Mus musculus

34 known processes

Fancd2

Fanconi anemia, complementation group D2

(Aliases: AU015151,FACD,FANCD,BB137857,FA4,2410150O07Rik,FAD,FA-D2)

Fancd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 107 0.770
male gamete generation GO:0048232 285 0.457
spermatogenesis GO:0007283 284 0.332
double strand break repair GO:0006302 48 0.331
dna recombination GO:0006310 92 0.318
double strand break repair via homologous recombination GO:0000724 21 0.301
dna metabolic process GO:0006259 303 0.251
male meiosis GO:0007140 37 0.238
cellular response to dna damage stimulus GO:0006974 207 0.238
male meiosis i GO:0007141 16 0.184
protein maturation GO:0051604 176 0.099
recombinational repair GO:0000725 21 0.072
microtubule based process GO:0007017 236 0.062
organic cyclic compound catabolic process GO:1901361 295 0.056
dna damage checkpoint GO:0000077 26 0.050
cell cycle checkpoint GO:0000075 47 0.046
regulation of mitotic cell cycle GO:0007346 126 0.046
peptidyl amino acid modification GO:0018193 336 0.045
centrosome cycle GO:0007098 23 0.044
regulation of cell cycle GO:0051726 281 0.043
regulation of cellular amine metabolic process GO:0033238 20 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.040
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.039
germ cell development GO:0007281 185 0.039
cell division GO:0051301 120 0.039
cellular nitrogen compound catabolic process GO:0044270 280 0.038
protein catabolic process GO:0030163 221 0.038
meiosis i GO:0007127 60 0.038
negative regulation of cellular component organization GO:0051129 194 0.037
macromolecule catabolic process GO:0009057 281 0.036
dna catabolic process endonucleolytic GO:0000737 15 0.035
regulation of organelle organization GO:0033043 289 0.034
regulation of mitotic cell cycle phase transition GO:1901990 73 0.034
protein processing GO:0016485 163 0.033
purine containing compound metabolic process GO:0072521 311 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
negative regulation of cell cycle process GO:0010948 69 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.032
heterocycle catabolic process GO:0046700 280 0.032
cellular amine metabolic process GO:0044106 44 0.030
negative regulation of dna replication GO:0008156 4 0.030
maintenance of location GO:0051235 89 0.029
meiotic cell cycle GO:0051321 122 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
dna integrity checkpoint GO:0031570 28 0.027
spermatid development GO:0007286 108 0.027
regulation of cell cycle process GO:0010564 160 0.026
purine ribonucleoside catabolic process GO:0046130 205 0.026
protein modification by small protein conjugation GO:0032446 187 0.026
organophosphate catabolic process GO:0046434 232 0.025
cellular protein catabolic process GO:0044257 155 0.025
negative regulation of organelle organization GO:0010639 90 0.025
gene silencing GO:0016458 38 0.025
gonad development GO:0008406 141 0.025
regulation of protein localization GO:0032880 231 0.024
nucleoside metabolic process GO:0009116 246 0.024
ribonucleotide metabolic process GO:0009259 291 0.024
methylation GO:0032259 134 0.024
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.024
anatomical structure homeostasis GO:0060249 145 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
nucleoside monophosphate metabolic process GO:0009123 85 0.023
negative regulation of cell cycle GO:0045786 123 0.023
nucleotide excision repair GO:0006289 13 0.023
negative regulation of protein metabolic process GO:0051248 282 0.023
regulation of cytoskeleton organization GO:0051493 122 0.023
nucleoside catabolic process GO:0009164 206 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.022
nucleoside triphosphate catabolic process GO:0009143 205 0.022
atp catabolic process GO:0006200 55 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
cellular ketone metabolic process GO:0042180 84 0.021
nucleotide catabolic process GO:0009166 217 0.021
ribonucleoside catabolic process GO:0042454 206 0.021
developmental maturation GO:0021700 193 0.021
cellular response to organonitrogen compound GO:0071417 145 0.021
oxidation reduction process GO:0055114 342 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 2 0.020
telomere maintenance GO:0000723 19 0.020
negative regulation of cell proliferation GO:0008285 296 0.020
cilium morphogenesis GO:0060271 102 0.019
t cell activation GO:0042110 289 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.019
regulation of cell cycle g2 m phase transition GO:1902749 10 0.019
regulation of defense response GO:0031347 233 0.019
chromatin modification GO:0016568 187 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
immune effector process GO:0002252 321 0.018
response to light stimulus GO:0009416 135 0.018
cytoplasmic transport GO:0016482 234 0.018
dna damage response signal transduction resulting in transcription GO:0042772 2 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
gland development GO:0048732 330 0.018
glycosyl compound catabolic process GO:1901658 206 0.018
mitotic cell cycle process GO:1903047 159 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.017
purine nucleoside catabolic process GO:0006152 205 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
regulation of cellular amino acid metabolic process GO:0006521 5 0.017
skeletal system development GO:0001501 356 0.017
reciprocal meiotic recombination GO:0007131 16 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
positive regulation of protein modification process GO:0031401 299 0.017
cation transport GO:0006812 399 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
reactive oxygen species metabolic process GO:0072593 84 0.016
macromolecule methylation GO:0043414 120 0.016
meiotic cell cycle process GO:1903046 77 0.016
atp metabolic process GO:0046034 75 0.016
purine containing compound catabolic process GO:0072523 213 0.016
glycoprotein biosynthetic process GO:0009101 89 0.016
apoptotic signaling pathway GO:0097190 306 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
cellular protein complex disassembly GO:0043624 36 0.016
lateral inhibition GO:0046331 1 0.016
transmembrane transport GO:0055085 412 0.016
negative regulation of cellular protein metabolic process GO:0032269 247 0.016
