Mus musculus

38 known processes

Nhlrc1

NHL repeat containing 1

(Aliases: EPM2B,AI505271,B230309E09Rik)

Nhlrc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 103 0.087
regulation of cellular amine metabolic process GO:0033238 20 0.049
cellular amine metabolic process GO:0044106 44 0.048
g protein coupled receptor signaling pathway GO:0007186 243 0.047
protein modification by small protein conjugation or removal GO:0070647 207 0.045
cation transport GO:0006812 399 0.044
macromolecule catabolic process GO:0009057 281 0.042
Human Mouse
protein modification by small protein conjugation GO:0032446 187 0.039
protein catabolic process GO:0030163 221 0.037
Human Mouse
transmembrane transport GO:0055085 412 0.036
protein ubiquitination GO:0016567 171 0.035
inorganic ion transmembrane transport GO:0098660 234 0.035
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
male gamete generation GO:0048232 285 0.033
amine metabolic process GO:0009308 45 0.032
cellular macromolecule catabolic process GO:0044265 206 0.031
Human
cation transmembrane transport GO:0098655 266 0.031
muscle tissue development GO:0060537 308 0.030
peptidyl amino acid modification GO:0018193 336 0.030
regulation of organelle organization GO:0033043 289 0.030
cellular ketone metabolic process GO:0042180 84 0.029
apoptotic signaling pathway GO:0097190 306 0.029
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
ion transmembrane transport GO:0034220 361 0.028
regulation of membrane potential GO:0042391 192 0.027
cell type specific apoptotic process GO:0097285 268 0.026
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.025
skeletal system development GO:0001501 356 0.025
microtubule based process GO:0007017 236 0.025
purine containing compound metabolic process GO:0072521 311 0.025
negative regulation of cell proliferation GO:0008285 296 0.024
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.024
spermatogenesis GO:0007283 284 0.023
oxidation reduction process GO:0055114 342 0.023
cellular homeostasis GO:0019725 240 0.023
cellular protein catabolic process GO:0044257 155 0.023
Human
dna metabolic process GO:0006259 303 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
Mouse
cation homeostasis GO:0055080 212 0.022
cell adhesion GO:0007155 329 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.022
sensory perception GO:0007600 245 0.022
germ cell development GO:0007281 185 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.021
Human
purine nucleotide metabolic process GO:0006163 302 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
Mouse
negative regulation of cellular component organization GO:0051129 194 0.021
nucleotide metabolic process GO:0009117 332 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
neuronal action potential GO:0019228 54 0.021
multicellular organismal homeostasis GO:0048871 164 0.020
nitrogen compound transport GO:0071705 271 0.020
mitochondrion organization GO:0007005 134 0.020
renal system development GO:0072001 225 0.020
ribonucleotide metabolic process GO:0009259 291 0.020
locomotory behavior GO:0007626 195 0.019
response to organonitrogen compound GO:0010243 246 0.019
maintenance of location GO:0051235 89 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
Human
regulation of secretion GO:0051046 274 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
nuclear division GO:0000280 158 0.019
organelle localization GO:0051640 179 0.019
cytoplasmic transport GO:0016482 234 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
Mouse
fertilization GO:0009566 127 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
synaptic transmission GO:0007268 329 0.018
mitotic cell cycle process GO:1903047 159 0.018
Mouse
modification dependent protein catabolic process GO:0019941 133 0.018
Human
organonitrogen compound biosynthetic process GO:1901566 192 0.018
organelle fission GO:0048285 170 0.018
muscle system process GO:0003012 141 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
protein localization to organelle GO:0033365 185 0.018
transmission of nerve impulse GO:0019226 76 0.018
negative regulation of nervous system development GO:0051961 156 0.018
positive regulation of cell death GO:0010942 224 0.018
positive regulation of apoptotic process GO:0043065 217 0.018
action potential GO:0001508 78 0.018
myeloid cell differentiation GO:0030099 233 0.018
regulation of protein localization GO:0032880 231 0.017
positive regulation of protein modification process GO:0031401 299 0.017
regulation of cell cycle GO:0051726 281 0.017
cellular lipid metabolic process GO:0044255 323 0.017
mitotic cell cycle GO:0000278 195 0.017
Mouse
regulation of feeding behavior GO:0060259 3 0.017
adult behavior GO:0030534 135 0.017
positive regulation of cell development GO:0010720 237 0.017
Mouse
cell fate commitment GO:0045165 210 0.017
skeletal muscle organ development GO:0060538 163 0.017
lateral inhibition GO:0046331 1 0.017
cellular chemical homeostasis GO:0055082 215 0.017
regulation of hormone levels GO:0010817 211 0.017
reactive oxygen species metabolic process GO:0072593 84 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
