|
|
regulation of defense response
|
GO:0031347 |
233 |
0.998
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.997
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.996
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.985
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.979
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.978
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.976
|
Human Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.975
|
Mouse |
|
|
negative regulation of nlrp3 inflammasome complex assembly
|
GO:1900226 |
2 |
0.974
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.965
|
|
|
|
positive regulation of rig i signaling pathway
|
GO:1900246 |
1 |
0.964
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.962
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.954
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.945
|
|
|
|
regulation of nlrp3 inflammasome complex assembly
|
GO:1900225 |
4 |
0.944
|
|
|
|
rig i signaling pathway
|
GO:0039529 |
4 |
0.937
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.929
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.925
|
Mouse |
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.925
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.923
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.922
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.921
|
Mouse |
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.917
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.917
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.911
|
Mouse |
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.910
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.908
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.906
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.893
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.892
|
Mouse |
|
|
viral life cycle
|
GO:0019058 |
36 |
0.887
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.884
|
Mouse |
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.884
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.882
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.881
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.877
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.872
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.871
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.868
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.864
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.854
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.851
|
Mouse |
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.848
|
Mouse |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.845
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.834
|
|
|
|
response to interferon alpha
|
GO:0035455 |
7 |
0.833
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.827
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.822
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.820
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.820
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.820
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.812
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.812
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.798
|
Mouse |
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.791
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.785
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.785
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.784
|
|
|
|
regulation of interferon alpha production
|
GO:0032647 |
5 |
0.779
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.779
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.777
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.775
|
Mouse |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.775
|
|
|
|
regulation of rig i signaling pathway
|
GO:0039535 |
2 |
0.765
|
|
|
|
positive regulation of interferon beta production
|
GO:0032728 |
8 |
0.759
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.755
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.753
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.751
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.750
|
|
|
|
viral gene expression
|
GO:0019080 |
3 |
0.739
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.716
|
Mouse |
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.698
|
Mouse |
|
|
positive regulation of viral entry into host cell
|
GO:0046598 |
3 |
0.692
|
|
|
|
negative regulation of interferon beta biosynthetic process
|
GO:0045358 |
1 |
0.692
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.690
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.686
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.684
|
Mouse |
|
|
positive regulation of mast cell differentiation
|
GO:0060376 |
1 |
0.674
|
Mouse |
|
|
autophagy
|
GO:0006914 |
45 |
0.659
|
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
3 |
0.657
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.653
|
Mouse |
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.645
|
Mouse |
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.640
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.635
|
Mouse |
|
|
interferon beta production
|
GO:0032608 |
16 |
0.626
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.622
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.618
|
Mouse |
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.617
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.614
|
Mouse |
|
|
viral process
|
GO:0016032 |
41 |
0.606
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.604
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.599
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.599
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.595
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.586
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.584
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.570
|
Mouse |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.564
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.557
|
Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.553
|
Mouse |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.549
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.533
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.525
|
Mouse |
|
|
negative regulation of defense response to virus by host
|
GO:0050689 |
1 |
0.524
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.514
|
Mouse |
|
|
response to protozoan
|
GO:0001562 |
28 |
0.508
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.504
|
Mouse |
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.503
|
|
|
|
production of small rna involved in gene silencing by rna
|
GO:0070918 |
6 |
0.502
|
|
|
|
cellular response to interferon beta
|
GO:0035458 |
21 |
0.499
|
Human |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.496
|
Mouse |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.495
|
|
|
|
regulation of type i interferon production
|
GO:0032479 |
22 |
0.488
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.479
|
Mouse |
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.471
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.469
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.465
|
Mouse |
|
|
natural killer cell degranulation
|
GO:0043320 |
3 |
0.463
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.456
|
Mouse |
|
|
negative regulation of viral process
|
GO:0048525 |
23 |
0.456
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
3 |
0.455
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.448
|
|
|
|
positive regulation of viral genome replication
|
GO:0045070 |
2 |
0.447
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.441
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.437
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.434
|
Mouse |
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.430
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.429
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.425
|
Mouse |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.423
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.422
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.421
|
|
|
|
regulation of actin nucleation
|
GO:0051125 |
4 |
0.414
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.405
|
Mouse |
|
|
pre mirna processing
|
GO:0031054 |
3 |
0.404
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.389
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.387
|
|
|
|
mda 5 signaling pathway
|
GO:0039530 |
1 |
0.385
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway in response to virus
|
GO:0039528 |
4 |
0.383
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.381
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.380
|
Mouse |
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.376
|
Mouse |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.374
|
Mouse |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.367
|
|
|
|
negative regulation of interferon alpha production
|
GO:0032687 |
1 |
0.359
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.358
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.357
|
Mouse |
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.354
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.353
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.352
|
Mouse |
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.351
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.348
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.342
|
Mouse |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.338
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.335
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.333
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.333
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.327
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.323
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.323
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.320
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.307
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.305
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.302
