Mus musculus

68 known processes

Htra1

HtrA serine peptidase 1

(Aliases: Prss11,AI429470,RSPP11,L56,HTRA)

Htra1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to growth factor GO:0070848 198 0.421
chemotaxis GO:0006935 247 0.356
extracellular structure organization GO:0043062 148 0.355
negative regulation of cell proliferation GO:0008285 296 0.213
regulation of cell motility GO:2000145 236 0.191
response to radiation GO:0009314 165 0.185
cellular response to growth factor stimulus GO:0071363 197 0.176
bone development GO:0060348 120 0.162
angiogenesis GO:0001525 201 0.156
morphogenesis of a branching structure GO:0001763 203 0.150
ossification GO:0001503 216 0.141
regulation of angiogenesis GO:0045765 81 0.136
extracellular matrix organization GO:0030198 147 0.134
epithelial tube morphogenesis GO:0060562 303 0.125
response to light stimulus GO:0009416 135 0.117
regulation of proteolysis GO:0030162 164 0.116
Fly
response to organonitrogen compound GO:0010243 246 0.113
positive regulation of cellular amine metabolic process GO:0033240 5 0.113
amine metabolic process GO:0009308 45 0.111
gland development GO:0048732 330 0.109
blood vessel morphogenesis GO:0048514 285 0.109
lung development GO:0030324 164 0.103
positive regulation of protein modification process GO:0031401 299 0.102
neuron projection guidance GO:0097485 141 0.101
muscle cell differentiation GO:0042692 261 0.099
axonogenesis GO:0007409 274 0.098
ameboidal type cell migration GO:0001667 128 0.094
cellular ketone metabolic process GO:0042180 84 0.094
branching involved in salivary gland morphogenesis GO:0060445 26 0.090
skeletal muscle organ development GO:0060538 163 0.088
mapk cascade GO:0000165 281 0.084
anatomical structure homeostasis GO:0060249 145 0.083
response to oxidative stress GO:0006979 123 0.083
positive regulation of protein phosphorylation GO:0001934 242 0.082
regulation of transferase activity GO:0051338 263 0.082
cellular amino acid metabolic process GO:0006520 103 0.080
axon guidance GO:0007411 141 0.080
regulation of vasculature development GO:1901342 88 0.080
cell substrate adhesion GO:0031589 130 0.076
muscle tissue development GO:0060537 308 0.076
response to transforming growth factor beta GO:0071559 88 0.076
positive regulation of cell death GO:0010942 224 0.075
Mouse Fly
negative regulation of protein metabolic process GO:0051248 282 0.074
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.073
Zebrafish
cell matrix adhesion GO:0007160 68 0.072
camera type eye development GO:0043010 266 0.072
embryonic organ morphogenesis GO:0048562 276 0.071
respiratory tube development GO:0030323 167 0.070
regulation of cell adhesion GO:0030155 154 0.070
regulation of mapk cascade GO:0043408 248 0.067
skeletal system development GO:0001501 356 0.066
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.066
regulation of hydrolase activity GO:0051336 246 0.065
Fly
cellular amine metabolic process GO:0044106 44 0.065
protein catabolic process GO:0030163 221 0.064
positive regulation of cell motility GO:2000147 116 0.064
regulation of cell migration GO:0030334 219 0.063
transmembrane transport GO:0055085 412 0.063
respiratory system development GO:0060541 190 0.063
nephron development GO:0072006 109 0.063
actin cytoskeleton organization GO:0030036 220 0.062
regulation of peptidase activity GO:0052547 96 0.062
Fly
positive regulation of protein kinase activity GO:0045860 144 0.062
cell adhesion GO:0007155 329 0.062
cell growth GO:0016049 130 0.062
regulation of system process GO:0044057 200 0.058
cellular homeostasis GO:0019725 240 0.058
cellular response to oxidative stress GO:0034599 76 0.058
tissue homeostasis GO:0001894 115 0.058
salivary gland development GO:0007431 37 0.058
regulation of cell cycle GO:0051726 281 0.054
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.053
positive regulation of programmed cell death GO:0043068 218 0.053
Mouse Fly
positive regulation of cell migration GO:0030335 109 0.052
leukocyte migration GO:0050900 124 0.051
t cell activation GO:0042110 289 0.051
small gtpase mediated signal transduction GO:0007264 97 0.051
apoptotic signaling pathway GO:0097190 306 0.051
Mouse
exocrine system development GO:0035272 45 0.050
cell chemotaxis GO:0060326 81 0.050
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.049
positive regulation of angiogenesis GO:0045766 46 0.048
