Mus musculus

0 known processes

Stat2

signal transducer and activator of transcription 2

(Aliases: AW496480,1600010G07Rik)

Stat2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.971
Mouse
response to type i interferon GO:0034340 12 0.969
Mouse
viral process GO:0016032 41 0.958
cellular response to type i interferon GO:0071357 10 0.950
Mouse
positive t cell selection GO:0043368 23 0.900
Mouse
interferon beta biosynthetic process GO:0045350 4 0.828
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.823
t helper 17 cell lineage commitment GO:0072540 4 0.821
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.817
viral life cycle GO:0019058 36 0.811
type i interferon signaling pathway GO:0060337 10 0.806
Mouse
t helper cell differentiation GO:0042093 28 0.799
Mouse
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.791
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.786
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.767
interspecies interaction between organisms GO:0044419 83 0.764
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.743
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.736
negative regulation of interferon beta production GO:0032688 3 0.730
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.708
Mouse
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.690
regulation of innate immune response GO:0045088 91 0.664
Mouse
alpha beta t cell lineage commitment GO:0002363 7 0.662
Mouse
necrotic cell death GO:0070265 30 0.659
t cell lineage commitment GO:0002360 13 0.650
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.641
Mouse
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.639
myeloid cell differentiation GO:0030099 233 0.636
Mouse
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.624
Mouse
t cell differentiation involved in immune response GO:0002292 30 0.620
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.612
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.605
Mouse
regulation of interferon beta biosynthetic process GO:0045357 4 0.592
regulation of t cell proliferation GO:0042129 92 0.588
Mouse
cellular response to biotic stimulus GO:0071216 92 0.581
Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.569
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.558
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.544
Mouse
positive regulation of viral entry into host cell GO:0046598 3 0.536
lymphocyte mediated immunity GO:0002449 139 0.536
Mouse
regulation of t cell activation GO:0050863 170 0.531
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 40 0.525
Mouse
macromolecule methylation GO:0043414 120 0.520
myeloid dendritic cell differentiation GO:0043011 16 0.519
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.515
t helper cell lineage commitment GO:0002295 6 0.506
Mouse
negative regulation of immune effector process GO:0002698 55 0.499
lymphocyte activation involved in immune response GO:0002285 93 0.496
Mouse
leukocyte differentiation GO:0002521 342 0.494
Mouse
negative regulation of t cell activation GO:0050868 65 0.487
activation of immune response GO:0002253 138 0.485
positive regulation of cytokine production GO:0001819 174 0.483
Mouse
immune response activating signal transduction GO:0002757 116 0.478
negative regulation of regulatory t cell differentiation GO:0045590 2 0.469
alpha beta t cell differentiation GO:0046632 69 0.464
Mouse
phagocytosis GO:0006909 66 0.464
positive regulation of innate immune response GO:0045089 80 0.461
Mouse
t cell activation GO:0042110 289 0.455
Mouse
erythrocyte differentiation GO:0030218 88 0.448
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.436
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.429
Mouse
internal protein amino acid acetylation GO:0006475 42 0.428
response to dsrna GO:0043331 30 0.423
Mouse
histone h4 acetylation GO:0043967 10 0.421
regulation of cell activation GO:0050865 289 0.417
Mouse
negative regulation of immune system process GO:0002683 209 0.411
Mouse
defense response to protozoan GO:0042832 25 0.400
negative regulation of multi organism process GO:0043901 68 0.399