regulation of reactive oxygen species metabolic process GO:2000377 40 0.016
female gonad development GO:0008585 71 0.016
chromatin organization GO:0006325 206 0.016
skeletal system morphogenesis GO:0048705 203 0.016
ribonucleoside metabolic process GO:0009119 245 0.015
metaphase plate congression GO:0051310 2 0.015
meiotic nuclear division GO:0007126 115 0.015
replication fork protection GO:0048478 1 0.015
spermatid differentiation GO:0048515 115 0.015
regulation of protein catabolic process GO:0042176 108 0.015
aromatic compound catabolic process GO:0019439 286 0.015
nucleotide metabolic process GO:0009117 332 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.015
microtubule based movement GO:0007018 84 0.015
rho protein signal transduction GO:0007266 32 0.015
male sex differentiation GO:0046661 109 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.014
chromatin silencing GO:0006342 15 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
nucleoside monophosphate catabolic process GO:0009125 59 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
positive regulation of cell activation GO:0050867 158 0.014
blastocyst development GO:0001824 80 0.014
negative regulation of cellular catabolic process GO:0031330 47 0.014
dna catabolic process GO:0006308 19 0.014
regulation of protein processing GO:0070613 96 0.014
cellular homeostasis GO:0019725 240 0.013
nucleoside phosphate catabolic process GO:1901292 222 0.013
carboxylic acid biosynthetic process GO:0046394 86 0.013
ion transmembrane transport GO:0034220 361 0.013
cellular protein complex assembly GO:0043623 116 0.013
cytokine production GO:0001816 319 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.013
protein alkylation GO:0008213 81 0.013
leukocyte proliferation GO:0070661 172 0.013
purine nucleotide catabolic process GO:0006195 211 0.013
mitotic cell cycle GO:0000278 195 0.013
protein localization to organelle GO:0033365 185 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
stem cell differentiation GO:0048863 268 0.013
mitochondrion organization GO:0007005 134 0.013
rna interference GO:0016246 2 0.013
forebrain development GO:0030900 302 0.013
female sex differentiation GO:0046660 84 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
ossification GO:0001503 216 0.013
regulation of cellular catabolic process GO:0031329 242 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of production of molecular mediator of immune response GO:0002700 65 0.012
microtubule organizing center organization GO:0031023 28 0.012
development of primary female sexual characteristics GO:0046545 73 0.012
regulation of cell activation GO:0050865 289 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
centrosome organization GO:0051297 26 0.012
glycoprotein metabolic process GO:0009100 116 0.012
mapk cascade GO:0000165 281 0.012
positive regulation of lymphocyte activation GO:0051251 140 0.012
regionalization GO:0003002 337 0.012
positive regulation of cell cycle GO:0045787 92 0.012
protein targeting GO:0006605 143 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
sister chromatid segregation GO:0000819 20 0.012
response to organonitrogen compound GO:0010243 246 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
b cell activation GO:0042113 161 0.012
development of primary sexual characteristics GO:0045137 143 0.012
regulation of cytokine production GO:0001817 266 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of mapk cascade GO:0043408 248 0.011
negative regulation of mammary gland epithelial cell proliferation GO:0033600 3 0.011
small molecule biosynthetic process GO:0044283 132 0.011
cation transmembrane transport GO:0098655 266 0.011
dephosphorylation GO:0016311 129 0.011
amine metabolic process GO:0009308 45 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
carbohydrate derivative catabolic process GO:1901136 231 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of protein maturation GO:1903317 96 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
cell maturation GO:0048469 127 0.011
male gonad development GO:0008584 88 0.011
organelle assembly GO:0070925 177 0.011
lymphocyte differentiation GO:0030098 242 0.011
establishment of protein localization to organelle GO:0072594 118 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
membrane organization GO:0061024 245 0.011
cellular chemical homeostasis GO:0055082 215 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of epithelial cell proliferation GO:0050678 141 0.011
cilium assembly GO:0042384 81 0.010
mitotic cytokinesis GO:0000281 4 0.010
cell type specific apoptotic process GO:0097285 268 0.010
microtubule nucleation GO:0007020 2 0.010
cellular response to biotic stimulus GO:0071216 92 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
regulation of hormone levels GO:0010817 211 0.010
renal system development GO:0072001 225 0.010
carbohydrate derivative biosynthetic process GO:1901137 183 0.010
regulation of homeostatic process GO:0032844 182 0.010
sensory perception GO:0007600 245 0.010
protein localization to nucleus GO:0034504 121 0.010
response to gamma radiation GO:0010332 22 0.010
Human
response to insulin GO:0032868 100 0.010
epithelial cell proliferation GO:0050673 174 0.010
innate immune response GO:0045087 157 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.010
intracellular mrna localization GO:0008298 4 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
regulation of secretion by cell GO:1903530 249 0.010

Fancd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
congenital hypoplastic anemia DOID:1342 0 0.353
Human
immune system disease DOID:2914 0 0.353
Human
aplastic anemia DOID:12449 0 0.353
Human
disease of anatomical entity DOID:7 0 0.353
Human
bone marrow disease DOID:4961 0 0.353
Human
anemia DOID:2355 0 0.353
Human
hematopoietic system disease DOID:74 0 0.353
Human
thoracic cancer DOID:5093 0 0.066
cancer DOID:162 0 0.066
disease of cellular proliferation DOID:14566 0 0.066
organ system cancer DOID:0050686 0 0.066
breast cancer DOID:1612 0 0.039
fanconi s anemia DOID:13636 0 0.035
Human
endocrine gland cancer DOID:170 0 0.019
nervous system disease DOID:863 0 0.013