Mus musculus

0 known processes

Eme1

essential meiotic endonuclease 1 homolog 1 (S. pombe)

(Aliases: 6820428D13,MGC106543)

Eme1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 303 0.601
dna repair GO:0006281 107 0.316
meiotic nuclear division GO:0007126 115 0.239
nuclear division GO:0000280 158 0.130
organic cyclic compound catabolic process GO:1901361 295 0.127
cellular response to dna damage stimulus GO:0006974 207 0.113
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.108
organelle fission GO:0048285 170 0.090
organonitrogen compound catabolic process GO:1901565 264 0.088
cellular nitrogen compound catabolic process GO:0044270 280 0.087
metaphase plate congression GO:0051310 2 0.086
meiotic cell cycle GO:0051321 122 0.085
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.081
mitotic sister chromatid cohesion GO:0007064 1 0.079
cellular amino acid metabolic process GO:0006520 103 0.075
heterocycle catabolic process GO:0046700 280 0.071
regulation of cell cycle GO:0051726 281 0.068
macromolecule catabolic process GO:0009057 281 0.068
male meiosis GO:0007140 37 0.068
nucleoside metabolic process GO:0009116 246 0.066
regulation of organelle organization GO:0033043 289 0.060
spindle assembly involved in mitosis GO:0090307 4 0.056
mitotic cell cycle process GO:1903047 159 0.055
microtubule based process GO:0007017 236 0.054
cell division GO:0051301 120 0.052
nucleoside catabolic process GO:0009164 206 0.051
gland development GO:0048732 330 0.050
meiotic cell cycle process GO:1903046 77 0.050
purine nucleotide catabolic process GO:0006195 211 0.049
atp catabolic process GO:0006200 55 0.049
protein catabolic process GO:0030163 221 0.049
regulation of cell cycle process GO:0010564 160 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
ribonucleoside metabolic process GO:0009119 245 0.045
purine nucleoside catabolic process GO:0006152 205 0.044
histone modification GO:0016570 159 0.042
purine ribonucleoside metabolic process GO:0046128 241 0.041
nucleoside triphosphate catabolic process GO:0009143 205 0.040
regulation of mitotic cell cycle phase transition GO:1901990 73 0.039
organelle assembly GO:0070925 177 0.039
negative regulation of cell cycle phase transition GO:1901988 48 0.037
centrosome separation GO:0051299 4 0.037
negative regulation of cellular component organization GO:0051129 194 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.037
purine nucleoside metabolic process GO:0042278 241 0.036
mitotic chromosome condensation GO:0007076 1 0.035
chromosome segregation GO:0007059 48 0.035
centrosome organization GO:0051297 26 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.033
spermatogenesis GO:0007283 284 0.033
modification dependent macromolecule catabolic process GO:0043632 133 0.033
response to cell cycle checkpoint signaling GO:0072396 1 0.033
Human
mitotic cell cycle GO:0000278 195 0.032
positive regulation of chromosome segregation GO:0051984 4 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
regulation of cellular amine metabolic process GO:0033238 20 0.031
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.031
glycosyl compound metabolic process GO:1901657 246 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
cleavage furrow formation GO:0036089 2 0.031
protein modification by small protein conjugation GO:0032446 187 0.029
chromatin silencing GO:0006342 15 0.029
regulation of cellular amino acid metabolic process GO:0006521 5 0.029
regulation of proteolysis GO:0030162 164 0.029
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.028
regulation of cellular ketone metabolic process GO:0010565 66 0.028
immune effector process GO:0002252 321 0.028
divalent metal ion transport GO:0070838 172 0.027
nucleoside monophosphate catabolic process GO:0009125 59 0.026
microtubule cytoskeleton organization GO:0000226 157 0.026
aromatic compound catabolic process GO:0019439 286 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
double strand break repair GO:0006302 48 0.026
female meiosis chromosome segregation GO:0016321 1 0.026
digestive tract development GO:0048565 190 0.025
purine containing compound metabolic process GO:0072521 311 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
maintenance of location GO:0051235 89 0.024
ribonucleoside catabolic process GO:0042454 206 0.024
dna catabolic process exonucleolytic GO:0000738 3 0.024
cellular ketone metabolic process GO:0042180 84 0.024
endomembrane system organization GO:0010256 147 0.023
response to acid chemical GO:0001101 111 0.023
sister chromatid cohesion GO:0007062 12 0.023
covalent chromatin modification GO:0016569 163 0.023
positive regulation of cellular catabolic process GO:0031331 148 0.023
response to radiation GO:0009314 165 0.023
protein complex disassembly GO:0043241 40 0.023
hepaticobiliary system development GO:0061008 67 0.023
cellularization GO:0007349 1 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