immune response regulating signaling pathway GO:0002764 125 0.383
toll like receptor signaling pathway GO:0002224 38 0.382
regulation of lymphocyte activation GO:0051249 240 0.379
Mouse
negative regulation of viral genome replication GO:0045071 10 0.376
growth involved in symbiotic interaction GO:0044110 23 0.371
glycosyl compound metabolic process GO:1901657 246 0.369
methylation GO:0032259 134 0.360
growth of symbiont involved in interaction with host GO:0044116 23 0.360
peptidyl lysine methylation GO:0018022 29 0.359
response to interferon gamma GO:0034341 34 0.358
Mouse
mammary gland epithelium development GO:0061180 65 0.355
Mouse
positive regulation of response to cytokine stimulus GO:0060760 11 0.355
response to molecule of bacterial origin GO:0002237 143 0.345
Mouse
adaptive immune response GO:0002250 155 0.343
Mouse
t helper 17 type immune response GO:0072538 9 0.341
regulation of leukocyte proliferation GO:0070663 121 0.337
Mouse
negative regulation of cell activation GO:0050866 111 0.337
negative regulation of t cell differentiation GO:0045581 23 0.335
t cell selection GO:0045058 34 0.335
Mouse
regulation of protein complex assembly GO:0043254 83 0.329
myeloid leukocyte differentiation GO:0002573 119 0.329
Mouse
regulation of cytokine production GO:0001817 266 0.326
Mouse
t cell differentiation GO:0030217 174 0.324
Mouse
positive regulation of type i interferon production GO:0032481 14 0.321
regulation of leukocyte differentiation GO:1902105 159 0.319
Mouse
negative regulation of viral process GO:0048525 23 0.318
positive regulation of cellular component biogenesis GO:0044089 94 0.315
gland development GO:0048732 330 0.314
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.307
cytokine mediated signaling pathway GO:0019221 115 0.307
Mouse
cell activation involved in immune response GO:0002263 126 0.306
Mouse
epidermis development GO:0008544 187 0.302
alpha beta t cell activation GO:0046631 91 0.301
Mouse
myeloid cell homeostasis GO:0002262 114 0.301
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.299
regulation of toll like receptor signaling pathway GO:0034121 20 0.299
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.298
protein methylation GO:0006479 81 0.298
negative regulation of defense response to virus by host GO:0050689 1 0.295
lymphocyte differentiation GO:0030098 242 0.294
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.290
cellular response to interferon gamma GO:0071346 25 0.282
Mouse
chromatin organization GO:0006325 206 0.280
negative regulation of leukocyte differentiation GO:1902106 51 0.277
protein modification by small protein conjugation or removal GO:0070647 207 0.262
citrate metabolic process GO:0006101 3 0.259
Mouse
interferon beta production GO:0032608 16 0.256
gene silencing by mirna GO:0035195 10 0.256
natural killer cell proliferation GO:0001787 3 0.255
Mouse
mast cell proliferation GO:0070662 4 0.254
Mouse
cytokine production GO:0001816 319 0.252
Mouse
interleukin 12 biosynthetic process GO:0042090 8 0.251
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.249
programmed necrotic cell death GO:0097300 28 0.240
t helper 17 cell differentiation GO:0072539 7 0.236
chromatin modification GO:0016568 187 0.234
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.234
interferon gamma mediated signaling pathway GO:0060333 5 0.233
Mouse
response to protozoan GO:0001562 28 0.225
protein alkylation GO:0008213 81 0.224
regulation of regulatory t cell differentiation GO:0045589 7 0.215
viral genome replication GO:0019079 17 0.211
histone h3 acetylation GO:0043966 14 0.210
protein ubiquitination GO:0016567 171 0.209
cytokine biosynthetic process GO:0042089 68 0.206
Mouse
negative regulation of defense response GO:0031348 77 0.204
regulation of alpha beta t cell activation GO:0046634 53 0.202
alpha beta t cell proliferation GO:0046633 21 0.199
purine containing compound catabolic process GO:0072523 213 0.199
response to interleukin 15 GO:0070672 3 0.198
Mouse
histone modification GO:0016570 159 0.197
covalent chromatin modification GO:0016569 163 0.193
keratinocyte proliferation GO:0043616 21 0.192
