carbohydrate derivative catabolic process GO:1901136 231 0.019
response to extracellular stimulus GO:0009991 127 0.019
negative regulation of molecular function GO:0044092 258 0.019
regulation of lipid metabolic process GO:0019216 118 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
cellular response to lipid GO:0071396 145 0.019
carbohydrate metabolic process GO:0005975 230 0.019
action potential GO:0001508 78 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
regulation of cell activation GO:0050865 289 0.019
fatty acid biosynthetic process GO:0006633 41 0.019
innate immune response GO:0045087 157 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
nucleoside catabolic process GO:0009164 206 0.018
sensory perception GO:0007600 245 0.018
positive regulation of protein modification process GO:0031401 299 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
renal system development GO:0072001 225 0.018
ribonucleoside catabolic process GO:0042454 206 0.018
regulation of hydrolase activity GO:0051336 246 0.018
lipid catabolic process GO:0016042 69 0.018
purine ribonucleotide catabolic process GO:0009154 208 0.018
myeloid cell differentiation GO:0030099 233 0.018
ribonucleoside triphosphate catabolic process GO:0009203 199 0.018
monocarboxylic acid biosynthetic process GO:0072330 61 0.018
cytokine production GO:0001816 319 0.018
protein catabolic process GO:0030163 221 0.017
positive regulation of cell development GO:0010720 237 0.017
chromatin organization GO:0006325 206 0.017
response to organic cyclic compound GO:0014070 198 0.017
regulation of cytokine production GO:0001817 266 0.017
coenzyme metabolic process GO:0006732 52 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of homeostatic process GO:0032844 182 0.017
negative regulation of phosphate metabolic process GO:0045936 184 0.017
ion transmembrane transport GO:0034220 361 0.017
negative regulation of cellular component organization GO:0051129 194 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
germ cell development GO:0007281 185 0.017
Mouse Fly
regulation of secretion by cell GO:1903530 249 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
cellular lipid catabolic process GO:0044242 52 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of transferase activity GO:0051338 263 0.016
generation of precursor metabolites and energy GO:0006091 103 0.016
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
regulation of secretion GO:0051046 274 0.016
immune effector process GO:0002252 321 0.016
protein ubiquitination GO:0016567 171 0.016
regulation of kinase activity GO:0043549 249 0.016
muscle tissue development GO:0060537 308 0.016
protein modification by small protein conjugation or removal GO:0070647 207 0.016
histone modification GO:0016570 159 0.016
regulation of mapk cascade GO:0043408 248 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
regulation of protein kinase activity GO:0045859 232 0.015
fat cell differentiation GO:0045444 160 0.015
meiotic cell cycle GO:0051321 122 0.015
Fly
organic acid transport GO:0015849 101 0.015
cation transmembrane transport GO:0098655 266 0.015
cell type specific apoptotic process GO:0097285 268 0.015
glycerolipid metabolic process GO:0046486 122 0.015
regulation of neuron differentiation GO:0045664 281 0.015
synaptic transmission GO:0007268 329 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
methylation GO:0032259 134 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
energy derivation by oxidation of organic compounds GO:0015980 77 0.015
Mouse
axonogenesis GO:0007409 274 0.015
spermatid differentiation GO:0048515 115 0.015
Mouse
response to acid chemical GO:0001101 111 0.015
skin development GO:0043588 220 0.015
negative regulation of immune system process GO:0002683 209 0.014
skeletal system development GO:0001501 356 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
regulation of cell cycle GO:0051726 281 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
urogenital system development GO:0001655 261 0.014
blood vessel morphogenesis GO:0048514 285 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
positive regulation of programmed cell death GO:0043068 218 0.014
forebrain development GO:0030900 302 0.014
chemotaxis GO:0006935 247 0.014
neuronal action potential GO:0019228 54 0.014
muscle cell differentiation GO:0042692 261 0.014
camera type eye development GO:0043010 266 0.014
striated muscle tissue development GO:0014706 293 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
protein localization to organelle GO:0033365 185 0.014
carbohydrate homeostasis GO:0033500 128 0.014
rhythmic process GO:0048511 174 0.014
Fly
acylglycerol metabolic process GO:0006639 55 0.014
locomotory behavior GO:0007626 195 0.014
Fly
protein maturation GO:0051604 176 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
hematopoietic progenitor cell differentiation GO:0002244 143 0.014
regulation of cell motility GO:2000145 236 0.014
organic anion transport GO:0015711 137 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
meiotic nuclear division GO:0007126 115 0.013
Fly
regulation of intracellular transport GO:0032386 159 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
regulation of hormone levels GO:0010817 211 0.013
leukocyte differentiation GO:0002521 342 0.013
multicellular organism growth GO:0035264 161 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
heart morphogenesis GO:0003007 178 0.013
dephosphorylation GO:0016311 129 0.013
endomembrane system organization GO:0010256 147 0.013
covalent chromatin modification GO:0016569 163 0.013
negative regulation of protein modification process GO:0031400 163 0.013
cellular carbohydrate metabolic process GO:0044262 119 0.013
sulfur compound metabolic process GO:0006790 100 0.013
blood circulation GO:0008015 195 0.013
regulation of anatomical structure size GO:0090066 178 0.013
spermatid development GO:0007286 108 0.013
Mouse
muscle system process GO:0003012 141 0.013
macromolecule methylation GO:0043414 120 0.013