modification dependent protein catabolic process GO:0019941 133 0.022
nucleotide catabolic process GO:0009166 217 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
regulation of hydrolase activity GO:0051336 246 0.022
germ cell development GO:0007281 185 0.022
chromatin modification GO:0016568 187 0.021
cellular protein catabolic process GO:0044257 155 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
protein processing GO:0016485 163 0.021
gene silencing GO:0016458 38 0.021
regulation of protein catabolic process GO:0042176 108 0.021
leukocyte migration GO:0050900 124 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
cation transport GO:0006812 399 0.020
blood vessel morphogenesis GO:0048514 285 0.020
immunoglobulin mediated immune response GO:0016064 69 0.020
production of molecular mediator of immune response GO:0002440 103 0.020
negative regulation of molecular function GO:0044092 258 0.020
ribonucleotide catabolic process GO:0009261 208 0.020
negative regulation of organelle organization GO:0010639 90 0.020
protein maturation GO:0051604 176 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
adaptive immune response GO:0002250 155 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
protein localization to organelle GO:0033365 185 0.019
organelle localization GO:0051640 179 0.019
purine ribonucleotide catabolic process GO:0009154 208 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
lymphocyte activation involved in immune response GO:0002285 93 0.019
regulation of microtubule cytoskeleton organization GO:0070507 37 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
regulation of mapk cascade GO:0043408 248 0.019
regulation of cell division GO:0051302 76 0.019
striated muscle tissue development GO:0014706 293 0.019
cellular protein complex assembly GO:0043623 116 0.018
protein localization to chromosome centromeric region GO:0071459 1 0.018
endocytosis GO:0006897 168 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
response to organonitrogen compound GO:0010243 246 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
organophosphate catabolic process GO:0046434 232 0.018
negative regulation of protein processing GO:0010955 79 0.018
dna biosynthetic process GO:0071897 22 0.018
cell adhesion GO:0007155 329 0.017
establishment of meiotic spindle orientation GO:0051296 1 0.017
guanosine containing compound catabolic process GO:1901069 144 0.017
regulation of cellular component size GO:0032535 121 0.017
cellular amine metabolic process GO:0044106 44 0.017
negative regulation of cytoskeleton organization GO:0051494 36 0.017
meiotic dna repair synthesis GO:0000711 4 0.017
oxidation reduction process GO:0055114 342 0.017
dna endoreduplication GO:0042023 4 0.017
establishment of organelle localization GO:0051656 122 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.016
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.016
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.016
divalent inorganic cation transport GO:0072511 178 0.016
wnt signaling pathway GO:0016055 188 0.016
b cell activation GO:0042113 161 0.016
nucleotide metabolic process GO:0009117 332 0.016
dna catabolic process endonucleolytic GO:0000737 15 0.016
microtubule polymerization or depolymerization GO:0031109 26 0.016
leukocyte mediated immunity GO:0002443 174 0.016
regulation of cytokine production GO:0001817 266 0.016
forebrain development GO:0030900 302 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.015
negative regulation of cell development GO:0010721 169 0.015
cellular response to biotic stimulus GO:0071216 92 0.015
Human
cytokine production GO:0001816 319 0.015
regulation of chromatin silencing GO:0031935 2 0.015
b cell activation involved in immune response GO:0002312 50 0.015
microtubule nucleation GO:0007020 2 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
cellular homeostasis GO:0019725 240 0.015
placenta development GO:0001890 140 0.015
negative regulation of protein metabolic process GO:0051248 282 0.014
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.014
amine metabolic process GO:0009308 45 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.014
peptide hormone secretion GO:0030072 109 0.014
regulation of protein localization GO:0032880 231 0.014
protein polymerization GO:0051258 57 0.014
b cell mediated immunity GO:0019724 71 0.014
cell cycle g1 s phase transition GO:0044843 57 0.014
spindle assembly involved in female meiosis GO:0007056 3 0.014
anatomical structure homeostasis GO:0060249 145 0.014
mapk cascade GO:0000165 281 0.014
mitotic nuclear division GO:0007067 48 0.013
regulation of anatomical structure size GO:0090066 178 0.013
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.013
spindle localization GO:0051653 22 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
membrane organization GO:0061024 245 0.013
protein depolymerization GO:0051261 34 0.013