epithelial cell proliferation GO:0050673 174 0.185
Mouse
activation of innate immune response GO:0002218 56 0.184
keratinocyte differentiation GO:0030216 48 0.180
defense response to virus GO:0051607 68 0.179
skin development GO:0043588 220 0.178
nucleotide metabolic process GO:0009117 332 0.178
growth of symbiont in host GO:0044117 23 0.175
innate immune response GO:0045087 157 0.174
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.173
regulatory t cell differentiation GO:0045066 10 0.173
positive regulation of protein complex assembly GO:0031334 45 0.171
aromatic compound catabolic process GO:0019439 286 0.170
negative regulation of response to biotic stimulus GO:0002832 10 0.168
positive regulation of dna templated transcription initiation GO:2000144 5 0.163
mammary gland epithelial cell differentiation GO:0060644 13 0.162
posttranscriptional gene silencing GO:0016441 10 0.156
regulation of defense response to virus by host GO:0050691 8 0.154
histone acetylation GO:0016573 41 0.152
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.151
regulation of cytokine biosynthetic process GO:0042035 59 0.151
Mouse
ribose phosphate metabolic process GO:0019693 291 0.150
negative regulation of cellular component organization GO:0051129 194 0.148
Mouse
regulation of response to cytokine stimulus GO:0060759 23 0.146
myeloid leukocyte activation GO:0002274 83 0.145
regulation of natural killer cell differentiation GO:0032823 11 0.143
Mouse
t helper 1 cell lineage commitment GO:0002296 2 0.143
Mouse
cell adhesion GO:0007155 329 0.141
Mouse
protein modification by small protein conjugation GO:0032446 187 0.141
regulation of alpha beta t cell proliferation GO:0046640 18 0.139
negative regulation of glycolytic process GO:0045820 4 0.139
Mouse
response to organic cyclic compound GO:0014070 198 0.137
Mouse
positive regulation of viral genome replication GO:0045070 2 0.135
regulation of type i interferon production GO:0032479 22 0.134
purine nucleotide metabolic process GO:0006163 302 0.130
negative regulation of protein metabolic process GO:0051248 282 0.130
regulation of viral genome replication GO:0045069 13 0.129
cellular response to lipid GO:0071396 145 0.128
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.126
Mouse
interferon gamma production GO:0032609 67 0.126
regulation of cellular catabolic process GO:0031329 242 0.124
Mouse
innate immune response activating signal transduction GO:0002758 50 0.124
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.124
somatic diversification of immune receptors GO:0002200 53 0.123
Mouse
myd88 dependent toll like receptor signaling pathway GO:0002755 7 0.123
organophosphate catabolic process GO:0046434 232 0.122
cd8 positive alpha beta t cell activation GO:0036037 9 0.121
regulation of natural killer cell activation GO:0032814 22 0.120
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.120
internal peptidyl lysine acetylation GO:0018393 42 0.118
regulation of interleukin 12 production GO:0032655 30 0.117
negative regulation of lymphocyte differentiation GO:0045620 32 0.117
positive regulation of binding GO:0051099 49 0.116
negative regulation of growth GO:0045926 99 0.115
taurine metabolic process GO:0019530 4 0.113
Mouse
t cell activation involved in immune response GO:0002286 43 0.112
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.112
cell fate commitment GO:0045165 210 0.111
Mouse
positive regulation of interferon beta production GO:0032728 8 0.111
b cell activation involved in immune response GO:0002312 50 0.109
Mouse
rna interference GO:0016246 2 0.109
dna templated transcription initiation GO:0006352 13 0.109
creatine metabolic process GO:0006600 4 0.109
Mouse
defense response to bacterium GO:0042742 119 0.108
homeostasis of number of cells GO:0048872 210 0.106
Mouse
regulation of b cell differentiation GO:0045577 23 0.105
Mouse
nlrp3 inflammasome complex assembly GO:0044546 5 0.104
b cell activation GO:0042113 161 0.102
Mouse
negative regulation of cell proliferation GO:0008285 296 0.101
Mouse
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.101
