|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.937
|
Worm Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.877
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.838
|
Worm Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.705
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.692
|
Fly |
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.627
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.568
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.567
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.532
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.511
|
Rat |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.508
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.499
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.489
|
|
|
|
macroautophagy
|
GO:0016236 |
21 |
0.480
|
Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.461
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.446
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.437
|
Mouse |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.434
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.434
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.433
|
Mouse Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.432
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.424
|
Human |
|
|
photoreceptor cell morphogenesis
|
GO:0008594 |
3 |
0.398
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.391
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.386
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.379
|
Rat |
|
|
learning or memory
|
GO:0007611 |
148 |
0.374
|
Mouse |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.365
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.358
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.356
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.348
|
Mouse Rat Fly |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.346
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.334
|
Mouse |
|
|
dna replication
|
GO:0006260 |
52 |
0.329
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.328
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.327
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.326
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.324
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
47 |
0.322
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.321
|
Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.320
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.318
|
Fly |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.318
|
Worm |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.316
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.311
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.311
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.308
|
Mouse Rat Fly |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.301
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.301
|
Fly |
|
|
cell fate specification
|
GO:0001708 |
72 |
0.300
|
Worm |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.299
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.298
|
Mouse |
|
|
carbon catabolite activation of transcription
|
GO:0045991 |
4 |
0.295
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.290
|
Mouse Fly |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.288
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.286
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.282
|
Mouse Fly |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.270
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.270
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.265
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.258
|
|
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
13 |
0.258
|
Fly |
|
|
positive regulation of rac protein signal transduction
|
GO:0035022 |
1 |
0.251
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.250
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.250
|
Fly |
|
|
negative regulation of macroautophagy
|
GO:0016242 |
5 |
0.238
|
Fly |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.236
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.234
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.232
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.232
|
Fly |
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.230
|
Fly |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.230
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.229
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.229
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.227
|
Rat |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.227
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.223
|
|
|
|
positive regulation of transcription by galactose
|
GO:0000411 |
1 |
0.222
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.220
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.218
|
Rat |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.216
|
|
|
|
positive regulation of rap gtpase activity
|
GO:0032854 |
3 |
0.215
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.214
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.212
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.210
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.209
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.209
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.208
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.207
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.203
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.203
|
|
|
|
dna repair
|
GO:0006281 |
107 |
0.202
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.200
|
Mouse Fly |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.200
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
73 |
0.200
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.199
|
Rat |
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.198
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.198
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.197
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.196
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.195
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.194
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.193
|
Mouse |
|
|
gonad development
|
GO:0008406 |
141 |
0.193
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.190
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.190
|
Human Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.188
|
Rat |
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.183
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.183
|
Human Rat |
|
|
lung development
|
GO:0030324 |
164 |
0.183
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
58 |
0.181
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.177
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.175
|
Rat |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.175
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.173
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.171
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.171
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.170
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.169
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.168
|
Mouse Rat Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.167
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.167
|
|
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.167
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.165
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.165
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.163
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.163
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.163
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.160
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
13 |
0.155
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.155
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.155
|
|
|
|
localization within membrane
|
GO:0051668 |
4 |
0.153
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.153
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.151
|
Fly |
|
|
oocyte development
|
GO:0048599 |
33 |
0.150
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.150
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.150
|
Fly |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.149
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.149
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.148
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.147
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.144
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.143
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.141
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.141
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.140
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.138
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.137
|
Mouse |
|
|
regulation of transcription by galactose
|
GO:0000409 |
1 |
0.137
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.136
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.133
|
Rat |
|
|
wound healing
|
GO:0042060 |
157 |
0.131
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.131
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.130
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.128
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.128
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.128
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.126
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.125
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.123
|
Mouse |
|
|
tor signaling
|
GO:0031929 |
21 |
0.122
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.122
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.122
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.121
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.121
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.121
|
|
|
|
visual behavior
|
GO:0007632 |
45 |
0.120
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.120
|
Rat |
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.119
|
Mouse |
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.119
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.118
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.118
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
77 |
0.117
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.116
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.115
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.115
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.115
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.114
|
Mouse |
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.114
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.113
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.113
|
Human |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.112
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.112
|
Mouse |
|
|
negative regulation of autophagy
|
GO:0010507 |
9 |
0.111
|
Fly |
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.111
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.111
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.109
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.108
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.108
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.106
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.106
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.106
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.105
|
|
|
|
cell cycle arrest
|
GO:0007050 |
37 |
0.105
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.105
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
45 |
0.104
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.103
|
Mouse |
|
|
cell maturation
|
GO:0048469 |
127 |
0.103
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.103
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.103
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.103
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.102
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.100
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.100
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
28 |
0.100
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.099
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.099
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.098
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.098
|
Fly |
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.098
|
|
|
|
carbon catabolite regulation of transcription
|
GO:0045990 |
4 |
0.097
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.096
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.096
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.096
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.096
|
|
|
|
regulation of macroautophagy
|
GO:0016241 |
12 |
0.096
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.095
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.095
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.094
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.094
|
Fly |
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.094
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.093
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.092
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.092
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.091
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.091
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.090
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.089
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
3 |
0.089
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.089
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
70 |
0.088
|
|
|
|
cell aging
|
GO:0007569 |
35 |
0.088
|
|
|
|
negative regulation of fibroblast migration
|
GO:0010764 |
2 |
0.088
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.088
|
Human Mouse |
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.087
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
95 |
0.087
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
48 |
0.087
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.087
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.087
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.086
|
|
|
|
cellular senescence
|
GO:0090398 |
11 |
0.086
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.086
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