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.302
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.300
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.298
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.290
|
Mouse |
|
|
negative regulation of interferon beta production
|
GO:0032688 |
3 |
0.290
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.284
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
13 |
0.283
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.277
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.274
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.271
|
|
|
|
nlrp3 inflammasome complex assembly
|
GO:0044546 |
5 |
0.269
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.257
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.250
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.248
|
|
|
|
histone acetylation
|
GO:0016573 |
41 |
0.246
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.242
|
|
|
|
negative regulation of viral release from host cell
|
GO:1902187 |
6 |
0.242
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.241
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.241
|
|
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.239
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.237
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.234
|
Mouse |
|
|
response to dsrna
|
GO:0043331 |
30 |
0.232
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.224
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.224
|
|
|
|
positive regulation of viral process
|
GO:0048524 |
5 |
0.219
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.218
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.217
|
Mouse |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.217
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.216
|
|
|
|
isg15 protein conjugation
|
GO:0032020 |
4 |
0.216
|
|
|
|
regulation of cd8 positive alpha beta t cell proliferation
|
GO:2000564 |
1 |
0.213
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.211
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.209
|
|
|
|
development of secondary male sexual characteristics
|
GO:0046544 |
3 |
0.208
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.207
|
|
|
|
valine metabolic process
|
GO:0006573 |
4 |
0.204
|
Mouse |
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.201
|
Mouse |
|
|
interferon alpha production
|
GO:0032607 |
7 |
0.201
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.197
|
|
|
|
negative regulation of defense response to virus
|
GO:0050687 |
6 |
0.195
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.194
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.193
|
|
|
|
adhesion of symbiont to host
|
GO:0044406 |
8 |
0.192
|
|
|
|
iron ion homeostasis
|
GO:0055072 |
36 |
0.191
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.191
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.190
|
|
|
|
regulation of glycolytic process
|
GO:0006110 |
10 |
0.189
|
Mouse |
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.188
|
|
|
|
entry into cell of other organism involved in symbiotic interaction
|
GO:0051806 |
15 |
0.187
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.187
|
|
|
|
mast cell apoptotic process
|
GO:0033024 |
5 |
0.186
|
Mouse |
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.185
|
Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.183
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.182
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.182
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.182
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.181
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.180
|
Mouse |
|
|
interaction with host
|
GO:0051701 |
22 |
0.180
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.179
|
Mouse |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.178
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.178
|
Mouse |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.178
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.178
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.177
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.176
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.175
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.175
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.173
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.172
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.169
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.168
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.167
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.166
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.163
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.162
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.162
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.161
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.160
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.160
|
Mouse |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.160
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.157
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.157
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.156
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.156
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.154
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.152
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.151
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.150
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.150
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.150
|
|
|
|
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway
|
GO:0039531 |
2 |
0.149
|
|
|
|
movement in host environment
|
GO:0052126 |
15 |
0.149
|
|
|
|
natural killer cell activation involved in immune response
|
GO:0002323 |
10 |
0.148
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.147
|
Mouse |
|
|
positive regulation of myelination
|
GO:0031643 |
5 |
0.147
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.145
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.145
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.144
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.143
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.143
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.143
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.142
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.141
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.141
|
|
|
|
schwann cell proliferation
|
GO:0014010 |
2 |
0.136
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.135
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.134
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.133
|
Mouse |
|
|
regulation of viral release from host cell
|
GO:1902186 |
6 |
0.133
|
|
|
|
t cell mediated cytotoxicity
|
GO:0001913 |
26 |
0.133
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.130
|
Mouse |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.128
|
Mouse |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.128
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.126
|
Human Mouse |
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.126
|
Mouse |
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.123
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.122
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.122
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.121
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.120
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.119
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.118
|
Mouse |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
26 |
0.117
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.117
|
|
|
|
regulation of enamel mineralization
|
GO:0070173 |
1 |
0.117
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.117
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.117
|
|
|
|
hair follicle cell proliferation
|
GO:0071335 |
3 |
0.116
|
|
|
|
regulation of viral genome replication
|
GO:0045069 |
13 |
0.116
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.116
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.116
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.116
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.115
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.115
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.115
|
Mouse |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.115
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.114
|
Mouse |
|
|
negative regulation of rig i signaling pathway
|
GO:0039536 |
2 |
0.112
|
|
|
|
creatine metabolic process
|
GO:0006600 |
4 |
0.111
|
Mouse |
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.111
|
Mouse |
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.111
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.111
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.110
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.110
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.108
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.107
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.105
|
|
|
|
regulation of schwann cell differentiation
|
GO:0014038 |
1 |
0.104
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.103
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.103
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.102
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.101
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.101
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.100
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.100
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.100
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
14 |
0.099
|
|
|
|
epithelial cell differentiation involved in prostate gland development
|
GO:0060742 |
13 |
0.099
|
Mouse |
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.099
|
|
|
|
regulation of cd8 positive alpha beta t cell activation
|
GO:2001185 |
3 |
0.098
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.097
|
Mouse |
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.096