Mouse
leukocyte differentiation GO:0002521 342 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
anatomical structure homeostasis GO:0060249 145 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
connective tissue development GO:0061448 179 0.016
negative regulation of intracellular signal transduction GO:1902532 167 0.016
membrane organization GO:0061024 245 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of cellular catabolic process GO:0031329 242 0.016
homeostasis of number of cells GO:0048872 210 0.016
aromatic compound catabolic process GO:0019439 286 0.016
anion transport GO:0006820 177 0.016
multicellular organismal signaling GO:0035637 91 0.016
regulation of ion transport GO:0043269 215 0.016
metal ion homeostasis GO:0055065 189 0.016
organic hydroxy compound metabolic process GO:1901615 203 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
blood vessel morphogenesis GO:0048514 285 0.016
cellular protein complex assembly GO:0043623 116 0.016
muscle cell differentiation GO:0042692 261 0.016
forebrain development GO:0030900 302 0.015
amide transport GO:0042886 138 0.015
regulation of homeostatic process GO:0032844 182 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
dephosphorylation GO:0016311 129 0.015
regulation of kinase activity GO:0043549 249 0.015
regulation of neuron differentiation GO:0045664 281 0.015
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.015
rho protein signal transduction GO:0007266 32 0.015
heterocycle catabolic process GO:0046700 280 0.015
stem cell differentiation GO:0048863 268 0.015
striated muscle tissue development GO:0014706 293 0.015
meiotic cell cycle GO:0051321 122 0.014
immune effector process GO:0002252 321 0.014
respiratory tube development GO:0030323 167 0.014
divalent metal ion transport GO:0070838 172 0.014
regulation of cell cycle process GO:0010564 160 0.014
spermatid development GO:0007286 108 0.014
regulation of intracellular transport GO:0032386 159 0.014
fat cell differentiation GO:0045444 160 0.014
Mouse
positive regulation of nervous system development GO:0051962 221 0.014
Mouse
peptide transport GO:0015833 133 0.014
developmental maturation GO:0021700 193 0.014
sequestering of calcium ion GO:0051208 18 0.014
response to acid chemical GO:0001101 111 0.014
respiratory system development GO:0060541 190 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
establishment of organelle localization GO:0051656 122 0.014
lipid biosynthetic process GO:0008610 179 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
cellular metal ion homeostasis GO:0006875 151 0.014
cellular nitrogen compound catabolic process GO:0044270 280 0.014
regulation of blood pressure GO:0008217 93 0.014
regulation of proteolysis GO:0030162 164 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
gland development GO:0048732 330 0.013
negative regulation of immune system process GO:0002683 209 0.013
cellular response to dna damage stimulus GO:0006974 207 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
organelle assembly GO:0070925 177 0.013
cellular response to lipid GO:0071396 145 0.013
regulation of cell activation GO:0050865 289 0.013
lymphocyte differentiation GO:0030098 242 0.013
cartilage development GO:0051216 140 0.013
single fertilization GO:0007338 82 0.013
organic cyclic compound catabolic process GO:1901361 295 0.013
oocyte anterior posterior axis specification GO:0007314 2 0.013
adult locomotory behavior GO:0008344 91 0.013
regulation of reactive oxygen species metabolic process GO:2000377 40 0.013
peptide secretion GO:0002790 114 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
tissue homeostasis GO:0001894 115 0.013
regulation of secretion by cell GO:1903530 249 0.013
regulation of leukocyte differentiation GO:1902105 159 0.013
myeloid leukocyte differentiation GO:0002573 119 0.013
neural precursor cell proliferation GO:0061351 121 0.013
Mouse
oocyte construction GO:0007308 2 0.013
intracellular protein transport GO:0006886 204 0.013
spermatid differentiation GO:0048515 115 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.013
regulation of neuron death GO:1901214 134 0.013
Mouse
lipid localization GO:0010876 126 0.013
sequestering of metal ion GO:0051238 19 0.013
mapk cascade GO:0000165 281 0.013
potassium ion transmembrane transport GO:0071805 43 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
axonogenesis GO:0007409 274 0.012
negative regulation of cell development GO:0010721 169 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
Human
response to lipopolysaccharide GO:0032496 128 0.012
multicellular organism growth GO:0035264 161 0.012
divalent inorganic cation homeostasis GO:0072507 138 0.012
myelination GO:0042552 74 0.012
circulatory system process GO:0003013 197 0.012
ossification GO:0001503 216 0.012
telencephalon development GO:0021537 186 0.012
organic acid transport GO:0015849 101 0.012
purine ribonucleoside metabolic process GO:0046128 241 0.012
single organism cell adhesion GO:0098602 156 0.012
cellularization GO:0007349 1 0.012
regulation of cell adhesion GO:0030155 154 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