cellular response to cytokine stimulus GO:0071345 189 0.101
Mouse
alpha amino acid metabolic process GO:1901605 59 0.100
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.099
macromolecule glycosylation GO:0043413 55 0.099
nucleoside triphosphate metabolic process GO:0009141 230 0.096
protein acylation GO:0043543 64 0.096
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.095
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.094
regulation of interferon gamma production GO:0032649 57 0.094
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.092
Mouse
regulation of mast cell apoptotic process GO:0033025 5 0.092
Mouse
modulation of growth of symbiont involved in interaction with host GO:0044144 19 0.092
defense response to other organism GO:0098542 197 0.092
regulation of interferon beta production GO:0032648 13 0.090
purine ribonucleoside metabolic process GO:0046128 241 0.089
type i interferon production GO:0032606 29 0.089
ribonucleotide metabolic process GO:0009259 291 0.088
peptidyl lysine modification GO:0018205 77 0.087
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.085
negative regulation of cytokine biosynthetic process GO:0042036 13 0.085
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.084
Mouse
carbohydrate metabolic process GO:0005975 230 0.084
Mouse
regulation of mast cell differentiation GO:0060375 3 0.083
Mouse
regulation of neuron migration GO:2001222 22 0.082
Mouse
development of secondary male sexual characteristics GO:0046544 3 0.082
Mouse
regulation of reactive oxygen species metabolic process GO:2000377 40 0.082
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.082
Mouse
leukocyte mediated immunity GO:0002443 174 0.082
Mouse
regulation of defense response to virus GO:0050688 18 0.079
regulation of actin nucleation GO:0051125 4 0.079
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.077
organelle assembly GO:0070925 177 0.076
macrophage fusion GO:0034238 3 0.075
Mouse
nucleoside metabolic process GO:0009116 246 0.075
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.074
Mouse
natural killer cell mediated immunity GO:0002228 29 0.074
Mouse
protein catabolic process GO:0030163 221 0.074
regulation of translation GO:0006417 71 0.073
b cell differentiation GO:0030183 78 0.072
Mouse
nucleoside catabolic process GO:0009164 206 0.071
purine nucleotide catabolic process GO:0006195 211 0.071
endocytosis GO:0006897 168 0.070
cellular response to growth factor stimulus GO:0071363 197 0.070
Mouse
regulation of cell migration GO:0030334 219 0.070
Mouse
regulation of defense response GO:0031347 233 0.069
Mouse
multicellular organism growth GO:0035264 161 0.069
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.069
Mouse
cellular nitrogen compound catabolic process GO:0044270 280 0.068
macromolecule catabolic process GO:0009057 281 0.068
regulation of cell motility GO:2000145 236 0.068
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.068
rig i signaling pathway GO:0039529 4 0.067
lipid homeostasis GO:0055088 63 0.067
Mouse
immune effector process GO:0002252 321 0.067
Mouse
dendritic cell differentiation GO:0097028 26 0.067
posttranscriptional gene silencing by rna GO:0035194 10 0.066
positive regulation of interleukin 12 production GO:0032735 21 0.065
regulation of leukocyte mediated immunity GO:0002703 104 0.065
Mouse
regulation of multi organism process GO:0043900 111 0.065
purine containing compound metabolic process GO:0072521 311 0.065
regulation of dna binding GO:0051101 39 0.063
peptidyl lysine acetylation GO:0018394 45 0.063
peptidyl amino acid modification GO:0018193 336 0.062
Mouse
regulation of natural killer cell proliferation GO:0032817 2 0.062
Mouse
negative regulation of cell development GO:0010721 169 0.060
Mouse
regulation of binding GO:0051098 111 0.060
regulation of macrophage fusion GO:0034239 3 0.060
Mouse
negative regulation of growth of symbiont in host GO:0044130 19 0.059
positive regulation of defense response GO:0031349 124 0.058
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.058
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.058