odontogenesis GO:0042476 78 0.048
Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.047
regulation of neuron differentiation GO:0045664 281 0.047
cellular lipid metabolic process GO:0044255 323 0.047
response to inorganic substance GO:0010035 96 0.047
reactive oxygen species metabolic process GO:0072593 84 0.047
regulation of epithelial cell proliferation GO:0050678 141 0.046
Rat
salivary gland morphogenesis GO:0007435 33 0.046
regulation of cellular amine metabolic process GO:0033238 20 0.046
protein maturation GO:0051604 176 0.045
transmission of nerve impulse GO:0019226 76 0.045
negative regulation of cellular protein metabolic process GO:0032269 247 0.044
positive regulation of cell adhesion GO:0045785 80 0.044
fat cell differentiation GO:0045444 160 0.044
positive regulation of apoptotic process GO:0043065 217 0.044
Mouse Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.043
cellular ion homeostasis GO:0006873 165 0.043
cation transport GO:0006812 399 0.042
hemostasis GO:0007599 78 0.042
kidney development GO:0001822 213 0.042
urogenital system development GO:0001655 261 0.041
regulation of protein kinase activity GO:0045859 232 0.041
single organism cell adhesion GO:0098602 156 0.041
sensory perception GO:0007600 245 0.041
ion transmembrane transport GO:0034220 361 0.040
leukocyte differentiation GO:0002521 342 0.040
coagulation GO:0050817 78 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
action potential GO:0001508 78 0.040
response to reactive oxygen species GO:0000302 56 0.040
morphogenesis of embryonic epithelium GO:0016331 159 0.039
regulation of cell substrate adhesion GO:0010810 73 0.039
skeletal system morphogenesis GO:0048705 203 0.039
protein processing GO:0016485 163 0.039
peptidyl amino acid modification GO:0018193 336 0.039
muscle cell development GO:0055001 133 0.039
regulation of cell projection organization GO:0031344 206 0.039
connective tissue development GO:0061448 179 0.038
immune effector process GO:0002252 321 0.038
Rat
retinal blood vessel morphogenesis GO:0061304 3 0.038
positive regulation of cell substrate adhesion GO:0010811 47 0.038
neuropilin signaling pathway GO:0038189 2 0.038
tube formation GO:0035148 140 0.038
carbohydrate derivative biosynthetic process GO:1901137 183 0.038
retina development in camera type eye GO:0060041 119 0.038
negative regulation of immune system process GO:0002683 209 0.038
Rat
renal system development GO:0072001 225 0.036
g protein coupled receptor signaling pathway GO:0007186 243 0.036
metanephric glomerular basement membrane development GO:0072274 1 0.036
multicellular organismal signaling GO:0035637 91 0.035
glomerulus development GO:0032835 40 0.035
cell type specific apoptotic process GO:0097285 268 0.035
negative regulation of angiogenesis GO:0016525 25 0.035
negative regulation of cell motility GO:2000146 61 0.034
regulation of organelle organization GO:0033043 289 0.034
regulation of apoptotic signaling pathway GO:2001233 197 0.034
epithelial cell proliferation GO:0050673 174 0.034
Rat
regulation of cellular amino acid metabolic process GO:0006521 5 0.034
inorganic ion transmembrane transport GO:0098660 234 0.034
lipid biosynthetic process GO:0008610 179 0.034
regulation of kinase activity GO:0043549 249 0.033
response to organic cyclic compound GO:0014070 198 0.033
positive regulation of hydrolase activity GO:0051345 148 0.033
Fly
positive regulation of cell projection organization GO:0031346 95 0.032
epithelial cell development GO:0002064 159 0.032
response to amino acid GO:0043200 37 0.032
organophosphate biosynthetic process GO:0090407 122 0.032
endocytosis GO:0006897 168 0.032
regulation of map kinase activity GO:0043405 120 0.032
cation homeostasis GO:0055080 212 0.032
regulation of reactive oxygen species metabolic process GO:2000377 40 0.032
regulation of protein serine threonine kinase activity GO:0071900 157 0.032
blood coagulation GO:0007596 76 0.031
morphogenesis of a branching epithelium GO:0061138 193 0.031
mitotic cell cycle process GO:1903047 159 0.031
positive regulation of growth GO:0045927 104 0.031
negative regulation of phosphorylation GO:0042326 166 0.031
macromolecule catabolic process GO:0009057 281 0.030
myeloid leukocyte differentiation GO:0002573 119 0.030
regulation of cellular response to stress GO:0080135 159 0.030