developmental maturation GO:0021700 193 0.013
cellular alcohol biosynthetic process GO:0044108 3 0.013
translation GO:0006412 93 0.013
protein processing GO:0016485 163 0.013
regulation of cell projection organization GO:0031344 206 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
organelle localization GO:0051640 179 0.013
tissue homeostasis GO:0001894 115 0.013
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
response to peptide GO:1901652 136 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
adult behavior GO:0030534 135 0.012
response to inorganic substance GO:0010035 96 0.012
homeostasis of number of cells GO:0048872 210 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of ion transport GO:0043269 215 0.012
endocytosis GO:0006897 168 0.012
kidney development GO:0001822 213 0.012
telencephalon development GO:0021537 186 0.012
cellular protein complex assembly GO:0043623 116 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
circadian rhythm GO:0007623 114 0.012
Fly
cellular response to biotic stimulus GO:0071216 92 0.012
negative regulation of phosphorylation GO:0042326 166 0.012
positive regulation of protein kinase activity GO:0045860 144 0.012
regulation of cell cycle process GO:0010564 160 0.012
regulation of system process GO:0044057 200 0.012
sequestering of calcium ion GO:0051208 18 0.012
positive regulation of apoptotic process GO:0043065 217 0.012
regulation of binding GO:0051098 111 0.012
microtubule based process GO:0007017 236 0.012
intracellular protein transport GO:0006886 204 0.012
ossification GO:0001503 216 0.012
steroid metabolic process GO:0008202 119 0.012
response to oxidative stress GO:0006979 123 0.012
Fly
response to peptide hormone GO:0043434 127 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
cellular ion homeostasis GO:0006873 165 0.012
anatomical structure homeostasis GO:0060249 145 0.012
lateral inhibition GO:0046331 1 0.012
positive regulation of hydrolase activity GO:0051345 148 0.012
amide transport GO:0042886 138 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
positive regulation of organelle organization GO:0010638 128 0.012
cation homeostasis GO:0055080 212 0.012
response to growth factor GO:0070848 198 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
response to molecule of bacterial origin GO:0002237 143 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
actin cytoskeleton organization GO:0030036 220 0.011
positive regulation of kinase activity GO:0033674 155 0.011
divalent metal ion transport GO:0070838 172 0.011
sensory organ morphogenesis GO:0090596 242 0.011
lipid localization GO:0010876 126 0.011
peptide transport GO:0015833 133 0.011
nuclear transport GO:0051169 139 0.011
cellular alcohol metabolic process GO:0044107 3 0.011
mitotic cell cycle GO:0000278 195 0.011
Fly
morphogenesis of a branching structure GO:0001763 203 0.011
regulation of carbohydrate metabolic process GO:0006109 75 0.011
positive regulation of transferase activity GO:0051347 167 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
regulation of response to wounding GO:1903034 189 0.011
cell adhesion GO:0007155 329 0.011
glucose homeostasis GO:0042593 128 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
connective tissue development GO:0061448 179 0.011
olfactory learning GO:0008355 2 0.011
mitotic cell cycle process GO:1903047 159 0.011
Fly
cell activation involved in immune response GO:0002263 126 0.011
t cell activation GO:0042110 289 0.011
protein targeting GO:0006605 143 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
respiratory system development GO:0060541 190 0.011
alcohol metabolic process GO:0006066 116 0.011
regulation of feeding behavior GO:0060259 3 0.011
cellular response to peptide GO:1901653 92 0.011
lipid transport GO:0006869 98 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
mitochondrion organization GO:0007005 134 0.011
Mouse
respiratory tube development GO:0030323 167 0.011
regulation of multi organism process GO:0043900 111 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
response to insulin GO:0032868 100 0.011
coenzyme biosynthetic process GO:0009108 23 0.011
neuron death GO:0070997 154 0.011
cellular amino acid catabolic process GO:0009063 25 0.011
embryonic organ morphogenesis GO:0048562 276 0.011
response to lipopolysaccharide GO:0032496 128 0.011
lymphocyte differentiation GO:0030098 242 0.011
regulation of cellular response to stress GO:0080135 159 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
thioester metabolic process GO:0035383 19 0.010
sulfur compound biosynthetic process GO:0044272 37 0.010
atp metabolic process GO:0046034 75 0.010
lung development GO:0030324 164 0.010
development of primary sexual characteristics GO:0045137 143 0.010
cellular response to acid chemical GO:0071229 68 0.010
cellular response to molecule of bacterial origin GO:0071219 83 0.010
ensheathment of neurons GO:0007272 76 0.010
regulation of neuron projection development GO:0010975 169 0.010
myeloid leukocyte differentiation GO:0002573 119 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.010
muscle contraction GO:0006936 101 0.010
negative regulation of cell cycle GO:0045786 123 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
inorganic ion transmembrane transport GO:0098660 234 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
monosaccharide metabolic process GO:0005996 106 0.010
regulation of protein transport GO:0051223 163 0.010
protein acylation GO:0043543 64 0.010
stem cell differentiation GO:0048863 268 0.010
epidermis development GO:0008544 187 0.010

Pank1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.032
amino acid metabolic disorder DOID:9252 0 0.023
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of cellular proliferation DOID:14566 0 0.014
central nervous system disease DOID:331 0 0.014
cancer DOID:162 0 0.012
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
musculoskeletal system disease DOID:17 0 0.011
organ system cancer DOID:0050686 0 0.011
neurodegenerative disease DOID:1289 0 0.010