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.058
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.057
posttranscriptional regulation of gene expression GO:0010608 155 0.057
negative regulation of cytokine production GO:0001818 84 0.056
creatinine metabolic process GO:0046449 3 0.056
Mouse
response to interleukin 4 GO:0070670 23 0.056
Mouse
pre mirna processing GO:0031054 3 0.056
interleukin 12 production GO:0032615 32 0.055
positive regulation of cell activation GO:0050867 158 0.055
Mouse
hormone metabolic process GO:0042445 86 0.055
Mouse
positive regulation of natural killer cell activation GO:0032816 15 0.054
Mouse
regulation of dna templated transcription initiation GO:2000142 7 0.054
regulation of t cell differentiation GO:0045580 83 0.054
Mouse
negative regulation of defense response to virus GO:0050687 6 0.053
glycoprotein biosynthetic process GO:0009101 89 0.052
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 6 0.052
ribonucleoside catabolic process GO:0042454 206 0.052
negative regulation of viral release from host cell GO:1902187 6 0.051
monocarboxylic acid metabolic process GO:0032787 191 0.051
Mouse
glycolytic process GO:0006096 20 0.050
Mouse
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.050
Mouse
protein processing GO:0016485 163 0.050
Mouse
ribonucleoside metabolic process GO:0009119 245 0.049
cellular lipid metabolic process GO:0044255 323 0.049
Mouse
regulation of mast cell proliferation GO:0070666 4 0.049
Mouse
cellular response to peptide GO:1901653 92 0.049
Mouse
gtp metabolic process GO:0046039 144 0.048
response to interferon alpha GO:0035455 7 0.047
nucleoside phosphate metabolic process GO:0006753 338 0.047
cell type specific apoptotic process GO:0097285 268 0.047
Mouse
cellular protein complex assembly GO:0043623 116 0.047
glycosylation GO:0070085 62 0.047
carbohydrate derivative biosynthetic process GO:1901137 183 0.047
translation GO:0006412 93 0.046
cellular response to interleukin 4 GO:0071353 21 0.046
Mouse
regulation of viral release from host cell GO:1902186 6 0.046
gene silencing by rna GO:0031047 19 0.045
type i interferon biosynthetic process GO:0045351 9 0.045
guanosine containing compound catabolic process GO:1901069 144 0.045
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.044
regulation of endocytosis GO:0030100 69 0.044
regulation of hormone levels GO:0010817 211 0.044
Mouse
cytoplasmic transport GO:0016482 234 0.043
positive regulation of rig i signaling pathway GO:1900246 1 0.043
regulation of hydrolase activity GO:0051336 246 0.043
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.043
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.042
mast cell apoptotic process GO:0033024 5 0.042
Mouse
eye photoreceptor cell differentiation GO:0001754 41 0.042
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.042
isoleucine metabolic process GO:0006549 4 0.042
Mouse
rna catabolic process GO:0006401 29 0.041
positive regulation of immune effector process GO:0002699 107 0.041
Mouse
protein oligomerization GO:0051259 67 0.041
mapk cascade GO:0000165 281 0.041
regulation of body fluid levels GO:0050878 162 0.040
Mouse
positive regulation of t cell activation GO:0050870 101 0.040
Mouse
regulation of mapk cascade GO:0043408 248 0.040
negative regulation of myeloid cell differentiation GO:0045638 38 0.040
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.039
production of small rna involved in gene silencing by rna GO:0070918 6 0.039
microtubule based process GO:0007017 236 0.039
regulation of cytoskeleton organization GO:0051493 122 0.039
nucleotide catabolic process GO:0009166 217 0.039
positive regulation of dna binding GO:0043388 14 0.039
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.038
Mouse
gtp catabolic process GO:0006184 143 0.038
regulation of response to biotic stimulus GO:0002831 38 0.038
negative regulation of viral transcription GO:0032897 3 0.038
natural killer cell mediated cytotoxicity GO:0042267 29 0.038
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.038
Mouse
purine nucleoside metabolic process GO:0042278 241 0.038