negative regulation of proteolysis GO:0045861 74 0.030
regulation of response to oxidative stress GO:1902882 19 0.030
purine containing compound biosynthetic process GO:0072522 70 0.030
cytokine production GO:0001816 319 0.030
negative regulation of protein processing GO:0010955 79 0.030
ribose phosphate metabolic process GO:0019693 291 0.030
regulation of chemotaxis GO:0050920 53 0.030
regulation of cell activation GO:0050865 289 0.030
bone morphogenesis GO:0060349 78 0.029
synaptic transmission GO:0007268 329 0.029
purine nucleotide metabolic process GO:0006163 302 0.029
regulation of binding GO:0051098 111 0.029
multicellular organismal homeostasis GO:0048871 164 0.029
positive regulation of mapk cascade GO:0043410 170 0.029
negative regulation of phosphorus metabolic process GO:0010563 184 0.028
leukocyte proliferation GO:0070661 172 0.028
extrinsic apoptotic signaling pathway GO:0097191 126 0.028
branching morphogenesis of an epithelial tube GO:0048754 159 0.028
positive regulation of nervous system development GO:0051962 221 0.028
lymphocyte proliferation GO:0046651 164 0.028
regulation of neuron death GO:1901214 134 0.028
negative regulation of intracellular signal transduction GO:1902532 167 0.028
negative regulation of phosphate metabolic process GO:0045936 184 0.028
negative regulation of cell migration GO:0030336 59 0.028
negative regulation of vasculature development GO:1901343 26 0.028
regulation of cellular response to oxidative stress GO:1900407 19 0.027
platelet activation GO:0030168 40 0.027
myeloid cell differentiation GO:0030099 233 0.027
spermatogenesis GO:0007283 284 0.027
Fly
granulocyte migration GO:0097530 43 0.027
cation transmembrane transport GO:0098655 266 0.027
glycoprotein biosynthetic process GO:0009101 89 0.027
stem cell proliferation GO:0072089 117 0.027
cartilage development GO:0051216 140 0.027
biomineral tissue development GO:0031214 64 0.027
positive regulation of homeostatic process GO:0032846 64 0.027
nucleoside phosphate metabolic process GO:0006753 338 0.026
skin development GO:0043588 220 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
positive regulation of cell development GO:0010720 237 0.026
oxidation reduction process GO:0055114 342 0.026
bone mineralization GO:0030282 54 0.026
divalent inorganic cation transport GO:0072511 178 0.026
striated muscle cell development GO:0055002 125 0.026
divalent metal ion transport GO:0070838 172 0.026
hematopoietic progenitor cell differentiation GO:0002244 143 0.026
nucleotide metabolic process GO:0009117 332 0.026
erk1 and erk2 cascade GO:0070371 77 0.025
regulation of cellular response to growth factor stimulus GO:0090287 82 0.025
peptidyl tyrosine phosphorylation GO:0018108 143 0.025
metal ion homeostasis GO:0055065 189 0.025
neuron apoptotic process GO:0051402 142 0.025
superoxide metabolic process GO:0006801 27 0.025
tissue migration GO:0090130 68 0.025
t cell proliferation GO:0042098 120 0.025
endothelial cell migration GO:0043542 44 0.025
blood circulation GO:0008015 195 0.025
cellular metal ion homeostasis GO:0006875 151 0.025
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.025
ras protein signal transduction GO:0007265 77 0.025
protein kinase b signaling GO:0043491 74 0.025
cytoplasmic transport GO:0016482 234 0.024
regulation of cell shape GO:0008360 39 0.024
regulation of actin filament based process GO:0032970 99 0.024
striated muscle tissue development GO:0014706 293 0.024
leukocyte chemotaxis GO:0030595 69 0.024
appendage development GO:0048736 166 0.024
positive regulation of kinase activity GO:0033674 155 0.024
dna metabolic process GO:0006259 303 0.024
metanephros development GO:0001656 79 0.024
wound healing GO:0042060 157 0.024
regulation of protein binding GO:0043393 60 0.024
mitotic cell cycle GO:0000278 195 0.024
regulation of response to wounding GO:1903034 189 0.024
negative regulation of neuron differentiation GO:0045665 101 0.024
rho protein signal transduction GO:0007266 32 0.024
sequestering of calcium ion GO:0051208 18 0.023
chondrocyte differentiation GO:0002062 72 0.023
defense response to other organism GO:0098542 197 0.023
Rat
kidney epithelium development GO:0072073 121 0.023
metanephric epithelium development GO:0072207 21 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
regulation of secretion GO:0051046 274 0.023
kidney morphogenesis GO:0060993 83 0.023