44 |
0.085
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.085
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.085
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.084
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.083
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.083
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.083
|
Mouse |
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.083
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.082
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.081
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.080
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.080
|
|
|
|
multi organism behavior
|
GO:0051705 |
62 |
0.080
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.080
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.079
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.079
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.079
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.079
|
|
|
|
regulation of rac protein signal transduction
|
GO:0035020 |
19 |
0.079
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.078
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.077
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.077
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.077
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.077
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.077
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.076
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.075
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.075
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.075
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.075
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.075
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.074
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.073
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.073
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.072
|
Fly |
|
|
regulation of myelination
|
GO:0031641 |
20 |
0.072
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.072
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.072
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.071
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.071
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.071
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.070
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.070
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.069
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.069
|
|
|
|
multicellular organismal reproductive behavior
|
GO:0033057 |
23 |
0.069
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.069
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.069
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.069
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.069
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.069
|
Mouse |
|
|
response to starvation
|
GO:0042594 |
65 |
0.069
|
Fly |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.069
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.068
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
69 |
0.068
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.068
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.068
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.068
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.067
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.067
|
Mouse |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.067
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.067
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.067
|
Fly |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.067
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.066
|
|
|
|
memory
|
GO:0007613 |
58 |
0.066
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.065
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.065
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.065
|
|
|
|
learning
|
GO:0007612 |
98 |
0.065
|
Mouse |
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.064
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.064
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.064
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.064
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.062
|
Mouse |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.062
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.061
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.061
|
Rat |
|
|
myelination
|
GO:0042552 |
74 |
0.061
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.061
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.061
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.060
|
|
|
|
lung morphogenesis
|
GO:0060425 |
50 |
0.060
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.060
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.060
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.059
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.059
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.059
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.059
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.058
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.058
|
Mouse |
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
21 |
0.057
|
|
|
|
regulation of synaptic transmission gabaergic
|
GO:0032228 |
17 |
0.057
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.057
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.056
|
Fly |
|
|
dna damage checkpoint
|
GO:0000077 |
26 |
0.056
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.056
|
|
|
|
stem cell fate commitment
|
GO:0048865 |
5 |
0.055
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.055
|
Fly |
|
|
histone modification
|
GO:0016570 |
159 |
0.055
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.055
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.055
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.055
|
Fly |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.054
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.054
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.054
|
|
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.054
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.054
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.054
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.054
|
Fly |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.053
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.053
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
31 |
0.053
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.053
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.053
|
Fly |
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
59 |
0.053
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.053
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.053
|
Fly |
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.052
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.052
|
|
|
|
dna alkylation
|
GO:0006305 |
43 |
0.052
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.052
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.052
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.052
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.052
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.052
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.052
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.052
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.051
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.051
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.051
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.051
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.051
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.051
|
|
|
|
positive regulation of nitric oxide synthase activity
|
GO:0051000 |
2 |
0.051
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.051
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.051
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.051
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.051
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.051
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.050
|
Mouse |
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.050
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.050
|
Mouse Fly |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.050
|
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.050
|
|
|
|
positive regulation of dna biosynthetic process
|
GO:2000573 |
4 |
0.050
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.050
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.050
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.050
|
|
|
|
cell fate determination
|
GO:0001709 |
32 |
0.050
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.049
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.049
|
Mouse |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.049
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.049
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.048
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.048
|
|
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.048
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.048
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
32 |
0.047
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.047
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.046
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.046
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.046
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.045
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.045
|
|
|
|
negative regulation of organ growth
|
GO:0046621 |
17 |
0.045
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.045
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.044
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.044
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.044
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.044
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.044
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.044
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.043
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.043
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.043
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.042
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.042
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
21 |
0.042
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.042
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.042
|
|
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
57 |
0.042
|
Mouse |
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.042
|
|
|
|
visual learning
|
GO:0008542 |
44 |
0.042
|
Mouse |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.042
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.042
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.041
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.041
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.041
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.041
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.041
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.040
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.040
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.040
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.040
|
Mouse |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.040
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.040
|
|
|
|
regulation of purine nucleotide biosynthetic process
|
GO:1900371 |
34 |
0.039
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.039
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.039
|
|
|
|
vesicle localization
|
GO:0051648 |
86 |
0.039
|
Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.039
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.039
|
|
|
|
social behavior
|
GO:0035176 |
21 |
0.039
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.038
|
Mouse |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.038
|
|
|
|
regulation of long term neuronal synaptic plasticity
|
GO:0048169 |
19 |
0.038
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.038
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.038
|
Fly |
|
|
synaptic transmission gabaergic
|
GO:0051932 |
19 |
0.038
|
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.038
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.037
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.037
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.037
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.037
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.037
|
Mouse |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.037
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.037
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.037
|
|
|
|
dna modification
|
GO:0006304 |
50 |
0.037
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
20 |
0.036
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.036
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.036
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.036
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.036
|
|
|
|
regulation of epidermal cell differentiation
|
GO:0045604 |
21 |
0.036
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.035
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.035
|
Mouse |
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.035
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.035
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.035
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.035
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
87 |
0.035
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.035
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.034
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.034
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.034
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.034
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
43 |
0.034
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.034
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.034
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.034
|
Fly |
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.034
|
|
|
|
regulation of exit from mitosis
|
GO:0007096 |
1 |
0.034
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.033
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.033
|
|