glucose homeostasis GO:0042593 128 0.037
Mouse
viral gene expression GO:0019080 3 0.037
movement in host environment GO:0052126 15 0.037
regulation of neuron differentiation GO:0045664 281 0.037
regulation of adaptive immune response GO:0002819 90 0.037
Mouse
interleukin 4 mediated signaling pathway GO:0035771 2 0.037
Mouse
protein polyubiquitination GO:0000209 33 0.037
regulation of interleukin 6 production GO:0032675 55 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.036
nucleotide biosynthetic process GO:0009165 78 0.036
male gamete generation GO:0048232 285 0.036
entry into host cell GO:0030260 15 0.036
t cell proliferation GO:0042098 120 0.036
Mouse
viral transcription GO:0019083 3 0.036
negative regulation of nervous system development GO:0051961 156 0.036
Mouse
regulation of myeloid leukocyte differentiation GO:0002761 58 0.035
Mouse
positive regulation of mast cell differentiation GO:0060376 1 0.035
Mouse
lipid localization GO:0010876 126 0.035
Mouse
regulation of erythrocyte differentiation GO:0045646 23 0.034
Mouse
regulation of organelle organization GO:0033043 289 0.034
negative regulation of macrophage fusion GO:0034240 1 0.034
Mouse
maintenance of location GO:0051235 89 0.034
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.034
regulation of response to wounding GO:1903034 189 0.033
Mouse
cellular modified amino acid metabolic process GO:0006575 63 0.033
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.033
positive regulation of activated t cell proliferation GO:0042104 8 0.033
Mouse
hormone mediated signaling pathway GO:0009755 23 0.033
Mouse
regulation of interleukin 12 biosynthetic process GO:0045075 8 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.032
regulation of isotype switching to ige isotypes GO:0048293 7 0.032
Mouse
dna metabolic process GO:0006259 303 0.032
Mouse
entry into other organism involved in symbiotic interaction GO:0051828 15 0.032
positive regulation of interleukin 2 biosynthetic process GO:0045086 8 0.032
Mouse
tumor necrosis factor production GO:0032640 50 0.032
positive regulation of glial cell proliferation GO:0060252 4 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
stem cell differentiation GO:0048863 268 0.032
Mouse
spermatogenesis GO:0007283 284 0.032
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.032
Mouse
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.031
cellular response to molecule of bacterial origin GO:0071219 83 0.031
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.031
Mouse
protein import GO:0017038 101 0.031
negative regulation of interleukin 6 production GO:0032715 17 0.031
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.031
Mouse
positive regulation of lymphocyte differentiation GO:0045621 61 0.030
Mouse
ribonucleotide catabolic process GO:0009261 208 0.030
allantoin metabolic process GO:0000255 3 0.030
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.030
Mouse
multicellular organismal homeostasis GO:0048871 164 0.030
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.029
Mouse
purine nucleoside catabolic process GO:0006152 205 0.029
regulation of viral transcription GO:0046782 3 0.029
transmembrane transport GO:0055085 412 0.029
atp metabolic process GO:0046034 75 0.029
protein maturation GO:0051604 176 0.029
Mouse
regulation of rig i signaling pathway GO:0039535 2 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.028
antigen receptor mediated signaling pathway GO:0050851 64 0.028
positive regulation of protein modification process GO:0031401 299 0.028
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.028
Mouse
regulation of actin filament polymerization GO:0030833 38 0.028
spleen development GO:0048536 39 0.028
mitotic cell cycle GO:0000278 195 0.028
Mouse
ribonucleoprotein complex subunit organization GO:0071826 28 0.028
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.028
Mouse
regulation of dna recombination GO:0000018 34 0.027
Mouse
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.027
interleukin 6 production GO:0032635 58 0.027
negative regulation of neuron migration GO:2001223 6 0.027
Mouse