sensory organ morphogenesis GO:0090596 242 0.023
renal tubule morphogenesis GO:0061333 72 0.023
regulation of homeostatic process GO:0032844 182 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
calcium ion transport GO:0006816 159 0.023
homeostasis of number of cells GO:0048872 210 0.023
regulation of hormone levels GO:0010817 211 0.023
ribonucleotide metabolic process GO:0009259 291 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.022
inflammatory response GO:0006954 244 0.022
regulation of protein kinase b signaling GO:0051896 56 0.022
circulatory system process GO:0003013 197 0.022
wnt signaling pathway GO:0016055 188 0.022
epithelial cell migration GO:0010631 63 0.022
reactive oxygen species biosynthetic process GO:1903409 8 0.022
negative regulation of cell activation GO:0050866 111 0.022
cell junction assembly GO:0034329 52 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
peptidyl tyrosine modification GO:0018212 145 0.022
purine containing compound metabolic process GO:0072521 311 0.022
membrane organization GO:0061024 245 0.022
myeloid leukocyte migration GO:0097529 57 0.022
negative regulation of molecular function GO:0044092 258 0.022
carbohydrate metabolic process GO:0005975 230 0.022
regulation of erk1 and erk2 cascade GO:0070372 71 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
regulation of cytokine production GO:0001817 266 0.021
visual learning GO:0008542 44 0.021
response to oxygen levels GO:0070482 62 0.021
negative regulation of protein maturation GO:1903318 79 0.021
glycoprotein metabolic process GO:0009100 116 0.021
divalent inorganic cation homeostasis GO:0072507 138 0.021
cellular component assembly involved in morphogenesis GO:0010927 139 0.021
glycosyl compound catabolic process GO:1901658 206 0.020
paracrine signaling GO:0038001 1 0.020
positive regulation of transferase activity GO:0051347 167 0.020
positive regulation of cytokine production GO:0001819 174 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
regulation of calcium ion transport GO:0051924 69 0.020
metanephric nephron epithelium development GO:0072243 19 0.020
lung alveolus development GO:0048286 45 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
multicellular organism growth GO:0035264 161 0.020
Mouse
regulation of blood coagulation GO:0030193 28 0.020
developmental maturation GO:0021700 193 0.020
regulation of secretion by cell GO:1903530 249 0.020
ensheathment of neurons GO:0007272 76 0.020
regulation of organ morphogenesis GO:2000027 144 0.019
compound eye development GO:0048749 1 0.019
regulation of ion transmembrane transport GO:0034765 119 0.019
nitrogen compound transport GO:0071705 271 0.019
regulation of neuron apoptotic process GO:0043523 122 0.019
forebrain development GO:0030900 302 0.019
Mouse
regulation of body fluid levels GO:0050878 162 0.019
neuron death GO:0070997 154 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
regulation of neuron projection development GO:0010975 169 0.019
negative regulation of apoptotic signaling pathway GO:2001234 104 0.019
positive regulation of secretion by cell GO:1903532 114 0.019
positive regulation of chemotaxis GO:0050921 38 0.019
small molecule biosynthetic process GO:0044283 132 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
regulation of epithelial cell migration GO:0010632 35 0.018
stem cell differentiation GO:0048863 268 0.018
cellular macromolecule catabolic process GO:0044265 206 0.018
negative regulation of blood vessel morphogenesis GO:2000181 25 0.018
epithelium migration GO:0090132 63 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.018
metanephric glomerular epithelium development GO:0072244 3 0.018
visual behavior GO:0007632 45 0.018
activation of mapk activity GO:0000187 59 0.018
regulation of transmembrane transport GO:0034762 128 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
digestive tract development GO:0048565 190 0.018
heterocycle catabolic process GO:0046700 280 0.018
positive regulation of muscle cell differentiation GO:0051149 39 0.018
glycosyl compound metabolic process GO:1901657 246 0.018
cellular chemical homeostasis GO:0055082 215 0.018
apical constriction GO:0003383 4 0.018
cellular calcium ion homeostasis GO:0006874 119 0.018
regulation of cell cycle process GO:0010564 160 0.018
organophosphate catabolic process GO:0046434 232 0.017
