|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.186
|
|
|
protein methylation
|
GO:0006479 |
81 |
0.122
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.074
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.068
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.067
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.063
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.059
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.052
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.047
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.047
|
|
|
protein processing
|
GO:0016485 |
163 |
0.047
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.046
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.046
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.044
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.044
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.042
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.041
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.040
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.037
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.034
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.032
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.032
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.031
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.031
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.031
|
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.031
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.031
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.031
|
|
|
translation
|
GO:0006412 |
93 |
0.030
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.030
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.029
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.029
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.029
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.028
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.028
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.028
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.028
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.027
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.027
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.027
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.026
|
|
|
limb development
|
GO:0060173 |
166 |
0.026
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.026
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.026
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.025
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.025
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.025
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.024
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.024
|
|
|
ear development
|
GO:0043583 |
200 |
0.024
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.024
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.024
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.024
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.023
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.023
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.023
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.023
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
43 |
0.023
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.023
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.023
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.023
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.023
|
|
|
rna splicing via transesterification reactions with bulged adenosine as nucleophile
|
GO:0000377 |
43 |
0.022
|
|
|
ossification
|
GO:0001503 |
216 |
0.022
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.022
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.022
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.021
|
|
|
appendage development
|
GO:0048736 |
166 |
0.021
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.021
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.021
|
|
|
hepaticobiliary system development
|
GO:0061008 |
67 |
0.021
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.021
|
|
|
gonad development
|
GO:0008406 |
141 |
0.021
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.021
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.020
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.020
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.020
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.020
|
|
|
methylation
|
GO:0032259 |
134 |
0.020
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.020
|
|
|
regulation of translation
|
GO:0006417 |
71 |
0.020
|
|
|
cation transport
|
GO:0006812 |
399 |
0.020
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.019
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.019
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.019
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.019
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.019
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.019
|
|
|
oocyte axis specification
|
GO:0007309 |
2 |
0.019
|
|
|
gland development
|
GO:0048732 |
330 |
0.019
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.019
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.019
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.018
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.018
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.018
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.018
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.018
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.018
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.018
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.018
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.018
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.017
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.017
|
|
|
meiosis i
|
GO:0007127 |
60 |
0.017
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.017
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.017
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.017
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.017
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.017
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.017
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.016
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.016
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.016
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.016
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.016
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.016
|
|
|
response to epidermal growth factor
|
GO:0070849 |
4 |
0.016
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.016
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.016
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.016
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.016
|
|
|
regulation of viral transcription
|
GO:0046782 |
3 |
0.016
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.016
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.015
|
|
|
actin mediated cell contraction
|
GO:0070252 |
15 |
0.015
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.015
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.015
|
|
|
anion transport
|
GO:0006820 |
177 |
0.015
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.015
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.015
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.015
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.015
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.015
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.015
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.014
|
|
|
positive regulation of histone h3 k9 methylation
|
GO:0051574 |
4 |
0.014
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.014
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.014
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.014
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.014
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.014
|
|
|
viral transcription
|
GO:0019083 |
3 |
0.014
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.014
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.014
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.014
|
|
|
histone modification
|
GO:0016570 |
159 |
0.014
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
33 |
0.014
|
|
|
cellularization
|
GO:0007349 |
1 |
0.014
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.014
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.013
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.013
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.013
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.013
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.013
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.013
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.013
|
|
|
skin development
|
GO:0043588 |
220 |
0.013
|
|
|
cellular response to epidermal growth factor stimulus
|
GO:0071364 |
4 |
0.013
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.013
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.013
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.013
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.013
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.013
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.013
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.013
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.013
|
|
|
viral process
|
GO:0016032 |
41 |
0.013
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.013
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.013
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.013
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.013
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.012
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.012
|
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.012
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.012
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.012
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.012
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.012
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
2 |
0.012
|
|
|
lung development
|
GO:0030324 |
164 |
0.012
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.012
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.012
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.012
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.012
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.012
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.012
|
|
|
heart process
|
GO:0003015 |
94 |
0.012
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.012
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.012
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.012
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.012
|
|
|
sensory perception of sound
|
GO:0007605 |
97 |
0.012
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.012
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.012
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.012
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
46 |
0.012
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.012
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.012
|
|
|
cytoplasmic mrna processing body assembly
|
GO:0033962 |
6 |
0.012
|
|
|
placenta development
|
GO:0001890 |
140 |
0.012
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.012
|
|
|
rna processing
|
GO:0006396 |
105 |
0.012
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.011
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.011
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.011
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.011
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.011
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.011
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.011
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.011
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.011
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.011
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.011
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.011
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.011
|
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.011
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.011
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.011
|
|
|
regulation of histone modification
|
GO:0031056 |
56 |
0.011
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.011
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.011
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.011
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.011
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.011
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.011
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.011
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.011
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.011
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.011
|
|
|
cellular response to radiation
|
GO:0071478 |
28 |
0.011
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.011
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.011
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.011
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.011
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.010
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.010
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
22 |
0.010
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.010
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.010
|
|
|
male meiosis i
|
GO:0007141 |
16 |
0.010
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.010
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
22 |
0.010
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.010
|
|
|
membrane tubulation
|
GO:0097320 |
4 |
0.010
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.010
|
|
|
embryonic digestive tract development
|
GO:0048566 |
27 |
0.010
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.010
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.010
|
|
|
histone methylation
|
GO:0016571 |
71 |
0.010
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.010
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.010
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.010
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.010
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
7 |
0.010
|
|