t cell activation GO:0042110 289 0.012
compound eye development GO:0048749 1 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
Mouse
regulation of t cell activation GO:0050863 170 0.012
regulation of nucleotide metabolic process GO:0006140 169 0.012
organic anion transport GO:0015711 137 0.012
carbohydrate metabolic process GO:0005975 230 0.012
glycoprotein metabolic process GO:0009100 116 0.012
regionalization GO:0003002 337 0.012
methylation GO:0032259 134 0.012
negative regulation of organelle organization GO:0010639 90 0.012
intrinsic apoptotic signaling pathway GO:0097193 132 0.012
hormone secretion GO:0046879 128 0.012
cytokine production GO:0001816 319 0.012
negative regulation of protein modification process GO:0031400 163 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
organophosphate catabolic process GO:0046434 232 0.012
regulation of system process GO:0044057 200 0.012
chromatin organization GO:0006325 206 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
stem cell development GO:0048864 219 0.012
learning or memory GO:0007611 148 0.012
lung development GO:0030324 164 0.012
small molecule biosynthetic process GO:0044283 132 0.012
alcohol metabolic process GO:0006066 116 0.012
negative regulation of neuron differentiation GO:0045665 101 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
cognition GO:0050890 149 0.012
nuclear transport GO:0051169 139 0.012
glycosyl compound metabolic process GO:1901657 246 0.012
regulation of cell migration GO:0030334 219 0.012
response to organic cyclic compound GO:0014070 198 0.012
mrna metabolic process GO:0016071 84 0.012
response to growth factor GO:0070848 198 0.012
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.011
kidney development GO:0001822 213 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
endocytosis GO:0006897 168 0.011
morphogenesis of a branching structure GO:0001763 203 0.011
epithelial tube formation GO:0072175 130 0.011
Mouse
epithelial cell development GO:0002064 159 0.011
epithelial cell proliferation GO:0050673 174 0.011
negative regulation of cell cycle GO:0045786 123 0.011
striated muscle myosin thick filament assembly GO:0071688 1 0.011
skin development GO:0043588 220 0.011
bone development GO:0060348 120 0.011
response to inorganic substance GO:0010035 96 0.011
regulation of mapk cascade GO:0043408 248 0.011
cellular response to hormone stimulus GO:0032870 150 0.011
regulation of cell projection organization GO:0031344 206 0.011
regulation of anatomical structure size GO:0090066 178 0.011
regulation of protein kinase activity GO:0045859 232 0.011
cell maturation GO:0048469 127 0.011
response to radiation GO:0009314 165 0.011
Mouse
placenta development GO:0001890 140 0.011
maternal determination of anterior posterior axis embryo GO:0008358 2 0.011
oocyte axis specification GO:0007309 2 0.011
cellular response to cytokine stimulus GO:0071345 189 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
inflammatory response GO:0006954 244 0.011
peptide hormone secretion GO:0030072 109 0.011
protein maturation GO:0051604 176 0.011
b cell activation GO:0042113 161 0.011
rhythmic process GO:0048511 174 0.011
regulation of cytokine production GO:0001817 266 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
neural tube development GO:0021915 160 0.011
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.011
extracellular matrix organization GO:0030198 147 0.011
sensory organ morphogenesis GO:0090596 242 0.011
pole plasm assembly GO:0007315 2 0.011
carboxylic acid biosynthetic process GO:0046394 86 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
lipid transport GO:0006869 98 0.011
response to light stimulus GO:0009416 135 0.011
Mouse
protein localization to nucleus GO:0034504 121 0.011
ras protein signal transduction GO:0007265 77 0.011
transition metal ion homeostasis GO:0055076 54 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.010
muscle contraction GO:0006936 101 0.010
ribonucleoside monophosphate metabolic process GO:0009161 80 0.010
cell division GO:0051301 120 0.010
divalent inorganic cation transport GO:0072511 178 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
dna repair GO:0006281 107 0.010
positive regulation of ion transport GO:0043270 65 0.010
myosin filament assembly GO:0031034 2 0.010
digestive system development GO:0055123 200 0.010
proteasomal protein catabolic process GO:0010498 98 0.010
Human
heart morphogenesis GO:0003007 178 0.010
positive regulation of organelle organization GO:0010638 128 0.010
neuron death GO:0070997 154 0.010
Mouse
gliogenesis GO:0042063 141 0.010
regulation of circadian sleep wake cycle GO:0042749 3 0.010
potassium ion transport GO:0006813 52 0.010
cofactor metabolic process GO:0051186 80 0.010

Nhlrc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
Human
nervous system disease DOID:863 0 0.057
Human
central nervous system disease DOID:331 0 0.017
Human
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
sensory system disease DOID:0050155 0 0.011
brain disease DOID:936 0 0.011
Human
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010