digestive tract morphogenesis GO:0048546 147 0.017
cardiac muscle fiber development GO:0048739 4 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
heart process GO:0003015 94 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
regulation of ossification GO:0030278 112 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
positive regulation of map kinase activity GO:0043406 84 0.017
elastic fiber assembly GO:0048251 4 0.017
heart contraction GO:0060047 93 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
regulation of cytoskeleton organization GO:0051493 122 0.017
response to acid chemical GO:0001101 111 0.017
cardiocyte differentiation GO:0035051 87 0.017
myotube differentiation GO:0014902 105 0.017
cardiac muscle cell differentiation GO:0055007 69 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
cytosolic calcium ion transport GO:0060401 48 0.017
cellular response to superoxide GO:0071451 14 0.017
cellular divalent inorganic cation homeostasis GO:0072503 127 0.017
limb development GO:0060173 166 0.016
negative regulation of neuron apoptotic process GO:0043524 92 0.016
bmp signaling pathway GO:0030509 93 0.016
microtubule based process GO:0007017 236 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
visual perception GO:0007601 52 0.016
regulation of vesicle mediated transport GO:0060627 139 0.016
response to peptide GO:1901652 136 0.016
regulation of muscle tissue development GO:1901861 97 0.016
myelination GO:0042552 74 0.016
nucleoside phosphate biosynthetic process GO:1901293 79 0.016
neuron projection extension GO:1990138 64 0.016
regulation of branching involved in salivary gland morphogenesis by extracellular matrix epithelial cell signaling GO:0060668 1 0.016
basement membrane organization GO:0071711 8 0.016
immune response regulating signaling pathway GO:0002764 125 0.016
positive regulation of protein autophosphorylation GO:0031954 4 0.016
canonical wnt signaling pathway GO:0060070 130 0.016
sulfur compound metabolic process GO:0006790 100 0.016
regulation of t cell activation GO:0050863 170 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
regulation of protein localization GO:0032880 231 0.015
heart morphogenesis GO:0003007 178 0.015
nephron tubule development GO:0072080 84 0.015
regulation of membrane potential GO:0042391 192 0.015
cellular response to oxygen radical GO:0071450 14 0.015
placenta development GO:0001890 140 0.015
ureteric bud morphogenesis GO:0060675 62 0.015
regulation of protein processing GO:0070613 96 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
bone resorption GO:0045453 38 0.015
regulation of removal of superoxide radicals GO:2000121 4 0.015
negative regulation of protein phosphorylation GO:0001933 126 0.015
positive regulation of smooth muscle cell migration GO:0014911 4 0.015
positive regulation of proteolysis GO:0045862 85 0.015
Fly
macromolecule glycosylation GO:0043413 55 0.015
protein hydroxylation GO:0018126 4 0.015
nucleoside triphosphate catabolic process GO:0009143 205 0.015
phosphatidylinositol metabolic process GO:0046488 45 0.015
multi multicellular organism process GO:0044706 109 0.015
regulation of store operated calcium channel activity GO:1901339 1 0.015
negative regulation of ossification GO:0030279 49 0.015
organelle assembly GO:0070925 177 0.015
response to peptide hormone GO:0043434 127 0.015
regulation of endocytosis GO:0030100 69 0.015
negative regulation of cell development GO:0010721 169 0.015
regulation of bmp signaling pathway GO:0030510 60 0.015
g1 s transition of mitotic cell cycle GO:0000082 57 0.015
gliogenesis GO:0042063 141 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
neuronal action potential GO:0019228 54 0.015
brown fat cell differentiation GO:0050873 36 0.015
single organismal cell cell adhesion GO:0016337 131 0.015
locomotory behavior GO:0007626 195 0.015
Mouse
cell cell junction organization GO:0045216 72 0.014
regulation of anatomical structure size GO:0090066 178 0.014
regulation of cell growth GO:0001558 91 0.014
mesonephric tubule morphogenesis GO:0072171 63 0.014
cellular protein complex assembly GO:0043623 116 0.014
fertilization GO:0009566 127 0.014
stem cell development GO:0048864 219 0.014
sensory perception of light stimulus GO:0050953 54 0.014
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.014
nephron epithelium development GO:0072009 92 0.014