regulation of mitotic spindle organization GO:0060236 2 0.013
positive regulation of cellular protein catabolic process GO:1903364 34 0.013
chromatin organization GO:0006325 206 0.013
negative regulation of phosphorus metabolic process GO:0010563 184 0.013
regulation of mitotic sister chromatid segregation GO:0033047 12 0.013
nuclear transport GO:0051169 139 0.013
positive regulation of histone methylation GO:0031062 16 0.013
dna recombination GO:0006310 92 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of cell cycle g2 m phase transition GO:1902749 10 0.013
positive regulation of nucleoside metabolic process GO:0045979 91 0.013
establishment or maintenance of cell polarity GO:0007163 86 0.013
protein ubiquitination GO:0016567 171 0.013
regionalization GO:0003002 337 0.013
negative regulation of cell cycle GO:0045786 123 0.012
mitotic centrosome separation GO:0007100 4 0.012
lymphocyte mediated immunity GO:0002449 139 0.012
leukocyte activation involved in immune response GO:0002366 126 0.012
regulation of cellular response to stress GO:0080135 159 0.012
ossification GO:0001503 216 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
negative regulation of cellular protein metabolic process GO:0032269 247 0.012
rhythmic process GO:0048511 174 0.012
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.012
regulation of neuron differentiation GO:0045664 281 0.012
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.012
response to mineralocorticoid GO:0051385 1 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
histone monoubiquitination GO:0010390 3 0.012
humoral immune response GO:0006959 57 0.012
somatic diversification of immune receptors GO:0002200 53 0.012
positive regulation of chromatin modification GO:1903310 28 0.012
negative regulation of cell size GO:0045792 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 58 0.012
positive regulation of nervous system development GO:0051962 221 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
digestive system development GO:0055123 200 0.011
regulation of lymphocyte mediated immunity GO:0002706 84 0.011
regulation of secretion GO:0051046 274 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
negative regulation of protein modification process GO:0031400 163 0.011
negative regulation of mitotic cell cycle GO:0045930 58 0.011
skeletal system development GO:0001501 356 0.011
signal transduction by p53 class mediator GO:0072331 51 0.011
positive regulation of oocyte development GO:0060282 4 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
dephosphorylation GO:0016311 129 0.011
positive regulation of protein modification process GO:0031401 299 0.011
regulation of cell motility GO:2000145 236 0.011
regulation of secretion by cell GO:1903530 249 0.011
positive regulation of cell cycle phase transition GO:1901989 17 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.011
regulation of spindle organization GO:0090224 2 0.011
liver development GO:0001889 66 0.011
purine ribonucleotide metabolic process GO:0009150 290 0.011
regulation of cellular protein catabolic process GO:1903362 61 0.011
negative regulation of protein depolymerization GO:1901880 21 0.011
regulation of histone methylation GO:0031060 30 0.011
intracellular protein transport GO:0006886 204 0.011
t cell activation GO:0042110 289 0.011
peptide secretion GO:0002790 114 0.010
mrna processing GO:0006397 63 0.010
cellular macromolecule catabolic process GO:0044265 206 0.010
nucleoside monophosphate metabolic process GO:0009123 85 0.010
maintenance of dna methylation GO:0010216 4 0.010
regulation of membrane potential GO:0042391 192 0.010
positive regulation of mitotic cell cycle phase transition GO:1901992 17 0.010
atp metabolic process GO:0046034 75 0.010
dna dependent dna replication GO:0006261 24 0.010
negative regulation of gene expression epigenetic GO:0045814 15 0.010
lymphocyte differentiation GO:0030098 242 0.010
somatic diversification of immunoglobulins GO:0016445 43 0.010
negative regulation of immune system process GO:0002683 209 0.010
mitotic spindle organization GO:0007052 10 0.010
sensory perception GO:0007600 245 0.010
reciprocal dna recombination GO:0035825 16 0.010
meiosis ii GO:0007135 7 0.010

Eme1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.103
immune system disease DOID:2914 0 0.103
aplastic anemia DOID:12449 0 0.103
disease of anatomical entity DOID:7 0 0.103
bone marrow disease DOID:4961 0 0.103
anemia DOID:2355 0 0.103
hematopoietic system disease DOID:74 0 0.103
cancer DOID:162 0 0.054
disease of cellular proliferation DOID:14566 0 0.054
organ system cancer DOID:0050686 0 0.047
gastrointestinal system cancer DOID:3119 0 0.040
intestinal cancer DOID:10155 0 0.040
thoracic cancer DOID:5093 0 0.019
nervous system disease DOID:863 0 0.016
large intestine cancer DOID:5672 0 0.015
fanconi s anemia DOID:13636 0 0.014
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
colorectal cancer DOID:9256 0 0.013