|
Human Mouse |
|
|
stem cell development
|
GO:0048864 |
219 |
0.095
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.095
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
4 |
0.093
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.091
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.091
|
Mouse |
|
|
positive regulation of multi organism process
|
GO:0043902 |
26 |
0.091
|
|
|
|
cellular lactam metabolic process
|
GO:0072338 |
3 |
0.090
|
Mouse |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.089
|
Mouse |
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.089
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
42 |
0.089
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.088
|
Mouse |
|
|
negative regulation of interleukin 6 production
|
GO:0032715 |
17 |
0.088
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.086
|
Mouse |
|
|
cellular response to interferon alpha
|
GO:0035457 |
4 |
0.085
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.085
|
Mouse |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.084
|
Mouse |
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.084
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.084
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.084
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.083
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.082
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.081
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.080
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.080
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
3 |
0.080
|
|
|
|
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway
|
GO:0039532 |
2 |
0.078
|
|
|
|
production of mirnas involved in gene silencing by mirna
|
GO:0035196 |
6 |
0.078
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.078
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.076
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
6 |
0.076
|
Mouse |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.075
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.075
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.075
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.075
|
Mouse |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
42 |
0.074
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.074
|
Mouse |
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.074
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.074
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.073
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.073
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.073
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.073
|
Human Mouse |
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.073
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.072
|
Mouse |
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.072
|
Mouse |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.071
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.071
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.071
|
Mouse |
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.071
|
Mouse |
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.071
|
Mouse |
|
|
myoblast differentiation involved in skeletal muscle regeneration
|
GO:0014835 |
3 |
0.071
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.070
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.069
|
Mouse |
|
|
negative regulation of macrophage fusion
|
GO:0034240 |
1 |
0.069
|
|
|
|
negative regulation of viral transcription
|
GO:0032897 |
3 |
0.069
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.069
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.069
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.069
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.068
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.068
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.067
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.067
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
45 |
0.067
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.067
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.067
|
Mouse |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.066
|
|
|
|
viral genome replication
|
GO:0019079 |
17 |
0.066
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.066
|
Mouse |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.065
|
Mouse |
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.065
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.064
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.064
|
Mouse |
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.064
|
Mouse |
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.064
|
|
|
|
macrophage fusion
|
GO:0034238 |
3 |
0.063
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.062
|
Mouse |
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.062
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.062
|
|
|
|
negative regulation of viral entry into host cell
|
GO:0046597 |
10 |
0.061
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.059
|
|
|
|
positive regulation of tolerance induction dependent upon immune response
|
GO:0002654 |
1 |
0.059
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.059
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.058
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.058
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.058
|
Mouse |
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.057
|
Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.057
|
Mouse |
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.057
|
Mouse |
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.057
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.057
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.056
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.056
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.056
|
Mouse |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.056
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.055
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.055
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.055
|
Mouse |
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.055
|
Mouse |
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.054
|
Mouse |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.054
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.054
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
20 |
0.054
|
|
|
|
iron ion import into cell
|
GO:0097459 |
4 |
0.054
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.053
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.053
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.053
|
Mouse |
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.052
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.052
|
Mouse |
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.051
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.051
|
Mouse |
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.051
|
Mouse |
|
|
negative regulation of natural killer cell mediated immunity
|
GO:0002716 |
5 |
0.051
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.051
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.051
|
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.051
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.051
|
|
|
|
pyroptosis
|
GO:0070269 |
8 |
0.051
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.051
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
5 |
0.051
|
Mouse |
|
|
prostate gland morphogenesis
|
GO:0060512 |
32 |
0.050
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.050
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.050
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.050
|
Mouse |
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.050
|
Mouse |
|
|
regulation of protein deubiquitination
|
GO:0090085 |
1 |
0.050
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.050
|
Mouse |
|
|
methylation
|
GO:0032259 |
134 |
0.050
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.049
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
29 |
0.049
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.049
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway
|
GO:0002484 |
3 |
0.048
|
|
|
|
prostate gland epithelium morphogenesis
|
GO:0060740 |
31 |
0.048
|
Mouse |
|
|
segmentation
|
GO:0035282 |
93 |
0.048
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.048
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.047
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.047
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.047
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.047
|
Mouse |
|
|
zymogen activation
|
GO:0031638 |
41 |
0.047
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.047
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.047
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.047
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.047
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.047
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.047
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.047
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.046
|
Mouse |
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.046
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.046
|
|
|
|
cytotoxic t cell degranulation
|
GO:0043316 |
2 |
0.045
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.045
|
|
|
|
mammary gland epithelial cell differentiation
|
GO:0060644 |
13 |
0.045
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.045
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
25 |
0.045
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.045
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.045
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.044
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.044
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.044
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.044
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.044
|
Mouse |
|
|
negative regulation of neuron migration
|
GO:2001223 |
6 |
0.044
|
Mouse |