ceramide metabolic process GO:0006672 31 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.014
actin mediated cell contraction GO:0070252 15 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
regulation of establishment of protein localization GO:0070201 181 0.014
cyclic nucleotide metabolic process GO:0009187 59 0.014
camp metabolic process GO:0046058 40 0.014
multicellular organismal macromolecule metabolic process GO:0044259 19 0.014
regulation of metal ion transport GO:0010959 106 0.014
nephron tubule morphogenesis GO:0072078 68 0.014
positive regulation of secretion GO:0051047 130 0.014
axial mesodermal cell fate commitment GO:0048322 1 0.014
ureteric bud development GO:0001657 94 0.014
organic hydroxy compound biosynthetic process GO:1901617 77 0.014
inner ear morphogenesis GO:0042472 101 0.014
positive regulation of cell cycle GO:0045787 92 0.014
regulation of production of molecular mediator of immune response GO:0002700 65 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
striated muscle contraction GO:0006941 45 0.014
positive regulation of organelle organization GO:0010638 128 0.014
formation of primary germ layer GO:0001704 77 0.014
integrin mediated signaling pathway GO:0007229 27 0.014
positive regulation of behavior GO:0048520 40 0.013
peptide metabolic process GO:0006518 46 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
mesenchyme development GO:0060485 152 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
sphingolipid metabolic process GO:0006665 45 0.013
regulation of biomineral tissue development GO:0070167 33 0.013
response to steroid hormone GO:0048545 56 0.013
ribose phosphate biosynthetic process GO:0046390 59 0.013
response to superoxide GO:0000303 16 0.013
glycerophospholipid biosynthetic process GO:0046474 32 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
Fly
striated muscle myosin thick filament assembly GO:0071688 1 0.013
regulation of intracellular transport GO:0032386 159 0.013
ribonucleotide catabolic process GO:0009261 208 0.013
nucleoside catabolic process GO:0009164 206 0.013
nucleotide biosynthetic process GO:0009165 78 0.013
production of molecular mediator of immune response GO:0002440 103 0.013
leukocyte mediated immunity GO:0002443 174 0.013
adult behavior GO:0030534 135 0.013
Mouse
cellular amide metabolic process GO:0043603 58 0.013
odontogenesis of dentin containing tooth GO:0042475 66 0.013
Rat
mesonephric epithelium development GO:0072163 94 0.013
mesonephros development GO:0001823 97 0.013
actin filament based movement GO:0030048 23 0.013
axon ensheathment GO:0008366 76 0.013
immune response activating signal transduction GO:0002757 116 0.013
substrate dependent cell migration GO:0006929 18 0.013
removal of superoxide radicals GO:0019430 12 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.013
regulation of protein maturation GO:1903317 96 0.013
mineralocorticoid biosynthetic process GO:0006705 1 0.013
energy derivation by oxidation of organic compounds GO:0015980 77 0.013
positive regulation of peptidase activity GO:0010952 49 0.013
Fly
syncytium formation by plasma membrane fusion GO:0000768 42 0.013
lipid localization GO:0010876 126 0.013
proteoglycan metabolic process GO:0006029 38 0.013
cerebral cortex development GO:0021987 86 0.012
regulation of actin cytoskeleton organization GO:0032956 84 0.012
regulation of defense response GO:0031347 233 0.012
Rat
cytosolic calcium ion homeostasis GO:0051480 70 0.012
tendon cell differentiation GO:0035990 4 0.012

Htra1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.095
Human
nervous system disease DOID:863 0 0.095
Human
sensory system disease DOID:0050155 0 0.057
Human
eye and adnexa disease DOID:1492 0 0.056
Human
eye disease DOID:5614 0 0.056
Human
musculoskeletal system disease DOID:17 0 0.046
central nervous system disease DOID:331 0 0.042
myopathy DOID:423 0 0.030
muscular disease DOID:0080000 0 0.030
muscle tissue disease DOID:66 0 0.030
immune system disease DOID:2914 0 0.029
retinal disease DOID:5679 0 0.026
Human
retinal degeneration DOID:8466 0 0.025
Human
bone development disease DOID:0080006 0 0.023
bone disease DOID:0080001 0 0.023
connective tissue disease DOID:65 0 0.023
neuropathy DOID:870 0 0.020
hematopoietic system disease DOID:74 0 0.015
muscular dystrophy DOID:9884 0 0.013
neurodegenerative disease DOID:1289 0 0.013