regulation of glycolytic process GO:0006110 10 0.027
Mouse
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.027
negative regulation of type 2 immune response GO:0002829 8 0.027
Mouse
positive regulation of proteolysis GO:0045862 85 0.027
Mouse
regulation of protein catabolic process GO:0042176 108 0.027
negative regulation of cell migration GO:0030336 59 0.027
Mouse
cation transmembrane transport GO:0098655 266 0.027
regulation of actin filament length GO:0030832 45 0.026
ovulation cycle GO:0042698 59 0.026
Mouse
cellular amino acid metabolic process GO:0006520 103 0.026
Mouse
nucleocytoplasmic transport GO:0006913 139 0.026
regulation of interleukin 2 production GO:0032663 28 0.026
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.025
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.025
Mouse
succinate metabolic process GO:0006105 4 0.025
Mouse
glycoprotein metabolic process GO:0009100 116 0.025
positive regulation of nucleotide metabolic process GO:0045981 114 0.025
regulation of transferase activity GO:0051338 263 0.025
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.025
Mouse
positive regulation of hydrolase activity GO:0051345 148 0.025
Mouse
mrna metabolic process GO:0016071 84 0.025
ion transmembrane transport GO:0034220 361 0.025
t cell receptor signaling pathway GO:0050852 46 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
positive regulation of protein phosphorylation GO:0001934 242 0.024
organic cyclic compound catabolic process GO:1901361 295 0.024
production of molecular mediator of immune response GO:0002440 103 0.024
Mouse
gene silencing GO:0016458 38 0.024
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.024
nuclear membrane organization GO:0071763 4 0.024
positive regulation of interleukin 12 biosynthetic process GO:0045084 6 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
Mouse
neuron migration GO:0001764 122 0.024
Mouse
lymphocyte proliferation GO:0046651 164 0.024
Mouse
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.024
Mouse
positive regulation of nucleotide catabolic process GO:0030813 88 0.023
negative regulation of molecular function GO:0044092 258 0.023
regulation of inflammatory response GO:0050727 147 0.023
Mouse
synaptic transmission GO:0007268 329 0.023
positive regulation of leukocyte proliferation GO:0070665 73 0.023
Mouse
lactation GO:0007595 25 0.023
Mouse
organophosphate biosynthetic process GO:0090407 122 0.023
hematopoietic progenitor cell differentiation GO:0002244 143 0.023
mammary gland morphogenesis GO:0060443 54 0.023
Mouse
mitochondrion organization GO:0007005 134 0.023
cellular response to growth hormone stimulus GO:0071378 7 0.022
Mouse
mucosal associated lymphoid tissue development GO:0048537 12 0.022
Mouse
positive regulation of adaptive immune response GO:0002821 61 0.022
Mouse
positive regulation of organelle organization GO:0010638 128 0.022
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.022
leukocyte proliferation GO:0070661 172 0.022
Mouse
cellular response to hormone stimulus GO:0032870 150 0.022
Mouse
stem cell development GO:0048864 219 0.022
Mouse
leukocyte homeostasis GO:0001776 79 0.022
Mouse
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.022
Mouse
branched chain amino acid metabolic process GO:0009081 6 0.022
Mouse
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.021
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.021
myosin filament assembly GO:0031034 2 0.021
heterocycle catabolic process GO:0046700 280 0.021
intracellular protein transport GO:0006886 204 0.021
proteasomal protein catabolic process GO:0010498 98 0.021
modification dependent protein catabolic process GO:0019941 133 0.021
regulation of cell cycle GO:0051726 281 0.021
Mouse
actin polymerization or depolymerization GO:0008154 54 0.021
progesterone metabolic process GO:0042448 4 0.021
Mouse
leukocyte apoptotic process GO:0071887 71 0.021
Mouse

Stat2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.029
disease of anatomical entity DOID:7 0 0.029
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.026
disease of metabolism DOID:0014667 0 0.024